Uvavanyo lwe-TSH: lolwantoni kwaye kutheni liphezulu okanye liphantsi

Umxholo

• Amaxabiso esalathiso
• Zingathetha ntoni iziphumo
• I-TSH ephezulu
• I-TSH ephantsi
• Uviwo lwenziwa njani
• Yintoni i-TSH ethe-ethe ethe
• Xa kuhlolwa i-TSH

Uvavanyo lwe-TSH lusebenza ukuvavanya ukusebenza kwe-thyroid kwaye luhlala lucelwa ngugqirha oqhelekileyo okanye ugqirha we-endocrinologist, ukuvavanya ukuba ingaba le ndlala isebenza ngokufanelekileyo, kwaye kwimeko ye-hypothyroidism, hyperthyroidism, okanye kwimeko yomhlaza owahlukileyo we-thyroid, i-follicular okanye i-papillary, umzekelo.

Ihomoni ye-Thyostimulating (TSH) iveliswa yi-pituitary gland kwaye injongo yayo kukukhuthaza i-thyroid ukuvelisa i-hormone T3 kunye ne-T4. Xa amaxabiso e-TSH enyuka egazini, oko kuthetha ukuba uxinzelelo lwe-T3 kunye ne-T4 egazini lisezantsi. Xa ifunyenwe kumanqanaba asezantsi, i-T3 kunye ne-T4 zikhona kwindawo ephezulu egazini. Jonga ukuba zeziphi iimvavanyo ezibalulekileyo zokuvavanya idlala lengqula.

Amaxabiso esalathiso

Ixabiso lereferensi ye-TSH iyahluka ngokobudala bomntu kunye naselebhu apho kwenziwa khona uvavanyo, kwaye zihlala zi:

Zingathetha ntoni iziphumo

I-TSH ephezulu

• IHypothyroidism: Uninzi lwexesha i-TSH ephezulu ibonisa ukuba i-thyroid ayivelisi i-hormone eyaneleyo, kwaye ngoko i-pituitary gland izama ukuhlawulela oku ngokunyusa amanqanaba e-TSH egazini ukuze i-thyroid iqhube kakuhle. Olunye lweempawu ze-hypothyroidism yi-TSH ephezulu kunye ne-T4 esezantsi, kwaye inokubonisa i-subclinical hypothyroidism xa i-TSH iphezulu, kodwa i-T4 ikuluhlu oluqhelekileyo. Fumanisa ukuba yintoni i-T4.
• Amayeza: Ukusetyenziswa kweedosi ezisezantsi zamachiza ngokuchasene ne-hypothyroidism okanye ezinye iziyobisi, ezinje ngePropranolol, Furosemide, Lithium kunye namayeza ane-iodine, kunokunyusa uxinzelelo lwe-TSH egazini.
• Ithumba lelungu lobufazi inokubangela ukwanda kwe-TSH.

Iimpawu ezinxulumene ne-TSH ephezulu ziqhelekile kwi-hypothyroidism, njengokudinwa, ukutyeba, ukuqhina, ukuziva ubanda, ukunyuka kweenwele zobuso, ubunzima bokujonga, ulusu olomileyo, iinwele kunye neenzipho ezibuthathaka. Funda ngakumbi malunga ne-hypothyroidism.

I-TSH ephantsi

• Hyperthyroidism: I-TSH esezantsi ihlala ibonisa ukuba i-thyroid ivelisa i-T3 kunye ne-T4 ngokugqithileyo, isonyusa la maxabiso, kwaye ngenxa yoko incindi yebhinqa inciphisa ukukhutshwa kwe-TSH ukuzama ukulawula ukusebenza kwe-thyroid. Qonda ukuba yintoni i-T3.
• Ukusetyenziswa kwamayeza: Xa idosi yesidakamizwa se-hypothyroid iphezulu kakhulu, amaxabiso e-TSH angaphantsi kokufanelekileyo. Olunye unyango olunokubangela i-TSH esezantsi zezi: ASA, corticosteroids, dopaminergic agonists, fenclofenac, heparin, metformin, nifedipine okanye pyridoxine, umzekelo.
• Ithumba lelungu lobufazi ingakhokelela kwi-TSH ephantsi.

Iimpawu ezinxulumene ne-TSH esezantsi ziqhelekile kwi-hyperthyroidism, njengokuphazamiseka, ukubetha kwentliziyo, ukuqaqanjelwa sisisu, ukwehla kobunzima, ukoyika, ukungcangcazela kunye nokuncipha kwemisipha. Kule meko, kuyinto eqhelekileyo ukuba i-TSH ibe sezantsi kwaye i-T4 ibe phezulu, kodwa ukuba i-T4 isephakathi kwe-01 ne-04 μUI / mL, oku kungabonisa i-subclinical hyperthyroidism. I-TSH esezantsi kunye ne-T4 esezantsi, inokubonisa i-anorexia nervosa, umzekelo, kodwa nakweyiphi na imeko ukuxilongwa kwenziwa ngugqirha oyalele uvavanyo. Funda ngakumbi malunga nonyango lwe-hyperthyroidism.

Uviwo lwenziwa njani

Uvavanyo lwe-TSH lwenziwa kwisampulu yegazi encinci, ekufuneka iqokelelwe ngokuzila ukutya ubuncinci iiyure ezi-4. Igazi eliqokelelweyo lithunyelwa elebhu ukuba lihlolwe.

Elona xesha lilungileyo lokwenza olu vavanyo kusasa, njengoko uxinzelelo lwe-TSH egazini luyehluka ngalo lonke usuku. Ngaphambi kokwenza uviwo, kubalulekile ukubonisa ukusetyenziswa kwamanye amayeza, ngakumbi amayeza e-thyroid, njenge-Levothyroxine, njengoko inokuphazamisa iziphumo zoviwo.

Yintoni i-TSH ethe-ethe ethe

Uvavanyo lwe-TSH olubucayi luyindlela ehambele phambili yokuqonda isifo enokufumana isixa esincinci se-TSH egazini uvavanyo oluqhelekileyo olungenakukwazi ukuluchonga. Indlela yokuqonda isifo esetyenziswe kwiilabhoratri inobuzaza kwaye icacile, kwaye uvavanyo lwe-TSH olunobuzaza luqhele ukusetyenziswa kwinkqubo yesiqhelo.

Xa kuhlolwa i-TSH

Uvavanyo lwe-TSH lunoku-odolwa kubantu abasempilweni, ukuvavanya nje ukusebenza kwe-thyroid, kwaye kwimeko ye-hyperthyroidism, hypothyroidism, Hashimoto's thyroiditis, ukukhulisa i-thyroid, ubukho besifo se-thyroid esibuhlungu okanye esibi, ngexesha lokukhulelwa, kunye nokubeka iliso kumthamo wokutshintshwa kwe-thyroid. iziyobisi, kwimeko yokurhoxa kweli dlala.

Ngokwesiqhelo, olu vavanyo luyacelwa kubo bonke abantu abangaphezulu kweminyaka engama-40 ubudala, nokuba azikho iimeko zesifo se-thyroid kusapho.