Ukuhanjiswa kwe-Fecal: Isisitshixo ekuphuculeni impilo ye-Gut?

Umxholo

• Yintoni ukufakelwa okungafunekiyo?
• Kwenziwa njani?
• Colonoscopy
• Enema
• Ityhubhu yeNasogastric
• Njengezingxobo
• Ngaba ibangela naziphi na iziphumo ebezingalindelekanga?
• Ivela phi isitulo?
• Zithini izibonelelo zokunyanga uC.
• Kuthekani ngezibonelelo zezinye iimeko?
• Isifo sengqondo sesifo esibuhlungu (IBS)
• Ukudumba okwenziwa sisilonda sikabhobhosi (UC)
• Ingxaki yesifo sengqondo (ASD)
• Ukuhla ukusinda
• Ngubani ongafanelanga ukufakelwa ilindle?
• Yintoni ukuma kwe-FDA?
• Kuthiwani ngokufakelwa kwe-fecal fecal?
• Umgca wezantsi

Yintoni ukufakelwa okungafunekiyo?

Ukufakelwa okungcolileyo yinkqubo ehambisa isitulo ukusuka kumnikeli iye kwithumbu lesisu (GI) somnye umntu ngenjongo yokunyanga isifo okanye imeko. Ikwabizwa ngokuba yi-fecal microbiota transplant (FMT) okanye i-bacteriotherapy.

Ziyanda ngokuya zisanda njengoko abantu besiya beqhelana nokubaluleka kwe-gut microbiome. Uluvo emva kokufakelwa ilindle kukuba banceda ukungenisa iibhaktheriya eziluncedo ngakumbi kwi-GI tract yakho.

Kananjalo, ezi bhaktiriya ziluncedo zinokunceda ngokuchasene noluhlu lweemeko zempilo, ukusuka kusulelo lwe-GI ukuya kwi-autism spectrum disorder (ASD).

Kwenziwa njani?

Zininzi iindlela zokwenza utyando lwelindle, nganye inezibonelelo zazo.

Colonoscopy

Le ndlela ihambisa ulungiselelo lwesitulo samanzi ngqo emathunjini akho amakhulu ngokusebenzisa ikholososcopy. Rhoqo, ityhubhu yekolonoscopy inyanzeliswa iphelele emathunjini akho amakhulu. Njengoko ityhubhu irhoxa, ifaka ukufakelwa emathunjini akho.

Ukusetyenziswa kwe-colonoscopy kunenzuzo yokuvumela oogqirha ukuba babone ngeso lengqondo indawo yamathumbu akho amakhulu anokonakaliswa ngenxa yemeko engaphantsi.

Enema

Njengendlela yekolonoscopy, le ndlela yazisa ukufakelwa ngokuthe ngqo emathunjini akho amakhulu ngokusebenzisa i-enema.

Unokucelwa ukuba ulale ngecala ngelixa umzimba wakho osezantsi uphakanyisiwe. Oku kwenza ukuba kube lula ukufakelwa ukufikelela emathunjini akho. Emva koko, incam ye-enema ethanjisiweyo ifakwa ngobunono kwi-rectum yakho. Ukufakelwa kwakhona, okusengxoweni ye-enema, emva koko kuvunyelwe ukuba kuye kungena kwi-rectum.

Ukutshintshwa kwe-Fecal okunikezwe yi-enema kuhlala kungangenisi kwaye kunciphisa iindleko kuneekolonoscopies.

Ityhubhu yeNasogastric

Kule nkqubo, ulungiselelo lwesitulo samanzi sihanjiswa kwisisu sakho ngombhobho ohamba ngeempumlo. Ukusuka esiswini sakho, esi sixhobo emva koko siye emathunjini akho.

Okokuqala, uya kunikwa ichiza lokumisa isisu sakho ekuveliseni i-asidi enokubulala izinto eziluncedo kulungiselelo lokufakelwa.

Emva koko, ityhubhu ifakwe kwimpumlo yakho. Ngaphambi kwenkqubo, ingcali yezempilo iya kujonga ukubekwa kwetyhubhu isebenzisa itekhnoloji yokucinga. Nje ukuba ibekwe ngokuchanekileyo, baya kusebenzisa isirinji ukucoca ulungiselelo ngetyhubhu nakwisisu sakho.

Njengezingxobo

Le yeyona ndlela intsha yokufakelwa ilindle ebandakanya ukuginya inani leepilisi ezinokulungiselela isitulo. Xa kuthelekiswa nezinye iindlela, yeyona nto incinci ingenayo kwaye inokwenziwa kwiofisi yezonyango okanye nasekhaya.

Ngo-2017 uthelekise le ndlela kwi-colonoscopy kubantu abadala ephindayo IClostridium difficile usulelo. I-capsule ayibonakali ingasebenzi kakuhle kune-colonoscopy ngokubhekisele kuthintelo losulelo oluphindaphindiweyo ubuncinci iiveki ezili-12.

Okwangoku, le ndlela yokuginya njengezingxobo ifuna ukuqhubeka kokufunda ukuze uyiqonde ngokupheleleyo ukusebenza kwayo kunye nokhuseleko.

Ngaba ibangela naziphi na iziphumo ebezingalindelekanga?

Ukulandela ukufakelwa kwe-fecal, unokufumana iziphumo ezimbalwa, kubandakanya:

• ukungaphatheki kakuhle esiswini okanye ukubamba
• ukuqhina
• ukudumba
• urhudo
• ukubhinqa okanye ukunyanzelisa

Nxibelelana nomboneleli wakho wezempilo kwangoko ukuba iintlungu ziba nzima okanye amava akho:

• ukudumba okukhulu kwesisu
• ukugabha
• igazi kwisitulo sakho

Ivela phi isitulo?

Isitulo esisetyenziselwa ukufakela ilindle sivela kubaxhasi babantu abasempilweni. Kuxhomekeka kwinkqubo, isitulo sinokwenziwa kwisisombululo eselulwelo okanye somiswe kwinto yegreyini.

Abo banokunikela kufuneka benze iimvavanyo ezahlukeneyo, kubandakanya:

• iimvavanyo zegazi ukujonga i-hepatitis, i-HIV kunye nezinye iimeko
• Uvavanyo lwelindle kunye neenkcubeko ukujonga iiparasites kunye neminye imiqondiso yemeko engaphantsi

Abaxhasi nabo bahamba ngenkqubo yokujonga ukuba ngaba:

• bathathe amayeza okubulala iintsholongwane kwezi nyanga zintandathu zidlulileyo
• banamajoni omzimba abuthathaka
• Unembali yokuziphatha emngciphekweni ngokwesondo, kubandakanya neentlobano zesini ngaphandle kokhuseleko lomqobo
• Ndifumene umvambo okanye ukugqobhoza umzimba kwiinyanga ezintandathu ezidlulileyo
• ndinembali yokusebenzisa iziyobisi
• Kutshanje baye kumazwe anezinga eliphezulu losulelo lwezifo
• unesifo esinganyangekiyo se-GI, esifana nesifo sokudumba

Unokufumana iiwebhsayithi ezihambisa iisampuli zelindle ngeposi. Ukuba ucinga ngokufakelwa ilindle, qiniseka ukuba usebenza nomboneleli wakho wezempilo ukuqinisekisa ukuba ufumana isampulu kumnikeli ofanelekileyo.

Zithini izibonelelo zokunyanga uC.

C. eyahlukileyoUsulelo luyaziwa ngokuba nzima ukunyanga. Malunga nabantu abanyangwe ngamayeza okubulala iintsholongwane C. eyahlukileyo Usulelo luya kuqhubeka nokuphuhlisa usulelo oluqhubekayo. Kwaye ukunganyangeki kwi-antibiotic in C. eyahlukileyo ibisanda.

C. eyahlukileyo usulelo lwenzeka xa kukho ukugqitha kwebhaktheriya kwindlela yakho ye-GI. Ngokutsho kweKholeji yaseMelika yeGastroenterology, iipesenti ezi-5 ukuya kwezi-15 zabantu abadala abasempilweni- kunye neepesenti ezingama-84.4 zabantwana abasandul 'ukuzalwa kunye neentsana ezisempilweni- banexabiso eliqhelekileyo C. eyahlukileyo emathunjini abo. Ayibangeli ngxaki kwaye iyanceda ekugcineni ubungakanani bebacteria emathunjini.

Nangona kunjalo, ezinye iibhaktheriya emathunjini akho zihlala zigcina abantu C. eyahlukileyo Ukujonga, ukuyikhusela ekubangeleni usulelo. Ukufakelwa kwe-fecal kunokunceda ukuphinda uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphinde uphumelele C. eyahlukileyo.

Uninzi lwezifundo esele zikho malunga nokusetyenziswa kokufakelwa ilindle kunyango lwe C. eyahlukileyo izifo zincinci. Nangona kunjalo, uninzi luvelise iziphumo ezifanayo ezibonisa inqanaba lokunyanga elingaphezulu.

Kuthekani ngezibonelelo zezinye iimeko?

Iingcali zisandula ukuphanda ukuba ukufakelwa kwe-fecal kunganceda njani kwezinye iimeko kunye nemicimbi yezempilo, kubandakanya nezinye iimeko ze-GI. Apha ngezantsi kukho umfanekiso ocacileyo wolunye uphando ukuza kuthi ga ngoku.

Ngelixa ezinye zezi ziphumo zithembisa, kusekho isidingo esikhulu sophando oluthe kratya kule ndawo ukumisela ukusebenza kunye nokukhuseleka kokuthuthwa kwendle kwezi zinto zisetyenziswayo.

Isifo sengqondo sesifo esibuhlungu (IBS)

Olunye uphononongo lwamva nje lwezifundo ezisithoba zafumanisa ukuba ukufakelwa kwe-fecal kuphuculwe iimpawu ze-IBS kubathathi-nxaxheba. Nangona kunjalo, izifundo ezisithoba zazahluke kakhulu kwiikhrayitheriya, ulwakhiwo kunye nohlalutyo.

Ukudumba okwenziwa sisilonda sikabhobhosi (UC)

Izilingo ezine bezithelekisa amaxabiso okuxolelwa e-UC kubantu abafumene ukufakelwa okungafunekiyo kuthelekiswa ne-placebo. Abo bafumana ukufakelwa okungafunekiyo babenenqanaba lokuxolelwa leepesenti ezingama-25, xa kuthelekiswa neepesenti ezintlanu kwabo bakwiqela le-placebo.

Gcina ukhumbula ukuba uxolelo lubhekisa kwixesha elingenazo iimpawu. Abantu abane-UC abaxolelwayo banokuqhubeka nokufumana ikamva okanye iimpawu zangomso.

Ingxaki yesifo sengqondo (ASD)

Into encinci ifumanise ukuba irejimeni eyandisiweyo yokuhanjiswa kokungcola okuhlala iiveki ezisixhenxe ukuya kwezisibhozo yehlisa iimpawu zokwetyisa kubantwana abane-ASD. Iimpawu zokuziphatha kwe-ASD zibonakala ziphucuka ngokunjalo.

Olu phuculo lwabonwa kwiiveki ezisibhozo emva konyango.

Ukuhla ukusinda

Kutshanje kwiimpuku kubandakanyeka amaqela amabini: omnye wondla ukutya okunamafutha aphezulu kwaye omnye wondla ukutya okunamafutha aqhelekileyo kwaye wabekwa kwirejimeni yomthambo.

Iimpuku ekutyeni okunamafutha aphezulu zifumene ukufakelwa kwendle kwiimpuku kwiqela lesibini. Oku kubonakala ukunciphisa ukudumba kunye nokuphucula imetabolism. Bade bachonga iintsholongwane ezininzi ezinxulumene nezi ziphumo, nangona kungacacanga ukuba ezi ziphumo ziya kuguqulela njani ebantwini.

Funda ngakumbi malunga nekhonkco phakathi kobunzima kunye ne-gut gut bacteria.

Ngubani ongafanelanga ukufakelwa ilindle?

Ukufakelwa kwe-Fecal akukhuthazwa kubantu abangenakunyanzeliswa ngenxa yokuba:

• amayeza athintela amajoni omzimba
• Intsholongwane kaGawulayo
• isifo sesibindi esiqhubele phambili, njenge-cirrhosis
• kutshintsho lomongo wethambo

Yintoni ukuma kwe-FDA?

Ngelixa uphando olujikeleze ukufakelwa kwendle luyathembisa, uLawulo lokutya kunye noLawulo lweziyobisi (i-FDA) alubamkelanga kulo naluphi na usetyenziso lweklinikhi kwaye lubajonga njengesiyobisi sophando.

Ekuqaleni, oogqirha abafuna ukusebenzisa utyando lwelindle kwakufuneka bafake isicelo kwi-FDA ngaphambi kokwenza inkqubo. Oku kubandakanya inkqubo ende yokuvunywa eyatyhafisa abaninzi ekusebenziseni ukufakelwa kwendle.

I-FDA iyikhulule le mfuno yokufakela ilindle ekujongeni ukunyanga okuphindayo C. eyahlukileyo usulelo olungaphendulanga kwii-antibiotics. Kodwa oogqirha basadinga ukufaka isicelo kulo naluphi na usetyenziso ngaphandle kwale meko.

Kuthiwani ngokufakelwa kwe-fecal fecal?

I-intanethi igcwele malunga nokwenza utyando lwe-fecal ekhaya. Kwaye ngelixa indlela ye-DIY isenokuvakala njengeyona ndlela ilungileyo yokujikeleza imigaqo ye-FDA, ngokubanzi ayisiyombono ilungileyo leyo.

Nazi izizathu ezimbalwa zokuba kutheni:

• Ngaphandle kokuvavanywa kwabanikeli abafanelekileyo, unokuba uzibeka emngciphekweni wokufumana isifo.
• Oogqirha abenza utyando lwelindle banoqeqesho olubanzi kwindlela yokwenza ngokukhuselekileyo amalungiselelo okutshintshela.
• Uphando kwiziphumo zexesha elide kunye nokhuseleko lokumiliselwa kwilindle lusasikelwe umda, ngakumbi iimeko ezingezizo C. eyahlukileyo usulelo.

Umgca wezantsi

Ukufakelwa kwe-Fecal kukunyanga okunokubakho kunyango lweemeko ezahlukeneyo. Namhlanje, zisetyenziselwa ezisisiseko ukunyanga okuphindayo C. eyahlukileyo usulelo.

Njengoko iingcali zifunda ngakumbi malunga nokuhanjiswa kwendle, banokuba lukhetho kwezinye iimeko, ukusukela kwimiba ye-GI ukuya kwiimeko ezithile zophuhliso.