I-Acromegaly kunye ne-gigantism: iimpawu, oonobangela kunye nonyango

Umxholo

• Iimpawu eziphambili
• Zithini iingxaki
• Indlela yokuqinisekisa ukuxilongwa
• Unyango lwenziwa njani

I-Gigantism sisifo esinqabileyo apho umzimba uvelisa ukukhula okugqithileyo kwihomoni, edla ngokubangelwa bubukho besisu esibuhlungu kwi-pituitary gland, eyaziwa ngokuba yi-pituitary adenoma, ebangela ukuba amalungu kunye namalungu omzimba akhule ngakumbi kunesiqhelo.

Xa esi sifo sivela ekuzalweni, siyaziwa ngokuba yi-gigantism, nangona kunjalo, ukuba isifo sivela ebudaleni, ngesiqhelo sijikeleza iminyaka engama-30 okanye engama-50, saziwa ngokuba yi-acromegaly.

Kuzo zombini iimeko, esi sifo sibangelwa kukutshintsha kwedlala yebhinqa, indawo yengqondo evelisa ukukhula kwehomoni, kwaye ke unyango lwenziwa ukunciphisa imveliso yehomoni, enokwenziwa ngokuhlinzwa., Ukusetyenziswa kwamayeza okanye imitha, umzekelo.

Iimpawu eziphambili

Abantu abadala abane-acromegaly okanye abantwana abane-gigantism bahlala bezikhulu kunezandla eziqhelekileyo, iinyawo kunye nemilebe, kunye neempawu zobuso ezibi. Ukongeza, ukukhula okungaphezulu kwehomoni kunokubangela:

• Ukulinganisa okanye ukutshisa ezandleni nasezinyaweni;
• Ukugqithisa kweglucose egazini;
• Uxinzelelo oluphezulu;
• Iintlungu kunye nokudumba kumalungu;
• Umbono kabini;
• Imandible eyandisiweyo;
• Guqula kwi-locomotion;
• Ukukhula kolwimi;
• Ukufikisa emva kwexesha;
• Imijikelezo yokuya exesheni ngokungaqhelekanga;
• Ukudinwa okugqithisileyo.

Ukongeza, njengoko kukho amathuba okuba ukukhula okungaphezulu kwehomoni kuveliswa yithumba elibi kwi-pituitary gland, ezinye iimpawu ezinjengeentloko eziqhelekileyo, iingxaki zombono okanye ukwehla komnqweno wesini, umzekelo, kunokuvela.

Zithini iingxaki

Ezinye zeengxaki ezinokuzisa isigulana kwezi zilandelayo:

• Isifo seswekile;
• Ukulala;
• Ukuphulukana nombono;
• Ukwanda kobukhulu bentliziyo;

Ngenxa yomngcipheko wezi ngxaki, kubalulekile ukuba uye kugqirha xa usirhanela esi sifo okanye utshintsho olwenzekayo.

Indlela yokuqinisekisa ukuxilongwa

Xa kukho urhano lokuba ne-gigantism, kufuneka kwenziwe uvavanyo lwegazi ukuvavanya amanqanaba e-IGF-1, iprotein eyonyukayo xa amanqanaba okukhula kwehomoni nawo engaphezulu kwesiqhelo, ebonisa i-acromegaly okanye i-gigantism.

Emva koviwo, ngakumbi kwimeko yomntu omdala, iskena se-CT sinokuyalelwa, umzekelo, ukuchonga ukuba ngaba kukho ithumba kwilungu lengqula elinokuthi litshintshe ukusebenza kwalo. Kwiimeko ezithile, ugqirha unoku-odola umlinganiso wokukhula kwe-hormone.

Unyango lwenziwa njani

Unyango lwe-gigantism luyehluka ngokwento ebangela ukukhula okungaphezulu kwehomoni. Ke, ukuba kukho ithumba kwidlala lepituitary, kuhlala kucetyiswa ukuba kwenziwe utyando ukuze kususwe eli thumba kwaye kubuyiswe imveliso eyiyo yamadlala.

Nangona kunjalo, ukuba akukho sizathu sokuba umsebenzi we-pituitary utshintshe okanye ukuba utyando alusebenzi, ugqirha unokubonisa kuphela ukusetyenziswa kwemitha okanye amayeza, afana ne-somatostatin analogs okanye i-dopamine agonists, umzekelo, ekufuneka isetyenziswe ngexesha lobomi bonke ukugcina amanqanaba ehomoni phantsi kolawulo.