Izizathu zeGout

Umxholo

• Ukwehla kokukhutshwa kwe-uric acid
• Ukwanda kwemveliso yeuric acid
• Ukutya okuphezulu kwi-purines
• Imiba yomngcipheko
• Ubudala kunye nesini
• Imbali yosapho
• Amayeza
• Ukusetyenziswa kotywala
• Ukuvezwa kwelothe
• Ezinye iimeko zempilo
• Izinto ezibangela igawuthi
• Imbonakalo

Ushwankathelo

Igawuthi ibangelwa kukwenziwa kweekristale zomchamo kwizicubu zomzimba. Ihlala yenzeka kumalungu ajikelezileyo kunye neziphumo zohlobo olubuhlungu lwesifo samathambo.

Iikristale ze-urate ezifakwa kwizicwili xa kukho i-uric acid eninzi egazini. Le khemikhali yenziwa xa umzimba wophula izinto ezaziwa ngokuba ziipurines. Iuric acid eninzi egazini ikwabizwa ngokuba yi-hyperuricemia.

Igawuthi inokubangelwa kukuncipha kokukhutshwa kwe-uric acid, ukwanda kwemveliso ye-uric acid, okanye ukutya okuphezulu kwe-purines.

Ukwehla kokukhutshwa kwe-uric acid

Ukwehla kokukhutshwa kwe-uric acid sesona sizathu sixhaphakileyo segawuthi. IUric acid ihlala isuswa emzimbeni wakho zizintso zakho. Xa oku kungenzeki ngokufanelekileyo, inqanaba lakho le-uric acid liyanda.

Unobangela unokuba lilifa, okanye unokuba neengxaki zezintso ezikwenza ungabinako ukususa iuric acid.

Ityhefu yelothe kunye nezinye iziyobisi, ezinje nge-diuretics kunye ne-immunosuppressant drug, zinokubangela ukonzakala kwezintso okungakhokelela ekugcinweni kwe-uric acid. Isifo seswekile esingalawulwayo kunye noxinzelelo lwegazi kunokunciphisa ukusebenza kwezintso.

Ukwanda kwemveliso yeuric acid

Ukunyuka kwemveliso ye-uric acid kunokubangela nokuba igout. Kwiimeko ezininzi, unobangela wokunyuka kwemveliso ye-uric acid ayaziwa. Ingabangelwa kukungaqheleki kwe-enzyme kwaye inokwenzeka kwiimeko kubandakanya:

• lymphoma
• Ileukemia
• i-hemolytic anemia
• Psoriasis

Inokwenzeka kwakhona njengempembelelo esecaleni yechemotherapy okanye unyango ngemitha, ngenxa yokungaqhelekanga kwilifa, okanye ngenxa yokutyeba kakhulu.

Ukutya okuphezulu kwi-purines

I-Purines yimichiza yendalo ye-DNA kunye ne-RNA. Xa umzimba wakho uwaqhekeza, ajika abe yiuric acid. Ezinye i-purines zifumaneka ngokwendalo emzimbeni. Nangona kunjalo, ukutya okuphezulu kwi-purines kunokukhokelela kwi-gout.

Okunye ukutya kuphezulu kakhulu kwi-purines kwaye kunokuphakamisa amanqanaba e-uric acid egazini. Ukutya okuphezulu kwe-purine kubandakanya:

• inyama, njengezintso, isibindi, kunye nesonka esimnandi
• inyama ebomvu
• iintlanzi ezinamafutha, ezifana nesardadi, ii-anchovies kunye neherring
• imifuno ethile, kubandakanya i-asparagus kunye nekholifulawa
• iimbotyi
• amakhowa

Imiba yomngcipheko

Kwiimeko ezininzi, oyena nobangela we-gout okanye i-hyperuricemia akwaziwa. Oogqirha bakholelwa ukuba kusenokwenzeka ngenxa yendibaniselwano yelifa, ihomoni, okanye ukutya. Kwezinye iimeko, unyango lweziyobisi okanye iimeko ezithile zonyango zinokubangela neempawu zokugula.

Ubudala kunye nesini

Amadoda kunokwenzeka ngakumbi kunabafazi ukuba neempawu zesifo. Uninzi lwamadoda lufunyaniswa phakathi kweminyaka engama-30 ukuya kwengama-50 ubudala. Kwabasetyhini, esi sifo sixhaphake kakhulu emva kokuyeka ukuya exesheni.

Igawuthi inqabile ebantwaneni nakubantu abadala abancinci.

Imbali yosapho

Abantu abanezihlobo zegazi abane-gout kunokwenzeka ukuba bafumane le meko ngokwabo.

Amayeza

Kukho amayeza aliqela anokunyusa umngcipheko wokugula. Oku kubandakanya:

• I-aspirin yedosi ephantsi yemihla ngemihla. I-aspirin yedosi ephantsi isetyenziselwa ukuthintela ukubetha kwentliziyo kunye nokubetha.
• I-Thiazide yomchamo. La mayeza asetyenziselwa ukunyanga uxinzelelo lwegazi, ukungaphumeleli kwentliziyo (CHF), kunye nezinye iimeko.
• Iziyobisi ze-Immunosuppressant. Amachiza e-immunosuppressant, anje nge-cyclosporine (Neoral, Sandimmune), athathwa emva kokufakelwa komzimba kunye neemeko ezithile ze-rheumatologic.
• ILevodopa (iSinemet). Olu lonyango olukhethiweyo kubantu abanesifo sikaParkinson.
• Niacin. Eyaziwa nangokuthi i-vitamin B-3, i-niacin isetyenziselwa ukwandisa i-lipoproteins (HDL) egazini.

Ukusetyenziswa kotywala

Ukumodareyitha ukuya ekuseleni kakhulu kwandisa umngcipheko wokugula. Oku kuhlala kuthetha ukusela ngaphezulu kwesibini ngemini kuninzi lwamadoda okanye enye ngosuku kubo bonke abantu basetyhini okanye nawaphina amadoda angaphezu kwama-65.

Ngokukodwa ibhiya ibandakanyekile, kwaye isiselo siphezulu kwi-purines. Nangona kunjalo, uphononongo luka-2014 luqinisekisile ukuba iwayini, ibhiya, kunye notywala konke kunokubangela uhlaselo gout oluphindaphindiweyo. Funda ngakumbi malunga nobudlelwane phakathi kotywala kunye ne-gout.

Ukuvezwa kwelothe

Ukubonakaliswa kwinqanaba eliphezulu lokukhokela kukwayanyaniswa negawuthi.

Ezinye iimeko zempilo

Abantu abanezifo kunye neemeko zilandelayo kunokwenzeka ukuba babe ne-gout:

• ukutyeba kakhulu
• isifo seswekile
• igazi elonyukayo
• cholesterol ephezulu
• hypothyroidism
• isifo sezintso
• i-hemolytic anemia
• Psoriasis

Izinto ezibangela igawuthi

Ezinye izinto ezinokubangela uhlaselo lwegawuthi zibandakanya:

• ukulimala ngokudibeneyo
• usulelo
• utyando
• izidlo zengozi
• ukwehlisa ngokukhawuleza amanqanaba e-uric acid ngamayeza
• ukuphelelwa ngamanzi emzimbeni

Imbonakalo

Ungawanciphisa amathuba okuphuhlisa igawuthi ngokujonga indlela otya ngayo kunye nokutya ukutya okuncinci kwii-purines. Ezinye izinto ezibangela igawuthi, ezinjengokonzakala kwezintso okanye imbali yosapho, azinakwenzeka ukuba ziphikiswe.

Thetha nogqirha wakho ukuba unomdla malunga namathuba akho okuphuhlisa i-gout.

Banokuza nesicwangciso sokunciphisa amathuba akho okuphuhlisa imeko. Umzekelo, ukuba unemingcipheko yokufumana isifo (njengemeko ethile yonyango), banokuthi baqwalasele oko ngaphambi kokucebisa iintlobo ezithile zamachiza.

Nangona kunjalo, ukuba uyayiphuhlisa i-gout, qiniseka ukuba imeko inokulawulwa ngokudityaniswa kwamayeza, utshintsho kwindlela otya ngayo, kunye nolunye unyango.