Yintoni i-Wegener granulomatosis kunye nendlela yokuyinyanga

Umxholo

• Iimpawu eziphambili
• Unyango njani
• Uxilongo lwenziwa njani
• Yintoni ebangela i-Wegener granulomatosis

I-Wegener's granulomatosis, ekwabizwa ngokuba yi-granulomatosis kunye ne-polyangiitis, sisifo esinqabileyo nesiqhubela phambili esibangela ukuvuvukala kwimithambo yegazi kwiindawo ezahlukeneyo zomzimba, kubangele iimpawu ezinjengokuxinana komoya, ukuphefumla kancinci, izilonda zolusu, ukuphuma kweempumlo, ukudumba ezindlebeni, umkhuhlane , ukuqaqanjelwa ngumzimba, ukuphelelwa ngumdla wokutya okanye ukucaphuka kwamehlo.

Njengokuba sisifo esibangelwe kukutshintsha komzimba, unyango lwaso lwenziwa ikakhulu ngamayeza okulawula inkqubo ye-inume, enje nge-corticosteroids kunye ne-immunosuppressants, kwaye nangona lungekho unyango, isifo ngokubanzi silawulwa kakuhle, sivumela ubomi obuqhelekileyo.

I-Wegener's granulomatosis yinxalenye yeqela lezifo ezibizwa ngokuba yi-vasculitis, ebonakaliswa kukudumba kunye nokonakala kwimithambo yegazi, enokuthi ithintele ukusebenza kwamalungu ohlukeneyo. Ukuziqonda ngcono iintlobo ze-vasculitis ezikhoyo kunye nendlela yokubachonga.

Iimpawu eziphambili

Ezinye zeempawu eziphambili ezibangelwa sesi sifo zibandakanya:

• Sinusitis kunye neempumlo zeempumlo;
• Ukukhohlela, iintlungu esifubeni kunye nokuphefumla okufutshane;
• Ukubunjwa kwezilonda kwi-mucosa yempumlo, engakhokelela ekukhubazekeni okwaziwayo ngeempumlo ze-saddle;
• Ukudumba ezindlebeni;
• Ukudibana kunye nokunye ukudumba emehlweni;
• Umkhuhlane nobusuku ukubila;
• Ukudinwa nokudinwa;
• Ukuphelelwa ngumdla wokutya kunye nokwehla kobunzima;
• Iintlungu ezidibeneyo kunye nokudumba kumalungu;
• Ubukho begazi kumchamo.

Kwiimeko ezinqabileyo, kunokubakho nokuphazamiseka kwentliziyo, okukhokelela kwi-pericarditis okanye izilonda kwimithambo yegazi, okanye nakwinkqubo yeemvakalelo, ekhokelela kwiimpawu zemithambo-luvo.

Ukongeza, abaguli abanesi sifo banotyekelo olwandileyo lokuphuhlisa i-thrombosis, kwaye ingqalelo kufuneka ihlawulwe kwiimpawu ezibonisa le ngxaki, njengokudumba kunye nokubomvu kwimilenze.

Unyango njani

Unyango lwesi sifo lubandakanya ukusetyenziswa kwamayeza anceda ukulawula amajoni omzimba, anje ngeMethylprednisolone, iPrednisolone, iCyclophosphamide, iMethotrexate, iRituximab okanye ezonyango.

I-antibiotic sulfamethoxazole-trimethoprim inokunxulunyaniswa nonyango njengendlela yokunciphisa ukubuyela umva kwezinye iintlobo zezifo.

Uxilongo lwenziwa njani

Ukuchonga i-Wegener's granulomatosis, ugqirha uya kuvavanya iimpawu ezinikiweyo kunye novavanyo lomzimba, olunokunika imiqondiso yokuqala.

Emva koko, ukuqinisekisa ukuxilongwa, uviwo oluphambili kukwenza i-biopsy yezicubu ezichaphazelekayo, ezibonisa utshintsho oluhambelana ne-vasculitis okanye necrotizing granulomatous inflammation. Iimvavanyo nazo zinoku-odolwa, njengemilinganiselo yomzimba yokuzikhusela ye-ANCA.

Ukongeza, kubalulekile ukuba ugqirha ahlule esi sifo kwabanye esinokubonakalisa ngokufanayo, njengomhlaza wemiphunga, i-lymphoma, ukusetyenziswa kwecocaine okanye i-lymphomatoid granulomatosis, umzekelo.

Yintoni ebangela i-Wegener granulomatosis

Izizathu ezichanekileyo ezikhokelela ekuqalekeni kwesi sifo azaziwa, nangona kunjalo, kuyaziwa ukuba kunxulumene notshintsho ekuphenduleni komzimba, ezinokuba zizinto zomzimba ngokwawo okanye izinto zangaphandle ezingena emzimbeni.