I-insulin-efana ne-Growth Factor (IGF): Into ekufuneka uyazi
Umxholo
- Luphi unxibelelwano phakathi kweswekile kunye ne-IGF?
- Luluphi uvavanyo olukhoyo lwe-IGF?
- Ngaba ungasebenzisa i-IGF ukunyanga isifo seswekile?
- Kuthekani nge-IGF kwizincedisi?
- Yintoni imbono?
Yintoni ukukhula okunje nge-insulin (IGF)?
IGF yincindi yedlala eyenziwa ngumzimba wakho ngokwendalo. Yayisaziwa njenge somatomedin. I-IGF, evela ikakhulu esibindini, isebenza kakhulu njenge-insulin.
I-IGF inceda ukulawula ukukhula kwehomoni kwi-pituitary gland. I-IGF isebenza ngokukhula kwehomoni ukukhuthaza ukukhula kunye nokukhula kwethambo kunye nezicubu. Ezi hormone zichaphazela nendlela umzimba wakho usasaza ngayo iswekile, okanye iswekile. I-IGF kunye ne-insulin banokusebenza kunye ukunciphisa ngokukhawuleza inqanaba leswekile egazini lakho.
Luphi unxibelelwano phakathi kweswekile kunye ne-IGF?
Ukuba unesifo seswekile, umzimba wakho awenzi insulini eyaneleyo okanye awunakusisebenzisa ngokufanelekileyo. Udinga i-insulin ukuze uqhubekise iswekile yamandla. I-insulin inceda ukuhambisa iglucose kwiiseli kuwo wonke umzimba wakho ngelixa unciphisa iswekile egazini lakho.
Luluphi uvavanyo olukhoyo lwe-IGF?
Uvavanyo lwegazi olulula lunokumisela ukuba ingakanani i-IGF onayo egazini lakho.
Oogqirha banokuyalela olu vavanyo xa umntwana engakhuli okanye ekhula njengoko kulindelwe ubudala babo.
Kubantu abadala, olu vavanyo kunokwenzeka ukuba lwenziwe ukukhangela ukuphazamiseka kwamadlala esifuba okanye izilonda. Ayinikwa rhoqo kubantu abanesifo seswekile.
I-IGF ilinganiswa kwii-nanograms ngeemililitha (ng / mL). Uluhlu oluqhelekileyo zezi:
- I-182-780 ng / mL yabantu abaneminyaka eyi-16-24
- I-114-492 ng / mL yabantu abaneminyaka eyi-25-39
- I-90-360 ng / mL yabantu abaneminyaka engama-40-54
- I-71-290 ng / mL yabantu abangama-55 nangaphezulu
Ukuba iziphumo zakho zovavanyo zibonisa amanqanaba aphezulu okanye asezantsi kunoluhlu oluqhelekileyo, kunokuba neenkcazo ezininzi, kubandakanya:
- amanqanaba e-thyroid aphantsi, okanye i-hypothyroidism
- isifo sesibindi
- isifo seswekile esingalawulwayo kakuhle
Ukuba amanqanaba akho e-IGF awekho kuluhlu oluqhelekileyo, oko akuthethi ukuba akukho nto iphosakeleyo. Ugqirha wakho uya kuba nakho ukunika inkcazo ngokusekwe kuluhlu olubanzi lolwazi.
Amanqanaba aphezulu e-IGF anokunyusa umngcipheko we-colorectal, ibele, kunye nomhlaza webala le-Prostate, nangona kungekho zifundo zamva nje ziye zajonga olu nxibelelwano. I-insulin esetyenziswa ngabantu ukunyanga uhlobo lwesibini lweswekile inokwandisa umngcipheko wee-cancer.
Ngaba ungasebenzisa i-IGF ukunyanga isifo seswekile?
IMecasermin (iAlexlexx) yinguqulelo engeyiyo ye-IGF. Yinto amayeza kagqirha amayeza asebenzisa ukunyanga ukusilela ukukhula ebantwaneni. Enye yeziphumo ebezingalindelekanga ezinokubakho ze-mecasermin yi-hypoglycemia. Ukuba une-hypoglycemia, oko kuthetha ukuba une-glucose esezantsi.
Uphando lubonisa ukuba i-IGF iyakwazi ukucinezela uhlobo lweswekile 1 kwiimpuku. Kuhlobo lwe-1 yeswekile, amajoni omzimba ayazijika, ahlasele iiseli ze-beta kwi-pancreas ezivelisa i-insulin. I-IGF inokukwazi ukukhusela ekuhlaselweni komzimba.
Olunye uphononongo lubonakalisile ukuba unyango lwe-IGF lunokunceda ekulawuleni isifo seswekile. Ayenzelwanga unyango lwesifo seswekile ngenxa yeziphumo ebezingalindelekanga ezibi, kubandakanya:
- ukudumba luvo optic
- ukujonga kwakhona
- iintlungu zemisipha
- intlungu edibeneyo
Ngelixa uphando oluthembisayo lukhona, ubudlelwane phakathi kwe-IGF kunye neswekile bunzima. Olunye uphando luyimfuneko ngaphambi kokuba oogqirha basebenzise i-IGF ukunyanga esi sifo sinzima.
Kuthekani nge-IGF kwizincedisi?
Iindidi zezongezo zokutya ziqulathe ukukhula kwehomoni, kubandakanya IGF. Iinkampani ziyabakhuthaza ukulwa nokuguga, amandla, kunye nokuphucula amajoni omzimba, phakathi kwamanye amabango.
I-Arhente yokulwa nokuDalwa kwe-US ilumkisa ukuba iimveliso ezithi ziqulathe i-IGF-1 ayinako. Isenokuhlanjululwa okanye imveliso ingaqulatha ezinye izinto ezinokuba yingozi. Abantu banokusebenzisa gwenxa okanye baphathe gadalala i-IGF-1.
Iziphumo ebezingalindelekanga ze-IGF-1 zinokufana nezo ezinye iihomoni zokukhula. Oku kubandakanya ukwanda kwezicubu zomzimba, ezaziwa ngokuba yi-acromegaly, kunye nomonakalo kumalungu, isibindi kunye nentliziyo.
I-IGF-1 inokubangela ukuba amanqanaba eglucose egazini awe. Ukuba unesifo seswekile, okanye nokuba awunaso, kubalulekile ukuba ubuze kugqirha wakho ngaphambi kokuba uthathe izongezo eziqukethe iihomoni zokukhula.
Yintoni imbono?
Uphando lubonisa ukuba i-IGF inokudibaniswa nesifo seswekile, kodwa abantu abaluqondi ngokupheleleyo unxibelelwano. Unokwazi ukunyanga isifo sakho seswekile nge-IGF, kodwa oku kusaluvavanyo.
Thetha nogqirha wakho ngaphambi kokuba uthathe i-IGF okanye ngaphambi kokuzama ezinye izongezo, kwaye ungatshintshi isicwangciso sakho sonyango ngaphandle kokuthetha nogqirha wakho. Isifo seswekile sisifo esinzima, kwaye sinokubangela iingxaki ezininzi ukuba awufumani nyango lwaso.