Uvavanyo lweLactate Dehydrogenase (LDH)

Umxholo

• Yintoni uvavanyo lwe-lactate dehydrogenase (LDH)?
• Isetyenziselwa ntoni?
• Kutheni ndifuna uvavanyo lwe-LDH?
• Yintoni eyenzekayo ngexesha lovavanyo lwe-LDH?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kuvavanyo?
• Zithetha ntoni iziphumo?
• Izalathiso

Yintoni uvavanyo lwe-lactate dehydrogenase (LDH)?

Olu vavanyo lilinganisela inqanaba le-lactate dehydrogenase (LDH), ekwabizwa ngokuba yi-lactic acid dehydrogenase, egazini lakho okanye ngamanye amaxesha kolunye ulwelo lomzimba. I-LDH luhlobo lweprotein, eyaziwa njenge-enzyme. I-LDH idlala indima ebalulekileyo ekwenzeni amandla omzimba wakho. Ifunyanwa phantse kuzo zonke izicwili zomzimba, kubandakanya ezo zisegazini, entliziyweni, kwizintso, engqondweni nasemiphungeni.

Xa ezi zicwili zonakele, zikhupha i-LDH kwigazi okanye kolunye ulwelo lomzimba. Ukuba igazi lakho le-LDH okanye amanqanaba e-fluid aphezulu, oko kunokuthetha ukuba izicwili ezithile emzimbeni wakho zonakaliswe sisifo okanye ukwenzakala.

Amanye amagama: Uvavanyo lwe-LD, i-lactic dehydrogenase, i-lactic acid dehydrogenase

Isetyenziselwa ntoni?

Uvavanyo lwe-LDH luhlala lusetyenziselwa:

• Fumanisa ukuba ingaba wenzakele emzimbeni
• Ukujonga iingxaki ezibangela ukonakala kwethishu. Oku kubandakanya i-anemia, isifo sesibindi, isifo semiphunga, kunye nezinye iintlobo zosulelo.
• Ukubeka iliso kwi-chemotherapy kwiintlobo ezithile zomhlaza. Uvavanyo lunokubonisa ukuba ngaba unyango luyasebenza na.

Kutheni ndifuna uvavanyo lwe-LDH?

Unokulufuna olu vavanyo ukuba ezinye iimvavanyo kunye / okanye iimpawu zakho zibonisa ukuba unokwenzakala kwithishu okanye isifo. Iimpawu ziya kwahluka ngokuxhomekeka kuhlobo lomonakalo onawo emzimbeni.

Unokufuna uvavanyo lwe-LDH ukuba ngoku unyangwa umhlaza.

Yintoni eyenzekayo ngexesha lovavanyo lwe-LDH?

Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.

I-LDH ngamanye amaxesha ilinganiswa kolunye ulwelo lomzimba, kubandakanya ulwelo kwintambo yomqolo, imiphunga, okanye isisu. Ukuba ufumana olu vavanyo, umboneleli wakho wezempilo uya kukunika ulwazi malunga nenkqubo.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Awudingi naluphi na ulungiselelo olukhethekileyo lovavanyo lwegazi lwe-LDH.

Ngaba bukhona ubungozi kuvavanyo?

Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Zithetha ntoni iziphumo?

Amanqanaba aphakamileyo kune-LDH aqhelekileyo athetha ukuba unolunye uhlobo lomonakalo wesifo okanye isifo. Ukuphazamiseka okubangela amanqanaba aphezulu e-LDH kubandakanya:

• Ukunqongophala kwegazi
• Isifo sezintso
• Isifo sesibindi
• Ukulimala kwemisipha
• Ukuhlaselwa yintliziyo
• Ipancreatitis
• Usulelo, kubandakanya i-meningitis, encephalitis, kunye ne-mononucleosis (mono) esosulelayo
• Iindidi ezithile zomhlaza, kubandakanya i-lymphoma kunye neleukemia. Inqanaba eliphezulu kune-LDH eliqhelekileyo linokuthetha ukuba unyango lomhlaza alusebenzi.

Nangona uvavanyo lunokubonisa ukuba unokwenzakala kwithishu okanye isifo, ayibonisi apho ukhoyo umonakalo. Ukuba iziphumo zakho zibonise ngaphezulu kunqanaba eliqhelekileyo le-LDH, umboneleli wakho unokufuna uku-odola iimvavanyo ezingaphezulu ukuze enze isifo. Olunye lolu vavanyo lunokuba luvavanyo lwe-LDH isoenzyme. Uvavanyo lwe-LDH isoenzyme luthatha amanyathelo ngeendlela ezahlukeneyo ze-LDH. Inokunceda umboneleli wakho afumanise malunga nendawo, uhlobo, kunye nobunzima bomonakalo wethishu.

Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho wezempilo.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Izalathiso

1. UHenry BM, uAggarwal G, uWong J, uBenoit S, uVikse J, uPlebani M, uLippi G. Amanqanaba e-Lactate dehydrogenase axela isifo se-coronavirus 2019 (COVID-19) ubunzima kunye nokufa: Uhlalutyo oluhlanganisiweyo. NdinguJ Emerg Med [kwi-Intanethi]. 2020 ngoMeyi 27 [icatshulwe ngowe-2020 Agasti 2]; 38 (9): 1722-1726. Ifumaneka kwi: https://www.ajemjournal.com/article/S0735-6757(20)30436-8/fulltext
2. Impilo yaBantwana kwiNemours [kwi-Intanethi]. UJacksonville (FL): Isiseko seNemours; c1995–2019. Uvavanyo lwegazi: Lactate Dehydrogenase; [icatshulwe ngo-2019 ngoJulayi 1]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://kidshealth.org/en/parents/test-ldh.html
3. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC; Umbutho waseMelika weKhemesti yezonyango; c2001–2019. Ulwelo lweCerebrospinal (CSF); [ihlaziywe ngo-2017 Novemba 30; icatshulwe ngo-2019 ngoJulayi 1]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://labtestsonline.org/glossary/cerebrospinal
4. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC; Umbutho waseMelika weKhemesti yezonyango; c2001–2019. Lactate iDehydrogenase (LD); [ihlaziywe ngo-2018 Dec 20; icatshulwe ngo-2019 ngoJulayi 1]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://labtestsonline.org/tests/lactate-dehydrogenase-ld
5. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC; Umbutho waseMelika weKhemesti yezonyango; c2001–2019. Meningitis kunye ne-Encephalitis; [ihlaziywe ngo-2018 Feb 2; icatshulwe ngo-2019 ngoJulayi 1]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://labtestsonline.org/conditions/meningitis-and-encephalitis
6. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC; Umbutho waseMelika weKhemesti yezonyango; c2001–2019. Uhlalutyo lwePeritoneal Fluid; [ihlaziywe ngo-2019 ngoMeyi 13; icatshulwe ngo-2019 ngoJulayi 1]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://labtestsonline.org/tests/peritoneal-fluid-analysis
7. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC; Umbutho waseMelika weKhemesti yezonyango; c2001–2019. Uhlalutyo lwamanzi amdaka; [ihlaziywe ngo-2019 ngoMeyi 13; icatshulwe ngo-2019 ngoJulayi 1]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://labtestsonline.org/tests/pleural-fluid-analysis
8. Intliziyo kaZwelonke, iMiphunga, kunye neZiko leGazi [kwi-Intanethi]. I-Bethesda (MD): Isebe lezeMpilo laseMelika kunye neeNkonzo zoLuntu; Uvavanyo lwegazi; [icatshulwe ngo-2019 ngoJulayi 1]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.nhlbi.nih.gov/health-topics/blood-tests
9. IYunivesithi yaseRochester Medical Centre [i-Intanethi]. URochester (NY): KwiYunivesithi yaseRochester Medical Centre; c2019. Health Encyclopedia: Lactic Acid Dehydrogenase (Igazi); [icatshulwe ngo-2019 ngoJulayi 1]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=lactic_acid_dehydrogenase_blood
10. Impilo ye-UF: iYunivesithi yaseFlorida yezeMpilo [i-Intanethi]. IGainesville (FL): yeYunivesithi yaseFlorida yezeMpilo; c2019. Uvavanyo lwe-Lactate dehydrogenase: Ubume; [ihlaziywe ngo-2019 ngoJulayi 1; icatshulwe ngo-2019 ngoJulayi 1]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://ufhealth.org/lactate-dehydrogenase-test
11. Ezempilo ze-UW [kwi-Intanethi]. Madison (WI): Izibhedlele zeYunivesithi yaseWisconsin kunye neGunya leKlinikhi; c2019. I-Lactic Acid Dehydrogenase (LDH): Uqwalaselo lweemviwo; [ihlaziywe ngo-2018 Juni 25; icatshulwe ngo-2019 ngoJulayi 1]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.uwhealth.org/health/topic/testdetail/lactic-dehydrogenase-ldh/tv6985.html#tv6986

Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.