I-Medullary Carcinoma yebele

Umxholo

• Ziintoni iimpawu ze-medullary carcinoma yebele?
• Yintoni ebangela i-medullary carcinoma yebele?
• Ziziphi izinto ezinobungozi kwi-medullary carcinoma?
• Zithini iindlela zonyango lwe-medullary carcinoma yebele?
• Ichongwa njani i-medullary carcinoma yebele?
• Yintoni isigxina se-medullary carcinoma yebele?
• Iyintoni imbonakalo ye-medullary carcinoma yebele?

Ushwankathelo

I-Medullary carcinoma yebele luhlobo oluthile lwe-ductal carcinoma. Luhlobo lomhlaza wamabele oqala kwiindlela zobisi. Lo mhlaza webele ubizwa ngokuba ithumba lifana nenxalenye yengqondo eyaziwa ngokuba yi-medulla. IMedullary carcinoma yebele ibonisa uqikelelo lweepesenti ezi-3 ukuya kwezi-5 zawo onke amatyala omhlaza webele.

I-Medullary carcinoma ihlala incinci ukusasazeka kwii-lymph node kwaye iphendule ngakumbi kunyango kuneentlobo eziqhelekileyo zomhlaza wamabele. Ukuyifumana kwinqanaba layo lokuqala kunokuphucula ukuxela kunye nokunciphisa isidingo sonyango olongezelelweyo ngaphandle kokususa i-tumor ngokwayo.

Ziintoni iimpawu ze-medullary carcinoma yebele?

Ngamanye amaxesha i-medullary carcinoma inokubangela iimpawu ezimbalwa. Umfazi unokuthi aqale aqaphele isigaxa esifubeni sakhe. I-Medullary carcinoma yebele ithanda ukwahlula iiseli zomhlaza ngokukhawuleza. Ke ngoko, uninzi lwabasetyhini lunokuchonga ubunzima ebeleni labo obunokuza ngokobungakanani. Isigaxa sithambekele ekubeni sithambe kwaye sibe nenyama, okanye siqine ekuchukumeni kunye nemida echaziweyo. Uninzi lwe-medullary carcinomas lungaphantsi kweesentimitha ezi-2 ngobukhulu.

Abanye abantu basetyhini banokufumana ezinye iimpawu ezinxulumene ne-medullary carcinoma, kubandakanya:

• ukuthamba kwebele
• intlungu
• bomvu
• ukudumba

Ukuba ufumana naziphi na kwezi mpawu, kufuneka ubone ugqirha.

Yintoni ebangela i-medullary carcinoma yebele?

Ngokwesiko, amathumba anomhlaza webele anokuba nefuthe lehomoni. I-Medullary carcinoma yebele, nangona kunjalo, ihlala ingekho kwimpembelelo yehomoni. Endaweni yoko, umntu obhinqileyo ufumana utshintsho kulwakhiwo lwemfuza lweeseli ezisesifubeni sakhe. Oku kubangela ukuba iiseli zikhule ngokungalawulekiyo (umhlaza). Oogqirha abazi ngqo ukuba kutheni ezi nguqu zenzeka okanye zinxulumene njani ne-medullary carcinoma yebele.

Ziziphi izinto ezinobungozi kwi-medullary carcinoma?

Abanye abantu basetyhini abane-genetic mutation eyaziwa ngokuba yi-BRCA-1 gene basemngciphekweni omkhulu wokufunyaniswa ukuba une-medullary carcinoma yebele, ngokuka-Johns Hopkins Medicine. Olu luhlobo luhlala luqhuba kwiintsapho. Ke ngoko, ukuba owasetyhini unembali yomhlaza wamabele kumalungu osapho asondeleyo, usengozini enkulu yesi sifo. Nangona kunjalo, ukuba owasetyhini unale geni, oku akuthethi ukuba uyakufumana i-medullary carcinoma yebele.

Ukuxilongwa kwe-medullary carcinomas kuphakathi kweminyaka engama-45 no-52. Oku kuhlala kuncinci kancinci kunabafazi abafunyaniswe benesifo se-medullary carcinomas, abafunyaniswa beneminyaka engama-55 okanye ngaphezulu.

Zithini iindlela zonyango lwe-medullary carcinoma yebele?

Ugqirha unokuvavanya iindlela ezahlukeneyo zonyango kwi-medullary carcinoma. Baya kuthathela ingqalelo ubungakanani be-tumor, uhlobo lweseli, kwaye ukuba i-tumor isasazeke kwii-lymph nodes ezikufutshane. Kungenxa yokuba amathumba ngokwesiko kunqabile ukuba asasazeke, abanye oogqirha banokucebisa ngokususa ithumba kuphela kwaye bangaqhubeki nolunye unyango. Oku kuyinyani xa ithumba "linyulu medullary" kwaye ineeseli kuphela ezifana ne-medullary carcinoma.

Nangona kunjalo, ugqirha unokucebisa ukuba kususwe ithumba kunye nezinye iintlobo zonyango lomhlaza. Oku kuyinyani xa umhlaza unokuba "neempawu ze-medullary." Oku kuthetha ukuba ezinye iiseli zijongeka njenge-medullary carcinoma apho ezinye zibukeka njenge-ductal cell carcinoma. Ugqirha unokucebisa ngonyango olongezelelweyo ukuba umhlaza usasazekile kwii-lymph node. Olu nyango lunokubandakanya ichemotherapy (amayeza okubulala iiseli ezikhula ngokukhawuleza) okanye imitha.

Amanye amayeza ngokwesiko asetyenziselwa ukunyanga umhlaza wamabele aqhele ukusebenza kakuhle kwi-medullary carcinoma yebele. Oku kubandakanya unyango olunxulumene neehomoni ezinje nge-tamoxifen okanye i-aromatase inhibitors. Uninzi lwee-medullary cancer zinomhlaza "ongaphindaphindwanga kathathu" umhlaza. Oku kuthetha ukuba umhlaza awuphenduli kwihomoni yeprogesterone kunye / okanye i-estrogen okanye enye iprotein eyaziwa ngokuba yiHER2 / neu protein.

Ichongwa njani i-medullary carcinoma yebele?

Ngenxa yokuba i-medullary carcinoma yebele inqabile kakhulu, oogqirha banokuba nobunzima ekuqaleni ekuchongeni uhlobo oluthile lomhlaza. Banokuchonga isilonda sesifuba kwi-mammogram, eluhlobo olukhethekileyo lwe-X-ray imaging esetyenziselwa ukuvavanya isifuba. Isilonda sihlala si setyhula okanye simile okweqanda kwaye asinayo imida echazwe kakuhle. Ugqirha unokuyalela ezinye izifundo zokucinga. Oku kunokubandakanya ukuskena kwe-ultrasound okanye ngemagneti yokujonga ngemifanekiso ngemagneti.

I-Medullary carcinomas yesifuba inokubaluleka ekuchongeni. Ngamanye amaxesha, umntu wasetyhini unokubakho ngakumbi ekuchongeni isifo somhlaza ngokuziva, kunokuba kunokubonwa kwisifundo sokucinga. Ngesi sizathu, kubalulekile ukuba owasetyhini aqhube iimviwo zanyanga zonke zebele, apho eve khona ithishu yebele lakhe kunye nengono yezigaxa.

Ukuba ugqirha uchonga iqhuma ngokuthinta okanye ngokucinga, banokucebisa nge-biopsy yeqhuma. Oku kubandakanya ukususa iiseli okanye isigaqa uqobo kuvavanyo. Ugqirha ogxile ekuvavanyeni iiseli malunga nokungaqhelekanga uyaziwa njenge-pathologist. Ugqirha wezifo uya kuvavanya iiseli phantsi kwemicroscope. Iiseli zomhlaza zeMedullary nazo zihlala zine-p53 yemfuza. Ukuvavanywa kolu tshintsho kunokubolekisa ukufumanisa isifo se-medullary carcinoma, nangona ingezizo zonke iicancer ze-medullary ezine-p53 mutation.

Yintoni isigxina se-medullary carcinoma yebele?

Amaxabiso okusinda kweminyaka emihlanu ye-medullary carcinoma yebele ihlala ikho ukusuka kuma-89 ukuya kuma-95 eepesenti. Oku kuthetha ukuba iminyaka emihlanu emva kokuxilongwa, naphi na ukusuka kuma-89 ukuya kuma-95 eepesenti yabasetyhini abanolu hlobo lomhlaza basaphila.

Iyintoni imbonakalo ye-medullary carcinoma yebele?

I-Medullary carcinoma yebele ithambekele ekuphenduleni ngcono kunyango lomhlaza wamabele kunezinye iintlobo ze-ductal carcinomas. Ngokufunyanwa kwangoko kunye nonyango, ukuxela kwangaphambili kunye namaxabiso okusinda ayathandeka.