Ukhetho lwe-melanoma kunye nomhlaza wemiphunga

Umxholo

• Ixabiso
• Ngubani onokusebenzisa
• Kusetyenziswa kwanjani
• Iziphumo ezingafunekiyo
• Ngubani ongathathi

I-Opdivo lunyango lwe-immunotherapeutic esisetyenziselwa ukunyanga iintlobo ezimbini ezahlukeneyo zesifo se-oncological, i-melanoma, ngumhlaza wolusu onomdla, kunye nomhlaza wemiphunga.

Eli yeza linceda ukomeleza amajoni omzimba, ukuphucula impendulo yomzimba ngokuchasene neeseli zomhlaza, ukubonisa iziphumo ebezingalindelekanga ezimbalwa kuneendlela zonyango zesintu ezinje ngechemotherapy okanye unyango ngemitha.

Into esebenzayo eOpdivo yiNivolumab kwaye iveliswa yiLabhoratri yeBristol-Myers Squibb. Ngokubanzi, eli yeza alidli ngokuthengwa, kuba liyathengwa kwaye lisetyenziswe ezibhedlele ngokwalo, nangona kunjalo linokuthengwa ezikhemesti ezinesalathiso esingqongqo kwezonyango.

Ixabiso

E-Brazil, ixabiso leendleko ze-Opdivo, kwi-avareji, i-4,000 reais ye-40mg / 4ml vial, okanye i-10 lamawaka reais ye-100mg / 10ml vial, enokwahluka ngokwekhemesti eyithengisayo.

Ngubani onokusebenzisa

I-Nivolumab ibonakalisiwe kunyango lomhlaza wemiphunga osele usasazekile kwaye ungakhange unyangwe ngempumelelo ngekhemotherapy. Ukongeza, inokusetyenziselwa ukunyanga i-melanoma kwiimeko apho umhlaza usasazeke ngokubanzi kwaye awusenakususwa ngotyando.

Kusetyenziswa kwanjani

Indlela yokusebenzisa eli yeza kufuneka ichazwe ngugqirha kuxhomekeke kwimeko nganye, uhlobo lomhlaza, ukongeza kubunzima bomzimba womntu ngamnye, kodwa iOpdivo ihlala ilawulwa esibhedlele ngqo emthanjeni, ihlanjululwe ngetyuwa okanye iswekile , kwiiseshoni ezingama-60 ngosuku.

Ngokubanzi, idosi ekucetyiswa ukuba ibe yiyo yi-3 mg yeNivolumab ngokwekhilogram yobunzima bakho, rhoqo kwiiveki ezi-2, ezinokwahluka ngokokubonisa kwezonyango.

Iziphumo ezingafunekiyo

Iziphumo eziphambili ze-Opdivo zibandakanya ukukhohlela okungapheliyo, iintlungu zesifuba, ukuphefumla nzima, urhudo, ilindle eligazi, iintlungu zesisu, ulusu olumthubi okanye amehlo, isicaphucaphu, ukugabha, ukudinwa kakhulu, ukurhawuzelela nokubomvu kolusu, umkhuhlane, intloko ebuhlungu. iintlungu nokungaboni kakuhle.

Naziphi na iimpawu ezitsha eziqwalaselweyo kufuneka zixelwe kugqirha kwaye zibekwe esweni, njengoko impendulo engalunganga kunye neNivolumab inokwenzeka nangaliphi na ixesha ngexesha okanye emva konyango, kwaye abaguli kufuneka babekwe iliso ngokuqhubekayo ngexesha lokusetyenziswa ukunqanda ukukhula kweengxaki ezinokubakho. pneumonitis, colitis, hepatitis okanye nephritis, umzekelo.

Ngubani ongathathi

Eli yeza contraindicated kwiimeko komzimba kumayeza okanye naziphi na izinto ezincedisayo ekuqulunqweni.

Azikho ezinye izinto ezichasene neli chiza ezichazwe yi-ANVISA, nangona kunjalo, kufuneka isetyenziswe ngononophelo kwabasetyhini abakhulelweyo nakwizigulana ezine-pneumonitis, colitis, hepatitis, izifo ze-endocrine, nephritis, iingxaki zezintso okanye i-encephalitis.