Uvavanyo lwePorphyrin

Umxholo

• Zithini iimvavanyo ze-porphyrin?
• Zenzelwe ntoni?
• Kutheni ndifuna uvavanyo lwe porphyrin?
• Kwenzeka ntoni ngexesha lokuvavanywa kweporphyrin?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kuvavanyo lwe-porphyrin?
• Zithetha ntoni iziphumo?
• Ngaba ikhona enye into endifuna ukuyazi malunga ne-porphyrin test?
• Izalathiso

Zithini iimvavanyo ze-porphyrin?

Uvavanyo lwePorphyrin lilinganisa inqanaba le-porphyrins egazini lakho, kumchamo, okanye kwisitulo. Iiporphyrins ziikhemikhali ezinceda ukwenza ihemoglobin, uhlobo lweprotein kwiiseli zakho ezibomvu zegazi. IHemoglobin ithwala ioksijini esuka kwimiphunga yakho iye kumzimba wakho uphela.

Kuqhelekile ukuba ne-porphyrins encinci egazini lakho nakwezinye iziselo zomzimba. Kodwa i-porphyrin eninzi inokuthetha ukuba unohlobo lwe-porphyria. I-Porphyria sisifo esinqabileyo esinokubangela iingxaki zempilo. I-Porphyria ihlala yahlulwe yangamacandelo amabini:

• Iiporphyrias ezintle, ezichaphazela ikakhulu inkqubo yeemvakalelo kwaye zibangele iimpawu zesisu
• Iiporphyrias ezinqamlezileyo, ezibangela iimpawu zolusu xa uvezwe kukukhanya kwelanga

Ezinye iiporphyrias zichaphazela inkqubo yeemvakalelo kunye nolusu.

Amanye amagama: protoporphyrin; protoporphyrin, igazi; protoporhyrin, isitulo; porphyrins, ilindle; uroporphyrin; porphyrins, umchamo; Uvavanyo lweMauzerall-Granick; asidi; ALA; iporphobilinogen; I-PBG; iprotoporphyrin yasimahla ye-erythrocyte; iqhekeza lerythrocyte FEP

Zenzelwe ntoni?

Uvavanyo lwe-Porphyrin lusetyenziselwa ukufumanisa okanye ukubeka esweni i-porphyria.

Kutheni ndifuna uvavanyo lwe porphyrin?

Unokufuna uvavanyo lwe-porphyrin ukuba unempawu ze-porphyria. Kukho iimpawu ezahlukeneyo zeentlobo ezahlukeneyo ze-porphyria.

Iimpawu ze-porphyria ebukhali zibandakanya:

• Intlungu zesisu
• Ukuqunjelwa
• Isicaphucaphu nokugabha
• Umchamo obomvu okanye omdaka
• Ukulinganisa okanye iintlungu ezandleni kunye / okanye ezinyaweni
• Ubuthathaka bemisipha
• Ukudideka
• Ukuba nemibono

Iimpawu ze-porphyria ezinqamlekileyo zibandakanya:

• Ukujonga ngaphezulu kwelanga
• Amadyungudyungu kulusu lubonakaliswe lilanga
• Ubomvu kunye nokudumba kulusu olubonakalisiweyo
• Ukurhawuzelela
• Utshintsho kumbala wesikhumba

Unokufuna uvavanyo lwe-porphyrin ukuba umntu osapho lwakho une-porphyria. Uninzi lweentlobo ze-porphyria zizuzwe njengelifa, oko kuthetha ukuba imeko idlulisiwe ukusuka kumzali kuye emntwaneni.

Kwenzeka ntoni ngexesha lokuvavanywa kweporphyrin?

I-Porphyrins inokuvavanywa egazini, kumchamo, okanye kwisitulo. Ezona ntlobo zixhaphakileyo zovavanyo lwe porphyrin zidweliswe apha ngezantsi.

• Uvavanyo lwegazi
  • Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.
• Isampuli yomchamo weeyure ezingama-24
  • Uya kuqokelela wonke umchamo wakho ngexesha leeyure ezingama-24. Kolu vavanyo, umboneleli wakho wezempilo okanye elebhu uya kukunika isikhongozeli kunye nemiyalelo ethe ngqo ngendlela yokuqokelela iisampulu zakho ekhaya. Qiniseka ukuba ulandela yonke imiyalelo ngononophelo. Olu vavanyo lweesampuli lweeyure ezingama-24 luyasetyenziswa kuba izixa zezinto zomchamo, kubandakanya i-porphyrin, zinokwahluka mihla le. Ukuqokelela iisampulu ezininzi ngosuku kunokunika umfanekiso ochanekileyo womxholo wakho womchamo.
• Uvavanyo lwe-Urine olungalunganga
  • Ungabonelela ngesampulu yakho nangaliphi na ixesha losuku, kungekho malungiselelo akhethekileyo okanye ukuphatha okufunekayo. Olu vavanyo luhlala lwenziwa kwiofisi yomboneleli wezempilo okanye elebhu.
• Uvavanyo lwe-Stool (ekwabizwa ngokuba yi-protoporphyrin kwisitulo)
  • Uya kuqokelela isampulu yendle yakho uyibeke kwisitya esikhethekileyo. Umboneleli wakho wezempilo uya kukunika imiyalelo ngendlela yokulungiselela isampulu yakho kwaye uyithumele kwilebhu.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Awudingi naluphi na ulungiselelo olukhethekileyo lovavanyo lwegazi okanye umchamo.

Ukuvavanya isitulo, unokuyalelwa ukuba ungatyi nyama okanye uthathe nawaphi na amayeza aneasprini iintsuku ezintathu ngaphambi kovavanyo lwakho.

Ngaba bukhona ubungozi kuvavanyo lwe-porphyrin?

Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Akukho bungozi baziwayo kumchamo okanye kwilindle.

Zithetha ntoni iziphumo?

Ukuba amanqanaba aphezulu e-porphyrin afunyanwa kwigazi lakho, umchamo, okanye isitulo, umboneleli wakho wezempilo uya kuthi a-odole iimvavanyo ezingaphezulu zokuqinisekisa isifo kwaye ufumane ukuba loluphi uhlobo lwe-porphyria onayo. Ngelixa lungekho unyango lwe-porphyria, imeko inokulawulwa. Utshintsho kwindlela yokuphila kunye / okanye amayeza anokunceda ukuthintela iimpawu kunye nobunzima besifo. Unyango oluthile luxhomekeke kuhlobo lwe-porphyria onayo. Ukuba unemibuzo malunga neziphumo zakho okanye malunga ne-porphyria, thetha nomboneleli wakho wezempilo.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Ngaba ikhona enye into endifuna ukuyazi malunga ne-porphyrin test?

Ngelixa uninzi lweentlobo ze-porphyria zizuzwe njengelifa, ezinye iintlobo ze-porphyria zinokufunyanwa. I-porphyria efumanekayo inokubangelwa zizinto ezahlukeneyo, kubandakanya ukubonakaliswa kakhulu kukukhokelela, i-HIV, i-hepatitis C, ukusebenzisa kakhulu i-iron, kunye / okanye ukusebenzisa kakhulu utywala.

Izalathiso

1. Isiseko saseMelika sePorphyria [kwi-Intanethi]. IHouston: Isiseko seAmerican Porphyria; c2010–2017. Malunga nePorphyria; [icatshulwe ngo-2019 ngoDisemba 26]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.porphyriafoundation.org/for-patients/about-porphyria
2. Isiseko saseMelika sePorphyria [kwi-Intanethi]. IHouston: Isiseko seAmerican Porphyria; c2010–2017. Porphyrins kunye nePorphyria Diagnosis; [icatshulwe ngo-2019 ngoDisemba 26]; [malunga nezikrini ezi-6]. Ifumaneka kwi: https://www.porphyriafoundation.org/for-patients/about-porphyria/testing-for-porphyria/diagnosis
3. Isiseko saseMelika sePorphyria [kwi-Intanethi]. IHouston: Isiseko seAmerican Porphyria; c2010–2017. Uvavanyo lweLayini yokuqala; [icatshulwe ngo-2019 ngoDisemba 26]; [malunga nezikrini ezi-4]. Ifumaneka kwi: https://www.porphyriafoundation.org/for-patients/about-porphyria/testing-for-porphyria/first-line-tests
4. Isiseko se-Hepatitis B [kwi-Intanethi]. IDoylestown (PA): Hepb.org; c2017. Izifo zeMetabolism [icatshulwe ngo-2017 kaDisemba 20]; [malunga nezikrini ezili-11]. Ifumaneka kwi: http://www.hepb.org/research-and-programs/liver/risk-factors-for-liver-cancer/inherited-metabolic-diseases
5. UHinkle J, uCheever K. Brunner kunye neSuddarth's Handbook yeLebhu kunye noVavanyo lokuChonga. 2nd Ed, Kindle. IPhiladelphia: Impilo yeWolters Kluwer, uLippincott Williams kunye noWilkins; Ngowama-2014. I-Erythrocyte Porphyrins (FEP) eqhekekileyo; iphe. 308.
6. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. Umbutho waseMelika weKhemesti yezonyango; c2001–2017. Iglosari: Isampula yomchamo ngokungahleliwe; [icatshulwe ngo-2017 kaDisemba 20]; [malunga nezikrini ezi-3].Ifumaneka kwi: https://labtestsonline.org/glossary#r
7. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. Umbutho waseMelika weKhemesti yezonyango; c2001–2017. Uvavanyo lwePorphyrin; [uhlaziyiwe ngo-2017 Dec 20; kucatshulwe ngo-2017 Dec 20]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://labtestsonline.org/tests/porphyrin-tests
8. Ikliniki yaseMayo [kwi-Intanethi]. Isiseko seMayo seMfundo yezoNyango noPhando; c1998–2017. I-Porphyria: Iimpawu kunye noonobangela; 2017 Nov 18 [icatshulwe ngowama-2017 kuDisemba 20]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.mayoclinic.org/diseases-conditions/porphyria/symptoms-causes/syc-20356066
9. Ikliniki yaseMayo: Mayo Medical Laboratories [kwi-Intanethi]. Isiseko seMayo seMfundo yezoNyango noPhando; c1995–2017. I-ID yovavanyo: I-FQPPS: I-Porphyrins, ilindle: Ubume; [icatshulwe ngo-2017 kaDisemba 20]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.mayomedicallaboratories.com/test-catalog/Overview/81652
10. Ikliniki yaseMayo: Mayo Medical Laboratories [kwi-Intanethi]. Isiseko seMayo seMfundo yezoNyango noPhando; c1995–2017. I-ID yovavanyo: I-FQPPS: iiPorphyrins, ilindle: isampuli; [icatshulwe ngo-2017 kaDisemba 20]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.mayomedicallaboratories.com/test-catalog/Specimen/81652
11. Umdibaniso wencwadi yomsebenzisi yenguqulo [ye-Intanethi]. I-Kenilworth (NJ): iMerck kunye ne-Co Inc. .; c2017. IPorphyria engapheliyo; [icatshulwe ngo-2017 kaDisemba 20]; [malunga nezikrini ezi-3]. Ifumaneka kwi: http://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/porphyrias/acute-intermittent-porphyria
12. Umdibaniso wencwadi yomsebenzisi yenguqulo [ye-Intanethi]. I-Kenilworth (NJ): iMerck kunye ne-Co Inc. .; c2017. Isishwankathelo sePorphyria; [icatshulwe ngo-2017 kaDisemba 20]; [malunga nezikrini ezi-2]. Ifumaneka kwi: http://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/porphyrias/overview-of-porphyria
13. Umdibaniso wencwadi yomsebenzisi yenguqulo [ye-Intanethi]. I-Kenilworth (NJ): iMerck kunye ne-Co Inc. .; c2017. IPorphyria Cutanea Tarda; [icatshulwe ngo-2017 kaDisemba 20]; [malunga nezikrini ezi-3]. Ifumaneka kwi: http://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/porphyrias/porphyria-cutanea-tarda
14. Intliziyo kaZwelonke, iMiphunga, kunye neZiko leGazi [kwi-Intanethi]. I-Bethesda (MD): Isebe lezeMpilo laseMelika kunye neeNkonzo zoLuntu; Uvavanyo lwegazi; [icatshulwe ngo-2017 kaDisemba 20]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.nhlbi.nih.gov/health-topics/blood-tests
15. IZiko leLizwe leSwekile kunye neZifo zeDigestive kunye neZintso [i-Intanethi]. I-Bethesda (MD): Isebe lezeMpilo laseMelika kunye neeNkonzo zoLuntu; IPorphyria; 2014 Feb [icatshulwe ngowama-2017 kweyoMnga-20]; [malunga nezikrini ezi-4]. Ifumaneka kwi: https://www.niddk.nih.gov/health-information/liver-disease/porphyria
16. IYunivesithi yaseRochester Medical Centre [i-Intanethi]. URochester (NY): KwiYunivesithi yaseRochester Medical Centre; c2017. I-Health Encyclopedia: IiPorphyrins (uMchamo); [icatshulwe ngo-2017 kaDisemba 20]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=porphyrins_urine

Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.