IPrednisone vs.Prednisolone yeUlcerative Colitis

Umxholo

• I-Prednisone kunye ne-prednisolone
• Ukuthelekiswa kwecala ngecala
• Iindleko, ukufumaneka, kunye ne-inshurensi yokugubungela
• Imiphumela
• Ukusebenzisana kweziyobisi
• Sebenzisa nezinye iimeko zonyango
• Ingcebiso ka-Pharmacist

Intshayelelo

Xa kuziwa kwi-ulcerative colitis, kukho iindlela ezahlukeneyo zonyango. Zininzi iintlobo ezahlukeneyo zamachiza ezikhoyo. Unyango oluyalelwa ngugqirha uhlala uxhomekeke kubukhali beempawu zakho.

Amachiza amabini onokuweva malunga ne-prednisone kunye ne-prednisolone. (Iyeza lesithathu, i-methylprednisolone, lomelele kunezimbini kwaye akufuneki lidideke ne-prednisolone.) Nantsi ingqokelela yokuba zintoni na ezi ziyobisi kunye nendlela ezinokunceda ngayo ukunyanga i-ulcerative colitis, kubandakanya ukuba ziyafana njani kwaye zahluke njani.

I-Prednisone kunye ne-prednisolone

I-Prednisone kunye ne-prednisolone bobabini bakudidi lweziyobisi ekuthiwa zii-glucocorticoids. IiGlucocorticoids zinciphisa ukudumba emzimbeni wakho wonke. Benza oku ngokungenelela kwindlela ezithile zeekhemikhali emzimbeni wakho ezibangela ukudumba.

La machiza anokusebenza kwiindawo ezahlukeneyo zomzimba wakho, kubandakanya ikholoni yakho. Ikholoni yakho licandelo lokugqibela lamathumbu akho amakhulu, nje ngaphambi kwethambo lakho. Ngokunciphisa ukudumba apho, la machiza anceda ukunciphisa umonakalo owenziwa yi-colitis kwikholoni yakho.

Akukho nanye kula machiza anyanga i-colitis, kodwa zombini inokukunceda ukuyilawula kunye nokuphucula umgangatho wobomi. La machiza akhulula iimpawu eziqhelekileyo ezinje:

• isisu kunye neentlungu
• ukuhla ukusinda
• urhudo
• ukudinwa

Ukuthelekiswa kwecala ngecala

I-Prednisone kunye ne-prednisolone ngamachiza afanayo. Le theyibhile ilandelayo ithelekisa ukufana nokwahluka kweempawu ezininzi zala machiza mabini.

Iindleko, ukufumaneka, kunye ne-inshurensi yokugubungela

Iindleko zePrednisolone kunye ne-prednisone malunga nokufanayo. Omabini la machiza eza ngohlobo oluqhelekileyo kunye negama lophawu. Njengazo zonke iziyobisi, iinguqulelo eziqhelekileyo zale mihla zihlala zibiza imali encinci. I-GoodRx.com inokukunika uluvo lweendleko ezikhoyo zamachiza amiselwe ngugqirha wakho.

Nangona kunjalo, ayizizo zonke iichemicals ezikhoyo kwiifom okanye kumandla afanayo neenguqulelo zegama lophawu. Buza umboneleli wakho wezononophelo lwempilo ukuba kunyanzelekile ukuba uthathe amandla egama legama okanye ifom.

Uninzi lweekhemesti zigcina iinguqulelo eziqhelekileyo zohlobo lwe-prednisone kunye ne-prednisolone. Iinguqulelo zamagama ezorhwebo azihlali zigciniwe, ngoko ke fowunela phambili ngaphambi kokuba ugcwalise amayeza akho ukuba uthatha uhlobo lwegama lophawu.

Uninzi lwezicwangciso zeinshurensi zikwagubungela zombini i-prednisone kunye ne-prednisolone. Nangona kunjalo, inkampani yakho yeinshurensi inokufuna ugunyaziso lwangaphambili kugqirha wakho ngaphambi kokuba avume amayeza kwaye ahlawule intlawulo.

Imiphumela

La machiza avela kudidi olunye lweziyobisi kwaye asebenza ngendlela efanayo. Ngenxa yoku, iziphumo ebezingalindelekanga ze-prednisone kunye ne-prednisolone nazo ziyafana. Nangona kunjalo, bahlukile ngeendlela ezimbalwa. I-Prednisone inokubangela ukuba imeko yakho itshintshe kwaye inokukwenza uzive uxinezelekile. I-Prednisolone inokubangela ukuxhuzula.

Ukusebenzisana kweziyobisi

La machiza alandelayo ayasebenzisana kunye ne-prednisolone kunye ne-prednisone:

• iziyobisi ezichasene nokuhlutha ezifana ne-phenobarbital kunye ne-phenytoin
• i-rifampin, enyanga isifo sephepha
• ketoconazole, enyanga izifo zokungunda
• Iasprini
• abacoci gazi abanjenge warfarin
• zonke izitofu eziphilayo

Sebenzisa nezinye iimeko zonyango

Ukuba unezinye iimeko ngaphandle kwesilonda esilimaza ulcerative, qiniseka ukuba ugqirha uyazi ngazo. Zombini i-prednisone kunye ne-prednisolone zinokwenza iimeko ezithile ezikhoyo zibe mandundu. Oku kubandakanya:

• hypothyroidism
• ukuqina kwesibindi
• herpes simplex iliso
• iingxaki zengqondo
• isigulo sengqondo
• izilonda
• iingxaki zezintso
• igazi elonyukayo
• osteoporosis
• imysthenia gravis
• isifo sephepha

Ingcebiso ka-Pharmacist

I-Prednisone kunye ne-prednisolone zinokufana ngakumbi kunomahluko. Umahluko omkhulu phakathi kwala machiza zezinye iziyobisi abanxibelelana nazo. Nika ugqirha wakho uluhlu olupheleleyo lwamachiza kunye nezongezelelo ozithathayo. Oku kunokuba lolunye lolona lwazi lubalaseleyo onokuthi ulunike ugqirha wakho ukubanceda benze isigqibo phakathi kwala machiza mabini ukunyanga isifo sakho sokudumba okwenziwa sisilonda sikabhobhosi.