Ngaba ubuso bakho buba bomvu xa usela? Nantsi kutheni

Umxholo

• Ngubani ochaphazeleka lula?
• Kwenzekani?
• Iyingozi?
• Unyango
• Ngaba ndingayikhusela?
• Izilumkiso
• Umgca wezantsi

Utywala kunye nokugungxula ebusweni

Ukuba ubuso bakho bujikajika bubomvu emva kweglasi ezimbalwa zewayini, awuwedwa. Abantu abaninzi banamava okugungxula ubuso xa besela utywala. Igama lobuchwephesha kule meko "kukusela utywala."

Uninzi lwexesha, ukugungxulwa kwenzeka kuba unengxaki yokugaya utywala ngokupheleleyo.

Abantu abagungxulayo xa besela banokuba nenguqulelo engalunganga yealdehyde dehydrogenase 2 (ALDH2) gene. I-ALDH2 yi-enzyme emzimbeni wakho enceda ukwahlula into enotywala ebizwa ngokuba yi-acetaldehyde.

I-acetaldehyde eninzi inokubangela ubuso obomvu kunye nezinye iimpawu.

Funda ukuze ufunde ngakumbi malunga nokuba kutheni ukugungxula kwenzeka kunye nento onokuyenza ngayo.

Ngubani ochaphazeleka lula?

Izazinzulu ziqikelela ukuba ubuncinci abantu kwihlabathi liphela abanesiphene se-ALDH2. Yimalunga neepesenti ezisibhozo zabemi.

Abantu baseJapan, amaTshayina, kunye nabaseKorea banamathuba okuba baphendule gwenxa. Ubuncinci, kwaye mhlawumbi ukuya kuthi ga kwiipesenti ezingama-70, zabantu baseMpuma Asiya banamava okugungxula ubuso njengempendulo yokusela utywala.

Ngapha koko, ubuso obomvu buqhele ukubizwa ngokuba yi "Asian flush" okanye "ukukhanya kweAsia."

Olunye uphando luye lwabonisa ukuba abantu abanemvelaphi yamaJuda banokubakho ngakumbi ekuguqukeni kwe-ALDH2.

Ayaziwa ukuba kutheni abantu abathile kusenokwenzeka ukuba babe nale ngxaki, kodwa yinto yemfuza kwaye ingadluliselwa ngomnye okanye bobabini abazali.

Kwenzekani?

I-ALDH2 ihlala isebenza ukophula i-acetaldehyde. Xa utshintsho lwemfuza luchaphazela le enzyme, ayenzi msebenzi wayo.

Ukusilela kwe-ALDH2 kubangela i-acetaldehyde engakumbi ukuba yakhe emzimbeni wakho. I-acetaldehyde eninzi inokukwenza ungabunyamezeli utywala.

Ukugungxula luphawu olunye, kodwa abantu abakule meko banokuba namava:

• ukubetha kwentliziyo ngokukhawuleza
• intloko ebuhlungu
• isicaphucaphu
• ukugabha

Iyingozi?

Ngelixa ukugungxula ngokwako kungeyongozi, isenokuba ngumqondiso osisilumkiso wobunye ubungozi.

Olunye uphononongo luka-2013 lubonise ukuba abantu abagungxulwayo emva kokuba besele banokuba nethuba eliphezulu lokuphucula uxinzelelo lwegazi.

Izazinzulu zijonge amadoda angama-1,763 aseKorea kwaye zafumanisa ukuba "i-flushers" ezazisela ngaphezulu kwezine iziselo ezinxilisayo ngeveki zazinomngcipheko omkhulu wokukhula koxinzelelo lwegazi xa kuthelekiswa nabo bangaselanga tu.

Kodwa, "ii-non-flusher" zazinokwenzeka kuphela ukuba zibe noxinzelelo lwegazi oluphezulu ukuba babeneziselo ezingaphezulu kwesibhozo ngeveki.

Ukuba noxinzelelo lwegazi kunokunyusa amathuba okuba ube nesifo sentliziyo kunye nokufa icala.

Izifundo ezili-10 ezahlukeneyo zafumanisa ukuba ukuphendula ngobuso etywaleni kunxulunyaniswa nomngcipheko ophezulu womhlaza, ngakumbi umhlaza wokuqina, emadodeni aseMpuma Asia. Kwakungadibani nomngcipheko womhlaza phakathi kwabafazi.

Abanye oogqirha bakholelwa ukuba isiphumo sokugungxula kunokuba luncedo ekuchongeni abo basemngciphekweni wezi zifo.

Unyango

Amayeza abizwa ngokuba yi-histamine-2 (H2) blocker angalawula ukugungxula ebusweni. La machiza asebenza ngokucothisa ukonakala kotywala kwi-acetaldehyde kwigazi lakho. Iibhlokhi eziqhelekileyo zeH2 zibandakanya:

• Ipepcid
• Zantac
• I-Tagamet

I-Brimonidine lolunye unyango oludumileyo lokugungxula ubuso. Lulungiso lwezihloko olunciphisa ukubomvu kobuso okwethutyana. Iyeza lisebenza ngokunciphisa ubungakanani bemithambo yegazi encinci.

Ulawulo lwe-US Food and Drug Administration (FDA) lwamkele i-brimonidine kunyango lwe-rosacea-imeko yolusu ebangela ubomvu kunye namaqhuma amancinci ebusweni.

Enye i-cream ye-cream, i-oxymetazoline, yavunywa ngo-2017 ukunyanga i-rosacea. Inokukunceda ukubomvu kobuso ngokunciphisa imithana yegazi kulusu.

Abanye abantu basebenzisa ii-lasers kunye nonyango olusekwe ekukhanyeni ukunciphisa ubomvu. Unyango lunokunceda ukuphucula ukubonakala kwemithambo yegazi ebonakalayo.

Kubalulekile ukwazi ukuba unyango lokunceda ukugungxula alujongane nokusilela kwe-ALDH2. Banokufihla iimpawu ezibalulekileyo ezinokubonisa ingxaki.

Ngaba ndingayikhusela?

Ekuphela kwendlela yokuthintela ukugungxwa bubuso xa usela kukuphepha okanye ukunciphisa ukusela utywala. Oku kunokuba ngumbono olungileyo, nokuba awunangxaki ngokujika ubomvu.

Ngokwe-World Health Organisation (i-WHO), utywala bunoxanduva ngaphezu kwabantu abaswelekileyo kwihlabathi liphela.

I-WHO ithi utywala "bubangela obuninzi" ngaphezu kokulimala.

Utywala obuninzi bunokunyusa umngcipheko wokuphuhlisa uninzi lweengxaki zonyango, kubandakanya:

• isifo sesibindi
• imihlaza ethile
• igazi elonyukayo
• isifo sentliziyo okanye ukubetha
• iingxaki zememori
• Imicimbi yokwetyisa
• ukuxhomekeka etywaleni

Ukuba uyasela, zama ukusela ngobungcathu. Ukuchaza ukusela "ngcathu" njengokuselwa kube kanye ngosuku kwabasetyhini ukuya kuthi ga kwiziselo ezibini ngosuku emadodeni.

Izilumkiso

Amayeza afihle iimpawu zokunganyamezelani notywala anokukwenza uzive ngathi ungasela ngaphezu kokuba kufanele. Oku kunokuba yingozi, ngakumbi ukuba une-ALDH2.

Khumbula, ukugungxula ebusweni kunokuba luphawu lokuba uyeke ukusela.

Umgca wezantsi

Ukuhlanjwa kobuso ngelixa usela kuhlala kubangelwa kukusilela kwe-ALDH2, okunokwenza ukuba ukusela utywala kube yingozi empilweni yakho. Abantu abanemvelaphi yaseAsia kunye namaJuda kunokwenzeka ukuba babe nale ngxaki.

Ngelixa unyango lunokufihla ubomvu, zigubungela kuphela iimpawu zakho. Ukuba ujongene nokugungxwa ebusweni ngelixa usela, kuya kufuneka uzame ukunciphisa okanye ukunqanda utywala.

Thetha nogqirha wakho ukuba ucinga ukuba unokuswela i-ALDH2. Iimvavanyo ziyafumaneka ukuqinisekisa ukuba uguqukile ufuzo.