Somatostatinomas

Umxholo

• Iimpawu ze-somatostatinoma
• Oonobangela kunye nemingcipheko yezinto ze-somatostatinomas
• Zifunyaniswa njani ezi tumors?
• Baphathwa njani?
• Iimeko ezihambelanayo kunye neengxaki
• Inqanaba lokusinda kwi-somatostatinomas

Ushwankathelo

I-somatostatinoma luhlobo olunqabileyo lwe-neuroendocrine tumor ekhula kwi-pancreas kwaye ngamanye amaxesha isilwanyana esincinci. Ithumba le-neuroendocrine lelinye elenziwa ziiseli ezivelisa iihomoni. Ezi seli zivelisa iihomoni kuthiwa zii-islet cells.

I-somatostatinoma ikhula ngokukodwa kwi-delta islet cell, enoxanduva lokuvelisa i-hormone somatostatin. Ithumba lenza ukuba ezi seli zivelise ngakumbi le hormone.

Xa umzimba wakho uvelisa iihomoni ze-somatostatin, iyeka ukuvelisa ezinye iihomoni zepancreatic. Xa ezinye iihomoni ziba zinqabile, ekugqibeleni zikhokelela kwiimpawu ezibonakalayo.

Iimpawu ze-somatostatinoma

Iimpawu ze-somatostatinoma zihlala ziqala kancinci kwaye zonyusa ubungqongqo ngokuthe ngcembe. Ezi mpawu ziyafana nezo zibangelwa zezinye iimeko zonyango. Ngesi sizathu, kubalulekile ukuba wenze idinga nogqirha wakho ukufumana uxilongo oluchanekileyo. Oku kuya kuqinisekisa unyango olululo kuyo nayiphi na imeko yonyango exhomekeke kwiimpawu zakho.

Iimpawu ezibangelwa yi-somatostatinoma zingabandakanya oku kulandelayo:

• iintlungu esiswini (olona phawu luqhelekileyo)
• isifo seswekile
• ukwehla kobunzima obungachazwanga
• ngamatye enyongo
• i-steatorrhea, okanye izitulo ezinamafutha
• ukuvaleka kwamathumbu
• urhudo
• i-jaundice, okanye isikhumba esityheli (esiqhelekileyo xa i-somatostatinoma isesibilinini esincinci)

Iimeko zonyango ngaphandle kwe-somatostatinoma zinokubangela uninzi lweempawu. Oku kuhlala kunjalo, njengoko ii-somatostatinomas zinqabile. Nangona kunjalo, ngugqirha wakho kuphela onokuchonga imeko echanekileyo emva kweempawu zakho ezithile.

Oonobangela kunye nemingcipheko yezinto ze-somatostatinomas

Yintoni ebangela i-somatostatinoma okwangoku ayaziwa. Nangona kunjalo, kukho izinto ezinobungozi ezinokubangela i-somatostatinoma.

Le meko inokuchaphazela abesilisa nabasetyhini, ihlala yenzekile emva kweminyaka engama-50. Ezi zilandelayo zezinye zezinto ezinokuba semngciphekweni wamathumba e-neuroendocrine:

• Imbali yosapho ye-endocrine neoplasia yohlobo 1 (MEN1), uhlobo olunqabileyo lomhlaza wesifo esifa
• neurofibromatosis
• Isifo se-von Hippel-Lindau
• Isifo sokuqina kwemithambo

Zifunyaniswa njani ezi tumors?

Uxilongo kufuneka lwenziwe yingcali yezonyango. Ugqirha wakho uhlala eqala inkqubo yovavanyo ngovavanyo lokuzila ukutya kwegazi. Olu vavanyo lujonga inqanaba le-somatostatin ephezulu. Uvavanyo lwegazi luhlala lulandelwa yenye okanye ezingaphezulu kwezi ziskeni zokuxilonga okanye ii-X-ray:

• i-endoscopic ultrasound
• Ukuskena i-CT
• i-octreoscan (eskena ukuskena ngemitha)
• Ukuskena iMRI

Olu vavanyo luvumela ugqirha wakho ukuba alibone ithumba, elinokuba ngumhlaza okanye lingabinamhlaza. Uninzi lwe-somatostatinomas ngumhlaza. Ekuphela kwendlela yokufumanisa ukuba ngaba umhlaza wakho unesifo somhlaza kukuhlinzwa na.

Baphathwa njani?

I-somatostatinoma ihlala inyangwa ngokususa ithumba ngotyando. Ukuba i-tumor inomhlaza kwaye umhlaza usasazekile (imeko ebizwa ngokuba yi-metastasis), utyando alunakukhetha. Kwimeko ye-metastasis, ugqirha wakho uya kunyanga kwaye aphathe naziphi na iimpawu ezinokubangelwa yi-somatostatinoma.

Iimeko ezihambelanayo kunye neengxaki

Ezinye zeemeko ezinxulunyaniswa ne-somatostatinomas zinokubandakanya oku kulandelayo:

• Isifo sikaV von Hippel-Lindau
• AMADODA1
• Uhlobo lwe-neurofibromatosis 1
• iswekile yemellitus

I-Somatostatinomas zihlala zifunyanwa kamva, ezinokuthi zibe nzima kunyango. Kwixesha elidlulileyo, izicubu zomhlaza kunokwenzeka ukuba sele sele zisetyenzisiwe. Emva kwe-metastasis, unyango lilinganiselwe, kuba utyando ngokuqhelekileyo alunakukhetha.

Inqanaba lokusinda kwi-somatostatinomas

Ngaphandle kwendalo enqabileyo ye-somatostatinomas, imbonakalo ilungile kwinqanaba lokusinda leminyaka emi-5. Xa i-somatostatinoma ingasuswa ngotyando, kukho malunga neepesenti ezili-100 zokuphila iminyaka emihlanu emva kokususwa. Inqanaba lokusinda kweminyaka emihlanu kwabo baphathwa emva kwe-somatostatinoma sele i-metastasized yi-60 yepesenti.

Isitshixo kukufumana uxilongo kwangoko. Ukuba unempawu ezithile ze-somatostatinoma, kuya kufuneka wenze idinga nogqirha wakho ngokukhawuleza. Uvavanyo lokuchonga luya kuba nakho ukufumanisa esona sizathu seempawu zakho.

Ukuba ugqirha wakho ufumanisa ukuba une-somatostatinoma, kwangoko uqala unyango, kokukhona imeko yakho iya kuba ngcono.