Ukuvavanywa ngokuthe ngqo nangokungathanga ngqo kwe-coomb: iyintoni kwaye yenzelwe ntoni

Umxholo

• Luqhutywa njani uviwo
• Oko kuthethwa sisiphumo

Uvavanyo lwe-coomb luhlobo lovavanyo lwegazi oluvavanya ubukho beentsholongwane ezithile ezihlasela iiseli ezibomvu zegazi, zibangela ukutshatyalaliswa kwazo kwaye zikhokelele ekubonakaleni kohlobo lwe-anemia eyaziwa ngokuba yi-hemolytic.

Zimbini iintlobo eziphambili zolu viwo, ezibandakanya:

• Uvavanyo lweeCombs ngqo: kuvavanya ngokuthe ngqo iiseli ezibomvu zegazi, ukujonga ii-antibodies eziqhotyoshelwe kwiseli ebomvu yegazi nokuba ngaba ezi zithintelo zithatyathwe kwinkqubo yomzimba yokuzikhusela okanye zifunyenwe ngokutofelwa. Olu vavanyo luhlala lwenziwa ukuze kufunyanwe i-autoimmune hemolytic anemias- Jonga ukuba zeziphi iimpawu ezinokubonisa i-hemolytic anemia;
• Uvavanyo lweeCombs ezingangqalanga: kuvavanywa i-serum yegazi, ichonga izilwa-buhlungu ezikhoyo apho, kwaye kuhlala kucelwa kwiimeko zotofelo-gazi, ukuqinisekisa ukuba igazi ekufuneka linikelwe liyahambelana nomamkeli.

Ukongeza kwi-anemia, olu vavanyo lunokunceda ekuchongeni ezinye izifo ezichaphazela iiseli zegazi ezinje ngeleukemia, lupus, mononucleosis kunye ne-fetus erythroblastosis, ekwabizwa ngokuba sisifo sehemolytic sosana olusandul 'ukuzalwa, kunye nokuchonga umngcipheko wokuphendulwa kwegazi. Funda ngakumbi malunga ne-erythroblastosis yomntwana.

Luqhutywa njani uviwo

Uvavanyo lweCoombs lwenziwa kwisampulu yegazi, ekufuneka iqokelelwe kwilabhoratri yovavanyo lweklinikhi. Igazi eliqokelelweyo lithunyelwa elebhu, apho uvavanyo lweCoombs ngqo okanye olungathanga ngqo luya kwenziwa khona, kuxhomekeke kwinjongo.

Kuvavanyo oluthe ngqo lweCoombs, i-rehlisi yeCoombs yongezwa kwigazi lesigulana, ivumela ukubonwa kweentsholongwane ezinokudibaniswa neeseli ezibomvu zegazi. Kuvavanyo lweCoombs olungathanga ngqo, igazi liyaqokelelwa lize lifakwe kwisirinji, lahlula iiseli ezibomvu zegazi kwi-serum, equlathe izilwa-buhlungu. Kwiserum, iiseli ezibomvu 'ezibhalwe kwangaphambili' ezinee-antibodies ziyongezwa ukukhangela ukuba ngaba kukho ii-autoantibodies ezikhoyo kwiseramu kwaye, ngenxa yoko, kwigazi lesigulana.

Ukwenza uvavanyo lweCombombs, akukho lungiselelo luyimfuneko, kodwa amanye amayeza anokuphazamisa isiphumo, ke kubalulekile ukuba wazise ugqirha malunga nokusetyenziswa kwawo ukuze kunikwe isikhokelo ngokumiswa kwakhe.

Oko kuthethwa sisiphumo

Iziphumo zovavanyo lwe-Coombs aluniki xa kungekho antibody ebangela ukutshatyalaliswa kweembumba ezibomvu, yiyo loo nto ithathwa njengeziphumo eziqhelekileyo.

Nangona kunjalo, xa iziphumo zichanekile, oko kuthetha ukuba kukho i-antibody egazini kwaye, ke ngoko, ukuba iziphumo zilungile kuvavanyo lwe-Coombs ngqo oko kuthetha ukuba umntu unokuba nesifo esifana:

• I-anemia ye-hemolytic autoimmune;
• Usulelo ngo Mycoplasma sp.;
• Negcushuwa;
• Wegazi;
• Ilupus erythematosus;
• Mononucleosis.

Kwimeko yovavanyo olungqalileyo lweeCombs, iziphumo ezincumisayo zithetha ukuba umntu une-antibody enokubangela amahlwili xa efumana olunye uhlobo lwegazi, ke ngoko, kufuneka ulumke xa usenza utofelo-gazi.

Ngayiphi na imeko, kuhlala kubalulekile ukuba isiphumo sivavanywe ngugqirha osicelileyo, kuba imvelaphi yomntu othile inokutshintsha iziphumo.