Ukubeka iliso kunyango lweziyobisi
Umxholo
- Yintoni unyango lokujonga iziyobisi (TDM)?
- Isetyenziselwa ntoni?
- Kutheni ndifuna i-TDM?
- Kwenzeka ntoni ngexesha le-TDM?
- Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
- Ngaba kukho nayiphi na ingozi kwi-TDM?
- Zithetha ntoni iziphumo?
- Izalathiso
Yintoni unyango lokujonga iziyobisi (TDM)?
Ukubeka iliso kunyango lweziyobisi (i-TDM) kuvavanyo olulinganisa isixa samayeza athile egazini lakho. Kuyenziwa ukuqinisekisa ukuba inani lamayeza owasebenzisayo likhuselekile kwaye liyasebenza.
Uninzi lwamayeza anokutsalwa ngokuchanekileyo ngaphandle kovavanyo olulodwa. Kodwa kwiintlobo ezithile zamayeza, kunokuba nzima ukufumana idosi ebonelela ngamayeza aneleyo ukunyanga imeko yakho ngaphandle kokubangela iziphumo ebezingalindelekanga eziyingozi. I-TDM inceda umboneleli wakho afumanise ukuba ngaba uthatha idosi efanelekileyo yeyeza lakho.
Amanye amagama: amanqanaba amayeza kuvavanyo lwegazi, amanqanaba onyango onyango
Isetyenziselwa ntoni?
Ukubeka iliso kunyango lweziyobisi (i-TDM) kusetyenziselwa ukumisela ezona dosi zilungileyo zabantu abathatha iintlobo ezithile zamayeza anzima ukuya kwidosi. Apha ngezantsi kukho amanye amayeza aqhelekileyo ekufuneka abekwe esweni.
Iindidi zonyango | Amagama amayeza |
---|---|
Amayeza okubulala iintsholongwane | vancomycin, gentamycin, amakacin |
Iziyobisi zentliziyo | I-digoxin, i-procainamide, i-lidocaine |
Iziyobisi ezichasene nokuhlutha | phenytoin, lumka |
Iziyobisi ziphatha izifo ezizimele | cyclosporine, itacrolimus |
Iziyobisi ezinyanga ukuphazamiseka kwengqondo | lithium, valproic acid |
Kutheni ndifuna i-TDM?
Unokufuna uvavanyo xa uqala ukuthatha iyeza. Oku kunceda umboneleli wakho abone eyona dosi isebenzayo kuwe. Nje ukuba idosi imiselwe, unokuvavanywa rhoqo ukuqinisekisa ukuba iyeza lisasebenza ngaphandle kokulimaza. Unokufuna uvavanyo ukuba unempawu zesiphumo esibi. Iziphumo ziyahluka ngokuxhomekeke kunyango. Umboneleli wakho wezempilo uya kukwazisa ukuba zeziphi iimpawu ekufuneka uzilindile.
Kwenzeka ntoni ngexesha le-TDM?
Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.
Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
Kuxhomekeke kuhlobo lwamayeza owathathayo, unokufuna ukucwangcisa uvavanyo lwakho ngaphambi okanye emva kokuba uthathe idosi yakho yesiqhelo.
Ngaba kukho nayiphi na ingozi kwi-TDM?
Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.
Zithetha ntoni iziphumo?
Iziphumo zakho ziya kubonisa ukuba amanqanaba amayeza egazini lakho kuluhlu oluncedo kwezonyango kodwa aluyongozi. Oku kubizwa ngokuba luhlu lonyango. Uluhlu luyahluka ngokuxhomekeka kuhlobo lwamayeza kunye neemfuno zakho zempilo. Ukuba iziphumo zakho azikho kolu luhlu, umboneleli wakho unokufuna uhlengahlengiso kwiidosi zakho. Ukuba iidosi zakho zitshintshiwe, unokufumana iimvavanyo eziphindaphindiweyo de amanqanaba akho amayeza awele kuluhlu lonyango.
Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho wezempilo.
Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.
Izalathiso
- I-DoveMed [Intanethi]. Ihobe; c2019. Ukubeka iliso kwiziyobisi; I-2014 Mar 8 [ihlaziyiwe ngo-2018 ngoMatshi 25; icatshulwe ngo-2020 kuMatshi 27]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.dovemed.com/common-procedures/procedures-laboratory/therapeutic-drug-monitoring-tdm
- Kang JS, uLee MH. Amagqabantshintshi ovavanyo lweziyobisi zonyango. I-Korea J yangaphakathi. [Intanethi]. 2009 Mar [icatshulwe ngowama-2020 kuMatshi 27]; 24 (1): 1–10. Ifumaneka kwi: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687654
- Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC: Umbutho waseMelika weKlinikhi yeKhemistry; c2001-2020. Ukubeka iliso kwiziyobisi; [ihlaziywe ngo-2018 Dec 16; icatshulwe ngo-2020 kuMatshi 27]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://labtestsonline.org/tests/therapeutic-drug-monitoring
- Intliziyo kaZwelonke, iMiphunga, kunye neZiko leGazi [kwi-Intanethi]. I-Bethesda (MD): Isebe lezeMpilo laseMelika kunye neeNkonzo zoLuntu; Uvavanyo lwegazi; [icatshulwe ngowama-2020 kuMatshi 27]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.nhlbi.nih.gov/health-topics/blood-tests
- Impilo ye-UF: iYunivesithi yaseFlorida yezeMpilo [i-Intanethi]. IGainesville (FL): yeYunivesithi yaseFlorida yezeMpilo; c2020. Amanqanaba onyango onyango: Ubume; [ihlaziyiwe ngo-2020 nge-27 kaMatshi; icatshulwe ngo-2020 kuMatshi 27]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://ufhealth.org/therapeutic-drug-levels
- Ezempilo ze-UW [kwi-Intanethi]. Madison (WI): Izibhedlele zeYunivesithi yaseWisconsin kunye neGunya leKlinikhi; c2020. Ulwazi lwezeMpilo: Amanqanaba oNyango kwiGazi: Iziphumo; [ihlaziywe ngo-2019 Dec 8; icatshulwe ngo-2020 kuMatshi 27]; [malunga nezikrini ezi-8]. Ifumaneka kwi: https://www.uwhealth.org/health/topic/medicaltest/medicine-levels-in-blood/abq4055.html#abq4062
- Ezempilo ze-UW [kwi-Intanethi]. Madison (WI): Izibhedlele zeYunivesithi yaseWisconsin kunye neGunya leKlinikhi; c2020. Ulwazi lwezeMpilo: Amanqanaba oNyango eGazini: Uvavanyo ngokubanzi; [ihlaziywe ngo-2019 Dec 8; icatshulwe ngo-2020 kuMatshi 27]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.uwhealth.org/health/topic/medicaltest/medicine-levels-in-blood/abq4055.html#abq4056
- Ezempilo ze-UW [kwi-Intanethi]. Madison (WI): Izibhedlele zeYunivesithi yaseWisconsin kunye neGunya leKlinikhi; c2020. Ulwazi lwezeMpilo: Amanqanaba oNyango eGazini: Kutheni le nto yenziwa; [ihlaziywe ngo-2019 Dec 8; icatshulwe ngo-2020 kuMatshi 27]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.uwhealth.org/health/topic/medicaltest/medicine-levels-in-blood/abq4055.html#abq4057
Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.