I-Topiramate: yintoni kunye nemiphumo emibi

Umxholo

• Kusetyenziswa kwanjani
• 1. Unyango oluncedayo lwesifo sokuwa
• 2. Unyango lwe-monotherapy
• 3. Imigraine prophylaxis
• Ngubani ongafanele asebenzise
• Iziphumo ebezingalindelekanga ezinokwenzeka

I-Topiramate yintsholongwane ye-anticonvulsant eyaziwa ngokuba yi-Topamax, esebenza kwinkqubo ye-nervous system, izinzisa imizwa, kwaye ikhusele ingqondo. Eli yeza libonakalisiwe kunyango lwesifo sokuwa kubantu abadala nasebantwaneni, kunyango lweengxaki ezinxulunyaniswa neLennox-Gastaut Syndrome kunye nonyango lwe-migraine.

I-Topiramate inokuthengwa ezikhemesti, ngexabiso elimalunga nama-60 ukuya kuma-300 reais, kuxhomekeke kwidosi, ubungakanani bokupakishwa kunye negama leziyobisi, kwaye kukwakho nokukhetha i-generic.

Kusetyenziswa kwanjani

Unyango kufuneka luqale ngedosi esezantsi, ekufuneka inyuswe ngokuthe chu, de kube kufikelelwe idosi efanelekileyo.

1. Unyango oluncedayo lwesifo sokuwa

Elona thamo lisezantsi elisebenzayo li-200 mg ngosuku, ukuya kuthi ga kwi-1600 mg ngosuku, ethathwa njengeyona dosi iphezulu. Unyango kufuneka luqale nge-25 ukuya kwi-50 mg, elawulwa ngokuhlwa, iveki enye. Emva koko, ngekhefu le-1 okanye i-2 iiveki, idosi kufuneka inyuswe nge-25 ukuya kwi-50 mg / ngosuku kwaye yahlulwe yangamanani amabini.

Kubantwana abangaphezulu kweminyaka emi-2 ubudala, idosi yemihla ngemihla ekhuthazwayo yi-5 ukuya kwi-9 mg / kg ngosuku, yahlulwe yangamacandelo amabini olawulo.

2. Unyango lwe-monotherapy

Xa ezinye iziyobisi ze-antiepileptic zisuswe kwisicwangciso sonyango, ukuze kugcinwe unyango kunye ne-topiramate njenge-monotherapy, iziphumo ezinokubakho kulawulo lokubanjwa kufuneka ziqwalaselwe, ukucebisa, ukuba kunokwenzeka, ukupheliswa ngokuthe ngcembe kunyango lwangaphambili.

Kubantwana abangaphezu kweminyaka emi-2 ubudala, idosi yokuqala iyahluka ukusuka kwi-0.5 ukuya kwi-1 mg / kg ngosuku, ngokuhlwa, kangangeveki. Emva koko, idosi kufuneka inyuswe nge-0.5 ukuya kwi-1 mg / kg ngosuku, ngamakhefu e-1 ukuya kwiiveki ezi-2, yahlulwe yangamalungiselelo amabini.

3. Imigraine prophylaxis

Unyango kufuneka luqale nge-25 mg ngokuhlwa kwiveki enye. Le dosi kufuneka inyuswe nge-25 mg / ngosuku, kanye ngeveki, ukuya kuthi ga kwi-100 mg / ngosuku, yahlulwe yolawulo kabini.

Ngubani ongafanele asebenzise

I-Topiramate ayifanele isetyenziswe ngabantu abaxhalabisayo kwizinto zefomula, kubafazi abakhulelweyo okanye abasetyhini abakrokrela ukuba bakhulelwe.

Iziphumo ebezingalindelekanga ezinokwenzeka

Ezinye zeempembelelo eziqhelekileyo ezinokuthi zenzeke ngexesha lonyango kunye ne-topiramate zokozela, ukuxakeka, ukukhathala, ukukhathazeka, ukulahleka kwesisindo, ukucinga ngokukhawuleza, ukubetha, ukubona kabini, ukulungelelanisa okungaqhelekanga, isicupunu, i-nystagmus, ukunyaniseka, i-anorexia, ubunzima bokuthetha , ukuncipha kokutya, ukukhumbula okungahambi kakuhle kunye norhudo.