I-Transferrin: yintoni, amaxabiso aqhelekileyo kunye nokuba yenzelwe ntoni

Umxholo

• Yenzelwe ntoni
• Yintoni iTransferrin Saturation Index
• Oko kuthetha ukudluliselwa okuphezulu
• Oko kuthetha ukudluliselwa okuphantsi

I-Transferrin yiprotein eveliswa sisibindi kwaye owona msebenzi wayo kukuhambisa intsimbi kumongo, udakada, isibindi kunye nezihlunu, ukugcina ukusebenza komzimba kufanelekile.

Amaxabiso aqhelekileyo okudluliselwa kwegazi kwezi zinto zilandelayo:

• Amadoda: 215 - 365 mg / dL
• Abafazi: 250 - 380 mg / dL

Ukuvavanywa koxinzelelo lwe-transferrin egazini kufuneka kwenziwe nge-8 ukuya kwi-12 ngeyure ngokukhawuleza, kuxhomekeke kwisikhokelo sikagqirha kunye nelabhoratri, kwaye ihlala icelwa kunye ne-iron kunye ne-ferritin dosage, ukongeza kuvavanyo lwe-biochemical kunye ne-hematological. ubalo lwegazi, umzekelo, kufuneka lutolikwe kunye. Yazi ukuba liphi inani legazi nokuba ungalitolika njani.

Yenzelwe ntoni

Idosi ye-transferrin ihlala icelwa ngugqirha ukuba enze uxilongo olwahlukileyo lwe-microcytic anemias, ezo zibonakaliswa bubukho beeseli ezibomvu zegazi ezincinci kunesiqhelo. Ke, ukongeza kwi-transferrin, ugqirha ucela umlinganiso we-serum iron kunye ne-ferritin. Funda ngakumbi malunga neferritin.

Iprofayile yelabhoratri ye-microcytic anemias yile:

Ukongeza kwezi mvavanyo, i-hemoglobin electrophoresis inokucelwa ukuba ichonge uhlobo lwe-hemoglobin yesigulana kwaye, ngenxa yoko, iqinisekise ukuxilongwa kwe-thalassemia, umzekelo.

Kubalulekile ukuba iziphumo zovavanyo zitolikwe ngugqirha, kuba ukongeza kuxinaniso lwentsimbi, i-transferrin kunye ne-ferritin, kubalulekile ukuhlalutya ezinye iimvavanyo ukuze kukhangelwe imeko yeklinikhi ngokubanzi.

Yintoni iTransferrin Saturation Index

I-Transferrin Saturation Index ihambelana nepesenti yokudluliselwa kwentsimbi. Ngaphantsi kweemeko eziqhelekileyo, i-20 ukuya kwi-50% yeendawo zokudlulisa i-transferrin zihlala ngentsimbi.

Kwimeko yokunqongophala kwe-anemia, umzekelo, isalathiso sokugcwalisa i-transferrin sisezantsi ngenxa yokuxinana kwesinyithi okufumaneka egazini. Oko kukuthi, umzimba uqala ukuvelisa i-transferrin engaphezulu ukuzama ukubamba i-iron eninzi ngangokunokwenzeka ukuyisa kwizicubu, kodwa i-transferrin nganye ihambisa i-iron encinci kunokuba kufanelekile.

Oko kuthetha ukudluliselwa okuphezulu

I-transferrin ephezulu ihlala ibonwa kwi-anemia yokusilela kwe-iron, eyaziwa ngokuba yi-iron anemia, ekukhulelweni nasekunyangeni ngokutshintshwa kwehomoni, ngakumbi i-estrogen.

Oko kuthetha ukudluliselwa okuphantsi

Ukudluliselwa okuphantsi kunokwenzeka kwezinye iimeko, ezinje:

• Thalassemia;
• I-Sideroblastic anemia;
• Ukudumba;
• Iimeko apho kukho ilahleko yeeproteni, ezinje ngezifo ezingapheliyo kunye nokutsha, umzekelo;
• Izifo zesibindi nezintso;
• Neoplasms;
• Nephrosis;
• Ukungondleki.

Ukongeza, uxinzelelo lwe-transferrin egazini lunokuncitshiswa nakwi-anemia yesifo esinganyangekiyo, olu luhlobo lwe-anemia oluqhele ukwenzeka kubantu abasesibhedlele kwaye banezifo ezosulelayo ezinganyangekiyo, ukudumba okanye amathumba.