Into ekufuneka uyazi ngaphambi kokuba uthathe iTrazodone yokulala

Umxholo

• Yintoni i-trazodone?
• Ngaba ivunyiwe ukuba isetyenziswe njengesixhobo sokulala?
• Yeyiphi idosi yesiqhelo ye-trazodone njengoncedo lokulala?
• Zithini izibonelelo zetrazodone yokulala?
• Zeziphi izinto ezingalunganga ngokuthatha i-trazodone?
• Ngaba bukhona ubungozi bokuthatha i-trazodone yokulala?
• Umgca wezantsi

Ukuphuthelwa kungaphezu kokungakwazi ukulala ngokwaneleyo ebusuku. Ukuba nengxaki yokulala okanye ukulala kunokuchaphazela zonke iinkalo zobomi bakho, ukusuka emsebenzini kunye nokudlala ukuya kwimpilo yakho. Ukuba unengxaki yokulala, ugqirha wakho usenokuba uxoxe ngokumisela i-trazodone ukunceda.

Ukuba ucinga ukuthatha i-trazodone (Desyrel, Molipaxin, Oleptro, Trazorel, kunye neTrittico), nantsi ingcaciso ebalulekileyo ekufuneka uyiqwalasele.

Yintoni i-trazodone?

I-Trazodone lunyango olugunyazisiweyo ukuze lusebenzise uLawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) njenge-anti-depressant.

Eli yeza lisebenza ngeendlela ezininzi emzimbeni wakho. Enye yezenzo zayo kukulawula i-serotonin ye-neurotransmitter, enceda iiseli zengqondo ukunxibelelana kunye nokuphembelela izinto ezininzi ezinje ngokulala, iingcinga, imood, ukuthanda ukutya kunye nokuziphatha.

Nokuba ngeedosi ezisezantsi, i-trazodone inokubangela ukuba uzive ukhululekile, udiniwe kwaye wozele. Yenza oku ngokuthintela iikhemikhali kwingqondo ezinxibelelana ne-serotonin kunye nezinye i-neurotransmitters, ezinje, 5-HT2A, alpha1 adrenergic receptors, kunye ne-H1 histamine receptors.

Esi siphumo sinokuba sesinye sezizathu eziphambili zokuba i-trazodone isebenza njengesixhobo sokulala.

Njengoninzi lwe-anti-depressant, i-trazodone ikhutshiwe "Isilumkiso seBhokisi emnyama" yi-FDA.

Ukuthatha i-trazodone kuye kwandisa umngcipheko weengcinga zokuzibulala kunye nokuziphatha kwizigulana zabantwana nakwizigulana ezisencinci. Abantu abathatha la mayeza kufuneka bajongwe ngononophelo ngeempawu eziba mandundu kunye nokuvela kweengcinga zokuzibulala kunye nokuziphatha. I-Trazodone ayivunyelwanga ukuba isetyenziswe kwizigulana zabantwana.

Ngaba ivunyiwe ukuba isetyenziswe njengesixhobo sokulala?

Nangona i-FDA ivume i-trazodone ukuba isetyenziswe njengonyango lokudakumba kubantu abadala, iminyaka emininzi oogqirha bayimisele njengoncedo lokulala.

I-FDA iyawavuma amayeza okunyanga iimeko ezithile ngokubhekisele kwiimvavanyo zeklinikhi. Xa oogqirha bemisela iyeza lezinye iimeko ngaphandle kwento eyamkelweyo yi-FDA, yaziwa njengelebheli yokumisela.

Ukusetyenziswa kweelebhile ezingekho kwilebheli yinto exhaphakileyo. Amashumi amabini eepesenti amayeza amiselwe ngaphandle kwelebheli. Oogqirha banokumisela amayeza ngaphandle kwelebheli ngokusekwe kumava abo nakwisigwebo.

Yeyiphi idosi yesiqhelo ye-trazodone njengoncedo lokulala?

I-Trazodone ihlala ichazwa kwiidosi phakathi kwe-25mg ukuya kwi-100mg njengoncedo lokulala.

Nangona kunjalo, bonisa iidosi ezisezantsi ze-trazodone ziyasebenza kwaye kunokubangela ukulala kancinci emini kunye neziphumo ebezingalindelekanga ezimbalwa kuba ichiza lisebenza ngokufutshane.

Zithini izibonelelo zetrazodone yokulala?

Iingcali zincoma unyango lokuziphatha kwengqondo kunye nolunye uhlengahlengiso lokuziphatha njengonyango lokuqala lokungalali kunye neengxaki zokulala.

Ukuba ezi ndlela zonyango azisebenzi kuwe, ugqirha wakho unokumisela i-trazodone yokulala. Ugqirha wakho unokukuyalela ukuba amanye amayeza okulala, anje ngeXanax, Valium, Ativan, kunye namanye (amayeza e-benzodiazepine asebenza ngokufutshane), khange akusebenzele.

Izibonelelo ezimbalwa zetrazodone zibandakanya:

• Unyango olusebenzayo lokulala. Ukusetyenziswa kwe-trazodone yokusilela ukulala kufumanise ukuba iyeza lalisebenza ukuqaqanjelwa sisiseko kunye nasesekondari kwiidosi eziphantsi.
• Iindleko ezincitshisiweyo. I-Trazodone ayibizi kakhulu kunamanye amayeza okulala ngenxa yokuba ifumaneka ngokubanzi.
• Hayi umlutha. Xa kuthelekiswa namanye amayeza, njengeklasi ye-benzodiazepine yamayeza anje ngeValium kunye neXanax, i-trazodone ayisiyiyo umlutha.
• Ngamana unokunceda ukuthintela ukuhla kwengqondo okunxulumene nobudala. I-Trazodone inokunceda ukuphucula ukulala kancinci. Oku kunokucotha iintlobo ezithile zokuhla kwengqondo ezinxulumene nobudala njengememori kubantu abadala.
• Unokuba lukhetho olungcono ukuba ulala ne-apnea. Amanye amayeza okulala anokuchaphazela kakubi ukuphazamiseka kokulala kunye nokulala. Isifundo esincinci sika-2014 sifumanise ukuba i-100mg ye-trazodone inefuthe elihle ekuvuseleleni ubuthongo.

Zeziphi izinto ezingalunganga ngokuthatha i-trazodone?

I-Trazodone inokubangela iziphumo ebezingalindelekanga, ngakumbi xa uqala amayeza.

Olu alukho uluhlu olupheleleyo lweziphumo ebezingalindelekanga. Xoxa ngezinto ezikuxhalabisayo nogqirha wakho okanye usokhemesti ukuba uziva uneziphumo ebezingalindelekanga okanye unezinye iingxaki malunga neyeza lakho

Ezinye iziphumo eziqhelekileyo zetrazodone zibandakanya:

• ukozela
• isiyezi
• ukudinwa
• uvalo
• umlomo owomileyo
• utshintsho lobunzima (malunga neepesenti ezi-5 zabantu abazithathayo)

Ngaba bukhona ubungozi bokuthatha i-trazodone yokulala?

Nangona kunqabile, i-trazodone inokubangela iimpendulo ezinzulu. Tsalela umnxeba kwi-911 okanye kwiinkonzo zongxamiseko zengingqi ukuba ufumana naziphi na iimpawu ezisongela ubomi ezifana nokuphefumla nzima.

Ngokutsho kwe-FDA, ingozi enkulu ibandakanya:

• Iingcinga zokuzibulala. Lo mngcipheko uphezulu kubantu abadala abancinci nakubantwana.
• Isifo seSerotonin. Oku kwenzeka xa i-serotonin eninzi iyakha emzimbeni kwaye inokukhokelela ekuphenduleni okunzulu. Umngcipheko we-serotonin syndrome uphezulu xa uthatha amanye amayeza okanye izongezo eziphakamisa amanqanaba e-serotonin njengamanye amayeza e-migraine. Iimpawu zibandakanya:
  • nemibono, ukuphazamiseka, isiyezi, ukuxhuzula
  • ukwanda kwentliziyo, ubushushu bomzimba, iintloko
  • ukungcangcazela kwemisipha, ukuqina, ingxaki ngokulingana
  • isicaphucaphu, ukugabha, urhudo
• Iimpawu zentliziyo. Umngcipheko wotshintsho kwisingqi sentliziyo uphezulu ukuba sele uneengxaki zentliziyo.

• Umgca wezantsi

  I-Trazodone lunyango oludala oluvunyiweyo ukuba lusetyenziswe yi-FDA ngo-1981 njenge-anti-depressant. Nangona ukusetyenziswa kwe-trazodone yokulala kuyinto eqhelekileyo, ngokwezikhokelo zamva nje ezipapashwe yiAmerican Academy of Sleep Medicine, i-trazodone akufuneki ibe lunyango lokuqala lonyango lokulala.

  Ukunikezelwa kwiidosi ezisezantsi, kunokubangela ukulala kancinci emini okanye ukozela. I-Trazodone ayisiyomlutha, kwaye iziphumo ebezingalindelekanga eziqhelekileyo ngumlomo owomileyo, ukozela, ukuba nesiyezi kunye nokuba nentloko elula.

  I-Trazodone inokubonelela ngezibonelelo kwiimeko ezithile ezinje nge-apnea yokulala ngaphezulu kwezinye izixhobo zokulala.