I-Zytiga (abiraterone): yintoni, yeyiphi kwaye uyisebenzisa njani

Umxholo

• Yenzelwe ntoni
• Kusetyenziswa kwanjani
• Iziphumo ebezingalindelekanga ezinokwenzeka
• Ngubani ongafanelekanga ukuthatha

I-Zytiga liyeza elisetyenziswa kunyango lomhlaza wedlala lobudoda ene-abiraterone acetate njengesithako sayo esisebenzayo. I-Abiraterone inqanda into eyimfuneko kwimveliso yehomoni elawula iimpawu zobudoda, kodwa ezihambelana nokwanda komhlaza. Ke, eli yeza lithintela ukuqhubela phambili kwethumba kwi-Prostate, ekonyusa ixesha lokuphila.

Nangona i-abiraterone kaZytiga ibangela ukuba i-adrenal gland ivelise inani elikhulu le-corticosteroids yendalo, kuqhelekile ukuba ugqirha acebise iziyobisi ze-corticosteroid kunye, ukunceda ukunciphisa ukudumba kweprostate kunye nokuphucula iimpawu, ezifana nobunzima bokuchama okanye imvakalelo yesinyi esipheleleyo, kuba umzekelo.

Eli yeza liyafumaneka kumacwecwe angama-250 mg kwaye amaxabiso aphakathi li-10 ukuya kwi-15 lamawaka reais kwiphakeji nganye, kodwa ikwabandakanywa kuluhlu lweziyobisi ze-SUS.

Yenzelwe ntoni

UZytiga ubonakalisiwe kunyango lomhlaza wamadlala kumadoda amadala xa umhlaza usasazeka emzimbeni. Ingasetyenziselwa emadodeni angakhange aziphucule izifo zawo emva kokugxothwa ekucinezeleni imveliso yehomoni zesini okanye emva kwonyango lwe-chemotherapy kunye ne-docetaxel.

Kusetyenziswa kwanjani

Uyisebenzisa kanjani iZytiga equka ukuthatha iipilisi ezingama-4 250 mg kwidosi enye, malunga neeyure ezi-2 emva kwesidlo. Akukho kutya makutyiwe okungenani iyure enye emva kokusetyenziswa. Musa ukugqitha idosi ephezulu yemihla ngemihla ye-1000 mg.

UZytiga uhlala ethathwa ngokudityaniswa ne-5 okanye i-10 mg ye-prednisone okanye i-prednisolone, kabini ngemini, ngokwesikhokelo sikagqirha.

Iziphumo ebezingalindelekanga ezinokwenzeka

Ukusetyenziswa kweli yeza kunokukhokelela ekubonakaleni kweziphumo ebezingalindelekanga, eziqhelekileyo ezinokubandakanya:

• Ukudumba kwemilenze neenyawo;
• Usulelo lomchamo;
• Ukwanda koxinzelelo lwegazi;
• Ukunyuka kwamafutha egazini;
• Ukunyuka kwentliziyo;
• Iintlungu zesifuba;
• Iingxaki zentliziyo;
• Urhudo;
• Amabala abomvu eluswini.

Kusenokwenzeka ukuba kuncitshiswe amanqanaba e-potassium emzimbeni, nto leyo ekhokelela ekubonakaleni kobuthathaka bemisipha, iicramps kunye nokubetha kwentliziyo.

Ngokubanzi, eli yeza lisetyenziswa phantsi kweliso likagqirha okanye ingcali yezempilo, enje ngomongikazi, oya kuthi akuqonde ukubonakala kwayo nayiphi na kwezi ziphumo, aqalise unyango olufanelekileyo, ukuba kukho imfuneko.

Ngubani ongafanelekanga ukuthatha

I-Zytiga iyaphikiswa kubantu abane-hypersensitive to abiraterone okanye naliphi na icandelo lefomula, kunye nezigulana ezinesibindi esibi. Akufanele ilawulwe kubafazi abakhulelweyo okanye xa bencancisa.