Isifo sePseudotumor cerebri

I-Pseudotumor cerebri syndrome yimeko apho uxinzelelo ngaphakathi kukakayi lonyuka. Ingqondo ichaphazeleka ngendlela imeko ebonakala ngathi ayikho, kodwa hayi, ithumba.

Le meko yenzeka rhoqo kwabasetyhini kunamadoda, ngakumbi kwabasetyhini abatyebileyo abancinci abaneminyaka engama-20 ukuya kwengama-40 ubudala. Inqabile kwiintsana kodwa inokwenzeka ebantwaneni. Ngaphambi kokufikisa, kwenzeka ngokulinganayo kubafana nakumantombazana.

Unobangela awaziwa.

Amayeza athile anokunyusa umngcipheko wokuba nale meko. La mayeza aquka:

• Amiodarone
• Iipilisi zolawulo lokuzalwa ezifana ne-levonorgestrel (Norplant)
• ICclosporine
• ICytarabine
• Ukukhula kwehomoni
• Isotretinoin
• I-Levothyroxine (abantwana)
• Ilithium carbonate
• I-minocycline
• Nalidixic acid
• INitrofurantoin
• IPhenytoin
• I-Steroids (ukuqala okanye ukubamisa)
• I-Sulfa antibiotics
• Tamoxifen
• Itetracycline
• Amachiza athile aneVitamin A, efana ne-cis-retinoic acid (Accutane)

Ezi zinto zilandelayo zikwanxulumene nale meko:

• Isifo esiphantsi
• Isifo se-behcet
• Ukusilela kwezintso okungapheliyo
• Iziphazamiso ze-Endocrine (hormone) ezinje ngesifo iAddison, isifo seCushing, hypoparathyroidism, polycystic ovary syndrome
• Ukulandela unyango (ukudityaniswa) kwe-arteriovenous malformation
• Izifo ezosulelayo ezinje nge-HIV / AIDS, isifo seLyme, kulandela irhashalala ebantwaneni
• Ukunqongophala kwe-anemia
• Ukutyeba kakhulu
• Ukuphefumla kokulala okuthintelayo
• Ukukhulelwa
• I-Sarcoidosis (ukuvuvukala kwee-lymph nodes, imiphunga, isibindi, amehlo, ulusu, okanye ezinye izicubu)
• Inkqubo ye lupus erythematosis
• Isifo sikaTurner

Iimpawu zinokubandakanya nayiphi na kwezi zinto zilandelayo:

• Intloko ebuhlungu, ukubetha, yonke imihla, ngokungaqhelekanga kunye nokubi kusasa
• Intlungu yomqala
• Umbono omfiliba
• Isandi sokubhuza ezindlebeni (tinnitus)
• Ukuba nesiyezi
• Umbono ophindwe kabini (idiplopia)
• Isicaphucaphu, ukugabha
• Iingxaki zombono ezinjengokudanyaza okanye ukulahleka kombono
• Intlungu ebuyela emva, ikhupha imilenze yomibini

Intloko inokuba mandundu ngexesha lomsebenzi, ngakumbi xa uqinisa izihlunu zesisu ngexesha lokukhohlela okanye lokucinezela.

Umboneleli wezempilo uya kwenza uvavanyo lomzimba. Iimpawu zale meko zibandakanya:

• Ukuqhaqha i-fontanelle yangaphandle kwiintsana
• Ukwandisa ubukhulu bentloko
• Ukudumba kwethambo le-optic ngasemva kweliso (papilledema)
• Ukujika kwangaphakathi kwamehlo empumlweni (i-cranial yesithandathu, okanye i-abducens, i-nerve palsy)

Nangona kukho uxinzelelo olwandileyo kwikakayi, akukho lutshintsho kulumko.

Uvavanyo olunokwenziwa lunokubandakanya:

• Uviwo lweFunduscopic
• Ukuvavanywa kwentloko kwe-CT
• Ukuhlolwa kwamehlo, kubandakanya ukuvavanywa kwendawo ebonakalayo
• I-MRI yentloko ene-MR venography
• Ukugqobhoza iLumbar (impompo yomqolo)

Uxilongo lwenziwa xa ezinye iimeko zempilo zikhutshelwa ngaphandle. Oku kubandakanya iimeko ezinokubangela ukwanda koxinzelelo kwikakayi, njenge:

• IHydrocephalus
• Ithumba
• Imithambo sinus thrombosis

Unyango lujolise kwisizathu sepseudotumor. Eyona njongo iphambili kunyango kukugcina umbono kunye nokunciphisa ubunzima beentloko.

Ukugqobhoza i-lumbar (impompo yomqolo) kunokunceda ukunciphisa uxinzelelo kwingqondo kunye nokuthintela iingxaki zombono. Ukuphindaphinda ii-lumbar punctures ziluncedo kubafazi abakhulelweyo ukuze bacothise utyando kude kube semva kokuhanjiswa.

Olunye unyango lunokubandakanya:

• Ukuthintela ulwelo okanye ityuwa
• Amayeza anjenge-corticosteroids, i-acetazolamide, i-furosemide, kunye ne-topiramate
• Iinkqubo zokurhola ukukhulula uxinzelelo kulwakhiwo lomqolo womqolo
• Utyando lokukhulula uxinzelelo kwi-optic nerve
• Ukuhla ukusinda
• Unyango lwezifo ezisisiseko, ezinje nge-vitamin A

Abantu baya kufuna ukuba umbono wabo ubekwe esweni. Kunokubakho ukulahleka kombono, ngamanye amaxesha okusisigxina. Ukulandelelwa kwe-MRI okanye i-CT scans kungenziwa ukukhupha iingxaki ezinjengezicubu okanye i-hydrocephalus (i-buildup of fluid ngaphakathi kwekhayi).

Ngamanye amaxesha, uxinzelelo ngaphakathi kwengqondo luhlala luphezulu iminyaka emininzi. Iimpawu zingabuya kwabanye abantu. Inani elincinci labantu baneempawu eziya zisiba mbi kwaye zikhokelele kubumfama.

Le meko ngamanye amaxesha iyanyamalala iyodwa kwisithuba seenyanga ezi-6. Iimpawu zingabuya kwabanye abantu. Inani elincinci labantu baneempawu eziya zisiba mbi kwaye zikhokelele kubumfama.

Ukuphulukana nombono yingxaki enkulu yale meko.

Tsalela umnikezeli wakho ukuba wena okanye umntwana wakho unazo naziphi na iimpawu ezidweliswe apha ngasentla.

Idiopathic intracranial uxinzelelo lwegazi; Ubuninzi bexinzelelo lwengqondo

• Inkqubo ye-nervous central kunye ne-peripheral system

UMiller NR. IPseudotumor cerebri. Ku: Winn HR, ed. Ugqirha we-Youmans kunye no-Winn Neurological. Umhla wesi-7. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 164.

IRosenberg GA. I-edema yobuchopho kunye nokuphazamiseka kokujikeleza kolwelo lwe-cerebrospinal. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ii-eds. I-Neurology kaBradley kwiKlinikhi yokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2016: isahl 88.

UVarma R, uWill SD. Neurology. Ku: Zitelli BJ, McIntire SC, Nowalk AJ, ii-eds. UZitelli no-Davis ’Atlas of Pediatric Physical Diagnosis. Umhla wesi-7. IPhiladelphia, PA: Elsevier, 2018: isahluko 16.