Ithumba lamatyhalarha eLeydig

Ithumba leseli leLeydig lithumba kumatyhalarha. Ikhula kwiiseli zeLeydig. Ezi ziiseli ezikumatyhalarha akhupha ihomoni eyindoda, i-testosterone.

Unobangela weli thumba awaziwa. Akukho bungozi baziwayo kweli thumba. Ngokungafaniyo ne-germ tumors yamatyhalarha, eli thumba alibonakali linxulunyaniswa novavanyo olungafunekiyo.

Izidumbu zeseli zeLeydig zenza inani elincinci kakhulu kuwo onke amathumba wamatyhalarha. Zifumaneka rhoqo kumadoda aphakathi kweminyaka engama-30 ukuya kwengama-60 ubudala. Eli thumba aliqhelekanga ebantwaneni ngaphambi kokufikisa, kodwa linokubangela ukufikisa kwangethuba.

Kungangabikho mpawu.

Xa iimpawu zenzeka, zinokubandakanya:

• Ukuphazamiseka okanye iintlungu kumatyhalarha
• Ukwandiswa kwamatyhalarha okanye ukutshintsha ngendlela evakalelwa ngayo
• Ukukhula okuthe kratya kwethishu yamabele (gynecomastia) - nangona kunjalo, oku kunokwenzeka ngesiqhelo kubafana abafikisayo abangenawo umhlaza wamatyhalarha.
• Ubunzima kwisikram
• Isigaqa okanye ukudumba nokuba liliphi ityhalarha
• Intlungu emazantsi esisu okanye ngasemva
• Ayikwazi ukuba notata abantwana (ukungachumi)

Iimpawu ezikwezinye iindawo zomzimba, ezinje ngemiphunga, isisu, isinqe, umqolo, okanye ingqondo zinokwenzeka ukuba umhlaza usasazekile.

Uvavanyo lomzimba luveza isigaxa esiqinileyo kwelinye lamatyhalarha. Xa umboneleli wezempilo ephethe isibane esifikelela kwisingxobo samatyhalarha, isibane asidluli kwiqhuma. Olu vavanyo lubizwa ngokuba kukuguqulwa komzimba.

Olunye uvavanyo lubandakanya:

• Uvavanyo lwegazi lwamanqaku ethumba: i-alpha fetoprotein (AFP), i-chorionic gonadotropin (beta HCG), kunye ne-lactate dehydrogenase (LDH)
• Ukuxilongwa kwe-CT kwesifuba, isisu kunye nesinqe ukujonga ukuba umhlaza usasazekile na
• I-Ultrasound yesingxobo samatyhalarha

Uvavanyo lwethishu luhlala lwenziwa emva kokuba lonke ityhalarha lisuswe ngotyando (orchiectomy).

Unyango lwethumba leseli leLeydig kuxhomekeke kwinqanaba lalo.

• Inqanaba I umhlaza awusasazekanga ngaphaya kwetyhalarha.
• Umhlaza weSigaba II usasazeke kwii-lymph node esiswini.
• Umhlaza weSigaba se-III usasazeke ngaphaya kwe-lymph node (ngokunokwenzeka ukuya kuthi ga kwisibindi, imiphunga, okanye ingqondo).

Utyando lwenziwa ukususa ityhalarha (orchiectomy). I-lymph node ezikufutshane nazo zingasuswa (i-lymphadenectomy).

I-Chemotherapy inokusetyenziselwa ukunyanga eli thumba. Njengoko amathumba eseli eLeydig enqabile, olu nyango alukhange lufundwe njengonyango kwezinye, umhlaza wamatyhalarha oqhelekileyo.

Ukujoyina iqela lenkxaso apho amalungu abelana ngamava aqhelekileyo kunye neengxaki kunokuhlala kunceda ukunciphisa uxinzelelo lokugula.

Umhlaza wamatyhalarha yenye yezona zomhlaza zinokunyangeka kwaye ziyanyangeka. Imbonakalo imbi kakhulu ukuba ithumba alifumaneki kwangethuba.

Umhlaza unganwenwela nakwamanye amalungu omzimba. Ezona ndawo zixhaphakileyo zibandakanya:

• Isisu
• Amaphaphu
• Indawo ye-Retroperitoneal (indawo ekufuphi nezintso ngasemva kwamanye amalungu akwindawo esiswini)
• Umqolo

Iingxaki zoqhaqho zingabandakanya:

• Ukopha kunye nosulelo
• Ukungachumi (ukuba omabini amasende ayasuswa)

Ukuba uneminyaka yobudala bokuzala, cela umboneleli wakho malunga neendlela zokugcina isidoda sakho ukuze sisetyenziswe kamva.

Tsalela umnikezeli wakho ukuba unempawu zomhlaza wamatyhalarha.

Ukwenza uvavanyo lokuzivavanya (TSE) inyanga nenyanga kunokunceda ekufumaneni umhlaza wamatyhalarhume kwangoko, ngaphambi kokuba usasazeke. Ukufumana umhlaza wamatyhalarha kwangoko kubalulekile kunyango olusebenzayo kunye nokusinda.

Ithumba - iseli yeLeydig; Ithumba lesende - iLeydig

• I-anatomy yokuzala eyindoda

UFriedlander TW, umhlaza omncinci u-Testicular. Ku: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, ii-eds. I-Oncology yeklinikhi yase-Abeloff. Umhla wesi-6. IPhiladelphia, PA: Elsevier; 2020: isahl. 83.

Kwiwebhusayithi yeZiko loMhlaza weSizwe. Unyango lomhlaza wamatyhalarha (PDQ) -uhlobo lobungcali kwezempilo. www.cancer.gov/types/testicular/hp/unyango-zonyango-pdq. Ukuhlaziywa ngoMeyi 21, 2020. Ifikeleleke ngoJulayi 21, 2020.

UStephenson AJ, uGilligan TD. Neoplasms yamatyhalarha. Ku: UPartin AW, uDmochowski RR, uKavoussi LR, uPeter CA, ii-eds. ICampbell-Walsh-Wein Urology. Umhla we-12. IPhiladelphia, PA: Elsevier; 2021: isahluko 76.