Isifo samathambo

I-Psoriatic arthritis yingxaki edibeneyo (i-arthritis) edla ngokwenzeka kwimeko yesikhumba ebizwa ngokuba yi-psoriasis.

I-Psoriasis yingxaki eqhelekileyo yolusu ebangela amabala abomvu kulusu. Yimeko eqhubekayo (engapheliyo) yokuvuvukala. I-Psoriatic arthritis ivela malunga neepesenti ezingama-7 ukuya kuma-42% abantu abane-psoriasis. I-Nail psoriasis inxulunyaniswa ne-psoriatic arthritis.

Kwiimeko ezininzi, i-psoriasis iza ngaphambi kwesifo samathambo. Kubantu abambalwa, isifo samathambo siza ngaphambi kwesifo solusu. Nangona kunjalo, ukuba ne-psoriasis ebanzi, esasazekayo kubonakala ngathi kwandisa ithuba lokufumana isifo samathambo.

Unobangela we-psoriatic arthritis awaziwa. Imfuza, amajoni omzimba, kunye nezinto zokusingqongileyo zinokudlala indima. Kusenokwenzeka ukuba ulusu kunye nezifo ezidibeneyo zinokuba nezizathu ezifanayo. Nangona kunjalo, zingenakwenzeka kunye.

Isifo samathambo sinokuthamba kwaye sibandakanye kuphela amalungu ambalwa. Amalungu ekupheleni kweminwe okanye iinzwane anokuchaphazeleka ngakumbi. I-Psoriatic arthritis ihlala ingalinganiyo ibangela isifo samathambo kwelinye icala lomzimba.

Kwabanye abantu, esi sifo sinokuqatha kwaye sichaphazele amalungu amaninzi, kubandakanya nomqolo. Iimpawu ezisemqolo zibandakanya ukuqina kunye nentlungu. Zihlala zivela kumqolo ongezantsi kunye ne-sacrum.

Abanye abantu abane-psoriatic arthritis banokudumba kwamehlo.

Uninzi lwexesha, abantu abane-psoriatic arthritis banolusu kunye notshintsho olwenzipho kwi-psoriasis. Rhoqo, ulusu luba mandundu ngaxeshanye nesifo samathambo.

Iitendon zinokutsha yi-psoriatic arthritis. Imizekelo ibandakanya i-Achilles tendon, i-plantar fascia, kunye ne-tendon sheath esandleni.

Ngexesha lovavanyo lomzimba, umboneleli wezempilo uya kukhangela:

• Ukudumba ngokudibeneyo
• Amabala esikhumba (i-psoriasis) kunye neeping kwizikhonkwane
• Ukuthantamisa
• Ukudumba emehlweni

Ukudityaniswa kweX-reyi kunokwenziwa.

Akukho luvavanyo lwegazi luthile kwi-psoriatic arthritis okanye i-psoriasis. Uvavanyo lokulawula ezinye iintlobo zesifo samathambo lunokwenziwa:

• Into yeRheumatoid
• Amachiza omzimba alwa neCCP

Umboneleli angavavanya uhlobo olubizwa ngokuba yi-HLA-B27 Abantu ababandakanyeka ngasemva kunokwenzeka ukuba babe ne-HLA-B27.

Umboneleli wakho unokunika ii-nonsteroidal anti-inflammatory drug (NSAIDs) ukunciphisa iintlungu kunye nokudumba kwamalungu.

Isifo samathambo esingaphuculiyo kwii-NSAIDs ziya kufuna ukunyangwa ngamayeza abizwa ngokuba sisifo esiguqula amachiza e-antirheumatic (DMARDs). Oku kubandakanya:

• Imethotrexate
• I-Leflunomide
• Isulfasalazine

Iapremilast lelinye iyeza elisetyenziselwa unyango lwe-psoriatic arthritis.

Amayeza amatsha e-biologic ayasebenza kwi-psoriatic arthritis engahambelaniyo nee-DMARD. La mayeza athintela iprotein ebizwa ngokuba yi-tumor necrosis factor (TNF). Zihlala ziluncedo kwisifo solusu kunye nesifo esidibeneyo se-psoriatic arthritis. La mayeza anikezelwa ngenaliti.

Amanye amayeza amatsha e-biologic ayafumaneka ukunyanga i-psoriatic arthritis eqhubayo nangokusebenzisa ii-DMARD okanye ii-anti-TNF agents. La mayeza anikwa ngenaliti.

Amalungu abuhlungu kakhulu anokunyangwa ngenaliti ye-steroid. Oku kusetyenziswa xa inye kuphela okanye amalungu ambalwa ebandakanyekayo. Uninzi lweengcali alucebisi ngomlomo i-corticosteroids ye-psoriatic arthritis. Ukusetyenziswa kwabo kunokuba mandundu kwi-psoriasis kwaye kuphazamise ukusebenza kwamanye amachiza.

Kwiimeko ezinqabileyo, utyando lunokufuneka ukuze kulungiswe okanye kutshintshwe amalungu adibeneyo.

Abantu abanokudumba kwamehlo kufuneka babone ugqirha wamehlo.

Umboneleli wakho unokucebisa ngokudibanisa ukuphumla kunye nokuzilolonga. Unyango lomzimba lunokunceda ukwandisa intshukumo edibeneyo. Unokusebenzisa ubushushu kunye nonyango olubandayo.

Esi sifo ngamanye amaxesha sithambile kwaye sichaphazela kuphela amalungu ambalwa. Nangona kunjalo, kubantu abaninzi abanomonakalo we-psoriatic arthritis kumalungu ayenzeka kwiminyaka eliqela yokuqala. Kwabanye abantu, isifo samathambo esibi kakhulu sinokubangela iziphene ezandleni, ezinyaweni nasemqolo.

Uninzi lwabantu abane-psoriatic arthritis abangaphuculiyo nge-NSAIDs kufuneka babone i-rheumatologist, ingcali kwi-arthritis, kunye nedermatologist ye-psoriasis.

Unyango lwakwangoko lunokuthomalalisa iintlungu kunye nokuthintela ukonzakala ngokudibeneyo, nokuba kunjani na.

Tsalela umnikezeli wakho ukuba uhlakulela iimpawu zesifo samathambo kunye ne-psoriasis.

Isifo samathambo - psoriatic; Psoriasis - psoriatic samathambo; Spondyloarthritis - isifo samathambo; I-PsA

• I-Psoriasis - i-guttate kwiingalo nasesifubeni
• I-Psoriasis - i-guttate esidleleni

IBruce IN, Ho PYP. Iimpawu zonyango lwe-psoriatic arthritis. Ku: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, ii-eds. Rheumatology. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2019: isahluko 128.

UGladman D, uRigby W, uAzevedo VF, et al. I-Tofacitinib ye-psoriatic arthritis kwizigulana ezinempendulo engonelanga kwii-inhibitors ze-TNF. N Engl J Med. 2017; 377:1525-1536.

USmolen JS, uSchöls M, uBraun J, et al. Ukunyanga i-axial spondyloarthritis kunye ne-peripheral spondyloarthritis, ngakumbi i-psoriatic arthritis, ukujolisa: Uhlaziyo luka-2017 lweengcebiso ngumbutho wamazwe aphesheya. U-Ann Rheum Dis. 2018; 77 (1): 3-17. IINKCUKACHA: 28684559 pubmed.ncbi.nlm.nih.gov/28684559/.

Veale DJ, Orr C.Ulawulo lwe-psoriatic arthritis. Ku: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, ii-eds. Rheumatology. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2019: isahluko 131.