Lupus nephritis

I-Lupus nephritis, esisifo sezintso, sisisombululo se-systemic lupus erythematosus.

Inkqubo ye-lupus erythematosus (i-SLE, okanye i-lupus) sisifo esizenzekelayo. Oku kuthetha ukuba kukho ingxaki kumasosha omzimba.

Ngokwesiqhelo, amajoni omzimba anceda ukukhusela umzimba kukosuleleko okanye kwinto eyingozi. Kodwa kubantu abanesifo sokuzimela, amajoni omzimba awakwazi ukwahlula phakathi kwezinto eziyingozi kunye nezisempilweni. Ngenxa yoko, amajoni omzimba ahlasela ezinye iiseli kunye nezicubu ezisempilweni.

SLE ingonakalisa iindawo ezahlukeneyo zezintso. Oku kunokukhokelela kwiziphazamiso ezinje:

• I-nephritis yangaphakathi
• Isifo seNephrotic
• Isikhumba glomerulonephritis
• Ukungaphumeleli kwezintso

Iimpawu ze-lupus nephritis zibandakanya:

• Igazi kumchamo
• Ukubonakala kwegwebu kumchamo
• Ukudumba (i-edema) yayo nayiphi na indawo yomzimba
• Igazi elonyukayo

Umboneleli wezempilo uya kwenza uvavanyo lomzimba kwaye abuze malunga neempawu zakho. Izandi ezingaqhelekanga zinokuviwa xa umboneleli emamele intliziyo yakho kunye nemiphunga.

Uvavanyo olunokwenziwa lunokubandakanya:

• Isihloko se-ANA
• BUN kunye ne-creatinine
• Gcwalisa amanqanaba
• Uhlalutyo lomchamo
• Umchamo protein
• Isifo sezintso, ukumisela unyango olufanelekileyo

Injongo yonyango kukuphucula ukusebenza kwezintso kunye nokulibazisa ukusilela kwezintso.

Amayeza anokubandakanya amayeza acinezela amajoni omzimba, anje ngecorticosteroids, cyclophosphamide, mycophenolate mofetil, okanye azathioprine.

Unokufuna i-dialysis ukulawula iimpawu zokungaphumeleli kwezintso, ngamanye amaxesha okwexeshana. Ukufakelwa kwezintso kunokucetyiswa. Abantu abane-lupus esebenzayo akufuneki batshintshwe kuba imeko inokwenzeka kwizintso ezifakiweyo.

Wenza kakuhle kangakanani, kuxhomekeke kwifom ethile ye-lupus nephritis. Unokuba ne-flare-ups, kunye namaxesha xa ungenazo iimpawu.

Abanye abantu abakule meko bakhula ukusilela kwezintso ixesha elide (ezingapheliyo).

Nangona i-lupus nephritis inokubuyela kwizintso ezifakiweyo, kunqabile ukuba ikhokelele kwisifo sezintso.

Iingxaki ezinokubangelwa yi-lupus nephritis zibandakanya:

• Ukungasebenzi kakuhle kwezintso
• Ukusilela okungapheliyo kwezintso

Biza umboneleli wakho ukuba unegazi kumchamo wakho okanye ukudumba komzimba wakho.

Ukuba une-lupus nephritis, tsalela umnikezeli wakho ukuba uqaphela ukwehla kwemveliso yomchamo.

Ukunyanga i-lupus kunokunceda ukuthintela okanye ukulibazisa ukuqala kwe-lupus nephritis.

Nephritis - lupus; Isifo seLupus glomerular

• I-anatomy yezintso

UHahn BH, uMcMahon M, uWilkinson A, et al. Ikholeji yaseMelika yeRheumatology izikhokelo zovavanyo, inkcazo yamatyala, unyango kunye nolawulo lwe-lupus nephritis. Ukunyamekelwa kweArthritis Res (Hoboken). Ngo-2012; 64 (6): 797-808. I-PMCID: 3437757 www.ncbi.nlm.nih.gov/pmc/articles/PMC3437757.

UWadhwani S, uJayne D, uRovin BH. Lupus nephritis. Ku: Feehally J, Floege J, Tonelli M, Johnson RJ, ii-eds. I-Clinical Nephrology epheleleyo. Umhla wesi-6. IPhiladelphia, PA: Elsevier; I-2019: isahluko 26.