I-thrombocytopenia ebangelwa ziziyobisi

I-Thrombocytopenia yiyo nayiphi na ingxaki ekungabikho kuyo iiplatelets ezaneleyo. Iiplatelets iiseli ezisegazini ezinceda i-clot yegazi. Inani eliphantsi leplatelet lenza ukopha ngakumbi.

Xa amayeza okanye iziyobisi zingunobangela wenani eliphantsi leplatelet, ibizwa ngokuba yitrombocytopenia ebangelwa ziziyobisi.

I-thrombocytopenia ebangelwa ziziyobisi yenzeka xa amayeza athile etshabalalisa iiplatelet okanye ephazamisa amandla omzimba okwenza ngokwaneleyo.

Zimbini iintlobo ze-thrombocytopenia eyenziwe ngamachiza: ama-immune kunye ne-nonimmune.

Ukuba iyeza libangela ukuba umzimba wakho uvelise izilwa-buhlungu, ezifuna zize zitshabalalise iiplatelets zakho, imeko leyo ibizwa ngokuba ngamachiza athintela ukoyikiswa kwezifo. IHeparin, igazi elincinci, sesona sizathu sixhaphakileyo se-immune thrombocytopenia.

Ukuba iyeza lithintela umongo wethambo lakho ekwenzeni iiplatelets ezaneleyo, imeko ibizwa ngokuba yi-non-immune thrombocytopenia. Amachiza e-Chemotherapy kunye neyeza lokuthimba elibizwa ngokuba yi-valproic acid linokukhokelela kule ngxaki.

Amanye amayeza abangela i-thrombocytopenia ebangelwa ziziyobisi ibandakanya:

• Furosemide
• Igolide, esetyenziselwa ukunyanga isifo samathambo
• Izidakamizwa ezichasayo ezichasayo (i-NSAID)
• IPenicillin
• Iquinidine
• Iquinine
• Iranididine
• Isulfonamides
• I-Linezolid kunye nezinye i-antibiotics
• Iingxelo

Ukuhla kweeplatelet kunokubangela:

• Ukopha ngokungaqhelekanga
• Ukopha xa uhlamba amazinyo
• Ukutyumza okulula
• Khomba amabala abomvu eluswini (petechiae)

Inyathelo lokuqala kukuyeka ukusebenzisa iyeza elibangela ingxaki.

Kubantu abanegazi elisongela ubomi, unyango lunokubandakanya:

• Unyango lwe-Immunoglobulin (IVIG) olunikezwe ngomthambo
• Utshintshiselwano lwePlasma (plasmapheresis)
• Ukufakwa kwegazi kwiPlatelet
• Iyeza leCorticosteroid

Ukopha kungasongela ubomi ukuba kwenzeka engqondweni okanye kwamanye amalungu.

Umfazi okhulelweyo onee-antibodies kwiiplatelets unokugqithisela ii-antibodies kusana olusesibelekweni.

Fowunela umboneleli wakho wezempilo ukuba ukopha ngokungachazwanga okanye utyumkile kwaye uthatha amayeza, anje ngala achazwe apha ngasentla phantsi koNobangela.

I-thrombocytopenia ebangelwa ziziyobisi; I-immune thrombocytopenia - iziyobisi

• Ukubumba kwegazi
• Amahlwili egazi

Abrams CS. I-Thrombocytopenia. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahluko 172.

IWarkentin TE. I-Thrombocytopenia ebangelwa yintshabalalo yeplatelet, hypersplenism, okanye ihemodilution. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ii-eds. I-Hematology: Imigaqo esisiseko kunye nokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 132.