Hyperensensitivity vasculitis

Hypersensitivity vasculitis kukusabela gwenxa kwichiza, usulelo, okanye into yangaphandle. Kukhokelela kukudumba kunye nomonakalo kwimithambo yegazi, ngakumbi kulusu. Eli gama alisetyenziswanga kakhulu okwangoku kuba amagama athile acingelwa ukuba achanekile.

I-Hypersensitivity vasculitis, okanye i-vasculitis encinci yenqanawa encinci, ibangelwa ngu:

• Ukungaziphathi kakuhle kwichiza okanye kwenye into yangaphandle
• Impendulo kusulelo

Ihlala ichaphazela abantu abadala kuneminyaka eyi-16.

Rhoqo, unobangela wengxaki awufumaneki nokuba kufundwe ngononophelo kwimbali yezonyango.

I-Hypersensitivity vasculitis inokubonakala ngathi yinkqubo, i-necrotizing vasculitis, enokuthi ichaphazele imithambo yegazi emzimbeni wonke hayi kulusu kuphela. Kubantwana, inokujongeka njenge-Henoch-Schonlein purpura.

Iimpawu zingabandakanya:

• Irhashalala elitsha elinethenda, mfusa okanye bumdaka ngebala kwiindawo ezinkulu
• Izilonda zolusu ubukhulu becala zibekwe emilenzeni, ezinqeni, okanye esiqwini
• Amadyungudyungu kulusu
• Imihlathi (urticaria), inokuhlala ngaphezulu kweeyure ezingama-24
• Izilonda ezivulekileyo ezinezicubu ezifileyo (izilonda ezingabalulekanga)

Umboneleli wezempilo uya kuseka isifo kwiimpawu. Umboneleli uya kujonga kwakhona nawaphi na amayeza okanye iziyobisi ozithathileyo kunye nosulelo lwamva nje. Uya kubuzwa malunga nokukhohlela, umkhuhlane, okanye iintlungu esifubeni.

Kuya kwenziwa uvavanyo olupheleleyo lomzimba.

Uvavanyo lwegazi kunye nomchamo lunokwenziwa ukujonga ukuphazamiseka kwenkqubo efana ne-systemic lupus erythematosus, dermatomyositis, okanye hepatitis C. Uvavanyo lwegazi lunokubandakanya:

• Gcwalisa ubalo lwegazi ngokwahluka
• Inqanaba le-sedimentation ye-Erythrocyte
• Iphaneli yeKhemistry ene-enzyme zesibindi kunye ne-creatinine
• Intsholongwane yentsholongwane (ANA)
• Into yeRheumatoid
• Antineutrophil cytoplasmic antibodies (ANCA)
• Gcwalisa amanqanaba
• Cryoglobulins
• Uvavanyo lwe-Hepatitis B kunye no-C
• Uvavanyo lwe-HIV
• Uhlalutyo lomchamo

Ulusu lwe-biopsy lubonisa ukudumba kwemithambo yegazi encinci.

Injongo yonyango kukunciphisa ukudumba.

Umboneleli wakho unokumisela i-aspirin, i-nonsteroidal anti-inflammatory drug (NSAIDs), okanye i-corticosteroids ukunciphisa ukudumba kwemithambo yegazi. (MUSA ukunika iasprini ebantwaneni ngaphandle kwaxa kucetyiswa ngumboneleli wakho).

Umboneleli wakho uya kukuxelela ukuba uyeke ukuthatha amayeza anokubangela le meko.

Hypersensitivity vasculitis ihlala ihamba ngokuhamba kwexesha. Le meko inokubuyela kwabanye abantu.

Abantu abane-vasculitis eqhubekayo kufuneka bahlolwe i-vasculitis yenkqubo.

Iingxaki zinokubandakanya:

• Umonakalo ongapheliyo kwimithambo yegazi okanye ulusu olunezikrelemnqa
• Imithambo yegazi edumbileyo echaphazela amalungu angaphakathi

Tsalela umnxeba umboneleli wakho ukuba uneempawu ze-hypersensitivity vasculitis.

SUKUTHABATHA amayeza athe abangela ukungahambelani nezinto ezidlulileyo.

I-vasculitis encinci yenqanawa encinci; Isifo semithambo yegazi; I-leukocytoclastic vasculitis

• I-Vasculitis entendeni
• I-Vasculitis
• I-Vasculitis - i-urticarial esandleni

IHabif TP. Hypersensitivity syndromes kunye ne-vasculitis. Ku: Habif TP, ed. Zonyango lwezonyango. Umhla wesi-6. IPhiladelphia, PA: Elsevier; 2016: isahl 18.

UJennette JC, Falk RJ, Bacon PA, et al. I-2012 ehlaziyiweyo yengqungquthela yesivumelwano seChapel Hill yesivumelwano se-vasculitides. Isifo samathambo Rheum. Ngo-2013; 65 (1): 1-11. IINKCUKACHA: 23045170 www.ncbi.nlm.nih.gov/pubmed/23045170.

IPatterson JW. Ipateni yokuphendula ye-vasculopathic. Ku: Patterson JW, ed. Weedon's Ulusu lwezifo. Ngomhla we-4. IPhiladelphia, PA: Elsevier Churchill Livingstone; 2016: isahl 8.

Ilitye JH. Inkqubo ye-vasculitides. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 270.

ISunderkötter CH, uZelger B, uChen KR, et al. Ukuchazwa kwegama kwe-vasculitis enqamlezileyo: isihlomelo sedermatologic kwiNgqungquthela yoVumelwano yeHlabathi yeHlabathi yokuHlaziya yeHlabathi ye-Chapel ka-2012 yokuchongwa kweVasculitides. Isifo samathambo Rheumatol. 2018; 70 (2): 171-184. IINKCUKACHA: 29136340 www.ncbi.nlm.nih.gov/pubmed/29136340.