Igranulocytosis

Amaseli egazi amhlophe alwa nosulelo olusuka kwintsholongwane, intsholongwane, ukungunda kunye nezinye iintsholongwane. Olunye uhlobo olubalulekileyo lweeseli ezimhlophe zegazi yigranulocyte, eyenziwe kumongo wethambo kwaye ihamba egazini emzimbeni wonke. Iigranulocytes zibona usulelo, ziqokelelelene kwiindawo zosulelo, kwaye zitshabalalise iintsholongwane.

Xa umzimba uneembumbulu ezimbalwa kakhulu, imeko ibizwa ngokuba yi-agranulocytosis. Oku kwenza ukuba kube nzima kumzimba ukulwa neentsholongwane. Ngenxa yoko, umntu kungenzeka ukuba agule kwizifo.

I-Agranulocytosis inokubangelwa ngu:

• Ukuphazamiseka ngokuzenzekelayo
• Izifo zomongo wethambo, ezinje nge-myelodysplasia okanye i-granular lymphocyte (LGL) leukemia
• Amayeza athile asetyenziselwa ukunyanga izifo, kubandakanya umhlaza
• Ezinye iziyobisi ezitalatweni
• Ukungondleki
• Ukulungiselela ukufakelwa komongo wethambo
• Ingxaki ngemfuza

Iimpawu zale meko zinokubandakanya:

• Ifiva
• Ukugodola
• UMalaise
• Ubuthathaka ngokubanzi
• Umqala obuhkungu
• Izilonda zomlomo nezomqala
• Intlungu yethambo
• Ukukrala kwemiphunga
• Umothuko

Kuya kwenziwa uvavanyo lokwahluka kwegazi ukulinganisa ipesenti yohlobo ngalunye lweseli emhlophe egazini.

Olunye uvavanyo lokuchonga imeko lunokubandakanya:

• Umongo wethambo
• Isifo sesilonda somlomo
• Izifundo ze-Neutrophil antibody (uvavanyo lwegazi)

Unyango luxhomekeke kwisibalo senani eliphantsi leeseli ezimhlophe zegazi. Umzekelo, ukuba iyeza lingunobangela, ukuyeka okanye ukutshintsha uye kwelinye iyeza kunokunceda. Ngamanye amaxesha, amayeza anceda umzimba ukuba wenze iiseli ezimhlophe zegazi aya kusetyenziswa.

Ukunyanga okanye ukususa unobangela kuhlala kukhokelela kwisiphumo esihle.

Ukuba ufumana unyango okanye uthatha amayeza anokubangela i-agranulocytosis, umboneleli wakho wezempilo uya kusebenzisa uvavanyo lwegazi ukukujonga.

IGranulocytopenia; IGranulopenia

• Iiseli zegazi

Ukupheka JR. Ii-syndromes zokungaphumeleli komongo wethambo. Ku: Hsi ED, ed. IHematopathology. Ngomhla wesi-3. IPhiladelphia, PA: Elsevier; I-2018: isahluko 5.

IKlokkevold PR, uMealey BL. Impembelelo yeemeko zenkqubo. Ku: Newman MG, Takei HH, Klokkevold PR, Carranza FA, ii-eds. INewman kunye neCarranza's Clinical Periodontology. Umhla we-13. IPhiladelphia, PA: Elsevier; I-2019: isahluko 14.

Sive J, Foggo V. Isifo se-Haematological. Ku: Intsiba A, uRandall D, indlu yamanzi M, ii-eds. Kumar kunye noClke's Clinical Medicine. Ngomhla we-10. IPhiladelphia, PA: Elsevier; 2021: isahluko 17.