Ngobungqina

I-Ganglioneuroblastoma sisisu esiphakathi esivela kwizihlunu zemithambo-luvo. I-tumor ephakathi iphakathi kwe-benign (ukukhula ngokukhawuleza kwaye akunakwenzeka ukuba isasazeke) kunye nokulimala (ukukhula ngokukhawuleza, ukukrakra, kunye nokusabalalisa).

I-Ganglioneuroblastoma ubukhulu becala ivela kubantwana abaneminyaka emi-2 ukuya kwemi-4 ubudala. Ithumba lichaphazela amakhwenkwe namantombazana ngokulinganayo. Oku kwenzeka kunqabile kubantu abadala. Ukudumba kwenkqubo yemithambo-luvo kunamaqondo awahlukileyo okwahlulahlula. Oku kusekwe kwindlela iiseli zesisu ezijongeka ngayo phantsi kwemicroscope. Inokuxela kwangaphambili ukuba iya kusasazeka na okanye hayi.

Iimvumi zeBenign azikwazi ukusasazeka. Amathumba amabi anobundlobongela, akhula ngokukhawuleza, kwaye ahlala esasazeka. I-ganglioneuroma ayibi bubi kwindalo. I-neuroblastoma (eyenzeka kubantwana abangaphezu konyaka omnye ubudala) ihlala iyingozi.

I-ganglioneuroblastoma inokuba kwindawo enye kuphela okanye inokuthi ixhaphake, kodwa ihlala inoburhalarhume kune-neuroblastoma. Unobangela awaziwa.

Eyona nto iqhelekileyo, isigaqa sinokuviwa esiswini kunye nokuthamba.

Esi sifo sinokubakho nakwezinye iisayithi, kubandakanya:

• Isifuba
• Intamo
• Imilenze

Umboneleli wezempilo angenza ezi mvavanyo zilandelayo:

• Umnqweno wenaliti entle yethumba
• Umnqweno wethambo lomnqweno kunye ne-biopsy
• Ukuskena amathambo
• Ukuvavanywa kwe-CT okanye ukuskena kweMRI kwendawo echaphazelekayo
• Ukuskena iPET
• Iskena seMetaiodobenzylguanidine (MIBG)
• Uvavanyo olukhethekileyo lwegazi kunye nomchamo
• Utyando lwe-biopsy ukuqinisekisa isifo

Kuxhomekeka kuhlobo lwethumba, unyango lunokubandakanya utyando, kwaye kunokwenzeka ukuba unyango lwe-chemotherapy kunye nonyango lwemitha.

Ngenxa yokuba la mathumba anqabile, kufuneka anyangwe kwiziko elikhethekileyo ziingcali ezinamava ngazo.

Imibutho enika inkxaso kunye nolwazi olongezelelweyo:

• Iqela le-Oncology yaBantwana - www.childrensoncologygroup.org
• Umbutho womhlaza wabantwana weNeuroblastoma-www.neuroblastomacancer.org

Umbono uxhomekeke ekubeni i-tumor isasazeke kangakanani, kwaye nokuba ezinye iindawo zethumba ziqulathe iiseli zomhlaza ezinobundlongondlongo.

Iingxaki ezinokubangela zibandakanya:

• Iingxaki zoqhaqho, imitha, okanye ichemotherapy
• Ukusasazeka kwethumba kwiindawo ezingqongileyo

Fowunela umboneleli wakho ukuba uziva unamaqhuma okanye ukukhula emzimbeni womntwana wakho. Qinisekisa ukuba abantwana bafumana iimviwo zesiqhelo njengenxalenye yokhathalelo lwabantwana.

IHarrison DJ, iAter JL. Neuroblastoma. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, ii-eds. Incwadi kaNelson yeNcwadi yePediatrics. Umhla wama-21. IPhiladelphia, PA: Elsevier; 2020: isahl 525.

IMyers JL. Mediastinum. Ku: Goldblum JR, Izibane LW, McKenney JK, Myers JL, eds. Rosai kunye neAckerman's Pathology. Ngomhla we-11. IPhiladelphia, PA: Elsevier; I-2018: isahluko 12.