Urticaria pigmentosa

I-Urticaria pigmentosa sisifo solusu esivelisa ulusu olumnyama kunye nokurhawuzelela okubi kakhulu. Amatsili anokukhula xa ezi ndawo zolusu zikhuhla.

I-Urticaria pigmentosa yenzeka xa kukho iiseli ezininzi zokukrala (iiseli zemasti) kulusu. Iiseli ezincinci ziiseli zomzimba zokuzikhusela ezinceda umzimba ukulwa izifo. Iiseli Mast zenza kwaye zikhuphe i-histamine, ebangela ukuba izicwili ezikufutshane zidumbe kwaye zitshise.

Izinto ezinokubangela ukukhutshwa kwe-histamine kunye neempawu zesikhumba zibandakanya:

• Ukuhlikihla ulusu
• Usulelo
• Zilolonge
• Ukusela ulwelo olushushu, ukutya ukutya okunezipayisi
• Ukukhanya kwelanga, ukubonakaliswa yingqele
• Amayeza, anje nge-aspirin okanye ezinye ii-NSAID, ikhodine, i-morphine, idayi ye-x-ray, amanye amayeza e-anesthesia, utywala

I-Urticaria pigmentosa ixhaphake kakhulu kubantwana. Inokwenzeka nakwabantu abadala.

Uphawu oluphambili ngamabala amdaka eluswini. Ezi patches ziqulathe iiseli ezibizwa ngokuba yimastocyte. Xa ii-mastocyte zikhupha i-histamine yemichiza, ii-patches zikhula zibe ngamaqhuqhuva afana nomqala. Abantwana abancinci banokuphuhlisa i-blister ezele lulwelo xa ukubhuqa kukrwelekile.

Ubuso bunokubomvu ngokukhawuleza.

Kwiimeko ezinzima, ezi mpawu zinokwenzeka:

• Urhudo
• Ukuphelelwa ngamandla (ngokungaqhelekanga)
• Intloko ebuhlungu
• Ngqisha
• Ukubetha kwentliziyo okukhawulezayo

Umboneleli wezempilo uya kuvavanya ulusu. Umboneleli unokukrokrela i-urticarial pigmentosa xa isikhumba sihlikihliwe kwaye siphakamise amaqhuma. Oku kubizwa ngokuba ngumqondiso weDarier.

Uvavanyo lokujonga le meko zezi:

• Ulusu lwe-biopsy ukukhangela inani eliphezulu leeseli zemasti
• Umchamo we-histamine
• Uvavanyo lwegazi ngokubalwa kweeseli zegazi kunye namanqanaba e-tryptase yegazi (i-tryptase yi-enzyme efumaneka kwiiseli zemasti)

Amayeza e-Antihistamine anokunceda ekunciphiseni iimpawu ezinjengokurhawuzelela nokugungxula. Thetha nomboneleli wakho malunga naluphi uhlobo lwe-antihistamine oyisebenzisayo. I-Corticosteroids efakwe kulusu kunye nonyango olulula lunokusetyenziswa kwezinye iimeko.

Umboneleli wakho unokumisela ezinye iintlobo zamayeza ukunyanga iimpawu zeendlela ezinobuzaza nezingaqhelekanga ze-urticaria pigmentosa.

I-Urticaria pigmentosa iyahamba ngokufikisa malunga nesiqingatha sabantwana abachaphazelekayo. Iimpawu zihlala zibangcono kwabanye njengoko bekhula bebadala.

Kubantu abadala, i-urticaria pigmentosa ingakhokelela kwinkqubo ye-mastocytosis. Le yimeko enzulu enokuchaphazela amathambo, ingqondo, imithambo-luvo, kunye nenkqubo yokwetyisa.

Ezona ngxaki ziphambili kukungonwabi xa urhawuzelela kunye nenkxalabo malunga nokubonakala kwamabala. Ezinye iingxaki ezinjengorhudo nokuphelelwa ngamandla kunqabile.

Ukutshatyalaliswa kwezinambuzane kunokubangela ukuphendula kakubi kubantu abane-urticaria pigmentosa. Buza umboneleli wakho ukuba kufuneka uphathe i-epinephrine kit oyisebenzisayo xa ufumana inyosi.

Tsalela umnikezeli wakho ukuba ubona iimpawu ze-urticaria pigmentosa.

Imastocytosis; Imastocytoma

• I-Urticaria pigmentosa ekhwapheni
• I-Mastocytosis - isasazeka ngokusikwa
• Urticaria pigmentosa esifubeni
• Urticaria pigmentosa - kufutshane

I-Chapman MS. Urticaria. Ku: Habif TP, Dinulos JGH, Chapman MS, Zug KA, ii-eds. Izifo zolusu: Ukuchonga nokunyanga. Ngomhla we-4. IPhiladelphia, PA: Elsevier; I-2018: isahluko 3.

U-Chen D, uGeorge TI. Imastocytosis. Ku: Hsi ED, ed. IHematopathology. Ngomhla wesi-3. IPhiladelphia, PA: Elsevier; I-2018: isahluko 20.

IPaige DG, iWakelin SH. Isifo solusu. Ku: Kumar P, Clark M, ii-eds. Kumar kunye noClke's Clinical Medicine. Umhla we-9. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 31.