Troponin: yintoni uvavanyo kwaye yintoni umphumo

Umxholo

• Ulwenza nini uvavanyo
• Oko kuthethwa sisiphumo

Uvavanyo lwe-troponin lwenziwa ukuvavanya isixa se-troponin T kunye ne-troponin I Iiproteni egazini, ezikhutshwa xa kukho ukwenzakala kwentliziyo yemisipha, njengaxa kukho isifo sentliziyo, umzekelo. Okukhulu ukonakala kwentliziyo, kokukhona isixa esikhulu kwezi proteni zisegazini.

Ke, kubantu abasempilweni, uvavanyo lwe-troponin aluchongi ubukho bezi proteni egazini, zithathwa njengesiphumo esibi. Amaxabiso aqhelekileyo etroponin egazini zezi:

• ITroponin T: 0.0 ukuya ku-0.04 ng / mL
• I-Troponin I: 0.0 ukuya ku-0.1 ng / mL

Ngamanye amaxesha, olu vavanyo lunoku-odolwa kunye nolunye uvavanyo lwegazi, njengokulinganisa kwe-myoglobin okanye i-creatine phosphokinase (CPK). Qonda ukuba yintoni uvavanyo lwe-CPK.

Uvavanyo lwenziwa kwisampulu yegazi ethunyelwa elebhu ukuyohlolwa. Olu hlobo lohlalutyo lweklinikhi, akukho lungiselelo luyimfuneko, njengokuzila ukutya okanye ukuthintela amayeza.

Ulwenza nini uvavanyo

Olu vavanyo luhlala lu-odolwa ngugqirha xa kukho urhano lokuba isifo sentliziyo senzekile, njengaxa iimpawu ezinje ngesifuba esibuhlungu, ukuphefumla nzima okanye ukurhawuzelela ingalo yasekhohlo, umzekelo. Kule meko, uvavanyo luphinda luphindwe iiyure ezingama-6 kunye nama-24 emva kovavanyo lokuqala. Jonga ezinye iimpawu ezinokuthi zibonise isifo sentliziyo.

I-Troponin luphawu oluphambili lwe-biochemical olusetyenziselwa ukuqinisekisa ukungafakwanga. Ukuxinana kwayo egazini kuqala ukunyuka emva kweeyure ezi-4 ukuya kwezi-8 emva kokubanjwa kwaye kubuyela koxinzelelo oluqhelekileyo emva kweentsuku ezili-10, ukubonakalisa kugqirha xa kuvavanyo. Ngaphandle kokuba luphawu oluphambili lwe-infarction, i-troponin ihlala ilinganiswa kunye nezinye izinto zokumakisha, ezinje nge-CK-MB kunye ne-myoglobin, egxile egazini iqala ukunyusa iyure enye emva kwesifo. Funda ngakumbi ngovavanyo lwe-myoglobin.

Uvavanyo lwe-troponin lunoku-odolwa ngenxa yezinye izizathu zomonakalo wentliziyo, njengakwiimeko ze-angina eziya zisiba mandundu ngokuhamba kwexesha, kodwa ezingazibonakalisi iimpawu zesifo.

Oko kuthethwa sisiphumo

Iziphumo zovavanyo lwe-troponin kubantu abasempilweni azibi, njengoko inani leeproteni ezikhutshelwe egazini liphantsi kakhulu, ngaphandle kokufunyanwa okanye ukungafunyanwa kwaphela. Ke, ukuba isiphumo asibi kwiiyure ezili-12 ukuya kwezi-18 emva kwentlungu yentliziyo, akunakulindeleka ukuba isifo sentliziyo senzeke, kwaye ezinye izizathu, ezinje ngegesi egqithileyo okanye iingxaki zokugaya, zinokwenzeka.

Xa iziphumo zilungile, oko kuthetha ukuba kukho ukulimala okanye utshintsho ekusebenzeni kwentliziyo. Amaxabiso aphezulu kakhulu ahlala engumqondiso wesifo sentliziyo, kodwa amaxabiso asezantsi anokubonisa ezinye iingxaki ezinje:

• Ukubetha kwentliziyo ngokukhawuleza okukhulu;
• Uxinzelelo lwegazi oluphezulu emiphungeni;
• Ukunyanzeliswa kwemiphunga;
• Ukungaphumeleli kwentliziyo;
• Ukudumba kwezihlunu zentliziyo;
• Unxunguphalo olubangelwa ziingozi zendlela;
• Isifo sezintso esinganyangekiyo.

Ngokwesiqhelo, amaxabiso eetroponin egazini atshintshwa malunga neentsuku ezili-10, kwaye anokuvavanywa ekuhambeni kwexesha ukuqinisekisa ukuba isilonda siphathwa ngokuchanekileyo.

Jonga oluphi uvavanyo onokulwenza ukuvavanya impilo yentliziyo yakho.