Libanda Cardiac glycoside

I-Cardiac glycosides ngamayeza okunyanga ukusilela kwentliziyo kunye nokubetha kwentliziyo okungaqhelekanga. Zezinye zeeklasi ezininzi zamachiza asetyenziselwa ukunyanga intliziyo kunye neemeko ezinxulumene noko. La machiza angunobangela oqhelekileyo wetyhefu.

Ukugqithisa kwe-cardiac glycoside kwenzeka xa umntu ethatha ngaphezu kwexabiso eliqhelekileyo okanye elicetyiswayo lonyango. Oku kunokuba ngengozi okanye ngenjongo.

I-Cardiac glycosides ifumaneka kwizityalo ezininzi, kubandakanya amagqabi esityalo se-digitalis (foxglove). Esi sityalo ngumthombo wokuqala eli yeza. Abantu abatya inani elikhulu lala magqabi banokuphuhlisa ukugqithisa.

Ityhefu yexesha elide (engapheliyo) inokwenzeka kubantu abathatha ii-glycosides zentliziyo yonke imihla. Oku kunokwenzeka xa umntu efumana iingxaki zezintso okanye ephelelwa ngamanzi emzimbeni (ngakumbi kwiinyanga zasehlotyeni ezishushu). Le ngxaki ihlala ivela kubantu abadala.

Eli nqaku lelolwazi kuphela. SUKUYISETYENZISE ukunyanga okanye ukulawula ukugqithisa ngokwenyani. Ukuba wena okanye umntu onokudlulela ngaphezulu, biza inombolo yakho yongxamiseko yendawo (enje nge-911), okanye iziko lakho lendawo yetyhefu linokufikelelwa ngokuthe ngqo ngokutsalela umnxeba kwinombolo yasimahla yetyhefu (1-800-222-1222) naphi na eUnited States.

I-Cardiac glycoside yikhemikhali enefuthe entliziyweni, esiswini, emathunjini, nakwinkqubo yemithambo-luvo. Sisithako esisebenzayo kumayeza ahlukeneyo entliziyo. Inokuba yityhefu ukuba ithathwe ngesixa esikhulu.

Iyeza digoxin iqulethe glycosides yentliziyo.

Ngaphandle kwesityalo se-foxglove, i-cardiac glycosides ikwenzeka ngokwendalo kwizityalo ezinje ngeLily-of-the-Valley kunye ne-oleander, phakathi kwezinye ezininzi.

Iimpawu zisenokungacaci, ngakumbi kubantu abadala.

Zinokwenzeka kwiindawo ezahlukeneyo zomzimba. Abo bane-asterisk ( *) ecaleni kwabo bahlala bevela kuphela kwii-overdoses ezingapheliyo.

AMEHLO, IINDlebe, iimpumlo, nomqala

• Umbono omfiliba
• IHalos ejikeleze izinto (mthubi, luhlaza, mhlophe) *

ULusu

• Ukusabela okungahambelaniyo komzimba, kubandakanya ne-Stevens-Johnson syndrome (irhashalala enzima kunye nobunzima bokuginya nokuphefumla)
• Imihlathi
• Irhashalala

ISisu kunye namathumbu

• Urhudo
• Ukuphelelwa ngumdla wokutya
• Isicaphucaphu nokugabha
• Intlungu yesisu

INTLIZIYO NEGAZI

• Ukubetha kwentliziyo okungaqhelekanga (okanye ukubetha kwentliziyo kancinci)
• Umothuko (uxinzelelo lwegazi olusezantsi kakhulu)
• Ubuthathaka

INKQUBO YENKONZO

• Ukudideka
• Uxinzelelo *
• Ukozela
• Ukufa isiqaqa
• Imibono hallucinations *
• Intloko ebuhlungu
• Ukuyeka okanye ubuthathaka

IMPILO YENGQONDO

• Ukungakhathali (ukungakhathali nantoni na)

Funa uncedo lwezonyango kwangoko. SUKUYENZE loo mntu ayilahle ngaphandle kokuba ulawula ityhefu okanye umniki-nkonzo akuxelela ukuba wenze njalo.

Ngaba olu lwazi lukulungele:

• Ubudala bomntu, ubunzima, kunye nemeko
• Igama lemveliso (kunye namandla, ukuba kuyaziwa)
• Ixesha laliginyiwe
• Isixa siginyiwe

Iziko lakho lokulawula ityhefu lingafikelelwa ngokuthe ngqo ngokutsalela umnxeba wenombolo yasimahla yasimahla (1800-222-1222) naphi na eUnited States. Le nombolo yesizwe iya kukuvumela ukuba uthethe neengcali kwiityhefu. Baza kukunika eminye imiyalelo.

Le yinkonzo yasimahla neyimfihlo. Onke amaziko olawulo lwetyhefu aseMelika asebenzisa le nombolo yesizwe. Kuya kufuneka ubize ukuba unemibuzo malunga netyhefu okanye ulawulo lwetyhefu. AKUFUNI ukuba ibe yingxakeko. Ungatsalela umnxeba nangasiphi na isizathu, iiyure ezingama-24 ngosuku, iintsuku ezisi-7 ngeveki.

Thatha isikhongozeli uhambe naso esibhedlele, ukuba kunokwenzeka.

Umboneleli uya kulinganisa kwaye abeke esweni iimpawu ezibalulekileyo zomntu, kubandakanya iqondo lobushushu, ukubetha kwentliziyo, izinga lokuphefumla, kunye noxinzelelo lwegazi.

Uvavanyo olunokwenziwa lunokubandakanya:

• Uvavanyo lwegazi kunye nomchamo
• I-x-ray yesifuba
• I-ECG (i-electrocardiogram, okanye ukulandelwa kwentliziyo)

Unyango lunokubandakanya:

• Amanzi afakwa ngaphakathi (anikezwe nge-vein)
• Iyeza lokunyanga iimpawu, kubandakanya i-antidote (iarhente yokuguqula)
• Amalahle avuselelweyo
• Izidambisi
• I-Pacemaker yentliziyo yokuphazamiseka kwentliziyo enesingqi esinzulu
• Ukuxhasa ukuphefumla, kubandakanya ityhubhu ngomlomo ukuya emiphungeni kwaye uqhagamshele kumatshini wokuphefumla (i-ventilator)
• I-renal dialysis (umatshini wezintso) kwiimeko ezinzima

Ukunciphisa ukusebenza kwentliziyo kunye nokuphazamiseka kwentliziyo yesingqi kunokubangela iziphumo ezibi. Ukufa kunokwenzeka, ngakumbi kubantwana abancinci nakwabadala. Abantu abadala ikakhulu banokubakho kwiingxaki zexesha elide (ezingapheliyo) zetyhefu yeglycoside yentliziyo.

Libanda, Digoxin; Libanda, Digitoxin; Libano Lanoxin; Libanda Purgoxin; Allocar libanda; Libanda Corramedan; Ukugqithisa kwe-Crystodigin

UAronons JK. Glycosides zentliziyo. Ku: Aronson JK, ed. Iziphumo ebezingalindelekanga zikaMeyler zeziyobisi. Ngomhla we-16. I-Waltham, MA: Elsevier; Ngo-2016: 117-157.

UCole JB. Iziyobisi zentliziyo. Ku: Iindonga RM, iHockberger RS, iGausche-Hill M, ii-eds. Unyango lukaRosen oluNgxamisekileyo: iikhonsepthi kunye nokuziqhelanisa neklinikhi. Umhla we-9. IPhiladelphia, PA: Elsevier; Ngo-2018: isahluko 147.