Ingxaki yeHemolytic

Ingxubakaxaka ye-hemolytic yenzeka xa inani elikhulu leeseli ezibomvu zegazi libhujiswa ngexesha elifutshane. Ukuphulukana neeseli ezibomvu zegazi kwenzeka ngokukhawuleza okukhulu kunokuba umzimba unokuvelisa iiseli ezibomvu zegazi.

Ngexesha lobunzima behemolytic, umzimba awunako ukwenza iiseli ezibomvu zegazi ezaneleyo ukubuyisela ezo zitshatyalalisiweyo. Oku kubangela i-anemia ebukhali kwaye ihlala ilukhuni.

Inxalenye yeeseli ezibomvu zegazi ezithwala ioksijini (ihemoglobin) ikhutshelwa egazini. Oku kungakhokelela ekonakaleni kwezintso.

Izizathu ze-hemolysis ziquka:

• Ukusilela kweeproteni ezithile ngaphakathi kweeseli ezibomvu zegazi
• Izifo ezizenzekelayo
• Izifo ezithile
• Iziphene kwiimolekyuli zehemoglobin ngaphakathi kweeseli ezibomvu zegazi
• Iziphene zeeproteni ezenza isakhelo sangaphakathi seeseli ezibomvu zegazi
• Iziphumo ebezingalindelekanga zamayeza athile
• Ukusabela kutofelo-gazi

Shayela umboneleli wakho wezempilo ukuba unayo:

• Iimpawu ze-anemia, kubandakanya ulusu olumhlophe okanye ukudinwa, ngakumbi ukuba ezi mpawu ziba mandundu
• Umchamo obomvu, obomvu-mdaka, okanye omdaka (umbala weti)

Unyango olungxamisekileyo lunokufuneka. Oku kunokubandakanya ukuhlala esibhedlele, ioksijini, utofelo-gazi, kunye nezinye iindlela zonyango.

Xa imeko yakho izinzile, umboneleli wakho uya kwenza uvavanyo lomzimba kwaye abuze malunga nembali yakho yonyango kunye neempawu. Uvavanyo lomzimba lunokubonisa ukudumba kwepeni (splenomegaly).

Uvavanyo olunokwenziwa lunokubandakanya:

• Iphaneli yekhemistri yegazi
• Gcwalisa ubalo lwegazi (CBC)
• Uvavanyo lweCombombs
• IHaptoglobin
• Lactate dehydrogenase

Unyango luxhomekeke kwisizathu se-hemolysis.

Hemolysis - etsolo

IGallagher PG. I-hemolytic anemias: inwebu ebomvu yegazi kunye neziphene kwimetabolism. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahl. 152.