Uvavanyo lwegazi lweGamma-glutamyl transferase (GGT)

Uvavanyo lwegazi lwe-gamma-glutamyl transferase (GGT) kwinqanaba le-enzyme GGT egazini.

Isampulu yegazi iyafuneka.

Umboneleli wezempilo angakuxelela ukuba uyeke ukuthatha amayeza anokuchaphazela uvavanyo.

Iziyobisi ezinokunyusa inqanaba le-GGT zibandakanya:

• Utywala
• IPhenytoin
• IPhenobarbital

Iziyobisi ezinokunciphisa inqanaba le-GGT zibandakanya:

• Iipilisi zokulawula inzala
• Clofibrate

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

I-GGT yi-enzyme efumaneka kwinqanaba eliphezulu esibindini, kwizintso, kwi-pancreas, entliziyweni nasengqondweni. Kufunyenwe nakwimali encinci kwezinye izicubu. I-enzyme yiprotein ebangela utshintsho oluthile lweekhemikhali emzimbeni.

Olu vavanyo lusetyenziselwa ukufumanisa izifo zesibindi okanye i-bile ducts. Kwakhona kwenziwa nezinye iimvavanyo (ezifana ne-ALT, i-AST, i-ALP, kunye neemvavanyo ze-bilirubin) ukuxelela umahluko phakathi kweengxaki zesibindi okanye i-bile kunye nesifo seethambo.

Inokwenziwa kwakhona ukukhusela, okanye ukubeka esweni, ukusetyenziswa kotywala.

Uluhlu oluqhelekileyo lwabadala luyi-5 ukuya kwi-40 U / L.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Inqanaba le-GGT elonyukayo linokubangelwa yiyo nayiphi na kwezi zinto zilandelayo:

• Ukusetyenziswa kotywala
• Seswekile
• Ukuhamba kwe-bile kwisibindi kuyavalwa (cholestasis)
• Ukumelwa yintliziyo
• Ukudumba kunye nokutsha kwesibindi (hepatitis)
• Ukungabikho kokuhamba kwegazi esibindini
• Ukufa kweethishu zesibindi
• Umhlaza wesibindi okanye ithumba
• Isifo semiphunga
• Isifo sepancreas
• Ukuqhekeka kwesibindi (i-cirrhosis)
• Ukusetyenziswa kweziyobisi eziyityhefu kwisibindi

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci kodwa inokubandakanya:

• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (ukuqokelela kwegazi phantsi kolusu)
• Ukopha kakhulu
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

I-Gamma-GT; I-GGTP; I-GGT; I-Gamma-glutamyl transpeptidase

IChernecky CC, iBerger BJ. I-Gamma-glutamyltranspeptidase (GGTP, gamma-glutamyltransferase) -igazi. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 559-560.

IPratt DS. I-chemistry yesibindi kunye novavanyo lomsebenzi. Ku: UFeldman M, uFriedman LS, uBrandt LJ, ii-eds. Sleisenger kunye neFordtran's Gastrointestinal and Liver Disease. Ngomhla we-10. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahluko 73.