Ixesha lecandelo le-thromboplastin (PTT)

Ixesha le-thromboplastin ekhethekileyo (i-PTT) luvavanyo lwegazi olujonga ukuba kuthabatha ixesha elingakanani ukuze igazi lijiye. Inokukunceda ukuxelela ukuba ngaba unengxaki yokopha okanye ukuba igazi lakho alinxibi ngokufanelekileyo.

Uvavanyo lwegazi olunxulumene noko lixesha leprothrombin (PT).

Isampulu yegazi iyafuneka. Ukuba uthatha nawaphi na amayeza okucoca igazi, uya kujongwa ngeempawu zokopha.

Umboneleli wakho wezempilo angakuxelela ukuba uyeke okwexeshana amayeza anokuchaphazela iziphumo zovavanyo. Qiniseka ukuba uxelela umboneleli wakho ngawo onke amayeza owathathayo. Xelela umboneleli wakho malunga naluphi na amayeza esintu owathathayo.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukutyumza kancinci. Oku kuya kuhamba kungekudala.

Ungaludinga olu vavanyo ukuba uneengxaki zokopha okanye igazi lakho aligqibi ngokufanelekileyo. Xa wopha, uthotho lwezenzo ezibandakanya iiproteni ezininzi ezahlukeneyo (izinto ezijiyisayo) zenzeka emzimbeni owanceda ihlwili legazi. Oku kubizwa ngokuba yi-coagulation cascade. Uvavanyo lwe-PTT lujonga ezinye zeeproteni okanye izinto ezichaphazelekayo kule nkqubo kwaye zilinganise amandla abo okunceda igazi.

Uvavanyo lungasetyenziselwa ukubeka esweni abaguli abathatha i-heparin, igazi elincinci.

Uvavanyo lwe-PTT luhlala lwenziwa nezinye iimvavanyo, ezinje ngovavanyo lweprothrombin.

Ngokubanzi, ukujiya kufuneka kwenzeke kwimizuzwana engama-25 ukuya kwengama-35. Ukuba umntu uthatha i-thinner yegazi, i-clotting ithatha ukuya kuma-2 ½ amaxesha ubude.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Iziphumo ezingaqhelekanga (ezinde kakhulu) ze-PTT zinokubangelwa:

• Ukuphazamiseka kwegazi, iqela leemeko apho kukho ingxaki kwinkqubo yegazi yomzimba
• Ukuphazamiseka apho iiproteni ezilawula ukujiya kwegazi ziye zisebenze ngakumbi (zisasazwe intravascular coagulation)
• Isifo sesibindi
• Unzima ukufunxa izondlo ekutyeni (malabsorption)
• Inqanaba eliphantsi levithamini K

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye, kwaye ukusuka kwelinye icala lomzimba ukuya kwelinye. Ukufumana isampulu yegazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukufa isiqaqa okanye ukuziva ungenantloko
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Ukugqobhoza okuninzi ukufumana imithambo
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Olu vavanyo luhlala lusenziwa kubantu abanokuba neengxaki zokopha. Umngcipheko wokopha uphezulu kancinci kunabantu abangenazo iingxaki zokopha.

APTT; PTT; Isebenze ixesha le-thromboplastin

• I-vein thrombosis enzulu - ukukhutshwa

IChernecky CC, iBerger BJ. Uvavanyo lwenxalenye ye-thromboplastin eyenziweyo yovavanyo-isifo. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 101-103.

I-Ortel TL. Unyango lwe-Antithrombotic. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 42.