Uvavanyo lwegazi lweProtheni C

Iprotein C yinto eqhelekileyo emzimbeni ethintela ukujiya kwegazi. Uvavanyo lwegazi lunokwenziwa ukubona ukuba ingakanani le proteni unayo egazini lakho.

Isampulu yegazi iyafuneka.

Amayeza athile anokutshintsha iziphumo zovavanyo lwegazi.

• Xelela umboneleli wakho wezempilo ngawo onke amayeza owasebenzisayo.
• Umboneleli wakho uya kukuxelela ukuba ngaba ufuna ukuyeka ukuthatha nawaphi na amayeza phambi kokuba wenze olu vavanyo. Oku kunokubandakanya abacoci begazi.
• Sukuyeka okanye ukutshintsha amayeza akho ungakhange uthethe nomboneleli wakho kuqala.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukutyumza kancinci. Oku kuya kuhamba kungekudala.

Unokulufuna olu vavanyo ukuba une-clot yegazi engachazwanga, okanye imbali yosapho yamahlwili egazi. Iprotein C inceda ukulawula ukujiya kwegazi. Ukunqongophala kwale protein okanye ingxaki nomsebenzi wale proteni kunokubangela ukuba amahlwili egazi enze kwimithambo.

Uvavanyo lukwasetyenziselwa ukujonga izihlobo zabantu abaziwayo ukuba banesiphene se-protein C. Kungenziwa kwakhona ukufumana isizathu sokuphazamiseka kwesisu okuphindaphindiweyo.

Amaxabiso aqhelekileyo angama-60% ukuya kuma-150% kuthintelo.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Ukusilela (ukusilela) kweprotein C kungakhokelela ekunqandeni okungaphezulu. La mahlule athambekele ekwenzeni imithambo, hayi imithambo.

Ukusilela kweeproteni C kunokudluliselwa kwiintsapho (ezizuzwe njengelifa). Inokuphinda ikhule nezinye iimeko, ezinje:

• Ukusetyenziswa kweChemotherapy
• Ukuphazamiseka apho iiproteni ezilawula ukujiya kwegazi ziye zisebenze ngakumbi (zisasazwe intravascular coagulation)
• Isifo sesibindi
• Ukusetyenziswa kwexesha elide kweyeza
• Ukusetyenziswa kweWarfarin (Coumadin)

Ingxaki enje ngehlwili legazi ngesiquphe emiphungeni inokunciphisa inqanaba le-protein C

Inqanaba le-Protein C lenyuka ngokuhamba kweminyaka, kodwa oku akubangeli naziphi na iingxaki zempilo.

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye, kwaye ukusuka kwelinye icala lomzimba ukuya kwelinye. Ukufumana isampulu yegazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

I-Autoprothrombin IIA

UAnderson JA, uHogg KE, uWeitz JI. Amazwe angenakuchaphazeleka. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ii-eds. I-Hematology: Imigaqo esisiseko kunye nokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 140.

IChernecky CC, iBerger BJ. Iprotein C (autoprothrombin IIA) - igazi. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 927-928.