Uvavanyo lwehomoni yokukhula

Uvavanyo lokukhula kwehomoni lilinganisa inani lokukhula kwehomoni egazini.

Idlala lengqula lenza ihomoni yokukhula, ebangela ukuba umntwana akhule. Le ndlala ibekwe emazantsi engqondo.

Isampulu yegazi iyafuneka.

Umboneleli wakho wezempilo unokukunika imiyalelo ekhethekileyo malunga nento onokuyitya okanye ongayityi ngaphambi kovavanyo.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

Le hormone inokukhangelwa ukuba ngaba ukukhula komntu akuqhelekanga okanye ukuba kurhanelwa enye imeko.

• Ukukhula kakhulu kwehomoni (GH) kunokubangela ukukhula okungaqhelekanga. Kubantu abadala, oku kubizwa ngokuba yi-acromegaly. Kubantwana, kubizwa ngokuba yi-gigantism.
• Ukukhula okuncinci kakhulu kwehomoni kunokubangela ukukhula kancinci okanye ngokuthe tyaba ekukhuleni kwabantwana. Kubantu abadala, ngamanye amaxesha kunokubangela utshintsho kumandla, ubunzima bemisipha, amanqanaba e-cholesterol, kunye nokomelela kwethambo.

Uvavanyo lwe-GH lunokusetyenziselwa ukubeka esweni impendulo kunyango lwe-acromegaly.

Uluhlu oluqhelekileyo lwenqanaba le-GH ngesiqhelo:

• Kubantu abadala abangamadoda - i-0.4 ukuya kwi-10 nanograms ngeemililitha (ng / ml), okanye i-18 ukuya kwi-44 i-picomoles ilitha nganye (pmol / L)
• Kubafazi ababudala-1 ukuya kwi-14 ng / mL, okanye i-44 ukuya kwi-616 pmol / L
• Kubantwana - i-10 ukuya kwi-50 ng / mL, okanye i-440 ukuya kwi-2200 pmol / L

I-GH ikhutshwa ngeempundu. Ubungakanani kunye nobude beempuphu buyahluka ngexesha losuku, ubudala, kunye nesini. Kungenxa yoko le nto imilinganiselo yeGH engacwangciswanga kunqabile ukuba ibe luncedo. Inqanaba eliphezulu kunokuba yinto eqhelekileyo ukuba igazi litsaliwe ngexesha lokubetha. Inqanaba elisezantsi linokuba yinto eqhelekileyo ukuba igazi lalitsaliwe ngapha kokuphela kokubetha. I-GH iluncedo kakhulu xa ilinganiswa njengenxalenye yovavanyo lokukhuthaza okanye lokucinezela.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Inqanaba eliphezulu leGH lingabonisa:

• I-GH eninzi kakhulu kubantu abadala, ebizwa ngokuba yi-acromegaly. (Uvavanyo olukhethekileyo lwenziwe ukuqinisekisa oku kufunyaniswa.)
• Ukukhula okungaqhelekanga ngenxa ye-GH egqithileyo ngexesha lobuntwana, ebizwa ngokuba yi-gigantism. (Uvavanyo olukhethekileyo lwenziwe ukuqinisekisa oku kufunyaniswa.)
• Ukuxhathisa kwe-GH.
• Ithumba lelungu lobufazi.

Inqanaba eliphantsi le-GH linokubonisa:

• Ukukhula kancinci okuphawulwe ebusaneni okanye ebuntwaneni, kubangelwa ngamanqanaba asezantsi e-GH. (Uvavanyo olukhethekileyo lwenziwe ukuqinisekisa oku kufunyaniswa.)
• I-Hypopituitarism (umsebenzi ophantsi wedlala yebhinqa).

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye, kwaye ukusuka kwelinye icala lomzimba ukuya kwelinye. Ukufumana isampulu yegazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi elakhiweyo phantsi kolusu)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Uvavanyo lweGH

• Ukukhula kovavanyo lokukhuthaza ihomoni-uthotho

UAli O. Hyperpituitarism, ubude obude, kunye ne-syndromes ezigqithileyo. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, ii-eds. Incwadi kaNelson yeNcwadi yePediatrics. Umhla wama-21. IPhiladelphia, PA: Elsevier; 2020: isahluko 576.

IChernecky CC, iBerger BJ. Ukukhula kwehomoni (somatotropin, GH) kunye nokukhula kwehomoni-ekhupha ihomoni (GHRH) -igazi. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. IPhiladelphia, PA: Elsevier Saunders; Ngo-2013: 599-600.

UCooke DW, iDivall SA, uRadovick S. Ukukhula kwesiqhelo kunye nokuchaphazeleka kwabantwana. Ku: UMelmed S, uAuchus RJ, uGoldfine AB, uKoenig RJ, uRosen CJ, ii-eds. Incwadi ebhaliweyo kaWilliam ye-Endocrinology. Umhla we-14. IPhiladelphia, PA: Elsevier; 2020: isahluko 25.