Uvavanyo lwegazi lweprolactin

Iprolactin yincindi yedlala ekhutshwe yidlala yebhinqa. Uvavanyo lweprolactin lilinganisa inani leprolactin egazini.

Isampulu yegazi iyafuneka.

Akukho lungiselelo lukhethekileyo luyimfuneko.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

Iprolactin yincindi yedlala ekhutshwe yidlala yebhinqa. I-pituitary yindlala encinci emazantsi engqondo. Ilawula umlinganiso womzimba wehomoni ezininzi.

Iprolactin ivuselela ukukhula kwamabele kunye nemveliso yobisi kubafazi. Akukho msebenzi uqhelekileyo uqhelekileyo weprolactin emadodeni.

Iprolactin ihlala ilinganiswa xa kujongwa amathumba esibeleko kunye nonobangela woku:

• Ukuveliswa kobisi lwebele olungahambelani nokuzala (galactorrhea)
• Ukuncipha kwesondo (i-libido) kumadoda nabasetyhini
• Iingxaki zokwakhiwa emadodeni
• Ayikwazi ukukhulelwa (ukungachumi)
• Ukungaqhelekanga okanye ukungabikho kwexesha (amenorrhea)

Amaxabiso aqhelekileyo eprolactin zezi:

• Amadoda: ngaphantsi kwama-20 ng / mL (425 µg / L)
• Abafazi abangakhulelweyo: ngaphantsi kwe-25 ng / mL (25 µg / L)
• Abafazi abakhulelweyo: 80 ukuya ku-400 ng / mL (80 ukuya ku-400 µg / L)

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nogqirha wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Abantu abanezi meko zilandelayo banokuba namanqanaba aphezulu eprolactin:

• Ukulimala kwesifuba okanye ukucaphuka
• Isifo sendawo yengqondo ebizwa ngokuba yihypothalamus
• Idlala lengqula alenzi ngokwaneleyo idlala lengqula (hypothyroidism)
• Isifo sezintso
• Ithumba lesisu elenza iprolactin (prolactinoma)
• Ezinye izilonda zepituitary kunye nezifo kwindawo yebhinqa
• Ukucocwa okungaqhelekanga kweemolekyuli zeprolactin (macroprolactin)

Amayeza athile anokuphakamisa inqanaba leprolactin, kubandakanya:

• Ukudakumba
• Iifowuni
• Estrogens
• Iibhloko ze-H2
• IMethyldopa
• Imetoclopramide
• Opiate amayeza
• Iiphenothiazines
• Hlaziya ngokutsha
• IRisperidone
• I-Verapamil

Iimveliso zentsangu nazo zinokunyusa inqanaba leprolactin.

Ukuba inqanaba lakho leprolactin liphezulu, uvavanyo lunokuphindaphindwa kusasa kwangoko emva kweeyure eziyi-8 ngokukhawuleza.

Oku kulandelayo kunokunyusa okwethutyana amanqanaba eprolactin:

• Uxinzelelo lweemvakalelo okanye lomzimba (ngamanye amaxesha)
• Ukutya okuneproteni ephezulu
• Ukukhuthaza ngamandla amabele
• Uvavanyo lwamva nje lwamabele
• Ukuzilolonga kutshanje

Ukutolikwa kovavanyo lwegazi oluphezulu ngokungaqhelekanga kunzima. Kwimeko ezininzi, umboneleli wakho uya kufuna ukukuthumela kwi-endocrinologist, ugqirha ogxile kwiingxaki zehomoni.

Akukho mngcipheko wokuthathwa kwegazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci kodwa inokubandakanya:

• Ukopha kakhulu
• Ukugqobhoza okuninzi ukufumana imithambo
• Ukufa isiqaqa okanye ukuziva ungenantloko
• I-Hematoma (igazi elakhiweyo phantsi kolusu)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

PRL; Uvavanyo lweGalactorrhea - iprolactin; Ukungachumi - uvavanyo lweprolactin; Amenorrhea - uvavanyo lweprolactin; Ukuvuza kwesifuba - uvavanyo lweprolactin; Prolactinoma - uvavanyo lweprolactin; Uvavanyo lwe-Pituitary tumor-prolactin

IChernecky CC, iBerger BJ. Iprolactin (iprolactin yomntu, i-HPRL) -iserum. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. IPhiladelphia, PA: Elsevier Saunders; Ngo-2013: 910-911.

UGuber HA, uFarag AF. Uvavanyo lomsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 24.

I-Kaiser U, Ho K. Indawo yokuma komzimba kunye novavanyo lokuqonda isifo. Ku: UMelmed S, uAuchus RJ, uGoldfine AB, uKoenig RJ, uRosen CJ, ii-eds. Incwadi ebhaliweyo kaWilliam ye-Endocrinology. Umhla we-14. IPhiladelphia, PA: Elsevier; 2020: isahl 8.