I-biopsy yamathambo

I-biopsy ye-nerve kukususa iqhekeza elincinci le-nerve yoviwo.

I-biopsy ye-nerve ihlala isenziwa kwi-nerve kwi-ankle, ingalo, okanye ecaleni kwembambo.

Umboneleli wokhathalelo lwempilo usebenzisa iyeza ukuphazamisa indawo ngaphambi kwenkqubo. Ugqirha usika utyando oluncinci kwaye asuse iqhekeza lemithambo-luvo. Ukunqunyulwa kuvaliwe emva koko kufakwe nebhandeji kuyo. Isampuli ye-nerve ithunyelwa elebhu, apho ihlolwa khona ngemicroscope.

Landela imiyalelo yomboneleli wakho malunga nendlela yokulungiselela inkqubo.

Xa iyeza elibindayo (i-anesthetic yendawo) itofiwe, uya kuziva ngathi uhlaba kwaye ulume kancinci. Indawo ye-biopsy inokuba buhlungu iintsuku ezimbalwa emva kovavanyo.

I-biopsy yamathambo inokwenziwa ukunceda ukufumanisa isifo:

• Ukonakala kwe-Axon (ukutshatyalaliswa kwenxalenye ye-axon yeseli ye-nerve)
• Ukonakala kweentsholongwane ezincinci
• I-Demyelination (ukutshatyalaliswa kweengxenye ze-myelin sheath egubungela i-nerve)
• Iimeko ezivuthayo zentsholongwane (i-neuropathies)

Imiqathango olunokuthi lwenziwe ngayo uvavanyo ibandakanya nayiphi na kwezi zinto zilandelayo:

• I-neuropathy yotywala (ukonakalisa imithambo-luvo kukusela utywala kakhulu)
• Ukungasebenzi kakuhle kwemithambo-luvo (umonakalo kwimbilini yegxalaba okhokelela ekuphulukaneni nentshukumo okanye imvakalelo egxalabeni)
• I-Brachial plexopathy (umonakalo kwi-plexus ye-brachial, indawo kwicala ngalinye lentamo apho iingcambu zentsholongwane ezivela kwintambo yomgogodla zahlula kwiimbilini zengalo nganye)
• Isifo seCharcot-Marie-Tooth (iqela elizuze ilifa leengxaki ezichaphazela imithambo-luvo engaphandle kwengqondo kunye nomqolo)
• Ukungasebenzi kakuhle kwemithambo-luvo (umonakalo kwi-neroneal nerve ekhokelela ekuphulukaneni nentshukumo okanye uvakalelo elunyaweni nasemlenzeni)
• Ukungasebenzi kakuhle kwamathambo (umonakalo kwi-nerve median ekhokelela ekuphulukaneni nentshukumo okanye uvakalelo ezandleni)
• I-mononeuritis multiplex (ingxaki ebandakanya ukonakala okungenani kwimimandla emibini)
• I-Necrotizing vasculitis (iqela leengxaki ezibandakanya ukuvuvukala kweendonga zemithambo yegazi)
• I-Neurosarcoidosis (ingxaki ye-sarcoidosis, apho ukudumba kwenzeka khona kwingqondo, umnqonqo, nakwezinye iindawo zenkqubo yeemvakalelo)
• Ukungasebenzi kakuhle kwemithambo-luvo (umonakalo kwi-radial nerve ekhokelela ekuphulukaneni nentshukumo okanye uvakalelo engalweni, esihlahleni okanye esandleni)
• Ukungasebenzi kakuhle kwethambo le-Tibial (ukonakala kwimbilini ye-tibial ekhokelela ekulahlekelweni kokuhamba okanye uvakalelo elunyaweni)

Iziphumo eziqhelekileyo zithetha ukuba imithambo-luvo ibonakala iqhelekile.

Iziphumo ezingaqhelekanga zinokubangelwa:

• I-Amyloidosis (i-sural nerve biopsy isetyenziswa rhoqo)
• Ukupheliswa kwenkqubo
• Ukudumba luvo
• Iqhenqa
• Ukuphulukana nezicubu ze-axon
• I-metabolic neuropathies (ukuphazamiseka kwemithambo-luvo eyenzeka ngezifo eziphazamisa iinkqubo zeekhemikhali emzimbeni)
• Ukutsala i-vasculitis
• I-Sarcoidosis

Umngcipheko wale nkqubo unokubandakanya:

• Ukuphendula ngokuthe ngqo kwi-anesthetic yendawo
• Ingxaki emva kwenkqubo
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)
• Umonakalo osisigxina (ongaqhelekanga; uncitshiswe ngokukhetha indawo ngononophelo)

I-biopsy yamathambo iyangena kwaye iluncedo kuphela kwiimeko ezithile. Thetha nomboneleli wakho malunga nokukhetha kwakho.

Biopsy - luvo

• I-biopsy yamathambo

IChernecky CC, iBerger BJ. I-biopsy yamathambo-isifo. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 814-815.

UMidha R, uElmadhoun TMI. Uvavanyo lwe-peripheral luvo, uvavanyo, kunye ne-biopsy. Ku: Winn HR, ed. Ugqirha we-Youmans kunye no-Winn Neurological. Umhla wesi-7. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 245.