Unyango lwe-Thrombolytic

Unyango lwe-Thrombolytic kukusetyenziswa kweziyobisi ukwaphula okanye ukunyibilikisa amahlwili egazi, angoyena nobangela uphambili wokuhlaselwa sisifo sentliziyo kunye nokubetha.

Amayeza e-Thrombolytic avunyiwe kunyango lwe-stroke kunye ne-heart attack. Esona siyobisi sisetyenziswa rhoqo kunyango lwe-thrombolytic sisicubu seplasminogen activator (tPA), kodwa ezinye iziyobisi zinokwenza into efanayo.

Ngokufanelekileyo, kuya kufuneka ufumane amayeza e-thrombolytic kwimizuzu yokuqala engama-30 emva kokufika esibhedlele ukuze ufumane unyango.

UKUHLASELWA YINTLIZIYO

Ihlwili legazi linokuthintela imithambo entliziyweni. Oku kunokubangela ukuba uhlaselwe sisifo sentliziyo, xa inxenye yemisipha yentliziyo isifa ngenxa yokunqongophala kweoksijini ehanjiswa ligazi.

I-Thrombolytics isebenza ngokuphelisa i-clot enkulu ngokukhawuleza. Oku kunceda ukuqala kwakhona ukuhamba kwegazi kuye entliziyweni kwaye kunceda ukuthintela ukonakala kwizihlunu zentliziyo. I-Thrombolytics inokumisa ukuhlaselwa yintliziyo enokuthi ibe nkulu okanye ibe yingozi. Iziphumo zingcono ukuba ufumana ichiza le-thrombolytic kwisithuba seeyure ezili-12 emva kokuhlaselwa kwentliziyo. Kodwa ngokukhawuleza unyango luqala, bhetele iziphumo.

Iyeza libuyisela ukuphuma kwegazi entliziyweni yabantu abaninzi. Nangona kunjalo, ukuhamba kwegazi akunakuba yinto eqhelekileyo kwaye kusenokubakho isixa esincinci semisipha esonakeleyo. Unyango olungaphezulu, olufana ne-catheterization yentliziyo kunye ne-angioplasty kunye ne-stenting, kunokufuneka.

Umboneleli wakho wezempilo uya kuseka izigqibo malunga nokuba akunike na iyeza le-thrombolytic lokuhlaselwa sisifo sentliziyo kwizinto ezininzi. Ezi zinto zibandakanya imbali yakho yesifuba kunye neziphumo zovavanyo lwe-ECG.

Eminye imiba esetyenziselwa ukumisela ukuba ungumgqatswa olungileyo we-thrombolytics ibandakanya:

• Ubudala (abantu abadala basemngciphekweni wokwanda kweengxaki)
• Ukwabelana ngesondo
• Imbali yezonyango (kubandakanya nembali yokuhlaselwa sisifo sentliziyo, isifo seswekile, uxinzelelo lwegazi okanye ukunyuka kwentliziyo)

Ngokubanzi, i-thrombolytics ayinakunikwa ukuba unayo:

• Ukulimala kwentloko kwangoku
• Iingxaki zokopha
• Izilonda zokopha
• Ukukhulelwa
• Utyando lwamva nje
• Thatha amayeza okucoca igazi njengeCoumadin
• Umonzakalo
• Ukungalawulwa (okunzima) uxinzelelo lwegazi oluphezulu

IZIBHAMU

Uninzi lweemivumbo zibangelwa xa amahlwili egazi esiya kwisitya segazi kwingqondo kwaye uvimba ukuhamba kwegazi kuloo ndawo. Kwimivumbo enjalo (imivumbo ye-ischemic), i-thrombolytics inokusetyenziselwa ukunceda ukunyibilikisa ihlwili ngokukhawuleza. Ukunika i-thrombolytics kungaphelanga neeyure ezi-3 zeempawu zokuqala zestroke kunokunceda ukunciphisa umda womonakalo kunye nokukhubazeka.

Isigqibo sokunika iyeza lisekwe:

• Iskena se-CT sokuqinisekisa ukuba akubikho gazi
• Uvavanyo lomzimba olubonisa ukubetha okubonakalayo
• Imbali yakho yonyango

Njengasekuhlaselweni yintliziyo, ichiza elinyibilikayo alifane linikezwe ukuba unayo enye yeengxaki zonyango ezidweliswe apha ngasentla.

I-Thrombolytics ayinikwa umntu onesifo esibuhlungu esibandakanya ukopha kwingqondo. Bangasenza mandundu isibetho ngokubangela ukopha okungaphezulu.

IINGOZI

Ukopha yeyona nto ixhaphakileyo. Ingasongela ubomi.

Ukopha kancinci kwiintsini okanye empumlweni kunokwenzeka malunga neepesenti ezingama-25 zabantu abafumana iyeza. Ukopha ebuchotsheni kwenzeka malunga ne-1% yexesha. Lo mngcipheko uyafana kokubini ukubetha kunye nokuhlaselwa sisifo sentliziyo.

Ukuba i-thrombolytics ivakalelwa ngathi iyingozi kakhulu, ezinye iindlela zonyango ezinokubangela ukubetha okanye ukubetha kwentliziyo zibandakanya:

• Ukususwa kwehlwili (thrombectomy)
• Inkqubo yokuvula imithambo yegazi emxinwa okanye evaliweyo ehambisa igazi entliziyweni okanye kwingqondo

UQHAGAMSHELWANO NOMBONELELI OKHULULEKILEYO WEZEMPILO OKANYE FONELA 911

Ukuhlaselwa sisifo sentliziyo kunye nemivumbo zizinto ezingxamisekileyo zonyango. Unyango kwangoko kunye ne-thrombolytics luqala, ngcono ithuba lesiphumo esihle.

I-activator yethisue yeethishu; TPA; Indawo yokubhala Phinda ubeke; Tenecteplase; Isebenze arhente thrombolytic; Iiarhente zokunyibilikisa indawo Unyango lotshintsho; Stroke - thrombolytic; Isifo sentliziyo - thrombolytic; Embolism Acute - thrombolytic; Thrombosis - thrombolytic; ILanoteplase; IStaphylokinase; IStreptokinase (SK); Urokinase; Stroke - unyango thrombolytic; Isifo sentliziyo - unyango thrombolytic; Stroke - thrombolysis; Isifo sentliziyo - thrombolysis; Isifo sephepha engabalulekanga - thrombolysis

• Ukubetha
• ITrombus
• Thumela ii-ECG ze-infyoction ye-myocardial infarction

I-Bohula EA, iMorrow DA. I-ST-election infyoction ye-myocardial infarction: ulawulo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ii-eds. Isifo sentliziyo seBraunwald: Incwadi yesifundo seMpilo yeNtliziyo. Ngomhla we-11. IPhiladelphia, PA: Elsevier; I-2019: isahluko 59.

ICrocco TJ, uMnyangi WJ. Ukubetha. Ku: Iindonga RM, iHockberger RS, iGausche-Hill M, ii-eds. Unyango lukaRosen oluNgxamisekileyo: iikhonsepthi kunye nokuziqhelanisa neklinikhi. Umhla we-9. IPhiladelphia, PA: Elsevier; I-2018: isahluko 91.

UJaffer IH, Weitz JI. Iziyobisi Antithrombotic. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ii-eds. I-Hematology: Imigaqo esisiseko kunye nokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 149.

U-OGara PT, uKushner FG, uAscheim DD, et al. Isikhokelo se-ACCF / AHA sika-2013 kulawulo lwe-ST-elevation myocardial infarction: ingxelo yeAmerican College of Cardiology Foundation / American Heart Association Task Force kwiZikhokelo zokuSebenza. Ukujikeleza. Ngo-2013; 127 (4): 529-555. IINKCUKACHA: 23247303 pubmed.ncbi.nlm.nih.gov/23247303/.