Uvavanyo lweTroponin

Uvavanyo lwe-troponin lulinganisa amanqanaba e-troponin T okanye ye-troponin I yeeproteni egazini. Ezi proteni zikhutshwa xa izihlunu zentliziyo zonakalisiwe, ezinje ngokuhlaselwa sisifo sentliziyo. Okukhona kukho umonakalo omkhulu entliziyweni, kokukhona isixa setroponin T nam siya kuba segazini.

Isampulu yegazi iyafuneka.

Akukho manyathelo akhethekileyo ayimfuneko ukulungiselela, uninzi lwamaxesha.

Unokuziva iintlungu okanye ulwamvila xa kufakwa inaliti. Unokuziva ubethwa sisiza emva kokuba kuthathwe igazi.

Esona sizathu siqhelekileyo sokwenza olu vavanyo kukubona ukuba isifo sentliziyo senzekile. Umboneleli wakho wezempilo uya kuyalela olu vavanyo ukuba unentlungu esifubeni kunye nezinye iimpawu zesifo sentliziyo. Uvavanyo luhlala luphindaphindwe kabini ngaphezulu kweeyure ezi-6 ukuya kwezi-24 ezizayo.

Umboneleli wakho unokuyalela olu vavanyo ukuba une-angina eya isiba mandundu, kodwa azikho ezinye iimpawu zesifo sentliziyo. (UAngina iintlungu zesifuba ekucingelwa ukuba zivela kwinxalenye yentliziyo yakho engafumani gazi laneleyo.)

Uvavanyo lwe-troponin lunokwenziwa ukunceda ukufumanisa kunye nokuvavanya ezinye izizathu zokulimala kwentliziyo.

Uvavanyo lunokwenziwa kunye nolunye uvavanyo lweempawu zentliziyo, ezinje nge-CPK isoenzymes okanye i-myoglobin.

Amanqanaba e-Cardiac troponin aqhelekileyo asezantsi kangangokuba awanakufunyanwa kuvavanyo lwegazi.

Ukuba namanqanaba aqhelekileyo etroponin kwiiyure ezili-12 emva kokuba iintlungu zesifuba sele ziqalisile kuthetha ukuba isifo sentliziyo asinakulindeleka.

Uluhlu lwamaxabiso aqhelekileyo lungahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo (umzekelo, "uvavanyo oluphezulu lwetroponin test") okanye ukuvavanya iisampulu ezahlukeneyo. Kwakhona, ezinye iilebhu zinendawo ezahlukileyo zokusika "eziqhelekileyo" kunye "ne-infyoction ye-myocardial infarction." Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Nokuba ukonyuka okuncinci kwinqanaba le-troponin kuya kuhlala kuthetha ukuba kukho umonakalo othile entliziyweni. Amanqanaba aphezulu kakhulu etroponin luphawu lokuba isifo sentliziyo senzekile.

Uninzi lwezigulana ezihlaselwe sisifo sentliziyo zonyuse amanqanaba etroponin kwisithuba seeyure ezingama-6. Emva kweeyure ezili-12, phantse wonke umntu oye wahlaselwa sisifo sentliziyo uya kube enyuse amanqanaba.

Amanqanaba eTroponin anokuhlala ephezulu kwiiveki ezi-1 ukuya kwezi-2 emva kokuhlaselwa sisifo sentliziyo.

Ukunyusa amanqanaba etroponin kunokubangelwa:

• Ukubetha kwentliziyo ngokungaqhelekanga
• Uxinzelelo lwegazi oluphezulu kwimithambo yemiphunga (uxinzelelo lwegazi)
• Ukuvaleka kwemithambo yamaphaphu ngegazi, amanqatha, okanye iiseli zethumba (pulmonary embolus)
• Ukusilela kwentliziyo
• Umthambo weCoronary spasm
• Ukudumba kwentliziyo yemisipha ngesiqhelo ngenxa yentsholongwane (myocarditis)
• Ukuzivocavoca ixesha elide (umzekelo, ngenxa yeemarathoni okanye iitraton)
• Umonzakalo owenzakalisa intliziyo, njengengozi yemoto
• Ukwenza buthathaka kwemisipha yentliziyo (cardiomyopathy)
• Isifo sezintso sexesha elide

Ukunyusa amanqanaba etroponin kunokubangelwa ziinkqubo ezithile zonyango ezinje:

• I-angioplasty yentliziyo / ukuqaqamba
• Intsingiselo yentliziyo okanye ukubuyisa ukuphefumla ngombane (ukothuka okunenjongo kwentliziyo ngabasebenzi bezonyango ukulungisa isingqisho sentliziyo esingaqhelekanga)
• Utyando lwentliziyo oluvulekileyo
• Radiofrequency ablation yentliziyo

ITroponinI; TNI; ITroponinT; TnT; I-troponin ekhethekileyo ye-Cardiac; I-troponin ekhethekileyo ye-Cardiac; cTnl; cTnT

I-Bohula EA, iMorrow DA. I-ST-Ukuphakama kwe-myocardial infarction: ulawulo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ii-eds. Isifo sentliziyo seBraunwald: Incwadi yesifundo seMpilo yeNtliziyo. Ngomhla we-11. IPhiladelphia, PA: Elsevier; 2018: isahluko 59.

Bonaca, MP, Sabatine MS. Indlela kwisigulana esineentlungu esifubeni. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ii-eds. Isifo sentliziyo seBraunwald: Incwadi yesifundo seMpilo yeNtliziyo. Ngomhla we-11. IPhiladelphia, PA: Elsevier; I-2019: isahluko 56.

U-Levine GN, ii-Bates ER, i-Blankenship JC, et al. Ngo-2015 i-ACC / AHA / i-SCAI kugxilwe ekuhlaziyweni kongenelelo ngoncedo lwe-coronary kwizigulana ezine-ST-Elevation myocardial infarction: uhlaziyo lwe-2011 ACCF / AHA / SCAI isikhokelo songenelelo ngoncedo lwe-coronary kunye ne-2013 ACCF / AHA isikhokelo kulawulo lwe-ST- Ukuphakama kwe-infyoction ye-myocardial infarction: ingxelo ye-American College of Cardiology / American Heart Association Task Force kwizikhokelo zeklinikhi kunye noMbutho we-Cardiovascular Angiography kunye nongenelelo. Ukujikeleza. Ngo-2016; 133 (11): 1135-1147. IINKCUKACHA: 26490017 www.ncbi.nlm.nih.gov/pubmed/26490017.

I-Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, White HD; IQela eliLawulayo egameni leJoint European Society of Cardiology (ESC) / American College of Cardiology (ACC) / American Heart Association (AHA) / World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction. Inkcazo yesine kwi-Myocardial Infarction (2018). Ukujikeleza. 2018; 138 (20): e618-e651 PMID: 30571511 www.ncbi.nlm.nih.gov/pubmed/30571511.