IHodgkin lymphoma ebantwaneni

IHodgkin lymphoma ngumhlaza wamathambo e-lymph. Izicubu ze-lymph zifumaneka kwii-lymph nodes, spleen, tonsils, isibindi, umongo wethambo kunye namanye amalungu omzimba. Amajoni omzimba asikhusela kwizifo kunye nosulelo.

Eli nqaku limalunga neklasikhi iHodgkin lymphoma ebantwaneni, olona hlobo luqhelekileyo.

Kubantwana, iHodgkin lymphoma kunokwenzeka ukuba yenzeke phakathi kweminyaka eli-15 ukuya kweli-19. Unobangela wolu hlobo lomhlaza awaziwa. Kodwa, izinto ezithile zinokudlala indima kwiHodgkin lymphoma ebantwaneni. Ezi zinto zibandakanya:

• Intsholongwane ka-Epstein-Barr, intsholongwane ebangela i-mononucleosis
• Ezinye izifo apho amajoni omzimba engasebenzi kakuhle
• Imbali yosapho yeHodgkin lymphoma

Izifo eziqhelekileyo zosulelo lwabantwana nazo zinokunyusa umngcipheko.

Iimpawu zeHodgkin lymphoma zibandakanya:

• Ukuvuvukala okungenasiphelo kwe-lymph nodes entanyeni, emakhwapheni, okanye kwi-groin (izilonda ezivuvukileyo)
• Umkhuhlane ongachazwanga
• Ukuphulukana nobunzima obungachazwanga
• Ukubila ebusuku
• Ukudinwa
• Ukuphelelwa ngumdla wokutya
• Ukurhawuzelela umzimba wonke

Umboneleli wezempilo uya kuthatha imbali yezonyango yomntwana wakho. Umboneleli uya kwenza uvavanyo lomzimba ukukhangela ukuba ii-lymph node zidumbile.

Umboneleli unokwenza ezi mvavanyo zelebhu xa isifo seHodgkin sikrokrelwa:

• Uvavanyo lwe-chemistry yegazi-kubandakanya amanqanaba eprotini, uvavanyo lwesibindi, uvavanyo lwezintso, kunye nenqanaba leuric acid
• I-ESR ("Inqanaba leSed")
• Gcwalisa ubalo lwegazi (CBC)
• I-x-ray yesifuba, ehlala ibonisa iimpawu zobunzima kwindawo phakathi kwemiphunga

I-lymph node biopsy iqinisekisa ukuxilongwa kweHodgkin lymphoma.

Ukuba i-biopsy ibonisa ukuba umntwana wakho une-lymphoma, kuya kwenziwa iimvavanyo ezininzi ukufumanisa ukuba umhlaza usasazeke kangakanani. Oku kubizwa ngokuba yistage. Ukubeka esiteji kunceda ukukhokelela kunyango lwexesha elizayo kunye nokulandela.

• Ukuvavanywa kwe-CT kwentamo, isifuba, isisu kunye nesinqe
• Umongo wethambo
• Ukuskena iPET

I-Immunophenotyping luvavanyo lwaselebhu olusetyenziselwa ukufumanisa iiseli, ngokusekwe kwiindidi zeantigen okanye ezimakishayo phezu kweseli. Olu vavanyo lusetyenziselwa ukufumanisa uhlobo oluthile lwe-lymphoma ngokuthelekisa iiseli zomhlaza kwiiseli eziqhelekileyo zomzimba.

Unokukhetha ukufuna ukhathalelo kwiziko lomhlaza labantwana.

Unyango luya kuxhomekeka kwiqela elinomngcipheko awele kulo umntwana wakho. Eminye imiba eza kuqwalaselwa ibandakanya:

• Iminyaka yomntwana wakho
• Ukwabelana ngesondo
• Iziphumo zonyango

I-lymphoma yomntwana wakho iya kudityaniswa njengomngcipheko ophantsi, umngcipheko ophakathi, okanye umngcipheko ophezulu ngokusekwe:

• Uhlobo lweHodgkin lymphoma (kukho iindlela ezahlukeneyo zeHodgkin lymphoma)
• Inqanaba (apho isifo sisasazeke khona)
• Nokuba lithumba eliphambili likhulu kwaye lihlelwe "sisifo esimbaxa"
• Ukuba lo ngumhlaza wokuqala okanye ubuyile (uphindaphindiwe)
• Ubukho befiva, ukwehla kobunzima, kunye nokubila ebusuku

I-Chemotherapy ihlala inyango lokuqala.

• Umntwana wakho unokufuna ukuhlala esibhedlele ekuqaleni. Kodwa amayeza e-chemotherapy ahlala enikwa ekliniki, kwaye umntwana wakho uya kuhlala ekhaya.
• I-Chemotherapy inikwa imithambo (IV) kwaye ngamanye amaxesha ngomlomo.

Umntwana wakho unokufumana unyango ngemitha usebenzisa ii-x-reyi ezinamandla aphezulu kwiindawo ezichaphazelekileyo ngumhlaza.

Olunye unyango lunokubandakanya:

• Unyango ekujoliswe kulo olusebenzisa iziyobisi okanye izilwa-buhlungu ukubulala iiseli zomhlaza
• Unyango oluphezulu lwe-chemotherapy lunokulandelwa ukufakelwa kweeseli (usebenzisa iiseli zomntwana wakho)
• Uqhaqho alusetyenziswa rhoqo ukususa olu hlobo lomhlaza, kodwa lunokufuneka kwiimeko ezinqabileyo

Ukuba nomntwana onomhlaza yenye yezona zinto zinzima oya kujongana nazo njengomzali. Ukuchaza ukuba kuthetha ukuthini ukuba nomhlaza emntwaneni wakho akuyi kuba lula. Kuya kufuneka ufunde ukuba ungalufumana njani uncedo kunye nenkxaso ukuze ukwazi ukumelana ngokulula.

Ukuba nomntwana onomhlaza kunokuba noxinzelelo. Ukujoyina iqela lenkxaso apho abanye abazali okanye iintsapho zabelana ngamava aqhelekileyo kunokunceda ukunciphisa uxinzelelo lwakho.

• Umhlaza wegazi kunye noMbutho weLymphoma- www.lls.org
• Umbutho weSizwe woMhlaza waBantwana-www.thenccs.org/how-we-help/

IHodgkin lymphoma iyanyangeka kwiimeko ezininzi. Nokuba olu hlobo lomhlaza luyabuya, amathuba onyango alungile.

Umntwana wakho kuya kufuneka enze iimviwo rhoqo kunye neemvavanyo zokucinga ngeminyaka emva konyango. Oku kuya kunceda umboneleli akhangele iimpawu zokubuyela komhlaza kunye naziphi na iziphumo zonyango lwexesha elide.

Unyango lweHodgkin lymphoma lunokuba neengxaki. Iziphumo ebezingalindelekanga zonyango lwe-chemotherapy okanye unyango ngemitha zinokubonakala iinyanga okanye iminyaka emva konyango. Oku kubizwa ngokuba "kukugqibela kweziphumo." Kubalulekile ukuthetha ngeziphumo zonyango kunye neqela lakho lokhathalelo lwempilo. Yintoni onokuyilindela malunga neziphumo ezifike kade kuxhomekeke kunyango oluthile olufunyanwa ngumntwana wakho. Inkxalabo yeziphumo ezifike emva kwexesha kufuneka ilungelelaniswe yimfuno yokunyanga nokunyanga umhlaza.

Qhubeka nokulandela ugqirha womntwana wakho ukuba abeke esweni kwaye ancede ukuthintela ezi ngxaki.

Nxibelelana nomboneleli wakho ukuba umntwana wakho une-lymph node ezidumbileyo ezinomkhuhlane ohlala ixesha elide okanye unezinye iimpawu zeHodgkin lymphoma. Tsalela umnikezeli womntwana wakho ukuba umntwana wakho uneHodgkin lymphoma kwaye uneziphumo ebezingalindelekanga kunyango.

Lymphoma - Hodgkin - abantwana; Isifo seHodgkin - abantwana; Umhlaza - iHodgkin lymphoma - abantwana; Ubuntwana Hodgkin lymphoma

Umbutho waseMelika we-Clinical Oncology (ASCO) iwebhusayithi. I-Lymphoma - Hodgkin - ubuntwana. www.cancer.net/cancer-types/lymphoma-hodgkin-childhood. Ukuhlaziywa kweDisemba 2018. Ifikeleleke ngo-Okthobha 7, 2020.

IHochberg J, iGoldman SC, iCairo MS. KwiLymphoma. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, ii-eds. Incwadi kaNelson yeNcwadi yePediatrics. Umhla wama-21. IPhiladelphia, PA: Elsevier; 2020: isahluko 523.

Kwiwebhusayithi yeZiko loMhlaza weSizwe. Unyango lweHodgkin lymphoma yobuntwana (PDQ) -uhlobo lobungcali kwezempilo. www.cancer.gov/types/lymphoma/hp/child-hodgkin- unyango-pdq. Ukuhlaziywa ngoFebruwari 3, 2021. Kufumaneka ngoFebruwari 23, 2021.