Indawo yokuthambisa

I-Cologuard luvavanyo lokuvavanya umhlaza wekolon kunye nomhlaza wamanqwanqwa.

Ikholoni ikhupha iiseli kwindawo yayo yonke imihla. Ezi seli zidlula ngestool ngokusebenzisa ikholoni. Iiseli zomhlaza zinokutshintsha kwe-DNA kwiijeni ezithile. I-Cologuard ifumanisa iDNA eguqulweyo. Ubukho beeseli ezingaqhelekanga okanye igazi esitulweni kunokubonisa umhlaza okanye izilonda zesikhumba.

Ikhithi yokuvavanywa kweCologuard yomhlaza wekolon kunye nomhlaza wesibeleko kufuneka iyalelwe ngumboneleli wakho wezempilo. Iya kuthunyelwa ngeposi kwidilesi yakho. Uqokelela isampulu ekhaya kwaye uyithumele kwilebhu yovavanyo.

Ikhithi yokuvavanya iCologuard iya kuba nesikhongozeli sesampulu, ityhubhu, igcina ulwelo, iilebhile kunye nemiyalelo malunga nokuqokelela isampulu. Xa ukulungele ukuba nentshukumo yamathumbu, sebenzisa ikhithi yokuvavanya iCologuard ukuqokelela isampulu yakho yendle.

Funda imiyalelo eza kunye nekiti yovavanyo ngononophelo. Linda ude ube ukulungele ukuba nokuhamba kwamathumbu. Qokelela isampulu kuphela xa kunokwenzeka ukuba uyithumele ngaphakathi kweeyure ezingama-24. Isampulu kufuneka ifike elebhu kwiiyure ezingama-72 (iintsuku ezi-3).

Sukuqokelela isampulu ukuba:

• Unorhudo.
• Usexesheni.
• Ukopha emacaleni ngenxa yeemvumba.

Landela la manyathelo ukuqokelela isampulu:

• Funda yonke imiyalelo eza nekiti.
• Sebenzisa izibiyeli ezinikezwe ikiti yovavanyo ukulungisa isampulu yesikhongozeli kwisihlalo sakho sangasese.
• Sebenzisa indlu yangasese njengesiqhelo xa uhambisa amathumbu.
• Zama ukungavumeli umchamo ungene kwisitya sesampulu.
• Musa ukubeka iphepha langasese kwisikhongozeli sesampulu.
• Nje ukuba ukuhamba kwamathumbu kugqityiwe, susa isampulu yesikhongozeli kubakaki kwaye ugcine endaweni ethe tyaba.
• Landela imiyalelo yokuqokelela isampulu encinci kwityhubhu ebonelelwe ngekhithi yokuvavanya.
• Thela ulwelo olugcinayo kwisitya sesampulu kwaye uvale isiciko ngokuqinileyo.
• Bhala iityhubhu kunye nesitya sesampulu ngokwemiyalelo, kwaye uzibeke ebhokisini.
• Gcina ibhokisi kubushushu begumbi, kude nelanga kunye nobushushu.
• Thumela ibhokisi ngaphakathi kweeyure ezingama-24 kwilebhu usebenzisa ileyibhile enikiweyo.

Iziphumo zovavanyo ziya kuthunyelwa kumboneleli wakho kwiiveki ezimbini.

Uvavanyo lweCologuard alufuni lungiselelo. Awudingi ukutshintsha indlela otya ngayo okanye amayeza ngaphambi kovavanyo.

Uvavanyo lufuna ukuba ube nokuhamba kwamathumbu okuqhelekileyo. Ayizukuva umohluko ekuhambeni kwakho rhoqo. Ungayiqokelela isampuli ekhayeni lakho ngasese.

Uvavanyo lwenziwe kwiscreen somhlaza kunye nomhlaza we-rectal kunye nokukhula okungaqhelekanga (iipolyps) kwikholoni okanye kwi-rectum.

Umboneleli wakho unokucebisa ukuvavanywa kweCologuard kanye kwiminyaka emithathu emva kweminyaka engama-50. Uvavanyo luyacetyiswa ukuba uphakathi kweminyaka engama-50 ukuya kwengama-75 kwaye unomngcipheko ophakathi womhlaza wekolon. Oku kuthetha ukuba awunayo:

• Imbali yobuqu ye-colon polyps kunye nomhlaza wekolon
• Imbali yosapho yomhlaza wekolon
• Isifo samathumbu esivuthayo (isifo seCrohn, isifo sezilonda)

Iziphumo eziqhelekileyo (iziphumo ezibi) ziya kubonisa ukuba:

• Uvavanyo aluzange lubhaqe iiseli zegazi okanye lutshintshe iDNA kwisitulo sakho.
• Awudingi ukuvavanywa ngakumbi komhlaza wekolon ukuba unomngcipheko ophakathi womhlaza wekolon okanye umhlaza.

Iziphumo ezingaqhelekanga (iziphumo ezincumisayo) zibonisa ukuba uvavanyo lufumene iiseli zangaphambi komhlaza okanye iiseli zomhlaza. Nangona kunjalo, uvavanyo lweCologuard aluchongi umhlaza. Uya kudinga olunye uvavanyo ukuze ufumane isifo somhlaza. Umboneleli wakho uya kuphakamisa ikholonoscopy.

Akukho bungozi buthatha inxaxheba ekuthatheni isampulu kuvavanyo lweCologuard.

Uvavanyo lokuvavanywa lubeka umngcipheko omncinci woku:

• Iziphumo zobuxoki (iziphumo zakho zovavanyo aziqhelekanga, kodwa awunawo umhlaza wekolon okanye iipolyps ezinobungozi)
• Izinto ezingezizo (uvavanyo lwakho luqhelekile nokuba unomdlavuza wekolon)

Akukacaci nokuba ukusetyenziswa kweCologuard kuya kukhokelela kwiziphumo ezingcono xa kuthelekiswa nezinye iindlela ezisetyenziselwa ukukrola umhlaza wekolon kunye nomhlaza wamanqwanqwa.

Cologuard; Ukuvavanywa komhlaza wamathumbu - iCologuard; Uvavanyo lweStool DNA - iCologuard; Uvavanyo lwestool seFIT-DNA; Uvavanyo lweColon precancer-Cologuard

• Amathumbu amakhulu (ikholoni)

ICotter TG, iBurger KN, inyanzelekile kum, et al. Ukulandelwa kwexesha elide kwabaguli abane-stool ye-stool ye-stool ye-multitgetget positive emva kovavanyo olubi lwe-colonoscopy: isifundo seqela se-LONG-HAUL. Umhlaza we-Epidemiol Biomarkers ezidlulileyo. Ngo-2017; 26 (4): 614-621. IINKCUKACHA: 27999144 www.ncbi.nlm.nih.gov/pubmed/27999144

UJohnson DH, uKisiel JB, uBurger KN, et al. Uvavanyo lwe-multitarget stool DNA: ukusebenza kweklinikhi kunye nefuthe kwisivuno kunye nomgangatho wekholososcopy yovavanyo lomhlaza ongalunganga. Isisu endosc. Ngo-2017; 85 (3): 657-665.e1. IINKCUKACHA: 27884518 www.ncbi.nlm.nih.gov/pubmed/27884518.

Iwebhusayithi yeNational Comprehensive Cancer Network (NCCN). Izikhokelo zoqheliso lwezonyango kwi-oncology (Izikhokelo ze-NCCN) Ukuvavanywa komhlaza ongalunganga. Inguqulelo 1.2018. www.nccn.org/professionals/physician_gls/pdf/colorectal_screening.pdf. Ukuhlaziywa kwe-Matshi 26, 2018. Ifikeleleke ngoDisemba 1, 2018.

IPrince M, uLester L, i-Chiniwala R, iBerger B.Imvavanyo ezininzi zestool ze-DNA zonyusa ukuvavanywa komhlaza phakathi kwabaguli beMedicare ababengathobeli. Kwihlabathi J Gastroenterol. Ngo-2017; 23 (3): 464-471. IINKCUKACHA: 28210082. www.ncbi.nlm.nih.gov/pubmed/28210082.

Iinkonzo zoThintelo lweeNkonzo zoMsebenzi wase-US. Isiteyitimenti sokugqibela sengcebiso: umhlaza wombala: uhlolo. Nge-Juni 2017. www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/colorectal-cancer-screening2.