Umbhali: Janice Evans
Umhla Wokudalwa: 2 Eyekhala 2021
Hlaziya Umhla: 16 Eyenkanga 2024
Anonim
GRAPEFRUIT I
Ividiyo: GRAPEFRUIT I

Umxholo

Isiqhamo seediliya sisiqhamo se-citrus. Abantu basebenzisa iziqhamo, i-oyile kwiphepha, kunye nezicatshulwa ezivela kwimbewu njengeyeza. Ukukhutshwa kwembewu yegrapefruit kuqhutywa kwimbewu yeziqhamo zomdiliya kunye nomgubo ofunyenwe njengemveliso evela kwimveliso yejusi yeziqhamo. Imifuno yeglycerin yongezwa kwimveliso yokugqibela ukunciphisa i-asidi kunye nokukrakra.

Isiqhamo samagilebhisi sithathwa ngomlomo ukunciphisa umzimba. Isetyenziselwa isifuba, i-cholesterol ephezulu, umhlaza, kunye nezinye iimeko ezininzi, kodwa abukho ubungqina benzululwazi obuxhasa ezi zinto zisetyenziswayo.

Ekutyeni nasekuseleni, i-grapefruit ityiwa njengesiqhamo, ijusi, kwaye isetyenziswa njenge-flavouring component.

Kwimveliso, i-grapefruit yeoyile kunye nokukhutshwa kwembewu kusetyenziswa njengecandelo levumba elimnandi kwiisepha kunye nezithambiso; nanjengokucoca indlu iziqhamo, imifuno, inyama, umphezulu wekhitshi, izitya nokunye.

Kwezolimo, ukukhutshwa kwembewu yeediliya kusetyenziselwa ukubulala iintsholongwane kunye nefungus, ukulwa nokukhula komngundo, ukubulala iiparasites ekutyeni kwezilwanyana, ukugcina ukutya kunye nokubulala iintsholongwane emanzini.

Kubalulekile ukuba ukhumbule ukuba ukusebenzisana kweziyobisi kunye nejusi yeziqhamo zeediliya kubhalwe kakuhle. I-chemistry ye-grapefruit iyahluka ngohlobo, iimeko ezikhulayo, kunye nenkqubo esetyenziselwa ukukhupha incindi. Ngaphambi kokuba ungeze i-grapefruit ekudleni kwakho okanye uluhlu lwakho lwamayeza endalo, jonga kumboneleli wakho wezempilo ukuba ngaba uthatha amayeza.

Amayeza endalo aVimba weDatha Ukusebenza kwexabiso ngokusekwe kubungqina besayensi ngokwala manqanaba alandelayo: Ukusebenza, ukusebenza ngokukuko, okunokwenzeka ukuba kusebenze, okungenzeka kungasebenzi, kunokwenzeka ukungasebenzi, ukungasebenzi, kunye nobungqina obungonelanga bokulinganisa.

Ukulinganiswa kokusebenza kwe I-GRAPEFRUIT zezi zilandelayo:


Inokwenzeka ukuba isebenze ...

  • Ukutyeba kakhulu. Ukuthatha imveliso ethile equkethe iorenji, iorenji yegazi, kunye nezicatshulwa zeediliya kubonakala kunciphisa ubunzima bomzimba kunye namafutha omzimba kubantu abatyebe kakhulu. Olunye uphando lukwabonisa ukuba ukutya iziqhamo ze grapefruit mihla le kunyusa ukuncipha kubantu abatyebe kakhulu.

Akukho bungqina baneleyo bokulinganisa ukusebenza ...

  • Isifo sombefu. Olunye uphando lubonisa ukuba ukutya iziqhamo ze-citrus ezityebileyo ze-citrus, kubandakanya iidiliya kunye nezinye, kunokuphucula ukusebenza kwemiphunga kubantu abane-asthma. Kodwa ezinye izifundo azibonisanga esi sibonelelo.
  • I-eczema (i-atopic dermatitis). Uphando lwakwangoko lubonisa ukuba ukukhutshwa kwembewu ye grapefruit kunokunciphisa ukuqunjelwa, irhasi, kunye nokungonwabi esiswini kubantu abane-eczema. Esi sibonelelo sinokubangelwa sisiphumo seediliya kwiibhaktiriya zamathumbu.
  • Cholesterol ephezulu. Uphando lwakwangoko lubonisa ukuba ukuthatha iprapefruit pectin yonke imihla iiveki ezili-16 kunciphisa i-cholesterol iyonke kunye ne-lipoprotein (LDL okanye "embi") ye-cholesterol ukuya kwi-lipoprotein (HDL okanye "elungileyo") ye-cholesterol xa kuthelekiswa nesiseko.
  • Amanqanaba aphezulu amafutha abizwa ngokuba yi-triglycerides egazini (hypertriglyceridemia). Ukutya i-grapefruit enye ngosuku kubonakala ukunciphisa i-cholesterol iyonke, i-low-density lipoprotein (LDL okanye "embi") ye-cholesterol, kunye namanqanaba e-triglyceride kubantu abanamanqanaba aphezulu e-triglyceride.
  • Iintwala. Uphando lwakwangoko lubonisa ukuba ukusebenzisa ishampu equlathe igrapefruit kwizinwele zabantwana kangangemizuzu eli-10 ukuya kwengama-20 ibulala iintwala. Ukufaka isicelo se-shampoo kwakhona kwiintsuku ezili-10 kamva kunceda ukususa naziphi na izitshixo ezisele.
  • Amabala.
  • Uxinzelelo.
  • Izikhalazo zokugaya kubantu abane-eczema.
  • Ukuqina kwemithambo (atherosclerosis).
  • Intloko ebuhlungu.
  • Usulelo.
  • Ukudinwa kwezihlunu.
  • Ukuthintela umhlaza.
  • Ukukhuthaza ukukhula kweenwele.
  • Unyango.
  • Uxinzelelo.
  • Ukuthambisa ulusu.
  • Usulelo lobufazi igwele.
  • Ezinye iimeko.
Ubungqina obungakumbi buyafuneka ukukala ukusebenza kwesiqhamo somdiliya kwezi zinto zisetyenziswayo.

I-Grapefruit ngumthombo we-vitamin C, ifayibha, i-potassium, i-pectin kunye nezinye izakhamzimba. Ezinye izinto zinokuba nefuthe le-antioxidant elinokunceda ukukhusela iiseli kumonakalo okanye ukunciphisa i-cholesterol.

Akucaci ukuba ioyile inokusebenza njani ekusebenziseni amayeza.

Xa kuthathwa ngomlomo: Isiqhamo seediliya NGOKUKHUSELEKILEYO kwiimali eziqhelekileyo ezisetyenziswa njengokutya kunye UKHUSELEKO OLUNOKWENZEKA xa uthathwa ngomlomo njengeyeza. Kodwa iidiliya OKUNGENZEKA UKHUSELEKILE xa ithathwa ngomlomo izixa ezikhulu.

Ukuba uthatha nawaphi na amayeza, jonga kumboneleli wakho wezempilo ngaphambi kokuba wongeze iidrapefruit ekutyeni kwakho okanye uyisebenzise njengeyeza. Isiqhamo samagilebhisi sinxibelelana noluhlu olude lwamayeza (jonga "Ngaba kukhona unxibelelwano namayeza?" Ngezantsi).

Amanyathelo okhuseleko kunye nezilumkiso:

Ukukhulelwa kunye nokuncancisa: Akonelanga ngokwaziwa malunga nokusetyenziswa kweediliya ngexesha lokukhulelwa kunye nokuncancisa. Hlala kwicala elikhuselekileyo kwaye uphephe ukusetyenziswa.

Umhlaza webele: Kukho inkxalabo malunga nokhuseleko lokusela izixa ezigqithisileyo zejusi yeziqhamo ze grapefruit. Olunye uphando lubonisa ukuba abasetyhini abasemva kwendoda abasebenzisa ikota okanye ngaphezulu kwejusi yeziqhamo zomdiliya yonke imihla bane-25% ukuya kuma-30% amathuba okuba nomhlaza wamabele. Ijusi yamagilebhisi inciphisa indlela i-estrogen ephulwe ngayo emzimbeni kwaye inokunyusa amanqanaba e-estrogen emzimbeni. Uphando olungakumbi luyafuneka ukuqinisekisa ezi ziphumo. Kuze kube yinto eyaziwayo, thintela ukusela ubuninzi bejusi ye-grapefruit, ngakumbi ukuba unomdlavuza webele okanye uphezulu kunomngcipheko wokuphucula umdlavuza webele.

Izifo zezihlunu zentliziyoUkusetyenziswa kwejusi yeziqhamo zomdiliya kunokunyusa ukubakho kwesingqi sentliziyo esingaqhelekanga. Abantu abanezi zifo kufuneka badle ijusi yeziqhamo zeediliya ngokumodareyitha.

IiHormone ezinomdlavuza kunye neemekoUkutya isixa esikhulu seediliya kunokunyusa amanqanaba ehomoni kwaye ke kunyuse umngcipheko weemeko ezibuthathaka zehomoni. Abasetyhini abaneemeko ezibuthathaka zehomoni kufuneka baphephe iidiliya.

Ukubetha kwentliziyo ngokungaqhelekanga: Ukutya isixa esikhulu seediliya okanye ijusi yeediliya kunokubangela ukubetha kwentliziyo ngokungaqhelekanga. Sukusebenzisa i-grapefruit ukuba unale meko.

Mkhulu
Sukuyithatha le indibaniselwano.
Amiodarone (Cordarone)
Ijusi yamagilebhisi inokunyusa ukuba ingakanani i-amiodarone (Cordarone) umzimba uyifunxa. Ukusela ijusi yamagilebhisi ngelixa uthatha i-amiodarone (Cordarone) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga. Gwema ukusela ijusi yamagilebhisi ukuba uthatha i-amiodarone (Cordarone).
UArtemether (Artenam, Paluther)
Umzimba uqhekeza iartemether (Artenam, Paluther) ukuyikhupha. Ijusi yeziqhamo zeediliya inganciphisa ukuba umzimba uphula ngokukhawuleza kangakanani iartemether (Artenam, Paluther). Ukusela ijusi ye grapefruit ngelixa uthatha uartemether (Artenam, Paluther) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zeartemether (Artenam, Paluther). Musa ukusela ijusi ye grapefruit ukuba uthatha iartemether (Artenam, Paluther).
Atorvastatin (Lipitor)
I-Atorvastatin (Lipitor) luhlobo lweyeza lokunciphisa amayeza aziwa njenge "statin." Umzimba uyaphula i-atorvastatin (Lipitor) ukuze uyilahle. Ijusi yamagilebhisi inokunciphisa ngokukhawuleza ukuba umzimba uphula njani i-atorvastatin (Lipitor). Ukusela i-grapefruit juice ngelixa uthatha i-atorvastatin (Lipitor) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zeliyeza.
IBuspirone (BuSpar)
Ijusi yamagilebhisi inokunyusa ukuba ingakanani ibuspirone (BuSpar) umzimba oyifunayo. Ukusela ijusi yeziqhamo zomdiliya ngelixa uthatha ibuspirone (BuSpar) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zebuspirone (BuSpar).
ICarbamazepine (iTegretol)
Ijusi yamagilebhisi inokunyusa ukuba ingakanani icarbamazepine (Tegretol) eyifunxa umzimba. Ukusela ijusi ye grapefruit ngelixa uthatha i-carbamazepine (Tegretol) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-carbamazepine (Tegretol).
ICarvedilol (iCoreg)
Umzimba uyaphula icarvedilol (Coreg) ukuyilahla. Ijusi yeziqhamo zeediliya ibonakala incipha ngokukhawuleza ukuba umzimba uyaphula njani icarvedilol (Coreg). Ukusela ijusi ye grapefruit ngelixa uthatha i-carvedilol (Coreg) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-carvedilol (Coreg).
ICeliprolol (iCelicard)
Isiqhamo somdiliya sibonakala sinciphisa ukuba ingakanani iceliprolol (Celicard) efunxwayo. Oku kunokunciphisa ukusebenza kwe-celiprolol (Celicard). Ukwahlulahlulahlula ulawulo lwe-celiprolol (Celicard) kunye nokusetyenziswa kwesiqhamo somdiliya ubuncinci iiyure ezi-4.
ICisapride (iPropulsid)
Ijusi yamagilebhisi inokunciphisa ukuba umzimba ukhawuleza ususe njani i-cisapride (Propulsid). Ukusela ijusi yeziqhamo zomdiliya ngelixa uthatha i-cisapride (Propulsid) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-cisapride (Propulsid).
ICommipramine (Anafranil)
Umzimba wophula i-clomipramine (Anafranil) ukuze uyilahle. Ijusi yamagilebhisi inokunciphisa ukuba umzimba ukhawuleza ususe njani i-clomipramine (Anafranil). Ukuthatha ijusi yamagilebhisi kunye ne-clomipramine (Anafranil) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-clomipramine (Anafranil).
IClopidogrel (iPlavix)
IClopidogrel (iPlavix) yiprodrug. Iiprrugs kufuneka zenziwe ngumzimba ukuze zisebenze. Isiqhamo samagilebhisi sibonakala sinciphisa ukuba ingakanani i-clopidogrel (Plavix) eyenziwe yasebenza ngumzimba. Oku kunokukhokelela ekunciphiseni ukusebenza kwe-clopidogrel. Musa ukuthatha iidiliya kunye neclopidogrel.
ICyclosporine (iNeoral, iSandimmune)
Isiqhamo samagilebhisi sinokunyusa ukuba ingakanani i-cyclosporine (Neoral, Sandimmune) eyifunxa umzimba. Ukusela ijusi yeziqhamo zomdiliya ngelixa uthatha i-cyclosporine (Neoral, Sandimmune) kunokunyusa iziphumo ebezingalindelekanga ze-cyclosporine.
I-Dextromethorphan (iRobitussin DM, kunye nabanye)
Umzimba uqhekeza i-dextromethorphan (i-Robitussin DM, abanye) ukuyilahla. Isiqhamo samagilebhisi sinokunciphisa ngokukhawuleza ukuba umzimba uphule njani i-dextromethorphan (iRobitussin DM, abanye). Ukusela ijusi yeziqhamo zomdiliya ngelixa uthatha i-dextromethorphan (i-Robitussin DM, abanye) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-dextromethorphan (i-Robitussin DM, abanye).
Estrogens
Umzimba uphula ii-estrogens ukuze uzilahle. Ijusi yamagilebhisi ibonakala inciphisa ukuba umzimba uphula ngokukhawuleza njani ii-estrogens kunye nokwandisa ukuba ingakanani i-estrogen yomzimba oyifunxa. Ukusela ijusi yamagilebhisi ngelixa uthatha ii-estrogens kunokunyusa amanqanaba e-estrogen kunye neziphumo ebezingalindelekanga ezinxulumene ne-estrogen efana nomhlaza webele.

Ezinye iipilisi ze-estrogen zibandakanya i-equine estrogens (Premarin), i-ethinyl estradiol, i-estradiol (i-Climara, i-Vivelle, i-Estring) kunye nezinye.
I-Etoposide (VePesid)
Isiqhamo samagilebhisi sinokunciphisa ukuba ingakanani i-etoposide (VePesid) eyifunxa umzimba. Ukusela ijusi yeziqhamo zomdiliya ngelixa uthatha i-etoposide (VePesid) kunokunciphisa ukusebenza kwe-etoposide (VePesid). Ukuthintela oku kunxibelelana, hlukanisa ukuthatha eli yeza ekutyeni iziqhamo zeediliya ubuncinci iiyure ezi-4.
IHalofantrine
Umzimba uqhekeza i-halofantrine ukuyikhupha. Ijusi yeziqhamo zeediliya kubonakala ngathi iyancipha ukuba umzimba uphula ngokukhawuleza kangakanani i-halofantrine. Ukusela ijusi yamagilebhisi ngelixa uthatha i-halofantrine kunokunyusa amanqanaba e-halofantrine kunye neziphumo ebezingalindelekanga ezinxulunyaniswa ne-halofantrine, kubandakanya ukubetha kwentliziyo okungaqhelekanga.
ILovastatin (Mevacor)
I-Lovastatin (Mevacor) luhlobo lokwehlisa amayeza e-cholesterol eyaziwa ngokuba yi "statin." Umzimba uyaphula i-lovastatin (Mevacor) ukuyikhupha. Ijusi yamagilebhisi inokunciphisa ngokukhawuleza ukuba umzimba uphula njani i-lovastatin (Mevacor). Ukusela i-grapefruit juice ngelixa uthatha i-lovastatin (Mevacor) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zolu nyango.

Amayeza atshintshwe sisibindi (iiCytochrome P450 3A4 (CYP3A4) substrates)
Amanye amayeza atshintshiwe kwaye aphulwe sisibindi. Ijusi yamagilebhisi inokunciphisa ukuba isibindi siwaphula ngokukhawuleza na amayeza. Ukusela ijusi ye grapefruit ngelixa uthatha amayeza athile aphulwe sisibindi kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zamayeza athile. Ngaphambi kokuba uthathe iidiliya, thetha nomboneleli wakho wezempilo ukuba uthatha nawaphi na amayeza atshintshwa sisibindi.

Amanye amayeza atshintshwe sisibindi kubandakanya i-lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), kunye nezinye ezininzi.
Amayeza oxinzelelo lwegazi oluphezulu (iicalcium block blockers)
Ijusi yamagilebhisi inokunyusa ukuba mangaphi amayeza oxinzelelo lwegazi oluphezulu emzimbeni. Ukusela ijusi yamagilebhisi ngelixa uthatha amayeza oxinzelelo lwegazi kunokubangela ukuba uxinzelelo lwegazi luye phantsi kakhulu.

Amanye amayeza oxinzelelo lwegazi aphezulu abandakanya i-nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), kunye nabanye.
Amayeza ashukunyiswa yimpompo kwiiseli (Izinto ze-Organic anion-zokuhambisa iipolypeptide)
Amanye amayeza ahanjiswa ziimpompo kwiiseli. Isiqhamo samagilebhisi sinokutshintsha ukuba zisebenza njani na iimpompo kwaye zinciphise ukuba angakanani amayeza afunxwa ngumzimba. Oku kunokwenza la mayeza asebenze kancinci. Ukuthintela oku kunxibelelana, hlukanisa ukuthatha la mayeza ekutyeni iziqhamo zeediliya ubuncinci iiyure ezi-4.

Amanye ala mayeza ashukunyiswa ziimpompo kwiiseli kubandakanya i-bosentan (Tracleer), celiprolol (Celicard, abanye), etoposide (VePesid), fexofenadine (Allegra), antibiotics fluoroquinolone, glyburide (Micronase, Diabeta), irinotecan (Camptosar), methotrexate , paclitaxel (Taxol), saquinavir (Fortovase, Invirase), rifampin, statins, talinolol, torsemide (Demadex), troglitazone, kunye ne-valsartan (Diovan).
Amachiza anokubangela ukubetha kwentliziyo okungaqhelekanga (iziyobisi ezolula ixesha lokuphumla le-QT)
Isiqhamo samagilebhisi sinokuchaphazela isingqi sentliziyo yakho. Ukuthatha iidiliya kunye namayeza anokubangela ukubetha kwentliziyo ngokungaqhelekanga kunokubangela iziphumo ebezingalindelekanga ezibi, kubandakanya ukubetha kwentliziyo ngokungaqhelekanga.
Amanye amayeza anokubangela ukubetha kwentliziyo ngokungaqhelekanga kubandakanya i-amiodarone (Cordarone), i-disopyramide (i-Norpace), i-dofetilide (iTikosyn), ibutilide (i-Corvert), i-procainamide (i-Pronestyl), i-quinidine, i-sotalol (i-Betapace), i-thioridazine (i-Mellaril) kunye nezinye ezininzi.
Amayeza asetyenziselwa ukuthoba i-cholesterol (Statins)
Umzimba uqhekeza amayeza athile athoba i-cholesterol abizwa ngokuba yi "statins" ukuwasusa. Ijusi yeziqhamo zeediliya inokunciphisa ngokukhawuleza ukuba umzimba uphula njani "ii-statins". Ukusela ijusi yamagilebhisi ngelixa uthatha "ii-statins" ezithile kunokunyusa iziphumo kunye neziphumo zala mayeza.
Isiqhamo samagilebhisi sikhangeleka ngathi siyancipha ngokukhawuleza ukuba umzimba uphula "ii-statins" ezithile kubandakanya i-lovastatin (Mevacor), i-simvastatin (iZocor), kunye ne-atorvastatin (Lipitor).
Imethadone (iDolophine)
Umzimba uyaphula i-methadone (i-Dolophine) ukuyikhupha. Ijusi yamagilebhisi inokunciphisa ukuba umzimba uphula ngokukhawuleza kangakanani imethadone (iDolophine). Ukusela ijusi yeziqhamo zomdiliya ngelixa uthatha imethadone (iDolophine) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zemethadone (iDolophine).
Imethylprednisolone
Umzimba uyaphula i-methylprednisolone ukuze uyilahle. Ijusi yamagilebhisi inokunciphisa ukuba umzimba ukhawuleza ususe njani i-methylprednisolone. Ukusela ijusi yamagilebhisi ngelixa uthatha i-methylprednisolone kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zemethylprednisolone.
IPraziquantel (iBiltricide)
Umzimba uyaphula i-praziquantel (i-Biltricide) ukuyilahla. Ijusi yeediliya iyancipha ukuba umzimba uphula ngokukhawuleza njani ipraziquantel (iBiltricide). Ukusela ijusi ye grapefruit ngelixa uthatha ipraziquantel (Biltricide) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zepraziquantel (Biltricide).
Iquinidine
Umzimba uqhekeza iquinidine ukuyikhupha. Ijusi yamagilebhisi inokunciphisa ukuba umzimba ukhawuleza kangakanani ukulahla iquinidine. Ukusela i-juice ye-grapefruit ngelixa uthabatha i-quinidine kunokunyusa amathuba okuba nemiphumo emibi.
IScopolamine (iTransderm Scop)
Umzimba uqhekeza i-scopolamine ukuyikhupha. Ijusi yamagilebhisi inokunciphisa ngokukhawuleza ukuba umzimba uphule njani i-scopolamine. Ukusela ijusi yamagilebhisi ngelixa uthatha i-scopolamine kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zescopolamine.
Amayeza okuthambisa (i-Benzodiazepines)
Amayeza okuthambisa anokubangela ukulala nokozela. Ijusi yamagilebhisi inokunciphisa ukuba umzimba uphula njani ngokukhawuleza amayeza athile okuthambisa. Ukusela ijusi yamagilebhisi ngelixa uthatha amayeza okuthomalalisa kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zonyango.

Amanye amayeza okuthomalalisa (i-benzodiazepines) anokusebenzisana nejusi yeziqhamo zibandakanya i-diazepam (Valium), midazolam (iVersed), i-quazepam (iDoral), kunye ne-triazolam (Halcion).
ISildenafil (Viagra)
Umzimba wophula i-sildenafil (Viagra) ukuze uyilahle. Isiqhamo samagilebhisi sinokunciphisa ukuba umzimba uphula ngokukhawuleza njani i-sildenafil (Viagra). Ukusela ijusi ye grapefruit ngelixa uthatha i-sildenafil (Viagra) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-sildenafil (Viagra).
ISimvastatin (iZocor)
Umzimba wophula i-simvastatin (iZocor) ukuyikhupha. Ijusi yeziqhamo zeediliya inokunciphisa ngokukhawuleza ukuba umzimba uphula njani i-simvastatin (iZocor). Ukusela ijusi ye grapefruit ngelixa uthatha i-simvastatin (Zocor) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zeli yeza.

ITacrolimus (iPrograf)
Umzimba uyaphula itacrolimus (Prograf) ukuyilahla. Isiqhamo samagilebhisi sinokunciphisa ngokukhawuleza ukuba umzimba uphula njani i-tacrolimus (Prograf).Ukutya i-grapefruit okanye ukusela i-juice ye-grapefruit ngelixa uthatha i-tacrolimus (Prograf) kunokunyusa imiphumo kunye nemiphumo emibi ye-tacrolimus (Prograf). Gwema ukutya i-grapefruit okanye ukusela i-juice ye-grapefruit xa uthatha i-tacrolimus.
I-Terfenadine (iSeldane)
I-Grapefruit inokunyusa ukuba ingakanani i-terfenadine (Seldane) efunxwa ngumzimba. Ukusela ijusi yeziqhamo zomdiliya ngelixa uthatha i-terfenadine (Seldane) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-terfenadine (Seldane).
ITicagrelor (Brilinta)
Umzimba uyaphula i-ticagrelor (Brilinta) ukuze uyilahle. Isiqhamo samagilebhisi sinokuhla ngokukhawuleza ukuba umzimba uphula njani i-ticagrelor (Brilinta). Ukusela i-grapefruit juice ngelixa uthatha i-ticagrelor (i-Brilinta) inokunyusa imiphumo kunye nemiphumo emibi ye-ticagrelor (i-Brilinta).
Iphakathi
Lumka ngale nhlanganisela.
IAliskiren (iTekturna, iRasilez)
I-Aliskiren (Tekturna, Rasilez) ishukunyiswa ziimpompo kwiiseli zomzimba. Isiqhamo samagilebhisi sinokutshintsha ukuba zisebenza njani na ezi mpompo kwaye zinciphise ukuba ingakanani i-aliskiren (iTekturna, iRasilez) engena emzimbeni. Oku kunokwenza ukuba eli yeza lingasebenzi kakuhle. Ukuthintela oku kunxibelelana, hlukanisa ukuthatha eli yeza ekutyeni iziqhamo zeediliya ubuncinci iiyure ezi-4.
IBlonanserin (iLonasen)
Umzimba uyayaphula i-blonanserin (Lonasen) ukuyilahla. Isiqhamo samagilebhisi sinokunyusa ukuba yimalini i-blonanserin (Lonasen) umzimba uyifunxa kwaye uyinciphise ngokukhawuleza ukuba umzimba uphelisa njani i-blonanserin (Lonasen). Ukusela i-grapefruit ngelixa uthatha i-blonanserin (Lonasen) kunokunyusa iziphumo ebezingalindelekanga ze-blonanserin (Lonasen).
IBudesonide (i-Entocort, i-UCERIS)
Umzimba uyaphula i-budesonide (Pulmicort) ukuze uyilahle. Isiqhamo samagilebhisi sinokukhohlisa ukuba umzimba ukhawuleza ususe njani i-budesonide (Pulmicort). Ukusela i-grapefruit ngelixa uthatha i-budesonide (Pulmicort) kunokunyusa iziphumo ebezingalindelekanga zebudesonide (Pulmicort).
Icaffeine
Umzimba uyayaphula icaffeine ukuze uyilahle. Isiqhamo samagilebhisi sinokukhohlisa ukuba umzimba ukhawuleza ulahle njani icaffeine. Ukusela i-grapefruit ngelixa uthatha i-caffeine kunokunyusa iziphumo zecaffeine kubandakanya jitteriness, intloko ebuhlungu kunye nentliziyo ebetha ngamandla.
Colchicine
Umzimba uphula i-colchicine ukuyikhupha. Isiqhamo samagilebhisi sinokunciphisa ukuba umzimba ukhawuleza ususe njani i-colchicine. Kodwa olunye uphando lubonisa ukuba iidrapefruit ayinciphisi ukuba umzimba ulahla ngokukhawuleza kangakanani icolchicine. Kude kube kwaziwa ngakumbi, landela nayiphi na imiyalelo kwileyibhile ye-colchicine enxulumene nokutya iidiliya.
I-Dapoxetine (Priligy)
Umzimba uphula i-dapoxetine (Priligy) ukuze uyilahle. Ijusi yamagilebhisi inokunciphisa ukuba umzimba ukhawuleza ususe njani i-dapoxetine (Priligy). Ukuthatha ijusi yamagilebhisi kunye ne-dapoxetine (Priligy) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-dapoxetine.
Erythromycin
Umzimba uphula i-erythromycin ukuze uyilahle. Isiqhamo samagilebhisi sinokuhla ngokukhawuleza ukuba umzimba uphelisa njani i-erythromycin. Ukuthatha ijusi yamagilebhisi kunye ne-erythromycin kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-erythromycin.
I-Fexofenadine (Allegra)
Isiqhamo samagilebhisi sinokunciphisa ukuba ingakanani i-fexofenadine (Allegra) eyifunxa umzimba. Ukusela ijusi yamagilebhisi ngelixa uthatha i-fexofenadine (Allegra) kunokunciphisa ukusebenza kwe-fexofenadine (Allegra). Ukuthintela oku kunxibelelana, hlukanisa ukuthatha eli yeza ekutyeni iziqhamo zeediliya ubuncinci iiyure ezi-4.
IFluvoxamine (iLuvox)
Ijusi yamagilebhisi inokunyusa ukuba ingakanani i-fluvoxamine (Luvox) umzimba oyifunxa. Ukusela ijusi yamagilebhisi ngelixa uthatha i-fluvoxamine (Luvox) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-fluvoxamine (Luvox).
Itraconazole (Sporanox)
Itraconazole (Sporanox) isetyenziselwa ukunyanga usulelo lomngundo. Ijusi yamagilebhisi inokuchaphazela ukuba ingakanani itraconazole (Sporanox) eyifunxa umzimba. Kodwa akukho lwazi lwaneleyo lokwazi ukuba le ntsebenzo yeyona nto iphambili.
I-Levothyroxine (Synthroid, abanye)
I-Levothyroxine (Synthroid, abanye) ishukunyiswa yimpompo kwiiseli zomzimba. Isiqhamo samagilebhisi sinokutshintsha ukuba zisebenza njani na ezi mpompo kwaye zinciphise ukuba ingakanani i-levothyroxine (Synthroid, abanye) engena emzimbeni. Oku kunokwenza ukuba eli yeza lingasebenzi kakuhle. Ukuthintela oku kunxibelelana, hlukanisa ukuthatha eli yeza ekutyeni iziqhamo zeediliya ubuncinci iiyure ezi-4.
ILosartan (iCozaar)
Isibindi senza i-losartan (Cozaar) ukuba isebenze. Ijusi yeziqhamo zeediliya inokunciphisa ngokukhawuleza ukuba umzimba usebenze njani losartan (Cozaar). Ukusela ijusi ye grapefruit ngelixa uthatha i-losartan (Cozaar) kunokunciphisa ukusebenza kwelosartan.
Amayeza atshintshwe sisibindi (iiCytochrome P450 1A2 (CYP1A2) substrates)
Amanye amayeza atshintshiwe kwaye aphulwe sisibindi. Ijusi yamagilebhisi inokunciphisa ukuba isibindi siwaphula ngokukhawuleza na amayeza. Ukuthatha ijusi yamagilebhisi kunye namanye amayeza aphulwe sisibindi kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zamayeza athile. Ngaphambi kokuba uthathe incindi yesidiliya uthethe nomboneleli wakho wezempilo ukuba uthatha nawaphi na amayeza atshintshwa sisibindi.

Amanye amayeza atshintshwa sisibindi abandakanya i-amitriptyline (Elavil), haloperidol (Haldol), ondansetron (Zofran), propranolol (Inderal), theophylline (Theo-Dur, abanye), verapamil (Calan, Isoptin, abanye), kunye nabanye.
Amayeza atshintshwe sisibindi (iiCytochrome P450 2C19 (CYP2C19) substrates)
Amanye amayeza atshintshiwe kwaye aphulwe sisibindi. Ijusi yamagilebhisi inokunciphisa ukuba isibindi siwaphula ngokukhawuleza na amayeza. Ukuthatha ijusi yamagilebhisi kunye namanye amayeza aphulwe sisibindi kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zamayeza athile. Ngaphambi kokuba uthathe incindi yesidiliya uthethe nomboneleli wakho wezempilo ukuba uthatha nawaphi na amayeza atshintshwa sisibindi.

Amanye amayeza atshintshwa sisibindi aquka i-omeprazole (Prilosec), i-lansoprazole (Prevacid), kunye ne-pantoprazole (Protonix); diazepam (Valium); icarisoprodol (iSoma); i-nelfinavir (iViracept); nabanye.
Amayeza atshintshwe sisibindi (iiCytochrome P450 2C9 (CYP2C9) substrates)
Amanye amayeza atshintshiwe kwaye aphulwe sisibindi. Ijusi yamagilebhisi inokunciphisa ukuba isibindi siwaphula ngokukhawuleza na amayeza. Ukuthatha ijusi yamagilebhisi kunye namanye amayeza aphulwe sisibindi kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zamayeza athile. Ngaphambi kokuba uthathe incindi yesidiliya uthethe nomboneleli wakho wezempilo ukuba uthatha nawaphi na amayeza atshintshwa sisibindi.

Amanye amayeza atshintshwa sisibindi aquka i-diclofenac (Cataflam, Voltaren), ibuprofen (Motrin), meloxicam (Mobic), kunye ne-piroxicam (Feldene); iselecoxib (iCelebrex); umgca we-amitriptyline (Elavil); iwarfarin (Coumadin); glipizide (Glucotrol); losartan (uCozaar); nabanye.
UNadolol (Corgard)
UNadolol (Corgard) ushukunyiswa ziimpompo kwiiseli zomzimba. Isiqhamo samagilebhisi sinokutshintsha ukuba zisebenza njani ezi mpompo kwaye sinciphise ukuba ingakanani i-nadolol (Corgard) engena emzimbeni. Oku kunokwenza ukuba eli yeza lingasebenzi kakuhle. Nangona kunjalo, olunye uphando lubonisa ukuba iidiliya ayichaphazeli ukuba ingakanani nadolol (Corgard) engena emzimbeni. Kude kube kusaziwa okungaphezulu, landela nayiphi na imiyalelo kwilebheli ye-nadolol (Corgard) enxulumene nokutya iziqhamo ze grapefruit.
Nilotinib (Tasigna)
Ijusi yamagilebhisi inokunyusa ukuba ingakanani iNilotinib (Tasigna) eyifunxa umzimba. Ukusela ijusi yamagilebhisi ngelixa uthatha iNilotinib (Tasigna) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga. Gwema ukusela ijusi yamagilebhisi ukuba uthatha iNilotinib (Tasigna).
Ioksijini (Oxycontin)
Umzimba uphula i-oxycodone (Oxycontin) ukuze uyilahle. Ijusi yamagilebhisi inokunciphisa ngokukhawuleza ukuba umzimba uphule i-oxycodone (i-Oxycontin). Ukusela ijusi yamagilebhisi ngelixa uthatha i-oxycodone (Oxycontin) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-Oxycodone (Oxycontin).
IPitavastatin (Livalo)
Umzimba uyaphula i-pitavastatin (Livalo) ukuyikhupha. Ijusi yamagilebhisi inokunciphisa ngokukhawuleza ukuba umzimba uphula njani ipitavastatin (Livalo). Ukusela i-grapefruit juice ngelixa uthatha i-pitavastatin (Livalo) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zeli yeza.

Intshayelelo
Ijusi yamagilebhisi inokunyusa ukuba yimalini na iprimaquine ekhoyo emzimbeni. Akucaci ukuba zeziphi iziphumo ezinokuba nazo. Lumka ngale nhlanganisela.
I-Saquinavir (iFortovase, i-Invirase)
Ukusela ijusi yeziqhamo ze grapefruit kunokunyusa ukuba ingakanani i-saquinavir (Fortovase, Invirase) umzimba oyifunxa. Ukusela ijusi ye grapefruit ngelixa uthatha i-saquinavir (Fortovase, i-Invirase) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-saquinavir.
ISertraline (iZoloft)
Umzimba uqhekeza i-sertraline ukuyikhupha. Isiqhamo samagilebhisi sinokunciphisa ngokukhawuleza ukuba umzimba uphula njani i-sertraline. Ukusela i-grapefruit juice ngelixa uthatha i-sertraline kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-sertraline.
I-Sunitinib (Sutent)
Umzimba uphula i-sunitinib (Sutent) ukuze uyilahle. Ijusi yamagilebhisi inokunciphisa ngokukhawuleza ukuba umzimba uphule njani i-sunitinib (i-Sutent). Ukusela ijusi yamagilebhisi ngelixa uthatha i-sunitinib (Sutent) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-sunitinib (Sutent). Kodwa olunye uphando lubonisa ukuba isiphumo se grapefruit kwi sunitinib (Sutent) ayisiyiyo inkxalabo enkulu. Kude kube kwaziwa ngakumbi, landela nayiphi na imiyalelo kwelebheli yesunitinib (Sutent) enxulumene nokutya iziqhamo zomdiliya.
UTalinolol
Ijusi yamagilebhisi inokunciphisa ubuninzi be-talinolol ekhoyo emzimbeni. Ukusela i-juice ye-grapefruit kunye ne-talinolol kunokunciphisa imiphumo ye-talinolol.
Ithiophylline
Ukusela ijusi yamagilebhisi kunokunciphisa iziphumo ze-theophylline. Akukho lwazi lwaneleyo lokwazi ukuba oku kuyinkxalabo enkulu.
ITolvaptan (iSamsca)
Umzimba wophula i-tolvaptan (Samsca) ukuyikhupha. Isiqhamo samagilebhisi sinokunciphisa ukuba umzimba uphula ngokukhawuleza kangakanani i-tolvaptan (Samsca). Ukusela ijusi yeziqhamo zomdiliya ngelixa uthatha i-tolvaptan (iSamsca) kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga ze-tolvaptan (Samsca).
IWarfarin (Coumadin)
IWarfarin (Coumadin) isetyenziselwa ukucothisa ukujiya kwegazi. Ukusela i-juice ye-grapefruit kunokunyusa imiphumo ye-warfarin (i-Coumadin) kunye nokwandisa amathuba okugubha kunye nokuphuma kwegazi. Qiniseka ukuba igazi lakho lihlolwe rhoqo. Umthamo we-warfarin yakho (Coumadin) unokufuna ukutshintsha.
Incinci
Jonga olu dibaniso.
IAcebutolol (iCandelo)
I-Acebutolol (Sectral) ishukunyiswa yimpompo kwiiseli zomzimba. Isiqhamo samagilebhisi sinokutshintsha ukuba zisebenza njani na ezi mpompo kwaye zinciphise ukuba ingakanani i-acebutolol (Sectral) efunxwa ngumzimba. Oku kunokwenza ukuba eli yeza lingasebenzi kakuhle. Ukuthintela oku kunxibelelana, hlukanisa ukuthatha eli yeza ekutyeni iziqhamo zeediliya ubuncinci iiyure ezi-4.
I-Amprenavir (iAgenerase)
Isiqhamo samagilebhisi sinokunciphisa kancinci ukuba yimalini i-amprenavir (Agenerase) ethathwa ngumzimba. Kodwa le ntsebenzo ayisiyiyo inkxalabo enkulu.
Licorice
Ukusela i-juice ye-grapefruit xa uthatha i-licorice kunokunyusa amandla e-licorice okubangela ukupheliswa kwe-potassium.
Igwele elibomvu
I-Grapefruit (ijusi okanye iziqhamo) itshintsha indlela umzimba owenza ngayo igwele elibomvu. Isiqhamo samagilebhisi sinokunyusa inani le-lovastatin kwimvubelo ebomvu egazini.
Indudumo uthixo umdiliya
Umdiliya uthixo umdiliya uqulethe i-triptolide. Umzimba uqhekeza i-triptolide ukuze uyisuse. Isiqhamo samagilebhisi sinokunciphisa ngokukhawuleza ukuba umzimba uphula njani i-triptolide. Ukusela ijusi yeziqhamo ze grapefruit ngelixa uthatha isidiliya uthixo umdiliya oqukethe i-triptolide kunokunyusa iziphumo kunye neziphumo ebezingalindelekanga zothixo weendudumo.
Amanzi eetoni
Isiqhamo somdiliya sinokuphazamisa indlela umzimba owenza ngayo iquinine equlethwe kumanzi eetoni. Abantu abanesingqisho sentliziyo (i-QT syndrome ende, umzekelo) kufuneka bakuphephe ukuthatha iidiliya kunye namanzi eetoni kunye, kuba indibaniselwano inokuba mandundu imeko yeentliziyo zabo.
Isiselo somdiliya
Ijusi yamagilebhisi inokunciphisa ukuba isibindi siwaphula ngokukhawuleza na amayeza. Oku kunokunyusa iziphumo ebezingalindelekanga zala mayeza. Ukongeza iwayini ebomvu kumxube kunokunyusa ezi ziphumo bezingalindelekanga nangakumbi. Iwayini emhlophe, nangona kunjalo, ayibonakali inxibelelana ne-grapefruit okanye amayeza aphulwe sisibindi.
La machiza alandelayo afundwe kuphando lwezesayensi:

NGOMLOMO:
  • Ukutyeba kakhuluI-450-700 mg yemveliso ethile equkethe i-orenji emnandi, iorenji yegazi, kunye nezicatshulwa zegrapefruit kabini yonke imihla kwiiveki ezili-12 zisetyenzisiwe. Ukutya isiqingatha se-grapefruit kathathu yonke imihla, ukusela ii-ounces eziyi-8 zejusi yegrape yeziqhamo kathathu yonke imihla, okanye ukuthatha iicapsule eziqukethe i-grapefruit epheleleyo yomile kangange-500 mg kathathu ngaphambi kokutya iiveki ezili-12 nayo isetyenzisiwe.
Bioflavonoid Complex, Bioflavonoid Concentrate, Bioflavonoid Extract, Bioflavonoids, Bioflavonoïdes, Bioflavonoïdes d'grume, Citrus Bioflavones, Citrus Bioflavonoid, Citrus Bioflavonoid Extract, ICitrus Bioflavonoids, iCitrus Flavones, iSitrasi iRisithsisi eCitrus, Cinezela i-oli yeGrapefruit, iComplexe Bioflavonoïde, iComplexe Bioflavonoïde de Pamplemousse, iConcentré de Bioflavonoïde, i-CSE, i-Oyile yeGrapefruit, iSitayile seBioflavonoïde. 'Agrume, Grapefruit Bioflavonoid Complex, Grapefruit Extract, Grapefruit Oil, Grapefruit Seed Extract, Grapefruit Seed Glycerate, GSE, Huile de Pamplemousse, Huile de Pamplemousse Pressée à Froid, Pamplemousse, Pamplemousse Rose, Paradisffel, eGrapefom, I-oyile yaseShaddock, isicatshulwa esisemgangathweni seGrapefruit, eToronja.

Ukuze ufunde okungakumbi malunga nokubhalwa kweli nqaku, nceda ubone Amayeza endalo aVimba weDatha indlela yokusebenza.


  1. U-Ershad M, Cruz MD, Mostafa A, Mckeever R, uVearrier D, uGreenberg MI. I-opioid toxidrome elandela ukusetyenziswa kwejusi yeziqhamo xa kusenziwa ugcino lwe-methadone. J Addict Med 2019; [Epub ngaphambi koshicilelo]. Jonga i-abstract.
  2. UChorin E, uHochstadt A, uGranot Y, et al. Ijusi yamagilebhisi yandisa ixesha le-QT lamavolontiya asempilweni kunye nezigulana ezine-QT syndrome ende. Isingqi sentliziyo. 2019.pii: S1547-527130368-6. Jonga i-abstract.
  3. UChang DW, uWang ZZ, uHu HT, et al. Iziphumo zokutya kunye nejusi yeediliya kwiidosi enye ye-pharmacokinetics ye-blonanserin kwizifundo ezinempilo zaseTshayina. I-Eur J Clin Pharmacol. Ngo-2018; 74: 61-67. Jonga i-abstract.
  4. ISantes-Palacios R, iRomo-Mancillas A, iCamacho-Carranza R, i-Espinosa-Aguirre JJ. Ukuthintela abantu kunye ne-rat CYP1A1 enzyme ngezixhobo zejusi yeziqhamo. Ityhefu. Ngo-2016 uSep 6; 258: 268-75. Jonga i-abstract.
  5. UKawaguchi-Suzuki M, uNasiri-Kenari N, uShuster J, et al. Iziphumo zokusetyenziswa kwejusi yamagilebhisi yegrapefruit esezantsi-furanocoumarin kwi-midazolam pharmacokinetics. J eKliniki kwi-Pharmacol. Ngo-2017 Mar; 57: 305-11. Jonga i-abstract.
  6. UMelough MM, uVance TM, uLee SG, et al. I-Furocoumarin kinetics kwi-plasma kunye nomchamo wabantu abadala abasempilweni kulandela ukusetyenziswa kwesiqhamo seediliya (i-citrus Paradise Macf.) Kunye nejusi yeziqhamo. J Agric Ukutya Chem. I-2017 Mar 29 [Epub ngaphambi koshicilelo] Jonga i-abstract.
  7. UJia Y, Liu J, Xu J. Impembelelo yejusi yeziqhamo zegrape kwi-pharmacokinetics ye-triptolide kwiigundane zejusi yeziqhamo kwiimpembelelo ze-triptolide. Xenobiotica. Ngo-2017 ngoMatshi 16: 1-5. Jonga i-abstract.
  8. I-Abdlekawy KS, i-Donia AM, i-Elbarbry F. Iziphumo zesidiliya kunye neerharnate kwiipropathi ze-pharmacokinetic ze-dapoxetine kunye ne-midazolam kwizifundo ezisempilweni. I-Eur J yeziyobisi iMetab Pharmacokinet. Ngo-2017 uJuni; 42: 397-405. Jonga i-abstract.
  9. UTsuji H, u-Ohmura K, uNakashima R, et al. Ukusebenza kunye nokukhuseleka kokutya kwejusi yamagilebhisi okuhamba nonyango lwe-tacrolimus kwizigulana ezinesifo kwizicwili. Ngaphakathi Med. Ngo-2016; 55: 1547-52. Jonga i-abstract.
  10. I-Hung WL, i-Suh JH, i-Wang Y. I-Chemistry kunye neziphumo zempilo ze-furanocoumarins kwi-grapefruit. J Ukutya iziyobisi. Ngo-2017 uJan; 25: 71-83. Jonga i-abstract.
  11. UMouly S, uLloret-Linares C, uSellire PO, uSene D, uBergmann JF. Ngaba ukubaluleka kweklinikhi yokunxibelelana nokutya iziyobisi kunye neziyobisi kunqunyulwa kwijusi yeziqhamo ze grapefruit kunye ne-Saint-John's Wort? IPharmacol Res. Ngo-2017 kuMatshi; 118: 82-92. Jonga i-abstract.
  12. Ibailey DG. Ukuxela kwangaphambili ukubaluleka kweklinikhi yokunxibelelana neziyobisi kunye neyeza: inkqubo enzima. J kwiKlinikhi yoNyango. Ngo-2017 ngoMatshi; 42: 125-27. Jonga i-abstract.
  13. UDallas C, uGerbi A, uElbez Y, uCaillard P, uZamaria N, uCloarec M.Uvavanyo lwezonyango ukuvavanya ukusebenza kunye nokukhuseleka kwe-citrus polyphenolic extract of red orange, grapefruit, and orange (Sinetrol-XPur) kulawulo lobunzima kunye neeparitha zemetabolic. kubantu abatyebileyo abasempilweni. Phytother Res. NgoFebruwari 2014; 28: 212-8. Jonga i-abstract.
  14. UDallas C, uGerbi A, uTenca G, uJuchaux F, uBernard FX. Impembelelo yeLipolytic yesicatshulwa se-polyphenolic esomileyo se-orenji ebomvu, iidiliya, iorenji (SINETROL) kumanqatha omzimba womntu adipocytes. Indlela yokusebenza ngokuthintela i-cAMP-phosphodiesterase (PDE). Unyango lwezonyango. Ngo-2008 u-Okthobha; 15: 783-92. Jonga i-abstract.
  15. UDahan A, iAmidon GL. Ijusi yeziqhamo zeediliya kunye neendawo zayo zokunyusa ukufunxwa kwamathumbu emathunjini: ukuhlangana okunobungozi kunye nendima ye-p-glycoprotein. KwiFarm Res. Ngo-2009 kuMatshi; 26: 883-92. Jonga i-abstract.
  16. IGoldbart A, Cinezela J, Sofer S, Kapelushnik J.Kufuphi nokubulala i-colchicine enxilisayo emntwaneni. Ingxelo yetyala. I-Eur J iPediatr. Ngo-2000; 159: 895-7. Jonga i-abstract.
  17. UPeterson JJ, uBeecher GR, uBhagwat SA, et al. I-Flavanones kwisiqhamo samagilebhisi, iilamuni, kunye neelime: Ukuhlanganiswa kunye nokuphononongwa kwedatha kuncwadi lohlalutyo. Uhlalutyo lweComp yokutya. Ngo-2006; 19: S74-S80.
  18. IXiao YJ, Hu M, Tomlinson B. Iziphumo zejusi yeziqhamo kwi-cortisol metabolism kwizifundo zesilisa zaseTshayina ezisempilweni. Ukutya iChem Toxicol. NgoDisemba ka-2014; 74: 85-90. Jonga i-abstract.
  19. van Erp NP, Baker SD, Zandvliet AS, Ploeger BA, den Hollander M, Chen Z, den Hartigh J, König-Quartel JM, Guchelaar HJ, Gelderblom H.Ukunyuka okwandisiweyo kokuvezwa kwelanga ngejusi yeziqhamo. Umhlaza Chemother Pharmacol. Ngo-2011 Mar; 67: 695-703. Jonga i-abstract.
  20. I-Tapaninen T, i-Neuvonen PJ, i-Niemi M. Ijusi ye-Grapefruit inciphisa kakhulu ukubonwa kwe-OATP2B1 kunye ne-CYP3A4 substrate aliskiren. KwiKlinikhi ye-Pharmacol Ther. NgoSeptemba 2010; 88: 339-42. Jonga i-abstract.
  21. Tanaka S, Uchida S, Miyakawa S, Inui N, Takeuchi K, Watanabe H, Namiki N. Thelekisa ixesha lokuthintela ijusi yeziqhamo zomdiliya kwi-organic anion-transporting polypeptide kunye ne-cytochrome P450 3A4. IBiol Pharm Bull. Ngo-2013; 36: 1936-41. Jonga i-abstract.
  22. IShoaf SE, iMallikaarjun S, iBricmont P. Iziphumo zejusi yeziqhamo kwi-pharmacokinetics ye-tolvaptan, i-non-peptide arginine vasopressin antagonist, kwizifundo ezisempilweni. I-Eur J Clin Pharmacol. NgoFebruwari 2012; 68: 207-11. Jonga i-abstract.
  23. I-Seidegård J, i-Randvall G, i-Nyberg L, i-Borgå O.Ukusebenzisana kwejusi yeziqhamo zeediliya kunye ne-budesonide yomlomo: isiphumo esilinganayo ekukhululweni kwangoko kunye nokulibaziseka kokukhululwa. Ikhemisi. NgoJulayi 2009; 64: 461-5. Jonga i-abstract.
  24. I-Piccirillo G, Magrì D, Matera S, Magnanti M, Pasquazzi E, Schifano E, Velitti S, Mitra M, Marigliano V, Paroli M, Ghiselli A.Iziphumo zejusi ye-grapefruit ijusi kwi-QT ukwahluka kwizigulana ezine-cardiomyopathy izifundo eziphilileyo. Guqula iRes. Ngo-2008 ngoMeyi; 151: 267-72. Jonga i-abstract.
  25. Nieminen TH, Hagelberg NM, Saari TI, Neuvonen M, Neuvonen PJ, Laine K, Olkkola KT. Ijusi yamagilebhisi yandisa ukubonakaliswa kwe-oxycodone yomlomo. Isiseko seKlinikhi yePhemacol Toxicol. Ngo-2010 ngo-Okthobha; 107: 782-8. Jonga i-abstract.
  26. IMisaka S, Miyazaki N, Yatabe MS, Ono T, Shikama Y, Fukushima T, Kimura J. Pharmacokinetic kunye ne-pharmacodynamic yokunxibelelana kwe-nadolol kunye ne-itraconazole, i-rifampicin kunye nejusi yeziqhamo zeediliya kumavolontiya asempilweni. J eKliniki kwi-Pharmacol. Ngo-2013 Julayi; 53: 738-45. Jonga i-abstract.
  27. Ieiri I, Doi Y, Maeda K, Sasaki T, Kimura M, Hirota T, Chiyoda T, Miyagawa M, Irie S, Iwasaki K, Sugiyama Y. Microdosing clinical clinical: pharmacokinetic, pharmacogenomic (SLCO2B1), kunye nonxibelelwano (ijusi yeediliya) iiprofayili ze-celiprolol elandela i-microdose yomlomo kunye nedosi yokunyanga. J eKliniki kwi-Pharmacol. Ngo-2012 ngoJulayi; 52: 1078-89. Jonga i-abstract.
  28. Hu M, Mak VW, Yin OQ, Chu TT, Tomlinson B. Iziphumo zejusi yeziqhamo kunye ne-SLCO1B1 388A> G polymorphism kwi-pharmacokinetics yepitavastatin. Iziyobisi Metab Pharmacokinet. Ngo-2013; 28: 104-8. Jonga i-abstract.
  29. IHolmberg MT, Tornio A, Neuvonen M, Neuvonen PJ, Backman JT, Niemi M.Ijusi yeziqhamo zeediliya zithintela ukwenziwa kwemetabolism ye-clopidogrel. KwiKlinikhi ye-Pharmacol Ther. Ngo-2014 ngoMatshi; 95: 307-13. Jonga i-abstract.
  30. IHolmberg MT, iTornio A, iJoutsi-Korhonen L, i-Neuvonen M, i-Neuvonen PJ, i-Lassila R, i-Niemi M, i-Backman JT. Ijusi yeziqhamo ze grapefruit ephawuleka kakhulu inyusa ukugxila kweplasma kunye neempembelelo ze-antiplatelet ze-ticagrelor kwizifundo ezisempilweni. UBr J Clin Pharmacol. Ngo-2013 uJuni; 75: 1488-96. Jonga i-abstract.
  31. U-Abdel-Ghaffar F, Semmler M, Al-Rasheid K, Klimpel S, Mehlhorn H. Ukusebenza kwesiqhamo se-grapefruit kwintloko yeentwala: ityala leklinikhi. IParasitol Res. Ngo-2010 uJan; 106: 445-9. Jonga i-abstract.
  32. Ionescu G, Kiehl R, Wichmann-Kunz F, kunye et al. Ukukhutshwa kwembewu ye-citrus yomlomo kwi-atopic eczema: kwi-vitro nakwizifundo ze-vivo kwi-microflora yamathumbu. UJ Orthomol Med 1990; 5: 155-157.
  33. Ameer, B., Weintraub, R. A., Johnson, J. V., Yost, R. A., kunye noRouseff, R. L. Flavanone ukufunxwa emva kwe-naringin, hesperidin, kunye nolawulo lwesitrasi. Iiklinikhi Pharmacol Ther 1996; 60: 34-40. Jonga i-abstract.
  34. I-Pisarik, P.Uxinzelelo lwegazi-lokwehlisa isiphumo sokongeza ijusi yegrapefruit kwi-nifedipine kunye ne-terazosin kwisigulana esinexinzelelo lwexinzelelo lwegazi. IArch Fam. 1996; 5: 413-416. Jonga i-abstract.
  35. UCurhan, G. C., Willett, W. C., Rimm, E. B., Spiegelman, D., kunye noStampfer, M. J. Ukufundwa okulindelweyo kotywala kunye nomngcipheko wamatye ezintso. NdinguJ Epidemiol. 2-1-1996; 143: 240-247. Jonga i-abstract.
  36. UCerda, J. J., Normann, S. J., Sullivan, M. P., Burgin, C. W., Robbins, F. L., Vathada, S., kunye noLeelachaikul, P. Ukuthintelwa kwe-atherosclerosis yi-pectin yokutya kwimicroswine ene-hypercholesterolemia eqhubekayo. Ukujikeleza kwe1994; 89: 1247-1253. Jonga i-abstract.
  37. IBaekey, P.A, Cerda, J. J., Burgin, C.W, Robbins, F. L., Rice, R. W., kunye neBaumgartner, T. G. Grapefruit pectin inhibits hypercholesterolemia kunye atherosclerosis kwiihagu ezincinci. KwiKlinikhi Cardiol 1988; 11: 597-600. Jonga i-abstract.
  38. UMcLundie, A. C. Ukuphulukana namazinyo okuphulukana namazinyo omhlaba kunye nonyango lwawo ngee-porcelain laminates. Ukubuyisela. Ngo-1991; 7: 43-44. Jonga i-abstract.
  39. Guo, LQ, Chen, QY, Wang, X., Liu, YX, Chu, XM, Cao, XM, Li, JH, kunye no Yamazoe, Y. Iindima ezahlukileyo zepummelo furanocoumarin kunye necytochrome P450 3A5 * 3 polymorphism kwisiphelo. kunye nesenzo sefelodipine. I-Curr yeMetab yeziyobisi 2007; 8: 623-630. Jonga i-abstract.
  40. UFerdman, R. M., Ong, P.Y., kunye neCawa, uJ. A. Pectin anaphylaxis kunye nokunxulumana necashew. UAnn. Isifo se-Asma Esibangelwa Kukwalana Neempawu Zomzimba. Ngo-2006; 97: 759-760. Jonga i-abstract.
  41. UFujioka, K., Greenway, F., Sheard, J., kunye no-Ying, Y. Iziphumo ze grapefruit kubunzima kunye ne-insulin ukumelana: ubudlelwane kwisifo se-metabolic syndrome. J Med Ukutya 2006; 9: 49-54. Jonga i-abstract.
  42. Gorinstein, S., Caspi, A., Libman, I., Lerner, HT, Huang, D., Leontowicz, H., Leontowicz, M., Tashma, Z., Katrich, E., Feng, S., kunye I-Trakhtenberg, S. Red grapefruit ngokuqinisekileyo inefuthe kwinqanaba le-serum triglyceride kwizigulana ezinesifo se-coronary atherosclerosis: izifundo kwi-vitro nasebantwini. J Agric Ukutya Chem 3-8-2006; 54: 1887-1892. Jonga i-abstract.
  43. UKumar, A., Teuber, S. S., Naguwa, S., Prindiville, T., kunye noGershwin, M. E. Eosinophilic gastroenteritis kunye ne-citrus-induced urticaria. Iiklinikhi Rev Utyando lwe-Immunol 2006; 30: 61-70. Jonga i-abstract.
  44. UArmanini, D., uCalo, L., kunye noSemplicini, A. Pseudohyperaldosteronism: iindlela ze-pathogenetic. I-Crit Rev yeLebhu yeLebhu ye-Sci 2003; 40: 295-335. Jonga i-abstract.
  45. I-Palermo, M., Armanini, D., kunye ne-Delitala, G. Ijusi yamagilebhisi inqanda i-11beta-hydroxysteroid dehydrogenase kwi vivo, emntwini. Iiklinikhi ze-Endocrinol. (Oxf) 2003; 59: 143-144. Jonga i-abstract.
  46. I-Wangensteen, H., Molden, E., Christensen, H., kunye neMaltud, K. E. Ukuchongwa kwe-epoxybergamottin njenge-CYP3A4 inhibitor kwi-grapefruit peel. I-Eur J Clin Pharmacol 2003; 58: 663-668. Jonga i-abstract.
  47. I-Trinchieri, A., Lizzano, R., Bernardini, P., Nicola, M., Pozzoni, F., Romano, AL, Serrago, MP, kunye noConalanieri, S. Iziphumo zomthwalo omninzi wejusi yeziqhamo zeediliya kwi-urinary excretion ye-citrate kunye nemingcipheko yomchamo yokwenziwa kwamatye e-renal. Dig Dig, Isidibanisi sediski. 2002; 34 iSuppl 2: S160-S163. Jonga i-abstract.
  48. Sardi, A., Geda, C., Nerici, L., kunye noBertello, P. [Rhabdomyolysis kunye noxinzelelo lwegazi olubangelwa kukugqitha kwemamineralocorticoids: ingxelo yetyala]. UAnn Ital Med Int 2002; 17: 126-129. Jonga i-abstract.
  49. I-Bailey, i-DG, i-Dresser, i-GK, i-Kreeft, i-J, i-H, i-Munoz, i-C, i-Freeman, i-D, i-J, kunye ne-Bend, i-J. KwiKlinikhi ye-Pharmacol Ther 2000; 68: 468-477. Jonga i-abstract.
  50. UWason, S., DiGiacinto, J. L., noDavis, M. W. Iziphumo zegrapefruit kunye neejusi zeSeville zeorenji kwiipropathi ze-pharmacokinetic ze-colchicine kwizifundo ezisempilweni. Iiklinikhi zeTher 2012; 34: 2161-2173. Jonga i-abstract.
  51. I-Kiani, J. kunye ne-Imam, S. Z. Ukubaluleka kwamayeza kwijusi yeziqhamo zegrape kunye nokunxibelelana kwayo neziyobisi ezahlukeneyo. Isondlo. J. Ngo-2007; 6: 33. Jonga i-abstract.
  52. Odou, P., Ferrari, N., Barthelemy, C., Brique, S., Lhermitte, M., Vincent, A., Libersa, C., noRobert, H. Grapefruit ukusebenzisana kwejusi-nifedipine: ukubandakanyeka okunokwenzeka kwamanani amaninzi iindlela. J Iiklinikhi zeTherr 2005; 30: 153-158. Jonga i-abstract.
  53. Desta, Z., Kivisto, K. T., Lilja, J., Backman, J. T., Soukhova, N., Neuvonen, P. J., kunye noFlockhart, D. A. Stereoselective pharmacokinetics ye-cisapride kumavolontiya asempilweni kunye nefuthe lokulawulwa okuphindaphindiweyo kwejusi yeziqhamo. UBr J Clin Pharmacol 2001; 52: 399-407. Jonga i-abstract.
  54. I-Kivisto, K., Lilja, J., Backman, J., Neuvonen, P. J. Ukusetyenziswa okuphindaphindiweyo kwejusi yeziqhamo ze grapefruit kwandisa kakhulu ukubonwa kwe-cisapride. Kwiklinikhi ye-Pharmacol Ther 1999; 66: 448-453. Jonga i-abstract.
  55. ILilja, J., Laitinen, K., kunye neNevuvenen, P. J. Iziphumo zejusi yeziqhamo zomdiliya ekufunxweni kwe-levothyroxine. UBr J Clin Pharmacol 2005; 60: 337-341. Jonga i-abstract.
  56. Glaeser, H., Bailey, DG, Dresser, GK, Gregor, JC, Schwarz, UI, McGrath, JS, Jolicoeur, E., Lee, W., Leake, BF, Tirona, RG, kunye noKim, RB Umthuthi othutha iziyobisi ngaphakathi intetho kunye nefuthe lejusi yeziqhamo zomdiliya ebantwini. KwiKlinikhi ye-Pharmacol Ther 2007; 81: 362-370. Jonga i-abstract.
  57. Sigusch, H., Henschel, L., Kraul, H., Merkel, U., kunye noHoffmann, A. Ukusilela kwesiphumo sejusi yeziqhamo zeediliya kwi-diltiazem bioavailability kwizifundo eziqhelekileyo. Pharmazie 1994; 49: 675-679. Jonga i-abstract.
  58. I-Paine, MF, Widmer, WW, Hart, HL, Pusek, SN, Beavers, KL, Criss, AB, Brown, SS, Thomas, BF, kunye neWatkins, PB Ijusi yamagilebhisi engena-furanocoumarin iseka ii-furanocoumarins njengabalamli besidiliya Ukudibana kwencindi-felodipine. NdinguJ J Clin 2006; 83: 1097-1105. Jonga i-abstract.
  59. Ewe, G. C., Stanley, D. L., Pessa, L. J., Dalla, Costa T., Beltz, S. E., Ruiz, J., kunye noLowenthal, D. T. Iziphumo zejusi yeziqhamo zeediliya kwigazi le-cyclosporin. ILancet 4-15-1995; 345: 955-956. Jonga i-abstract.
  60. Schwarz, U. I., Johnston, P. E., Bailey, D. G., Kim, R. B., Mayo, G., kunye noMilstone, A. Impembelelo yeziselo ezinxilisayo zesitrasi ezinxulumene nejusi yeziqhamo zomdiliya kwi-ciclosporin. UBr J Clin Pharmacol 2006; 62: 485-491. Jonga i-abstract.
  61. U-Lee, M., Min, D., Ku, Y. M., noFlanigan, M. Iziphumo zejusi yeziqhamo kwi-pharmacokinetics ye-microemulsion cyclosporine kwizifundo zase-Afrika zaseMelika xa kuthelekiswa nezifundo zeCaucasian: ngaba umahluko kubuhlanga ubalulekile? J Clin Pharmacol 2001; 41: 317-323 (PubMed) (Umnqamlezo) Jonga i-abstract.
  62. Ku, Y. M., Min, D., kunye noFlanigan, M. Iziphumo zejusi yeziqhamo kwi-pharmacokinetics ye-microemulsion cyclosporine kunye nemetabolite yayo kumavolontiya asempilweni: ngaba umahluko wokwenziwa kubalulekile? J Clin Pharmacol 1998; 38: 959-965. Jonga i-abstract.
  63. UDucharme, M. P., Warbasse, L.H, no-Edwards, D. J.Ukuchithwa kwe-cyclosporine yomlomo kunye nomlomo emva kolawulo ngejusi yeziqhamo. KwiKlinikhi ye-Pharmacol Ther 1995; 57: 485-491. Jonga i-abstract.
  64. Bistrup, C., Nielsen, F.T, Jeppesen, UE, kunye noDieperink, H. Iziphumo zejusi yeziqhamo zegrape kwi-Sandimmun Neoral yokufakwa ngaphakathi kwabaamkeli be-allograft abazinzileyo. Ukucofa iNephrol. 2001; 16: 373-377. Jonga i-abstract.
  65. Uno, T., Ohkubo, T., Motomura, S., kunye no-Sugawara, K. Iziphumo zejusi yeziqhamo zomdiliya ekubekweni kwee-enantiomers ze-manidipine kwizifundo ezisempilweni. UBr J Clin Pharmacol 2006; 61: 533-537. Jonga i-abstract.
  66. URashid, J., McKinstry, C., Renwick, A. G., Dirnhuber, M., Waller, D. G., noGeorge, C. F. Quercetin, in vitro inhibitor ye-CYP3A, ayinalo igalelo kunxibelelwano phakathi kwe-nifedipine kunye nejusi yeziqhamo. UBr J Clin Pharmacol 1993; 36: 460-463. Jonga i-abstract.
  67. Iisoni, i-PA, iiVogels, i-BA, i-Roosemalen, i-MC, iSchoemaker, i-HC, i-Uchida, i-E, i-Edgar, i-B, i-Lundahl, i-J, i-Cohen, i-AF kunye ne-Breimer, i-DD ijusi yeediliya kunye ne-cimetidine inhibit metabolism ye-nitrendipine . KwiKlinikhi ye-Pharmacol Ther 1991; 50: 394-403. Jonga i-abstract.
  68. URashid, T. J., Martin, U., Clarke, H., Waller, D. G., Renwick, A. G., noGeorge, C. F. Izinto ezichaphazela ukungafumaneki ngokupheleleyo kwe-nifedipine. UBr J Clin Pharmacol 1995; 40: 51-58. Jonga i-abstract.
  69. I-Lundahl, J., i-Conth, i-C., I-Edgar, i-B, kunye ne-Johnsson, i-G.Ubudlelwane phakathi kwexesha lokutya i-juice ye-grapefruit kunye nefuthe layo kwi-pharmacokinetics kunye ne-pharmacodynamics ye-felodipine kwizifundo ezinempilo. I-Eur J Clin Pharmacol 1995; 49 (1-2): 61-67. Jonga i-abstract.
  70. I-Lundahl, J., i-Conth, i-C., I-Edgar, i-B, kunye ne-Johnsson, i-G Iziphumo zejusi yeziqhamo yokungenisa-i-pharmacokinetics kunye ne-haemodynamics ye-felodipine efakwa ngaphakathi nangomlomo kumadoda aphilileyo. I-Eur J Clin Pharmacol 1997; 52: 139-145. Jonga i-abstract.
  71. IHashimoto, K., Shirafuji, T., Sekino, H., Matsuoka, O., Sekino, H., Onnagawa, O., Okamoto, T., Kudo, S., kunye noAzuma, J. Ukudibana kweencindi zesitrasi kunye ipranidipine, i-1,4-dihydropyridine calcium antagonist, kwizifundo ezisempilweni. I-Eur J Clin Pharmacol 1998; 54 (9-10): 753-760. Jonga i-abstract.
  72. UFuhr, U., Maier-Bruggemann, A., Blume, H., Muck, W., Unger, S., Kuhlmann, J., Huschka, C., Zaigler, M., Rietbrock, S., kunye noStaib, I-AH Ijusi yeediliya inyusa i-nimodipine bioavailability. I-Int J Clin Pharmacol Ther 1998; 36: 126-132. Jonga i-abstract.
  73. Goosen, TC, Cillie, D., Bailey, DG, Yu, C., He, K., Hollenberg, PF, Woster, PM, Cohen, L., Williams, JA, Rheeders, M., kunye noDijkstra, HP Bergamottin igalelo kwi-grapefruit juice-felodipine intsebenziswano kunye nesimo kubantu. KwiKlinikhi ye-Pharmacol Ther 2004; 76: 607-617. Jonga i-abstract.
  74. U-Edgar, B., Bailey, D., Bergstrand, R., Johnsson, G., kunye no-Such, C. G. Iziphumo ezibi zokusela ijusi yeziqhamo ze-grapefac kwi-pharmacokinetics kunye ne-dynamics ye-felodipine-kunye nokubaluleka kwayo kweklinikhi. I-Eur J Clin Pharmacol 1992; 42: 313-317. Jonga i-abstract.
  75. UChristensen, H., Asberg, A., Holmboe, A.B, kunye noBerg, K. J.Ukulawulwa kwejusi yeziqhamo zeediliya inyusa ukubonakaliswa kwenkqubo ye-diltiazem kumavolontiya asempilweni. I-Eur J Clin Pharmacol 2002; 58: 515-520 (PubMed) (Umnqamlezo) Jonga i-abstract.
  76. I-Bailey, i-DG, i-Arnold, i-J, i-Bend, i-J, i-T, i-T, i-T, kunye ne-Spence, i-J. D. Ukuxhamla i-juice-felodipine ukusebenzisana: ukuveliswa kwakhona kunye nokubonakaliswa kokuveliswa kweziyobisi. UBr J Clin Pharmacol 1995; 40: 135-140. Jonga i-abstract.
  77. I-Bailey, i-DG, i-Arnold, i-J, i-Munoz, i-C, kunye ne-Spence, i-J. KwiKlinikhi ye-Pharmacol Ther 1993; 53: 637-642. Jonga i-abstract.
  78. Schwarz, U. I., Seemann, D., Oertel, R., Miehlke, S., Kuhlisch, E., Fromm, M. F., Kim, R. B., Bailey, D. G., kunye noKirch, W.Ukufakwa kwejusi yeGrapefruit kuyinciphisa kakhulu i-talinolol bioavailability. KwiKlinikhi ye-Pharmacol Ther 2005; 77: 291-301. Jonga i-abstract.
  79. USugimoto, K., Araki, N., Ohmori, M., Harada, K., Cui, Y., Tsuruoka, S., Kawaguchi, A., noFujimura, A. Unxibelelwano phakathi kwencindi yediliya kunye neziyobisi ezilaliswayo: uthelekiso triazolam kunye nequazepam. I-Eur J Clin Pharmacol 2006; 62: 209-215. Jonga i-abstract.
  80. I-Hugen, PW, Burger, DM, Koopmans, PP, Stuart, JW, Kroon, FP, van Leusen, R., kunye no-Hekster, YA Saquinavir soft-gel capsules (Fortovase) zinika ukuvezwa okuncinci kunokuba bekulindelwe, nasemva kokuba amanqatha aphezulu isidlo sakusasa. Kwihlabathi lezeMpilo i-2002; 24: 83-86. Jonga i-abstract.
  81. I-Culm-Merdek, KE, von Moltke, LL, Gan, L., Horan, KA, Reynolds, R., Harmatz, JS, Inkundla MH, kunye neGreenblatt, i-DJ Iziphumo zokuvezwa okwandisiweyo kwijusi yeziqhamo zegrape kwi-cytochrome P450 3A umsebenzi ebantwini : uthelekiso ne-ritonavir. KwiKlinikhi ye-Pharmacol Ther 2006; 79: 243-254. Jonga i-abstract.
  82. Cuong, B.T, Binh, V. Q., Dai, B., Duy, D. N., Lovell, C. M., Rieckmann, K. H., no-Edstein, M. D. Ngaba isini, ukutya okanye ijusi yeziqhamo zeediliya ziyayitshintsha i-pharmacokinetics yeprimaquine kwizifundo ezisempilweni? UBr J Clin Pharmacol 2006; 61: 682-689. Jonga i-abstract.
  83. ICharbit, B., Becquemont, L., Lepere, B., Peytavin, G., kunye neFunck-Brentano, C.Ukusebenzisana kweFarmacokinetic kunye ne-pharmacodynamic phakathi kwencindi yeziqhamo zeediliya kunye ne halofantrine. KwiKlinikhi ye-Pharmacol Ther 2002; 72: 514-523. Jonga i-abstract.
  84. Lilja, J., Neuvonen, M., kunye Neuvonen, P. J. Iziphumo zokusetyenziswa kwesiqhelo sejusi yeziqhamo kwi-pharmacokinetics ye-simvastatin. UBr J Clin Pharmacol 2004; 58: 56-60. Jonga i-abstract.
  85. Ando, ​​H., Tsuruoka, S., Yanagihara, H., Sugimoto, K., Miyata, M., Yamazoe, Y., Takamura, T., Kaneko, S., kunye noFujimura, A. Iziphumo zejusi yeziqhamo zeediliya I-pharmacokinetics yepitavastatin kunye neatorvastatin. UBr J Clin Pharmacol 2005; 60: 494-497. Jonga i-abstract.
  86. UClifford, C. P., Adams, D., Murray, S., Taylor, G. W., Wilkins, M. R., Boobis, A. R., noDavies, D. S. Iziphumo zentliziyo ye-terfenadine emva kokuthintela imetabolism yayo ngejusi yeziqhamo. I-Eur J Clin Pharmacol 1997; 52: 311-315. Jonga i-abstract.
  87. I-Benton, R. E., Honig, P.K, Zamani, K., Cantilena, L. R., kunye neWoosley, R. L. Ijusi yamagilebhisi eguqula iterfenadine pharmacokinetics, ekhokelela ekwandiseni ukuphindwaphindeka kwi-electrocardiogram. Iiklinikhi zeFarmacol Ther 1996; 59: 383-388. Jonga i-abstract.
  88. I-Kawakami, M., Suzuki, K., Ishizuka, T., Hidaka, T., Matsuki, Y., kunye no-Nakamura, H. Iziphumo zejusi yeziqhamo zeediliya kwi-pharmacokinetics ye-itraconazole kwizifundo ezisempilweni. I-Int J Clin Pharmacol Ther 1998; 36: 306-308. Jonga i-abstract.
  89. U-Lee, A. J., Chan, W. K., Harralson, A. F., Buffum, J., kunye noBui, B. C. Iziphumo zejusi yeziqhamo zeediliya kwi-sertraline metabolism: i-in vitro nakwisifundo se-vivo. Iiklinikhi zeTher 1999; 21: 1890-1899. Jonga i-abstract.
  90. Min, D. I., Ku, Y. M., Geraets, D. R., kunye no-Lee, H. Iziphumo zejusi yeziqhamo zomdiliya kwi-pharmacokinetics nakwi-pharmacodynamics ye-quinidine kumavolontiya asempilweni. J Clin Pharmacol 1996; 36: 469-476 (PubMed) (Umnqamlezo) Jonga i-abstract.
  91. Libersa, CC, Brique, SA, Motte, KB, Caron, JF, Guedon-Moreau, LM, Humbert, L., Vincent, A., Devos, P., kunye noLhermitte, MA Ukuthintelwa okumangalisayo kwemetabolism ye-amiodarone ebangelwa yincindi yesidiliya . UBr J Clin Pharmacol 2000; 49: 373-378. Jonga i-abstract.
  92. UKupferschmidt, H.H, Ha, H. R., Ziegler, W. H., Meier, P. J., kunye noKrahenbuhl, S. Unxibelelwano phakathi kwencindi yeziqhamo zeediliya kunye ne-midazolam ebantwini. Kwiklinikhi ye-Pharmacol Ther 1995; 58: 20-28. Jonga i-abstract.
  93. IHukkinen, S. K., Varhe, A., Olkkola, K.T, kunye neNuvuvonen, P. J.Ukugxininiswa kwePlasma ye-triazolam kunyuswa ngokungenisa okuhambelana kwencindi yeediliya. Kwiklinikhi ye-Pharmacol Ther 1995; 58: 127-131. Jonga i-abstract.
  94. Andersen, V., Pedersen, N., Larsen, N. E., Sonne, J., kunye noLarsen, S. Amathumbu okuqala apasa imetabolism ye-midazolam kwi-cirrhosis yesibindi -isiphumo sejusi yeziqhamo. UBr J Clin Pharmacol 2002; 54: 120-124. Jonga i-abstract.
  95. USigusch, H., Hippius, M., Henschel, L., Kaufmann, K., kunye noHoffmann, A. Impembelelo yejusi yeziqhamo zeediliya kwi-pharmacokinetics yokukhutshwa kancinci kwe-nifedipine formulation. Pharmazie 1994; 49: 522-524. Jonga i-abstract.
  96. Hollander, AA, van Rooij, J., Lentjes, GW, Arbouw, F., van Bree, JB, Schoemaker, RC, van Es, LA, van der Woude, FJ, kunye noCohen, AF Iziphumo zejusi yeziqhamo ze grapefruit kwi cyclosporine kunye ne-prednisone metabolism ekufakeni kwizigulana. KwiKlinikhi ye-Pharmacol Ther 1995; 57: 318-324. Jonga i-abstract.
  97. Lilja JJ, Raaska K, Neuvonen PJ. Iziphumo zejusi yeziqhamo zeediliya kwi-pharmacokinetics ye-acebutolol. UBr J Clin Pharmacol 2005; 60: 659-63. Jonga i-abstract.
  98. I-Yin OQ, uGallagher N, uLi A, et al. Iziphumo zejusi yeediliya kwi-pharmacokinetics ye-nilotinib kubathathi-nxaxheba abasempilweni. J Ikliniki ye-Pharmacol 2010; 50: 188-94. Jonga i-abstract.
  99. UBenmebarek M, uDevaud C, uGex-Fabry M, et al. Iziphumo zencindi yesidiliya kwi-pharmacokinetics ye-enantiomers ye-methadone. KwiKlinikhi ye-Pharmacol Ther 2004; 76: 55-63. Jonga i-abstract.
  100. UHori H, Yoshimura R, Ueda N, et al. Ukudibana kwejusi yeziqhamo-i-fluvoxamine- ngaba kuyingozi okanye akunjalo? J Iklinikhi yePsychopharmacol 2003; 23: 422-4. Jonga i-abstract.
  101. UYasui N, uKondo T, uFurukori H, et al. Iziphumo zokungenisa okuphindaphindiweyo kwejusi yeediliya kwi-pharmacokinetics enye kunye ne-pharmacokinetics kunye ne-pharmacodynamics ye-alprazolam. I-Psychopharmacology (Berl) 2000; 150: 185-90. Jonga i-abstract.
  102. Iidemon D, Gillotin C, Bonaventure-Paci S, et al. I-pharmacokinetics yedosi enye ye-amprenavir elawulwa ngejusi yeziqhamo. Iiarhente zeAntimicrob Chemother 2002; 46: 1589-90. Jonga i-abstract.
  103. Ulwazi ngemveliso yeCordarone. Imbuyekezo Wyeth Pharmaceuticals, Inc.IPhiladelphia, PA 19101. Septemba 2006.
  104. I-Bailey DG, i-GK yokunxiba, i-Leake BF, i-Kim RB. INaringin yeyona nto iphambili kwaye ikhethiweyo inqanda i-polypeptide 1A2 (OATP1A2) kwijusi yeziqhamo. Iklinikhi ye-Pharmacol Ther 2007; 81: 495-502. Jonga i-abstract.
  105. Ibailey DG. Ijusi yeziqhamo inhibition yokuthatha: uhlobo olutsha lokunxibelelana neziyobisi. UBr J Clin Pharmacol 2010; 70: 645-55. Jonga i-abstract.
  106. IGreenblatt DJ. Uhlalutyo lokunxibelelana kweziyobisi kubandakanya iziyobisi kunye nezixhobo ze-organic anion-transport polypeptides. J Clin Pharmacol 2009; 49: 1403-7. Jonga i-abstract.
  107. Umnxibi GK, Kim RB, Bailey DG. Iziphumo zomthamo wejusi yamagilebhisi kunciphiso lwe-fexofenadine bioavailability: indima enokwenzeka ye-organic anion yokuhambisa iipolypeptides. KwiKlinikhi ye-Pharmacol Ther 2005; 77: 170-7. Jonga i-abstract.
  108. Unxibelelwano olunokubakho lweziyobisi kunye negrapefruit. Ileta ka-Pharmacist / I-Prescriber's Letter 2007; 23: 230204.
  109. UFarkas D, u-Oleson LE, uZhao Y, et al. Incindi yepomegranate ayithinteli ukucocwa kwe-midazolam yomlomo okanye efakwa ngaphakathi, iprosesa yento ye-cytochrome P450-3A: ukuthelekisa nejusi yeziqhamo. J Ikliniki ye-Pharmacol 2007; 47: 286-94. Jonga i-abstract.
  110. UMonroe KR, uMurphy SP, uKolonel LN, uPike MC. Ukufundwa okulindelweyo kokutya iziqhamo zeediliya kunye nomngcipheko womhlaza webele kubafazi abasele besemopopayi Br J Umhlaza 2007; 97: 440-5. Jonga i-abstract.
  111. UZitron E, uScholz E, uOwen RW, et al. Ukongezwa kweQTc ngejusi yeziqhamo zeediliya kunye nesiseko sayo se-pharmacological: Isitishi se-HERG sivalelwe yi-flavonoids. Ukuhamba ngo-2005; 835: 835-8. Jonga i-abstract.
  112. I-Unger M, uFrank A. Ukuzimisela ngaxeshanye kokuthintelwa kwezinto ezinamayeza ezenziweyo kwimisebenzi yee-enzymes ezinkulu ze-cytochrome P450 zisebenzisa i-chromatography engamanzi / i-mass spectrometry kunye ne-automated online extraction. Ukukhawuleza kweMass Communct Spectrom 2004; 18: 2273-81. Jonga i-abstract.
  113. UFukazawa I, Uchida N, Uchida E, Yasuhara H. Iziphumo zejusi yeziqhamo zegrape kwi-pharmacokinetics ye-atorvastatin kunye nepravastatin eJapan. UBr J Clin Pharmacol 2003; 57: 448-55. Jonga i-abstract.
  114. ISullivan DM, iFord MA, iBoyden TW. Ijusi yamagilebhisi kunye nempendulo kwi-warfarin. NdinguJ J wezeMpilo-iSyst Pharm 1998; 55: 1581-3. Jonga i-abstract.
  115. UGaudineau C, Beckerman R, Welbourn S, Auclair K.Uthintelo lwee-enzyme ze-P450 zabantu zizinto ezininzi zokukhutshwa kweGinkgo biloba. I-Biochem Biophys Res Comm 2004; 318: 1072-8. Jonga i-abstract.
  116. I-Bailey DG, isinxibo seGK, iBend JR. I-Bergamottin, ijusi yelamuni, kunye newayini ebomvu njenge-inhibitors ye-cytochrome P450 3A4: uthelekiso kunye nejusi yeziqhamo. KwiKlinikhi ye-Pharmacol Ther 2003; 73: 529-37. Jonga i-abstract.
  117. UDi Marco MP, uEdward DJ, uWainer IW, iLungu lePalamente laseDucharme. Iziphumo zejusi yeziqhamo ze grapefruit kunye ne-seville orange juice kwi-pharmacokinetics ye-dextromethorphan: indima ye-gut CYP3A kunye ne-P-glycoprotein. Ubomi beSayensi 2002; 71: 1149-60. Jonga i-abstract.
  118. IParker RB, iYates CR, uSoberman JE, uLaizure SC. Iziphumo zencindi yediliya kwi-P-glycoprotein yamathumbu: kuvavanyo kusetyenziswa i-digoxin ebantwini. I-Pharmacotherapy 2003; 23: 979-87. Jonga i-abstract.
  119. UShelton MJ, uWynn HE, uHewitt RG, uDiFrancesco R. Iziphumo zejusi yeziqhamo zegrape kwi-pharmacokinetic exposure kwi-indinavir kwizifundo ezine-HIV. J Clin Pharmacol 2001; 41: 435-42. Jonga i-abstract.
  120. Umnxibi GK, Bailey DG, Leake BF, et al. Iziqhamo zejusi zithintela i-organic anion yokuhambisa i-polypeptide-Mediated drug ukuthatha ukuthatha ukunciphisa ukufumaneka ngomlomo kwe-fexofenadine. KwiKlinikhi ye-Pharmacol Ther 2002; 71: 11-20. Jonga i-abstract.
  121. I-Becquemont L, iVerstuyft C, iCrb R, okqhubekayo. Iziphumo zejusi yeziqhamo ze grapefruit kwi-digoxin pharmacokinetics ebantwini. KwiKlinikhi ye-Pharmacol Ther 2001; 70: 311-6. Jonga i-abstract.
  122. I-Bailey DG, isinxibo seGK, iBend JR. I-Bergamottin, ijusi yelamuni, kunye newayini ebomvu njenge-inhibitors ye-cytochrome P450 3A4 yomsebenzi: ukuthelekisa nejusi yeziqhamo ze grapefruit. KwiKlinikhi ye-Pharmacol Ther 2003; 73: 529-37. Jonga i-abstract.
  123. IVeronese ML, uGillen LP, uBurke JP, et al. Ukubonakaliswa kuxhomekeke kuthintelo lwe-CYP3A4 yamathumbu kunye ne-hepatic kwi-vivo ngejusi yeziqhamo ze grapefruit. J Clin Pharmacol 2003; 43: 831-9. . Jonga i-abstract.
  124. URogers JD, uZhao J, uLiu L, et al. Ijusi yamagilebhisi ineziphumo ezincinci kwiziphumo zeplasma ye-lovastatin-ethathwe kwi-3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. KwiKlinikhi ye-Pharmacol Ther 1999; 66: 358-66. Jonga i-abstract.
  125. USchmiedlin-Ren P, u-Edwards DJ, uFitzsimmons ME, et al. Iindlela zokufumaneka komlomo okuphuculweyo kwe-CYP3A4 substrates ngabantu beediliya. Ukuncipha kwe-enterocyte ye-CYP3A4 yoxinzelelo kunye nendlela esekwe ekusebenzeni yi-furanocoumarins. Ukulahlwa kweMetab yeziyobisi 1997; 25: 1228-33. Jonga i-abstract.
  126. U-Edwards DJ, uFitzsimmons ME, uSchuetz EG, et al. 6 ', 7'-Dihydroxybergamottin kwijusi yeziqhamo kunye nejusi ye-Seville ye-orenji: iziphumo kwi-cyclosporine disposition, enterocyte CYP3A4, kunye ne-P-glycoprotein. KwiKlinikhi ye-Pharmacol Ther 1999; 65: 237-44. Jonga i-abstract.
  127. IPenzak SR, Acosta EP, Turner M, okqhubekayo. Iziphumo zejusi yeorenji yaseSeville kunye nejusi yeediliya kwi-indinavir pharmacokinetics. J Clin Pharmacol 2002; 42: 1165-70. Jonga i-abstract.
  128. IGupta MC, iGarg SK, iBadyal D, et al. Iziphumo zejusi yeziqhamo zeediliya kwi-pharmacokinetics ye-theophylline kumavolontiya angamadoda asempilweni. Iindlela zokufumana i-Clin Clin Pharmacol 1999; 21: 679-82. Jonga i-abstract.
  129. IGreenblatt DJ, von Moltke LL, IHarmatz JS. Ixesha lokufumana kwakhona i-cytochrome P450 3A ukusebenza emva kwethamo elinye lejusi yeziqhamo. KwiKlinikhi ye-Pharmacol Ther 2003; 74: 121-29. Jonga i-abstract.
  130. IHermans K, iStockman D, uVan den Branden F. I-Grapefruit kunye ne-tonic: indibaniselwano ebulalayo kwisigulana esine-QT syndrome ende. NdinguJ Med 2003; 114: 511-512.
  131. UReif S, uNicolson M, uBisset D, et al. Iziphumo zokutya kwejusi yamagilebhisi kwi-etoposide bioavailability. I-Eur J Clin Pharmacol 2002; 58: 491-4 .. Jonga i-abstract.
  132. I-Kanazawa S, i-Ohkubo T, i-Sugawara K. Iziphumo zejusi ye grapefruit kwi-pharmacokinetics ye-erythromycin. I-Eur J Clin Pharmacol 2001; 56: 799-803. Jonga i-abstract.
  133. UFuhr U, uMuller-Peltzer H, uKern R, et al. Iziphumo zencindi yediliya kunye nokutshaya kugxininiso lwe-verapamil kwimeko ezinzileyo. I-Eur J Clin Pharmacol 2002; 58: 45-53. Jonga i-abstract.
  134. U-Ebert U, u-Oertel R, u-Kirch W. Impembelelo yesiselo seediliya kwi-scopolamine pharmacokinetics kunye ne-pharmacodynamics kwizifundo ezisempilweni zamadoda nabasetyhini. I-Int J Clin Pharmacol Ther 2000; 38: 523-31. Jonga i-abstract.
  135. UJetter A, uKinzig-Schippers M, uWalchner-Bonjean M, et al. Iziphumo zencindi yesidiliya kwi-pharmacokinetics ye-sildenafil. KwiKlinikhi ye-Pharmacol Ther 2002; 71: 21-9. Jonga i-abstract.
  136. UCastro N, uJung H, uMedina R, et al. Unxibelelwano phakathi kwencindi yomdiliya kunye nepraziquantel ebantwini. Iiarhente zeAntimicrob Chemother 2002; 46: 1614-6. Jonga i-abstract.
  137. Lilja JJ, Kivisto KT, Neuvonen PJ. Ixesha lesiphumo sejusi yeediliya kwi-pharmacokinetics ye-CYP3A4 substrate simvastatin. Iiklinikhi zeFarmacol Ther 2000; 68: 384-90. Jonga i-abstract.
  138. Ibailey DG, isinxibo seGK. Ukudibana kwejusi yesiqhamo-i-lovastatin. KwiKlinikhi ye-Pharmacol Ther 2000; 67: 690. Jonga i-abstract.
  139. Uno T, Ohkubo T, uSugawara K, okqhubekayo. Iziphumo zejusi yeziqhamo ze grapefruit kwisimo se-nicardipine ebantwini: ubungqina bokupheliswa kwenkqubo enkqubela phambili kwindawo yamathumbu. I-Eur J Clin Pharmacol 2000; 56: 643-9. Jonga i-abstract.
  140. I-Ho PC, i-Ghose K, i-Saville D, i-Wanwimolruk S.Impembelelo yejusi yeziqhamo kwi-pharmacokinetics kunye ne-pharmacodynamics ye-verapamil enantiomers kumavolontiya asempilweni. I-Eur J Clin Pharmacol 2000; 56: 693-8. Jonga i-abstract.
  141. UChan WK, Nguyen LT, uMiller VP, uHarris RZ. Ukungasebenzi kwe-Mechanism esekwe kwi-cytochrome yabantu i-P450 3A4 ngejusi yeziqhamo zeediliya kunye newayini ebomvu. Ubomi beSayensi 1998; 62: PL135-42. Jonga i-abstract.
  142. U-Erlund I, Meririnne E, Alfthan G, Aro A.Plasma kinetics kunye nokukhutshwa komchamo kwe-flavanones naringenin kunye ne-hesperetin ebantwini emva kokungenisa ijusi yeorenji kunye nejusi yeziqhamo. J Utyango 2001; 131: 235-41. Jonga i-abstract.
  143. Lilja JJ, Kivisto KT, Backman JT, Neuvonen PJ. Iziphumo zedosi yejusi yeziqhamo zeediliya kwisiqhamo seediliya-triazolamukunxibelelana: ukusetyenziswa okuphindiweyo kuyolula i-triazolam isiqingatha sobomi. I-Eur J Clin Pharmacol 2000; 56: 411-5. Jonga i-abstract.
  144. I-Bailey DG, i-GK yokunxiba, uMunoz C, et al. Ukuncitshiswa kwe-fexofenadine bioavailability yijusi yeziqhamo. Iiklinikhi zeFarmacol Ther 2001; 69: P21.
  145. Umnxibi GK, Bailey DG, Carruthers SG. Ukudibana kwejusi-felodipine kubantu abadala. KwiKlinikhi ye-Pharmacol Ther 2000; 68: 28-34. Jonga i-abstract.
  146. ITroisi RJ, iWillett WC, i-Weiss ST, et al. Isifundo ekujongwe ukuba senziwe kukutya kunye nesifo sombefu sabantu abadala. NdinguJ J wokuKhathalela uCrit Crit Med 1995; 151: 1401-8. Jonga i-abstract.
  147. I-Butland BK, i-Fehily AM, i-Elwood PC. Ukutya, ukusebenza kwemiphunga, kunye nokusebenza kwemiphunga kuyehla kwiqela lama-2512 aphakathi kwamadoda. Isithsaba 2000; 55: 102-8. Jonga i-abstract.
  148. USchwartz J, uWeiss ST. Ubudlelwane phakathi kokutya i-vitamin C kunye nokusebenza kwepulmonary kuVavanyo lwezeMpilo lweSizwe kunye noVavanyo lwezeMpilo (NHANES I). NdinguJ J Clin Nutriti 1994; 59: 110-4. Jonga i-abstract.
  149. Unonophelo lwe-IM, iStrachan DP, Cook DG. Iziphumo zotshintsho kusetyenziso lweziqhamo ezitsha ekusebenzeni komoya kubantu abadala baseBritane. NdinguJ J wokuKhathalela uKhathalelo nge-1998; 158: 728-33. Jonga i-abstract.
  150. Ukuqandusela GE. Isifuba, i-inhalled oxidants, kunye ne-antioxidants yokutya. NdinguJ J Nutriti 1995; 61: 625S-30S. Jonga i-abstract.
  151. UForastiere F, uPistelli R, uSestini P, et al. Ukusetyenziswa kwesiqhamo esitsha esityebileyo kwi-vitamin C kunye neempawu zokufudumeza ebantwaneni. Isithsaba 2000; 55: 283-8. Jonga i-abstract.
  152. UVon Woedtke T, uSchluter B, uPflegel P, okqhubekayo. Imiba yokusebenza kwe-antimicrobial of the grapefruit seed extract kunye nokunxulumana kwayo nezinto ezigcinayo eziqulethwe. I-Pharmazie 1999; 54: 452-6. Jonga i-abstract.
  153. U-Ionescu G, uKiehl F, uWichmann-Kunz F, et al. Unxibelelwano Ukukhutshwa kwembewu ye-citrus yomlomo kwi-atopic eczema: kwi-vitro nakwizifundo ze-vivo kwi-microflora yamathumbu. J Orthomolec Med 1990; 5: 155-7.
  154. URanzani MR, uFonseca H.Uvavanyo lwe-Mycological lokunyanga ngamandongomane anganyangekiyo. Ukongezwa kokutya Contam 1995; 12: 343-6. Jonga i-abstract.
  155. I-Calori-Domingues MA, i-Fonseca H.Uvavanyo lweLebhu yolawulo lweekhemikhali lweemveliso ze-aflatoxin kumandongomane angenagwele (Arachis hypogaea L.). Ukongezwa kokutya Contam 1995; 12: 347-50. Jonga i-abstract.
  156. USakamoto S, Sato K, Maitani T, Yamada T. [Uhlalutyo lwezinto ezongezwayo kwindalo yokutya yendalo "isicatshulwa sembewu yeediliya" yiHPLC kunye neLC / MS]. U-Eisei Shikenjo Hokoku 1996;: 38-42. Jonga i-abstract.
  157. Xiong H, Li Y, Slavik MF, Walker JT. Ukutshiza ulusu lwenkukhu ngeekhemikhali ezikhethiweyo ukunciphisa iSalmonella typhimurium. J Iprotheni yokutya 1998; 61: 272-5. Jonga i-abstract.
  158. Yena K, Iyer KR, Hayes RN, et al. Ukungasebenzi kwecytochrome P450 3A4 yi-bergamottin, icandelo lejusi yeziqhamo. IChem Res Toxicol 1998; 11: 252-9. Jonga i-abstract.
  159. ICoreg monograph. Ku: Gillis MC, Ed. Isishwankathelo samayeza kunye nezinto ezikhethekileyo (CPS). Umhla wama-34. I-Ottawa, Ontario, INGABE: Oosokhemisti baseCanada uAssn, 1999: 395.
  160. Umnxibi GK, Spence JD, Bailey DG. Iziphumo ze-Pharmacokinetic-pharmacodynamic kunye nokubaluleka kweklinikhi ye-cytochrome P450 3A4 inhibition. Kwiiklinikhi zeFarmacokinet 2000; 38: 41-57. Jonga i-abstract.
  161. UTakanaga H, Ohnishi A, Matsuo H, et al. Uhlalutyo lwe-Pharmacokinetic ye-felodipine-grapefruit ijusi yokunxibelelana esekwe kwimodeli yokuthintela i-enzyme. UBr J Clin Pharmacol 2000; 49: 49-58. Jonga i-abstract.
  162. UTakanaga H, Ohnishi A, uMurakami H, et al. Ubudlelwane phakathi kwexesha emva kokutya incindi yeziqhamo zeediliya kunye nefuthe kwi-pharmacokinetics kunye ne-pharmacodynamics ye-nisoldipine kwizifundo ezisempilweni. Iiklinikhi Pharmacol Ther 2000: 67: 201-14. Jonga i-abstract.
  163. UDamkier P, uHansen LL, uBrosen K. Iziphumo ze-diclofenac, i-disulfiram, i-itraconazole, ijusi yamagilebhisi kunye ne-erythromycin kwi-pharmacokinetics ye-quinidine. UBr J Clin Pharmacol 1999; 48: 829-38. Jonga i-abstract.
  164. van Agtmael MA, Gupta V, van der Graaf CA, van Boxtel CJ. Iziphumo zejusi yeziqhamo ze grapefruit ekunciphiseni kwexesha lokuxhomekeka kwinqanaba le-artemether plasma kwizifundo ezisempilweni. Kwiklinikhi ye-Pharmacol Ther 1999; 66: 408-14. Jonga i-abstract.
  165. van Agtmael MA, Gupta V, van der Wosten TH, okqhubekayo. Ijusi yeziqhamo zeediliya inyusa ukufumaneka kwe-artemether. I-Eur J Clin Pharmacol 1999; 55: 405-10. Jonga i-abstract.
  166. Oesterheld J, Kallepalli BR. Ijusi yamagilebhisi kunye ne-clomipramine: ukutshintsha kwemilinganiselo ye-metabolism. J Iiklinikhi zePsychopharmacol 1997; 17: 62-3.
  167. Ikhowudi yeKhompyuter yeMigaqo yeFederal. Itayitile 21. Icandelo le-182 -Iziyobisi zivunywa ngokubanzi njengezikhuselekileyo. Ifumaneka kwi: https://www.accessdata.fda.gov/script/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  168. Evans AM. Impembelelo yezinto zokutya kwimetabolism yamathumbu kunye nokuthuthwa kweziyobisi. Unyango lweziyobisi kwiTher 2000; 22: 131-6. Jonga i-abstract.
  169. UFuhr U. Unxibelelwano lweziyobisi kunye neJusi yeGrapefruit. Iziyobisi zeSaf 1998; 18: 251-72. Jonga i-abstract.
  170. ICurhan GC, iWillett WC, iSithethi FE, iStamfer MJ. Ukusetyenziswa kotywala kunye nomngcipheko wamatye ezintso kwabasetyhini. UAnn Intern Med 1998; 128: 534-40. Jonga i-abstract.
  171. I-Ameer B, i-Weintraub RA. Ukudibana kweziyobisi nejusi yeziqhamo. Iiklinikhi zeFarmacokinet 1997; 33: 103-21. Jonga i-abstract.
  172. Lilja JJ, Kivisto KT, Neuvonen PJ. Ukudibana kwejusi yesiqhamo-isimvastatin: Iziphumo ze-serum ye-simvastatin, i-simvastatin acid, kunye ne-HMG-CoA reductase inhibitors. Iiklinikhi zeFarmacol Ther 1998; 64: 477-83. Jonga i-abstract.
  173. UKupferschmidt HH, uFattinger KE, Ha HR, et al. Ijusi yamagilebhisi inyusa ukungafumaneki kwe-HIV protease inhibitor saquinavir emntwini. UBr J Clin Pharmacol 1998; 45: 355-9. Jonga i-abstract.
  174. Lilja JJ, Kivisto KT, Backman JT, okqhubekayo. Ijusi yeziqhamo ze grapefruit inyusa kakhulu i-plasma ye-buspirone. Iiklinikhi zeFarmacol Ther 1998; 64: 655-60. Jonga i-abstract.
  175. UFukuda K, Ohta T, uOshima Y, et al. I-CYP3A4 inhibitors ekhethekileyo kwijusi yeziqhamo zeediliya: i-furocoumarin dimers njengezinto zonxibelelwano. I-Pharmacogenetics 1997; 7: 391-6. Jonga i-abstract.
  176. UZhang YD, Lorenzo B, Reidenberg MM. Ukuthintela i-11 beta hydroxysteroid dehydrogenase efunyenwe kwizintso zehagu ye-guinea yi-furosemide, naringenin kunye nezinye iikhompawundi. J Steroid Biochem Mol Biol 1994; 49: 81-5. Jonga i-abstract.
  177. ULee YS, uLorenzo BJ, uKoufis T, et al. Ijusi yamagilebhisi kunye ne-flavonoids yayo inqanda i-beta-hydroxysteroid dehydrogenase eyi-11. KwiKlinikhi ye-Pharmacol Ther 1996; 59: 62-71. Jonga i-abstract.
  178. UZaidenstein R, uDishi V, uGips M, et al. Iziphumo zejusi yeziqhamo ze grapefruit kwi-pharmacokinetics ye-verapamil elawulwa ngomlomo. I-Eur J Clin Pharmacol 1998; 54: 337-40. Jonga i-abstract.
  179. Ukudibana kwesiyobisi seGrapefruit. Ifumaneka kwi: www.powernetdesign.com/grapefruit (Ifumaneka nge-26 Septemba 1999).
  180. I-Ozdemir M, uAktan Y, uBoydag BS. Ukudibana phakathi kwencindi yediliya kunye nediyazepam ebantwini. I-Eur J yeziyobisi iMetab Pharmacokinet 1998; 23: 55-9. Jonga i-abstract.
  181. Lilja JJ, Kivisto KT, Neuvonen PJ. Ijusi yamagilebhisi inyusa ukugxila kwe-serum ye-atorvastatin kwaye ayinampembelelo kwipravastatin. KwiKlinikhi ye-Pharmacol Ther 1999; 66: 118-27. Jonga i-abstract.
  182. Gross AS, Goh YD, Addison RS, et al. Impembelelo yesiselo seediliya kwi-cisapride pharmacokinetics. KwiKlinikhi ye-Pharmacol Ther 1999; 65: 395-401. Jonga i-abstract.
  183. IVaris T, Kivisto KT, Neuvonen PJ. Ijusi yamagilebhisi inokunyusa uxinzelelo lweplasma ye-methylprednisolone. I-Eur J Clin Pharmacol 2000; 56: 489-93. Jonga i-abstract.
  184. UCerda JJ, uRobbins FL, uBurgin CW, okqhubekayo. Iziphumo ze grapefruit pectin kwizigulana ezisemngciphekweni wesifo sentliziyo ngaphandle kokutshintsha ukutya okanye indlela yokuphila. KwiKlinikhi Cardiol 1988; 11: 589-94. Jonga i-abstract.
  185. Umnxibi GK, Bailey DG, Carruthers SG. Ukudibana kweJusi-felodipine kubantu abadala abasempilweni. Iiklinikhi Pharmacol Ther 1998; 65: (i-abstract PIII-63).
  186. UZaidenstein R, uAvni B, uDishi V, et al. Iziphumo zencindi yediliya kwi-pharmacokinetics ye-losartan kumavolontiya asempilweni. I-Clin Pharmacol Ther 1998; 65: (i-PI-60 engabonakaliyo).
  187. Soldner A, amaKristu u, Susanto M, et al. Ijusi yeziqhamo zeediliya yenza ukuba ukuthuthwa kweziyobisi okulamlweyo yi-P-glycoprotein. I-Pharm Res 1999; 16: 478-85. Jonga i-abstract.
  188. I-Bailey DG, i-GK yokunxiba, i-Kreeft JH, et al. Ukudibana kwejusi-felodipine: Iziphumo zamacandelo kunye nokukhutshwa kwesiqhamo esingasetyenziswanga. Iiklinikhi Pharmacol Ther 2000; 67: 107 (abstract PI-71).
  189. IVeronese M, uBurke J, uDorval E, et al. Ijusi yamagilebhisi (GFJ) inqanda i-hepatic kunye ne-intestinal ye-CYP3A4 i-dose-exhomekeke. Iiklinikhi Pharmacol Ther 2000; 67: 151 (abstract PIII-37).
  190. I-Offman EM, iFreeman DJ, isinxibo seGK, et al. Ukudibana kweCisapride kunye nejusi yeziqhamo kunye newayini ebomvu. Iklinikhi ye-Pharmacol Ther 2000; 67: 110 (i-PI-83 engafakwanga).
  191. URobbins RC, uMartin FG, uRoe JM. Ukungeniswa kweziqhamo zeediliya kunciphisa iihematocrits eziphakamileyo kwizifundo zabantu. I-Int J Vitam Nutr Res 1988; 58: 414-7. Jonga i-abstract.
  192. URau SE, uBend JR, uArnold MO, et al. Ukudibana kwejusi-terfenadine ukusebenzisana kwethamo elinye: ubukhulu, indlela yokusebenza, kunye nokubaluleka. KwiKlinikhi ye-Pharmacol Ther 1997 61: 401-9. Jonga i-abstract.
  193. Ibailey DG, uArnold JM, Strong HA, et al. Iziphumo zencindi yediliya kunye ne-naringin kwi-nisoldipine pharmacokinetics. KwiKlinikhi ye-Pharmacol Ther 1993; 54: 589-94. Jonga i-abstract.
  194. Ibailey DG, Spence JD, Munoz C, uArnold JM. Ukudibana kweencindi zesitrasi kunye nefelodipine kunye nifedipine. ILancet 1991; 337: 268-9. Jonga i-abstract.
  195. UKantola T, Kivisto KT, Neuvonen PJ, okqhubekayo. Ijusi yamagilebhisi inyusa kakhulu ukugxila kwe-serum ye-lovastatin kunye ne-lovastatin acid. Iiklinikhi Pharmacol Ther 1998 63: 397-402. Jonga i-abstract.
  196. I-Schubert W, i-Cullberg G, i-Edgar B, i-Hedner T. Ukuthintela i-17 beta-estradiol metabolism yijusi yeziqhamo zeediliya kubafazi abakhethiweyo. IMaturitas 1994; 20: 155-63. Jonga i-abstract.
  197. UWeber A, uJager R, uBorner A, et al. Ngaba ijusi yeziqhamo zediliya inefuthe kwi-ethinylestradiol bioavailability? Ukuthintela ukukhulelwa 1996; 53: 41-7. Jonga i-abstract.
  198. IGarg SK, Kumar N, Bhargava VK, Prabhakar SK. Iziphumo zencindi yediliya kwi-carbamazepine bioavailability kwizigulana ezinesathuthwane. Iiklinikhi zeFarmacol Ther 1998; 64: 286-8. Jonga i-abstract.
  199. UJosefsson M, uZackrisson AL, uAhlner J. Iziphumo zejusi yeziqhamo kwi-pharmacokinetics ye-amlodipine kumavolontiya asempilweni. I-Eur J Clin Pharmacol 1996; 51: 189-93. Jonga i-abstract.
  200. UIoannides-Demos LL, uChristophidis N, et al. Ukunyanzelwa kokunxibelelana kweklinikhi phakathi kwejusi yamagilebhisi kunye necyclosporine kunye nokugxila kwimetabolite kwizigulana ezinezifo ezizimele. J Rheumatol 1997; 24: 49-54. Jonga i-abstract.
  201. I-Agri Res Svc: Ugcino lukaDkt.Duke's phytochemical kunye ethnobotanical database. www.ars-grin.gov/duke (Ifumaneka nge-3 Novemba 1999).
  202. IPenzak SR, Gubbins PO, Gurley BJ, et al. Ijusi yeziqhamo zeediliya inciphisa ukufumaneka kwenkqubo yee-capsules ze-itraconazole kumavolontiya asempilweni. Unyango lweziyobisi kwiTher 1999; 21: 304-9. Jonga i-abstract.
  203. Ukungqinisisa uBrinker F.Herb kunye nokuNxibelelana kweziyobisi. Ngomhla wesi-2. Isanti, OKANYE: Ushicilelo lwezoNyango lweEclectic, 1998.
Ukuhlaziywa okokugqibela-03/24/2020

Inomdla Namhlanje

Unganyanga njani okanye ususe iiTatoo Scars
Zempilo

Unganyanga njani okanye ususe iiTatoo Scars

Yintoni uphawu lwe tattoo?Umvambo weTattoo yimeko enezizathu ezininzi. Abanye abantu bafumana amanxeba etattoo kwiitattoo zabo zokuqala ngenxa yeengxaki ezivela ngexe ha lokwenza umvambo kunye nokuph...
Izibonelelo kunye neziphumo ebezingalindelekanga zeSalicylic Acid Peels
Zempilo

Izibonelelo kunye neziphumo ebezingalindelekanga zeSalicylic Acid Peels

ibandakanya iimveli o e icinga ukuba ziluncedo kubafundi bethu. Ukuba uthenga amakhonkco kweli phepha, inokufumana ikhomi hini encinci. Nant i inkqubo yethu.I- alicylic acid peel ayi iyiyo indlela en...