Umbhali: William Ramirez
Umhla Wokudalwa: 15 Eyomsintsi 2021
Hlaziya Umhla: 11 Eyomsintsi 2024
Anonim
Vitamin K and hemostasis
Ividiyo: Vitamin K and hemostasis

Umxholo

I-Vitamin K yivithamini efumaneka kwimifuno eluhlaza, i-broccoli kunye ne-Brussels. Igama uvithamini K livela kwigama lesiJamani "Koagulationsvitamin."

Iindidi ezininzi zevithamini K zisetyenziswa njengeyeza kwihlabathi liphela. I-Vitamin K1 (phytonadione) kunye ne-vitamin K2 (menaquinone) ziyafumaneka eMntla Melika. I-Vitamin K1 ngokubanzi yeyona fomu ikhethwayo yevithamin K kuba ayinetyhefu encinci kwaye isebenza ngokukhawuleza kwiimeko ezithile.

I-Vitamin K ixhaphake kakhulu xa kusenziwa iingxaki zokunqanda igazi okanye ukuguqula iimpembelelo ze-warfarin.Isetyenziselwa ezinye iimeko ezininzi, kodwa abukho ubungqina obuchanekileyo benzululwazi obuxhasa uninzi lwezi zinto zisetyenziswayo.

Amayeza endalo aVimba weDatha Ukusebenza kwexabiso ngokusekwe kubungqina besayensi ngokwala manqanaba alandelayo: Ukusebenza, ukusebenza ngokukuko, okunokwenzeka ukuba kusebenze, okungenzeka kungasebenzi, kunokwenzeka ukungasebenzi, ukungasebenzi, kunye nobungqina obungonelanga bokulinganisa.

Ukulinganiswa kokusebenza kwe IVITAMIN K zezi zilandelayo:


Ukusebenza ...

  • Iingxaki zokopha kwiintsana ezisanda kuzalwa ezinamanqanaba asezantsi evithamini K (isifo sokopha). Ukunika ivithamin K1 ngomlomo okanye njengefoto kwisihlunu kunceda ukunqanda ukopha kwiingxaki kwiintsana. Ukudubula kubonakala kusebenza kakhulu.
  • Amanqanaba asezantsi eproteni yokuvala igazi prothrombin (hypoprothrombinemia). Ukuthatha i-vitamin K1 ngomlomo okanye njenge-injection emthanjeni kunokuthintela nokunyanga iingxaki zokuphuma kwegazi kubantu abanamanqanaba aphantsi e-prothrombin ngenxa yokusebenzisa amayeza athile.
  • Isifo esingaqhelekanga, esivela kwilifa (ukopha ku-vitamin K) okanye i-VKCFD). Ukuthatha i-vitamin K ngomlomo okanye njenge-injection kwi-vein kunokunceda ukukhusela ukuphuma kwegazi kubantu abane-VKCFD.
  • Ukuguqula ukubuyela egazini kwiziphumo ze-warfarin. Ukuthatha ivithamin K1 ngomlomo okanye njengokufaka inaliti emthanjeni kunokubuyisa ukuthoba igazi okuninzi okubangelwa yi-warfarin. Nangona kunjalo, ukutofa i-vitamin K1 phantsi kolusu kubonakala kungasebenzi. Ukuthatha i-vitamin K kunye ne-warfarin kubonakala ngathi kunceda ukuzinzisa ixesha lokunqanda igazi kubantu abathatha i-warfarin. Isebenza kakuhle kubantu abanamanqanaba asezantsi e-vitamin K.

Inokwenzeka ukuba isebenze ...

  • Amathambo abuthathaka kunye nophuko (i-osteoporosis). Ukuthatha uhlobo oluthile lwevithamini K2 kubonakala ngathi kuphucula amandla amathambo kunye nokunciphisa umngcipheko wokwaphuka kuninzi lwabasetyhini abadala abanamathambo abuthathaka. Kodwa akubonakali kunceda abafazi abadala abasenamathambo omeleleyo. Ukuthatha ivithamin K1 kubonakala kukonyusa amandla ethambo kwaye kunokuthintela ukwaphuka kwabasetyhini abadala. Kodwa isenokungasebenzi nakumadoda amadala. I-Vitamin K1 ayibonakali iphucula amandla ethambo kwabasetyhini abangakhange baye exesheni okanye kubantu abanesifo seCrohn.

Kusenokwenzeka ukuba ayisebenzi ...

  • Ukopha ngaphakathi okanye kwindawo ezijikeleze ulwelo (ii-ventricles) zobuchopho (intraventricular hemorrhage). Ukunika ivithamin K kwabasetyhini abasemngciphekweni wokuzalwa ngaphambi kwexesha kakhulu akubonakali ngathi kuthintela ukopha kwingqondo yeentsana ezizelwe ngaphambi kwexesha. Kananjalo kubonakala ngathi awunciphisi ubungozi benzakala yemithambo-luvo ebangelwa zezi gazi.

Akukho bungqina baneleyo bokulinganisa ukusebenza ...

  • Ukusebenza kwezemidlalo. Uphando lwakwangoko lubonisa ukuba ukuthatha i-vitamin K2 ngomlomo kunokuphucula ukusebenza ngokuzilolonga ngokwandisa umsebenzi wentliziyo.
  • Ukuphazamiseka kwegazi okunciphisa amanqanaba eprotini egazini elibizwa ngokuba yihemoglobin (beta-thalassemia). Uphando lwakwangoko lubonisa ukuba ukuthatha i-vitamin K2 ngomlomo kunye ne-calcium kunye no-vitamin D kunokuphucula ubunzima bamathambo kubantwana abanesifo segazi.
  • Umhlaza webele. Uphando lubonisa ukuba ukutya okuphezulu kwe-vitamin K2 kudibene nomngcipheko omncinci wokuba nomhlaza wamabele.
  • Umhlaza. Olunye uphando luye lwadibanisa ukutya okuphezulu kwe-vitamin K2, kodwa kungekhona i-vitamin K1, kunye nomngcipheko omncinci wokufa ngenxa yomhlaza. Kodwa olunye uphando luye lwadibanisa ukutya okuphezulu kwe-vitamin K1, kodwa kungekhona i-vitamin K2, kunye nomngcipheko wokunciphisa ukufa komhlaza.
  • Iimpawu. Olunye uphando luye lwadibanisa ukutya okuphezulu kwe-vitamin K2 kunye nomngcipheko omncinci wokufumana i-cataract.
  • Umhlaza wekolon, umhlaza we-rectal. Uphando lwakwangoko lubonisa ukuba ukutya okuninzi okutya i-vitamin K akuhambelani nomngcipheko omncinci womhlaza wekholoni kunye ne-rectum.
  • Isifo sentliziyo. Uninzi lophando lubonisa ukuba ukutya okuphezulu kwe-vitamin K1 kunye ne-K2 kudibene nomngcipheko omncinci wesifo sentliziyo. Kodwa ukutya okuphezulu kokutya i-vitamin K1 akubonakali kunciphisa umngcipheko wokufa sisifo sentliziyo ngokubanzi.
  • Icystic fibrosis. Abantu abane-cystic fibrosis banamanqanaba asezantsi e-vitamin K ngenxa yeengxaki zokugaya amafutha. Ukuthatha ivithamin K kunyusa amanqanaba e-vitamin K. Kodwa akucaci ukuba kuthintela iingxaki ekunqandeni igazi kunye nokukhula kwethambo kwaba bantu.
  • Uxinzelelo. Uphando lwakwangoko lufumanise ukuba ukutya okuphezulu kwe-vitamin K ekutyeni kunxulunyaniswa nomngcipheko ophantsi woxinzelelo. Kodwa akukho phando malunga nokuba ukuthatha izongezo ze vithamin K kunokuwunciphisa umngcipheko woxinzelelo.
  • Seswekile. Uphando lwakwangoko lubonisa ukuba ukuthatha i-multivitamin eqiniswe nge-vitamin K1 akuwunciphisi umngcipheko wokuba nesifo seswekile xa kuthelekiswa nokuthatha imultivitamin yesiqhelo.
  • Irhashalala elifana namabala elibangelwa ziziyobisi ezithile zomhlaza. Abantu abanikwa uhlobo oluthile lwamayeza e-anticancer bahlala bekhula ulusu. Uphando lwakwangoko lubonisa ukuba ukufaka ukhilimu oqukethe ivithamin K1 kunceda ukuthintela ukurhawuzelela kolusu kubantu abanikwa olu hlobo lwamayeza. Kodwa olunye uphando lubonisa ukuba ukusebenzisa ioyile enevithamini K akuphuculi oku kurhwaphiliza kwabantu esele bekhulile.
  • Cholesterol ephezulu. Kukho ubungqina bokuqala bokuba i-vitamin K2 inokunciphisa i-cholesterol kubantu abakwi-dialysis ngamanqanaba aphezulu e-cholesterol.
  • Umhlaza wesibindi. Ukuthatha ivithamini K2 akubonakali ngathi kuthintela ukuphindaphinda komhlaza wesibindi. Kodwa olunye uphando lwakwangoko lubonisa ukuba ukuthatha i-vitamin K2 kunciphisa umngcipheko womhlaza wesibindi kubantu abane-cirrhosis yesibindi.
  • Isifo sesibindi. Ukujova i-vitamin K kwisihlunu kunxulunyaniswe nomngcipheko omncinci wokufa kwabantu abanesibindi.
  • Umhlaza wemiphunga. Uphando lwakwangoko lubonisa ukuba ukutya kakhulu i-vitamin K2 ekutyeni kunxulunyaniswa nomngcipheko omncinci womhlaza wemiphunga kunye nokufa okunxulumene nomhlaza wemiphunga. Ukutya i-vitamin K1 akubonakali ngathi kunxulunyaniswa nomngcipheko omncinci wezi ziganeko.
  • Multiple sclerosis (MS). I-Interferon liyeza elinceda abantu abane-MS. Eli yeza kuhlala kubangela irhashalala kunye nokutsha kolusu. Uphando lwakwangoko lubonisa ukuba ukusebenzisa i-vitamin K cream ngokuthozama kunciphisa irhashalala kunye nokutsha kwabantu abaphathwe nge-interferon.
  • Ukufa nangasiphi na isizathu. Ukutya okuncinci kwe-vitamin K kunokunxulunyaniswa nomngcipheko ophezulu wokufa kubantu abadala abasempilweni.
  • Umhlaza wedlala lobudoda. Uphando lwakwangoko lufumanise ukuba ukutya okuphezulu kwe-vitamin K2, kodwa hayi ivithamin K1, kunxulunyaniswa nomngcipheko omncinci womhlaza webele.
  • Isifo samathambo (RA). Uphando lwakwangoko lubonisa ukuba ukuthatha i-vitamin K2 kunye namayeza e-arthritis kunciphisa amanqaku okudumba okungcono kunokuthatha amayeza e-arthritis wedwa. Kodwa ukuthatha i-vitamin K1 kubonakala ngathi kunciphisa iimpawu ze-RA.
  • Ukubetha. Uphando lwabemi lufumene ukuba ukutya okutyayo i-vitamin K1 akunxulunyaniswa nomngcipheko omncinci wokuhlaselwa sisifo.
  • Imivumbo.
  • Ukutsha.
  • Izibazi.
  • Imithambo yesigcawu.
  • Yolula amanqaku.
  • Ukudumba.
  • Ezinye iimeko.
Ubungqina obungakumbi buyafuneka ukukala i-vitamin K kwezi zinto zisetyenziswayo.

I-Vitamin K yivithamini ebalulekileyo efunekayo emzimbeni ekunqandeni igazi, ekwakheni amathambo, kunye nezinye iinkqubo ezibalulekileyo.

Xa kuthathwa ngomlomo: Ezi ntlobo zimbini zevithamini K (ivithamin K1 kunye nevithamini K2) ZIKHUSELEKILE KAKHULU kuninzi lwabantu xa zithathwe ngokufanelekileyo. I-Vitamin K1 10 mg yonke imihla kunye nevithamini K2 45 mg yonke imihla zisetyenziswe ngokukhuselekileyo ukuya kuthi ga kwiminyaka emi-2. Uninzi lwabantu alunazo naziphi na iziphumo ebezingalindelekanga xa uthatha ivithamin K kwisixa esinconyelwayo suku ngalunye. Kodwa abanye abantu banokuba nesisu okanye isisu esihambisayo.

Xa isetyenziswa eluswini: Vitamin K1 yi UKHUSELEKO OLUNOKWENZEKA kubantu abaninzi xa isetyenziswa njengokhilimu oqukethe i-0.1% ye-vitamin K1.

Xa unikwe ngu-IV: Ezi ntlobo zimbini zevithamini K (ivithamin K1 kunye nevithamini K2) zezi NGOKUKHUSELEKILEYO kubantu abaninzi xa betofelwe emthanjeni ngokufanelekileyo.

Amanyathelo okhuseleko kunye nezilumkiso:

Ukukhulelwa kunye nokuncancisa: Xa kuthathwa isixa esinconywayo ngosuku ngalunye, uvithamini K ngu NGOKUKHUSELEKILEYO kubafazi abakhulelweyo nabancancisayo. Sukusebenzisa izixa eziphezulu ngaphandle kwengcebiso yengcali yezempilo.

AbantwanaUhlobo lwevithamini K eyaziwa ngokuba yi-vitamin K1 NGOKUKHUSELEKILEYO yabantwana xa bethathwe ngomlomo okanye betofelwe emzimbeni ngokufanelekileyo.

Isifo sezintso: I-vitamin K eninzi inokuba yingozi xa ufumana unyango lwe-dialysis ngenxa yesifo sezintso.

Isifo sesibindiI-Vitamin K ayisebenzi ekunyangeni iingxaki zokujiyiswa okubangelwa sisifo esibi sesibindi. Ngapha koko, iidosi eziphezulu zevithamini K zinokuzenza iingxaki zokuqina ziba mandundu kwaba bantu.

Ukunciphisa ukugcinwa kwe-bileAbantu abanokwehla kwe-bile secretion abathatha i-vitamin K kusenokufuneka bathathe iityuwa ezongezelelekileyo ze-bile kunye ne-vitamin K yokuqinisekisa ukufakwa kwe-vitamin K.

Mkhulu
Sukuyithatha le indibaniselwano.
IWarfarin (Coumadin)
I-Vitamin K isetyenziswa ngumzimba ukunceda igazi. IWarfarin (Coumadin) isetyenziselwa ukucothisa ukujiya kwegazi. Ngokunceda i-clot yegazi, i-vitamin K inokunciphisa ukusebenza kwe-warfarin. Qiniseka ukuba igazi lakho lihlolwe rhoqo. Umthamo we-warfarin yakho unokufuna ukuba utshintshwe.
ICoenzyme Q10
I-Coenzyme Q10 ifana ne-vitamin K ngokwemichiza kwaye, njengevithamini K, inokukhuthaza ukujiya kwegazi. Ukusebenzisa ezi mveliso zimbini kunye kunokukhuthaza ukujija kwegazi ngaphezulu kokusebenzisa enye. Olu dibana lunokuba yingxaki kubantu abathatha i-warfarin ukuze bacothe ukujiya kwegazi. I-Coenzyme Q10 kunye ne-vitamin K inokuphazamisa iimpembelelo ze-warfarin kwaye inokuvumela igazi ukuba livale.
Itiratricol
Kukho inkxalabo yokuba i-tiratricol inokuphazamisa indima ye-vitamin K ekunqandeni igazi.
Vitamin A
Kwizilwanyana, iidosi eziphezulu zevithamini A ziphazamisana namandla evithamini K okuvala igazi. Kodwa akwaziwa ukuba oku kuyenzeka nasebantwini.
Vitamin E
Amanani aphezulu evithamini E (umz.ngaphezulu kweeyunithi ezingama-800 / ngosuku) angenza ukuba ivithamin K ingasebenzi kakuhle ekunqandeni igazi. Kubantu abathatha i-warfarin ukugcina igazi labo lingadibani, okanye kubantu abane-vitamin K ephantsi, amanani aphezulu e-vitamin E anokunyusa umngcipheko wokopha.
Amafutha kunye nokutya okunamafutha
Ukutya ukutya okuqukethe ibhotolo okanye amanye amafutha okutya ngokudibeneyo nokutya okuqulathe ivithamin K, njengespinatshi, kubonakala ngathi kwandisa ukufakwa kwe-vitamin K.
La machiza alandelayo afundwe kuphando lwezesayensi:

ABADALA

NGOMLOMO:
  • Amathambo abuthathaka kunye nophuko (i-osteoporosis)Ifom ye-MK-4 ye-vitamin K2 ithathiwe ngeedosi ezingama-45 mg yonke imihla. Kwakhona, ivithamini K1 ithathiwe ngeedosi ze-1-10 mg yonke imihla.
  • Ngesifo esingaqhelekanga, sokuphuma kwegazi (i-vitamin K-exhomekeke kwizinto ezinqabileyo okanye i-VKCFD): 10 mg wevithamini K uthathwe amaxesha ama-2-3 ngeveki.
  • Ukuguqula ukuhla kwegazi ngenxa ye-warfarin: Idosi enye ye-1-5 mg ye-vitamin K1 isetyenziselwa ukubuyisa iziphumo zokuthatha i-warfarin eninzi. Idosi echanekileyo efunekayo igqitywa luvavanyo lweelebhu olubizwa ngokuba yi-INR. Imilinganiselo yemihla ngemihla ye-100-200 micrograms ye-vitamin K isetyenziselwe abantu abathatha i-warfarin yexesha elide abane-clotting yegazi engazinzanga.
NGENALITHI:
  • Ngesifo esingaqhelekanga, sokuphuma kwegazi (i-vitamin K-exhomekeke kwizinto ezinqabileyo okanye i-VKCFD)I-10 mg ye-vitamin K itofelwe emthanjeni. Kukangaphi ezi zinaliti zinikezelwa kumiselwe kuvavanyo lweelebhu olubizwa ngokuba yi-INR.
  • Ukuguqula ukuhla kwegazi ngenxa ye-warfarinKusetyenziswa idosi enye ye-0.5-3 mg ye-vitamin K1. Idosi echanekileyo efunekayo igqitywa luvavanyo lweelebhu olubizwa ngokuba yi-INR.
ABANTWANA

NGOMLOMO:
  • Ngeengxaki zokopha kwiintsana ezinamanqanaba asezantsi evithamini K (isifo sokopha)I-1-2 mg ye-vitamin K1 inikwe iidosi ezintathu ngaphezulu kweeveki ezisi-8. Kusetyenziswe idosi enye ene-1 mg ye-vitamin K1, 5 mg ye-vitamin K2, okanye i-1-2 mg ye-vitamin K3.
NGENALITHI:
  • Ngeengxaki zokopha kwiintsana ezinamanqanaba asezantsi evithamini K (isifo sokopha)I-1 mg ye-vitamin K1 inikwe njengepuhlulo kwimisipha.
Akukho lwazi lwaneleyo lwenzululwazi lokumisela izibonelelo zokutya ezicetyiswayo (RDAs) zevithamin K, ngenxa yoko iingcebiso zemihla ngemihla ezaneleyo (AI) zisetyenziswa endaweni yoko: Ii-AI zezi: iintsana iinyanga ezi-0-6, i-2 mcg; Iintsana iinyanga ezi-7-12, 2.5 mcg; abantwana 1-3 iminyaka, 30 mcg; abantwana iminyaka 4-8, 55 mcg; abantwana iminyaka 9-13, 60 mcg; abakwishumi elivisayo abakwiminyaka eyi-14-18 (kubandakanya abo bakhulelweyo okanye abancancisayo), i-75 mcg; ngaphezu kweminyaka eli-19, 120 mcg; abasetyhini abangaphezulu kweminyaka eli-19 (kubandakanya abo bakhulelweyo kunye nabanyisayo), i-90 mcg.

I-2-methyl-1,4-naphthoquinone, 2-methyl-3-phytyl-1,4-naphthoquinone, 4-Amino-2-Methyl-1-Naphthol, Vitamin-Soluble Vitamin, Menadiol, Menadiol Acetate, Menadiol Diacetate, Menadiol Isodium Diphosphate, Menadiol Sodium Phosphate, Menadiolum Solubile Methynaphthohydroquinone, Menadione, Ménadione, Menadione Sodium Bisulfite, Menaquinone, Ménaquinone, Menatetrenone, Menatétrenone, Phytonadione, Methylphytyl Naphtylosylone, Phylonone, .

Ukuze ufunde okungakumbi malunga nokubhalwa kweli nqaku, nceda ubone Amayeza endalo aVimba weDatha indlela yokusebenza.


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  19. ILanzillo R, Moccia M, Carotenuto A, Vacchiano V, Satelliti B, Panetta V, Brescia Morra V. I-Vitamin K cream inciphisa ukusabela kwindawo yenaliti kwizigulana ezinokuphinda zibuyise-sclerosis ezininzi ezanyangwa nge-subcutaneous interferon beta -VIKING yokufunda. Iscler Scler. Ngo-2015; 21: 1215-6. Jonga i-abstract.
  20. UJuanola-Falgarona M, Salas-Salvadó J, Martínez-González Mz, Corella D, Estruch R, Ros E, Fitó M, Arós F, Gómez-Gracia E, Fiol M, Lapetra J, Basora J, Lamuela-Raventós RM, Serra. -Majem L, Pintó X, Muñoz MÁ, Ruiz-Gutiérrez V, Fernández-Ballart J, Bulló M. Ukutya ukutya kwe-vitamin K kudibene nomngcipheko wokufa. J Isondlo. Ngo-2014; 144: 743-50. Jonga i-abstract.
  21. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, fan SW. Ngaba ivithamin K2 idlala indima kuthintelo kunye nonyango lwe-osteoporosis yabasetyhini abasemva kwemini: uhlalutyo lweemeta zezilingo ezilawulwa ngokungahleliwe. Osteoporos Int. Ngo-2015; 26: 1175-86. Jonga i-abstract.
  22. UCaluwe R, uVandecasteele S, uVan Vlem B, uVermeer C, uDe Vriese AS. Ukongezwa kweVitamin K2 kwizigulana ze-hemodialysis: isifundo sokufumana idosi ngokungahleliwe. Ukufakelwa koNxibelelwano ngeNephrol. Ngo-2014; 29: 1385-90. Jonga i-abstract.
  23. U-Abdel-Rahman MS, Alkady EA, Ahmed S. Menaquinone-7 njengenyango yamayeza kunyango lwe-rheumatoid arthritis: Isifundo sonyango. I-Eur J Pharmacol. Ngo-2015; 761: 273-8. Jonga i-abstract.
  24. I-Dennis VC, iRipley TL, i-Planas LG, kunye ne-Beach P.I-vitamin K yokutya kwizigulana ze-anticoagulation yomlomo: iindlela zonyango kunye nolwazi kuseto lwangaphandle. J Pharm Technol 2008; 24: 69-76.
  25. UPathak A, uHamm CR, u-Eyal FG, uWalter K, uRijhsinghani A, kunye noBohlman M.Ulawulo lwevithamini K yoomama yolawulo lokuthintela ukopha ngaphakathi kwiintsana. Uphando lwabantwana 1990; 27: 219A.
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  28. I-Greer, i-FR, iMarshall, i-SP, i-Severson, i-RR, i-Smith, i-DA, i-Shearer, i-MJ, i-Pace, i-DG, kunye ne-Joubert, i-PHUlungiselelo olutsha lwe-micellar yokulungiselela i-vitamin K prophylaxis yomlomo: ukuthelekiswa okungahleliwe kunye nokuqulunqwa kwe-intramuscular kwiintsana ezondla . IArch. Umntwana 1998; 79: 300-305. Jonga i-abstract.
  29. Wentzien, T.H, O'Reilly, R. A., kunye noKearns, P. J.Uvavanyo lokulindela ukubuyela umva kwe-anticoagulant nge-vitamin K1 yomlomo ngelixa uqhubeka nonyango lwe-warfarin lungatshintshanga. Isifuba 1998; 114: 1546-1550. Jonga i-abstract.
  30. UDuong, T. M., Plowman, B. K., Morreale, A. P., noJanetzky, K. Ukubuyela umva kunye nokuhlalutya okukhoyo kunyango lwezigulana ezingaphaya kwamandla. I-Pharmacotherapy 1998; 18: 1264-1270. Jonga i-abstract.
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  32. Ngokukodwa, M.A, Donovan, D., Harrison, L., McGinnis, J., kunye noGinsberg, J. Idosi ephantsi yomlomo wevithamini K ngokuthembekileyo ibuyisela ngaphezulu i-anticoagulation ngenxa ye-warfarin. Ukuhluza. Ngo-1998; 79: 1116-1118. Jonga i-abstract.
  33. I-Lousberg, T. R., Witt, D. M., Beall, D. G., Carter, B. L., kunye neMalone, D. C. Uvavanyo lwe-anticoagulation egqithileyo kwimodeli yolondolozo lwempilo yeqela. IArch Intern.Iphakathi. 3-9-1998; 158: 528-534. Jonga i-abstract.
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  36. Beker, L.T, Ahrens, R. A., Fink, R. J., O'Brien, M. E., Davidson, K. W., Sokoll, L. J., noSadowski, J. A. Iziphumo zevithamin K1 yokuncedisa kwisikhundla sevithamini K kwizigulana ze-cystic fibrosis. J. Isigulana seGastroenterol. Ngo-1997; 24: 512-517. Jonga i-abstract.
  37. Bakhshi, S., Deorari, A. K., Roy, S., Paul, V. K., kunye no Singh, M. Uthintelo lwe-subclinical vitamin K ukusilela ngokusekwe kumanqanaba e-PIVKA-II: ngomlomo xa kuthelekiswa nendlela ye-intramuscular. Isilwanyana saseIndiya. Ngo-1996; 33: 1040-1043. Jonga i-abstract.
  38. UMakris, M., Greaves, M., Phillips, WS, Kitchen, S., Rosendaal, FR, kunye no-Preston, EF Emergency oral anticoagulant reversal: ukusebenza ngokuhambelana kokunyanzeliswa kweplasma efriziwe engumkhenkce kunye ne-clotting factor kugxila kulungiso lwe-coagulopathy . Ukuhluza. Ngo-1997; 77: 477-480. Jonga i-abstract.
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  40. IGijsbers, B. L., Jie, K. S., kunye neVermeer, C. Iziphumo zokwenziwa kokutya kwi-vitamin K yokufakwa kumavolontiya abantu. UBr. J. Nutrr. Ngo-1996; 76: 223-229. Jonga i-abstract.
  41. Thijssen, H. H. kunye noDrittij-Reijnders, M. J. Vitamin K ubume kwizicubu zomntu: ukuqokelelwa kwezicwili ezithile ze-phylloquinone kunye ne-menaquinone-4. UBr. J. Nutrr. Ngo-1996; 75: 121-127. Jonga i-abstract.
  42. U-White, R. H., McKittrick, T., Takakuwa, J., Callahan, C., McDonell, M., no-Fihn, S. Ulawulo kunye nokuxela ukopha okusongela ubomi ngexesha lonyango lwe-warfarin. I-Consortium yeSizwe yeeKlinikhi zeAnticoagulation. IArch Ingaphakathi. 6-10-1996; 156: 1197-1201. Jonga i-abstract.
  43. USharma, R. K., Marwaha, N., Kumar, P., kunye noNarang, A. Iziphumo zamanzi omlomo anyibilikisa ivithamin K kumanqanaba e-PIVKA-II kwiintsana. Isilwanyana saseIndiya. 1995; 32: 863-867. Jonga i-abstract.
  44. Brousson, M. A. kunye noKlein, M. C. Iimpikiswano ezijikeleze ulawulo lwevithamini K kwiintsana: uphononongo. I-CMAJ. 2-1-1996; 154: 307-315. Jonga i-abstract.
  45. UCornelissen, E. A., Kollee, L. A., van Lith, T. G., Motohara, K., noMonnens, L. A. Ukuvavanywa kwedosi yemihla ngemihla ye-25 micrograms vitamin K1 ukunqanda ukusilela kwe-vitamin K kwiintsana ezincancisayo. J. Isigulana seGastroenterol. Ngo-1993; 16: 301-305. Jonga i-abstract.
  46. I-Hogenbirk, K., Peters, M., Bouman, P., Sturk, A., kunye neBuller, HA Iziphumo zefomula xa kuthelekiswa nokuncancisa kunye nokunyusa ivithamin K1 kumanqanaba ajikelezayo e-vitamin K1 kunye neevithamini K iintsana. I-Eur. J. Isigulana. Ngo-1993; 152: 72-74. Jonga i-abstract.
  47. UCornelissen, E. A., Kollee, L. A., De Abreu, R. A., Motohara, K., noMonnens, L. A. Uthintelo lokusilela kwe vithamin K ebusaneni ngokulawulwa kweveki ye vithamini K. Acta Paediatr. Ngo-1993; 82: 656-659. Jonga i-abstract.
  48. UKlebanoff, M. A., Funda, J. S., Mills, J. L., kunye no-Shiono, P. H. Umngcipheko wesifo somhlaza wabantwana emva kokuvezwa kwe-vithamini K. N. Eng. 9-23-1993; 329: 905-908. Jonga i-abstract.
  49. UDickson, R. C., Stubbs, T. M., kunye noLazarchick, J. Unyango lwe-Vitamin K yonyango lokuzalwa kosana olunesisindo esiphantsi. Ndingu. J. Obstet. Gynecol. Ngo-1994; 170 (1 iPt 1): 85-89. Jonga i-abstract.
  50. UPengo, V., Banzato, A., Garelli, E., Zasso, A., kunye noBiasiolo, A.Ukuguqulwa kwesiphumo esigqithisileyo se-anticoagulation yesiqhelo: idosi yomlomo ephantsi ye-phytonadione (ivithamin K1) xa kuthelekiswa nokupheliswa kwe-warfarin. Igazi Coagul. I-fibrinolysis 1993; 4: 739-741. Jonga i-abstract.
  51. Thorp, JA, Parriott, J., Ferrette-Smith, D., Meyer, BA, Cohen, GR, noJohnson, J. Antepartum uvithamini K kunye ne-phenobarbital yokuthintela ukopha ngaphakathi kwentsana ngaphambi kwexesha. Uvavanyo olulawulwa yi-placebo. Isibambiso. Ngo-1994; 83: 70-76. Jonga i-abstract.
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  53. I-Taberner, D., Thomson, J. M., kunye noPoller, L. Thelekisa i-prothrombin ye-concentrate kunye ne-vitamin K1 ekubuyiseleni i-anticoagulant yomlomo. Umtshini. 7-10-1976; 2: 83-85. Jonga i-abstract.
  54. IGlover, uJ. Kunye noMorrill, G. B. Unyango olugcinayo lwezigulana ezingaphaya kwamandla. Isifuba 1995; 108: 987-990. Jonga i-abstract.
  55. UJie, K. S., Bots, M. L., Vermeer, C., Witteman, J. C., kunye noGrobbee, D. E. Vitamin K kunye namanqanaba e-osteocalcin kwabasetyhini abane-aortic atherosclerosis: isifundo esisekwe kubemi. I-atherosclerosis 1995; 116: 117-123. Jonga i-abstract.
  56. I-Sutherland, i-J., I-Glueck, i-H., Kunye no-Gleser, i-G. Ukuncancisa ibele njengento eyimfuneko kwi-pathogenesis. NdinguJ. Dis. Umntwana 1967; 113: 524-533. Jonga i-abstract.
  57. UMotohara, K., Endo, F., kunye noMatsuda, I. Ukusilela kweVitamin K kwiintsana ezincancisayo kwinyanga enye ubudala. J. Isigulana seGastroenterol. Ngo-1986; 5: 931-933. Jonga i-abstract.
  58. I-Pomerance, J. J., Teal, J. G., Gogolok, J. F., Brown, S., kunye noStewart, M. E. Maternally ilawulwa ngokwasemzimbeni i-vitamin K1: ifuthe lomsebenzi we-neonatal prothrombin, ixesha le-thromboplastin, kunye ne-intraventricular hemorrhage. Isibambiso. Ngowe-1987; 70: 235-241. Jonga i-abstract.
  59. U-O'Connor, M. E. noAdieiego, uJ. E., Jr. Ukusetyenziswa kwe-vitamin K1 yomlomo ukukhusela isifo sokopha kosana olusandul 'ukuzalwa. J. Isigulana. Ngo-1986; 108: 616-619. Jonga i-abstract.
  60. UMorales, W. J., Angel, J. L., O'Brien, W. F., Knuppel, R. A., kunye noMarsalisi, F. Ukusetyenziswa kwe-vitamin K yaphambi kokubeleka kuthintelo lokopha ebuchotsheni kwangaphambi kokubeleka. Ndingu. J. Obstet. Gynecol. Ngo-1988; 159: 774-779. Jonga i-abstract.
  61. UMotohara, K., Endo, F., kunye noMatsuda, I. Iziphumo zolawulo lwevithamini K kumanqanaba e-acarboxy prothrombin (PIVKA-II) kwiintsana ezisandul 'ukuzalwa. ILancet 8-3-1985; 2: 242-244. Jonga i-abstract.
  62. Ipropranolol ithintela ukopha kokuqala kwesisu kwizigulana ezingezizo ezesifo. Ingxelo yokugqibela yolingo oluninzi olungenamkhethe. Iprojekthi yase-Italiya yeMulticenter yePropranolol kuthintelo lokopha. UJepatol. Ngo-1989; 9: 75-83. Jonga i-abstract.
  63. UKazzi, N. J., Ilagan, N. B., Liang, K. C., Kazzi, G. M., Poland, R. L., Grietsell, L. A., Fujii, Y., kunye neBrans, Y. W.Ukulawulwa koomama ngevithamini K akuyiphuculi iprofayili yokuqina kweentsana ezizelwe ngaphambi kwexesha. Pediatrics 1989; 84: 1045-1050. Jonga i-abstract.
  64. Yang, Y. M., Simon, N., Maertens, P., Brigham, S., kunye noLiu, P. Uthutho loomama-olungekazalwa lwe-vitamin K1 kunye neziphumo zalo ekuxinaneni kwiintsana ezingaphambi kwexesha. J. Isigulana. Ngo-1989; 115: 1009-1013. Jonga i-abstract.
  65. Martin-Lopez, JE, Carlos-Gil, AM, Rodriguez-Lopez, R., Villegas-Portero, R., Luque-Romero, L., no-Flores-Moreno, S. [Iprophylactic vitamin K yokunqongophala kwe vithamin K usana olusandul 'ukuzalwa.]. Ifama yeendaba. Ngo-2011; 35: 148-55. Jonga i-abstract.
  66. Chow, C. K. Ukutya ukutya kwe-menaquinones kunye nomngcipheko wezehlo zomhlaza kunye nokufa. NdinguJ. Clin. Ngo-2010; 92: 1533-1534. Jonga i-abstract.
  67. Rees, K., Guraewal, S., Wong, YL, Majanbu, DL, Mavrodaris, A., Stranges, S., Kandala, NB, Clarke, A., noFranco, OH Ngaba ukusetyenziswa kwe-vitamin K kunxulunyaniswa ne-cardio-metabolic ukuphazamiseka? Uphengululo lwenkqubo. IMaturitas 2010; 67: 121-128. Jonga i-abstract.
  68. UNapolitano, M., Mariani, G., kunye noLapecorella, M. Hereditary idibene nokusilela kwezinto ezixhomekeke ku-vitamin K ezixhomekeke ekunqandeni. Inkedama. J. Rare. Dis. Ngo-2010; 5:21. Jonga i-abstract.
  69. UDougherty, K. A., Schall, J. I., kunye noStallings, V. A. Ubume obusezantsi bevithamini K ngaphandle kokongezwa kwabantwana nakubantu abadala abancinci abane-cystic fibrosis. NdinguJ. Clin. Ngo-2010; 92: 660-667. Jonga i-abstract.
  70. UNovotny, J. A., Kurilich, A. C., Britz, S. J., Baer, ​​D. J., kunye noClevidence, B. A. Ukufakwa kweVitamin K kunye ne-kinetics kwizifundo zabantu emva kokusetyenziswa kwe-13C enelebhile ye-phylloquinone evela kwi-kale. UBr. J. Nutrr. Ngo-2010; 104: 858-862. Jonga i-abstract.
  71. UJorgensen, F. S., Felding, P., Vinther, S., kunye noAndersen, G. E. Vitamin K ukuya kwi-neonates. Ukulawulwa ngokuchaseneyo nolawulo lwangaphakathi. Acta Paediatr. Ngo-1991; 80: 304-307. Jonga i-abstract.
  72. I-Nimptsch, K., Rohrmann, S., Kaaks, R., kunye neLinseisen, J. Ukutya ivithamin K yokutya ngokunxulumene nomhlaza kunye nokufa: iziphumo ezivela kwiqela lase-Heidelberg loPhando oluLindelekileyo lwaseYurophu kwiCancer and Nutrition (EPIC-Heidelberg ). NdinguJ. Clin. Ngo-2010; 91: 1348-1358. Jonga i-abstract.
  73. I-Yamauchi, M., Yamaguchi, T., Nawata, K., Takaoka, S., kunye ne-Sugimoto, T. Ubudlelwane phakathi kwe-undercarboxylated osteocalcin kunye ne-vitamin K yokungena, ukubuyiswa kwethambo, kunye nokuxinana kwamaminerali kubafazi abasempilweni. KwiKlinikhi. Ngo-2010; 29: 761-765. Jonga i-abstract.
  74. Shea, MK, Booth, SL, Gundberg, CM, Peterson, JW, Waddell, C., Dawson-Hughes, B., kunye noSaltzman, E. Ukutyeba kwabantu abadala kunxulunyaniswa ngokuqinisekileyo nokugxininiswa kwezicubu ze-adipose ye-vitamin K kwaye inxulunyaniswa nokujikeleza Iimpawu zesimo sevithamini K kumadoda nabasetyhini. UJutut. Ngo-2010; 140: 1029-1034. Jonga i-abstract.
  75. Ngokukodwa, uC. A., Crosby, D. D., kunye noHenderson-Smart, D. J. Vitamin K ngaphambi kokuzalwa kwangaphambi kokuthintela ukopha okwandayo kwangaphambi kokubeleka. Idatha yedatha yeCochrane. Ngo-2010; CD000229. Jonga i-abstract.
  76. Iwamoto, J. [Ukusebenza kokulwa nokwaphuka kwivithamini K]. Iiklinikhi. I-calcium 2009; 19: 1805-1814. Jonga i-abstract.
  77. UStevenson, M., Lloyd-Jones, M., kunye noPapaioannou, D. Vitamin K yokuthintela ukwaphuka kwabasetyhini abadala: uphononongo olucwangcisiweyo kunye novavanyo lwezoqoqosho. Itekhnoloji yezeMpilo. Ngo-2009; 13: iii-134. Jonga i-abstract.
  78. UYoshiji, H., Noguchi, R., Toyohara, M., Ikenaka, Y., Kitade, M., Kaji, K., Yamazaki, M., Yamao, J., Mitoro, A., Sawai, M., Isingeniso. Yoshida, M., Fujimoto, M., Tsujimoto, T., Kawaratani, H., Uemura, M., kunye noFukui, H. Umdibaniso wevithamini K2 kunye ne-angiotensin-eguqula i-enzyme inhibitor yonyusa ukubuyela kwakhona kwe-hepatocellular carcinoma. UJepatol. Ngo-2009; 51: 315-321. Jonga i-abstract.
  79. Iwamoto, J., Matsumoto, H., kunye noTakeda, T. Ukusebenza kwe-menatetrenone (i-vitamin K2) ngokuchasene ne-non-vertebral kunye ne-hip fractures kwizigulana ezinezifo zemithambo-luvo: uhlalutyo lweemeta ezintathu zolingo, ezilawulwayo. Eklinikhi. Uphando lweziyobisi. Ngo-2009; 29: 471-479. Jonga i-abstract.
  80. Crosier, MD, Peter, I., Booth, SL, Bennett, G., Dawson-Hughes, B., no-Ordovas, JM Umbutho wokulandelelana okwahlukahluka kwi-vitamin K epoxide reductase kunye ne-gamma-glutamyl carboxylase genes ngamanyathelo e-biochemical evithamini K iwonga. J. Nutr. Sci. Vitaminol. (Tokyo) 2009; 55: 112-119. Jonga i-abstract.
  81. Iwamoto, J., Sato, Y., Takeda, T., kunye noMatsumoto, H. Unyango oluphezulu lwevithamin K yokuncitshiswa kunciphisa ukwaphuka kwabafazi be-postmenopausal: uphononongo loncwadi. Isondlo Res. Ngo-2009; 29: 221-228. Jonga i-abstract.
  82. Shea, MK, O'Donnell, CJ, Hoffmann, U., Dallal, GE, Dawson-Hughes, B., Ordovas, JM, Price, PA, Williamson, MK, kunye neBooth, SL Vitamin K ukuxhaswa kunye nokuqhubela phambili komthambo wecoronary calcium kumadoda nakubasetyhini abadala. NdinguJ. Clin. Ngo-2009; 89: 1799-1807. Jonga i-abstract.
  83. Izishwankathelo zabaguli. Ngaba ivithamin K iluncedo kubantu abathathe kakhulu i-warfarin? UAnn. Interned. 3-3-2009; 150: I25. Jonga i-abstract.
  84. I-Kim, HS, iPaki, i-JW, iJang, i-JS, i-Kim, i-HJ, i-Shin, i-WG, uKim, u-KH, u-Lee, u-JH, uKim, uHY no-Jang, uMK amaxabiso okuqikelela e-alpha-fetoprotein kunye neprotein ebangelwa kukungabikho kwe-vitamin K okanye Umchasi-II kwi-hepatitis B enxulumene ne-hepatocellular carcinoma: isifundo esinokwenzeka. Jlin, Gastroenterol kunye no-J. Ngo-2009; 43: 482-488. Jonga i-abstract.
  85. Inoue, T., Fujita, T., Kishimoto, H., Makino, T., Nakamura, T., Nakamura, T., Sato, T., kunye no Yamazaki, K. Isifundo esilawulwa ngokungahleliwe malunga nokuthintela ukwaphuka kwamathambo ( YOKUFUNDA): Isigaba IV sonyango lweklinikhi ye-15-mg menatetrenone capsules. UJ Bone Miner, iMetab 2009; 27: 66-75. Jonga i-abstract.
  86. Cheung, AM, Tile, L., Lee, Y., Tomlinson, G., Hawker, G., Scher, J., Hu, H., Vieth, R., Thompson, L., Jamal, S., kunye UJosse, R. Vitamin K ukuxhaswa kwabasetyhini be-postmenopausal abane-osteopenia (uvavanyo lwe-ECKO): ityala elilawulwa ngokungahleliwe. IPL. I-10-14-2008; 5: e196. Jonga i-abstract.
  87. Ishida, Y. [Vitamin K2]. Iiklinikhi. I-calcium 2008; 18: 1476-1482. Jonga i-abstract.
  88. Hathaway, WE, Isarangkura, PB, Mahasandana, C., Jacobson, L., Pintadit, P., Pung-Amritt, P., kunye noGreen, GM Ukuthelekiswa komlomo kunye ne-parenteral ye-vitamin K prophylaxis yokuthintela isifo se-hemorrhagic emva kwexesha. usana olusandul 'ukuzalwa. J. Isigulana. Ngo-1991; 119: 461-464. Jonga i-abstract.
  89. Iwamoto, J., Takeda, T., kunye noSato, Y. Indima yevithamini K2 kunyango lwe-postmenopausal osteoporosis. Curr Iziyobisi Saf 2006; 1: 87-97. Jonga i-abstract.
  90. UMarti-Carvajal, A. J., Cortes-Jofre, M., kunye noMarti-Pena, A. J. Vitamin K yokuphuma kwegazi phezulu kwizigulana ezinezifo zesibindi. Idatha yedatha yeCochrane. Ngo-2008; CD004792. Jonga i-abstract.
  91. Ugqirha, D., Grey, V. L., Ferland, G., Gundberg, C., kunye noMhlaba, L. C. Ukusebenza kwedosi ephezulu ye-phylloquinone ekulungiseni ukusilela kwe-vitamin K kwi-cystic fibrosis. J.Cyst kunye neFibros. Ngo-2008; 7: 457-459. Jonga i-abstract.
  92. IMacdonald, HM, McGuigan, FE, Lanham-New, SA, Fraser, WD, Ralston, SH, kunye neReid, i-DM Vitamin K1Ukutya kunxulunyaniswa nokuxinana kwamathambo kunye nokuncipha kwethambo kubasetyhini bokuqala base-Scottish postmenopausal: abukho ubungqina bohlobo Unxibelelwano-lwe-nutrient kunye ne-apolipoprotein E polymorphisms. NdinguJ. Clin. Ngo-2008; 87: 1513-1520. Jonga i-abstract.
  93. UNimptsch, K., Rohrmann, S., kunye noLinseisen, J.Ukutya i-vitamin K kunye nomngcipheko womhlaza wesibeletho kwiqela lase-Heidelberg loPhando oluPhuphayo lwaseYurophu kwiCancer and Nutrition (EPIC-Heidelberg). NdinguJ. Clin. Ngo-2008; 87: 985-992. Jonga i-abstract.
  94. IHotta, N., Ayada, M., Sato, K., Ishikawa, T., Okumura, A., Matsumoto, E., Ohashi, T., kunye neKakumu, S. Iziphumo zevithamini K2 ukuphindeka kwizigulana i-hepatocellular carcinoma. IHepatogastroenterology 2007; 54: 2073-2077. Jonga i-abstract.
  95. Urquhart, D., Fitzpatrick, M., Cope, J., kunye noJaffe, A. Vitamin K echaza iipateni kunye nokujonga impilo kwithambo kubantwana base-UK abane-cystic fibrosis. J. Hum. Ukutya. Ngo-2007; 20: 605-610. Jonga i-abstract.
  96. IHosoi, T. [Unyango lwe-osteoporosis ephambili ene-vitamin K2]. KwiKlinikhi. 2007; 17: 1727-1730. Jonga i-abstract.
  97. UJones, K. S., Bluck, L. J., Wang, L. Y., kunye noCoward, W. A. ​​Indlela ezinzileyo yesotopu yokulinganisa ngaxeshanye ivithamini K1 (phylloquinone) kinetics kunye nokufakwa. I-Eur. J. Clin, iNutr. Ngo-2008; 62: 1273-1281. Jonga i-abstract.
  98. Knapen, M.H, Schurgers, L. J., kunye noVermeer, C.Ukuncedisa iVitamin K2 kuphucula i-hip bone geometry kunye ne-indices yamandla amathambo kubafazi abasemva kwexesha. Iinkcukacha Ngo-2007; 18: 963-972. Jonga i-abstract.
  99. Maas, A.H, van der Schouw, Y.T, Beijerinck, D., Deurenberg, J. J., Mali, W. P., Grobbee, D. E., kunye no-van der Graaf, Y.Ukutya kweVitamin K kunye nokubalwa kwimithambo yamabele. IMaturitas 3-20-2007; 56: 273-279. Jonga i-abstract.
  100. UDentali, F., Ageno, W., kunye noMnye, M. Unyango lwe-coarulinopathy ehambelana ne-coumarin: uphononongo olucwangcisiweyo kunye neendlela zokunyanga ezilungiselelwe. J. Ibhombu. Ngo-2006; 4: 1853-1863. Jonga i-abstract.
  101. Liu, J., Wang, Q., Zhao, J. H., Chen, YH, kunye noQin, G. L. Ukudityaniswa kwe-corticosteroids kunye ne-vitamin K yokuthintela ukopha okwenzeka ngaphakathi kwi-intraventricular hemorrhage kwiintsana ezisandula ukuzalwa ezingaphantsi kweeveki ezingama-35. J.Trop. Ngo-2006; 52: 355-359. Jonga i-abstract.
  102. U-Liu, J., Wang, Q., Gao, F., He, JW, kunye noZhao, JHUkulawulwa komama ngaphambi kokubeleka kwe-vitamin K1 kukhokelela ekwandiseni imisebenzi yezinto ezixhomekeke ku-vitamin K ezixhomekeke kwigazi le-umbilical kunye nasekunciphiseni kwenqanaba leziganeko. Ukuphuma kwegazi okwenzeka rhoqo ngaphakathi kubuchwephesha kwiintsana ngaphambi kwexesha. J. Perinat. Ngo-2006; 34: 173-176. Jonga i-abstract.
  103. UDezee, K.J, Shimeall, W.T, uDouglas, K. M., Shumway, N. M., kunye no-O'malley, P. G. Unyango lwe-anticoagulation egqithisileyo nge-phytonadione (vitamin K): uhlalutyo lweemeta. IArch Ingaphakathi. 2-27-2006; 166: 391-397. Jonga i-abstract.
  104. U-Thijssen, H. H., Vervoort, L. M., Schurgers, L. J., kunye no-Shearer, M. J. Menadione yimetabolite ye-vitamin yomlomo K. Br.J Nutr. Ngo-2006; 95: 260-266. Jonga i-abstract.
  105. UGoldstein, JN, Thomas, SH, Frontiero, V., Joseph, A., Engel, C., Snider, R., Smith, EE, Greenberg, SM, kunye noRosand, J. Ixesha lokulawulwa ngokutsha kweplasma efriziwe kunye nokulungiswa okukhawulezayo. ye-coagulopathy kwi-warfarin enxulumene nokuphuma kwegazi kwi-intracerebral hemorrhage.Ukubetha ngo-2006; 37: 151-155. Jonga i-abstract.
  106. Shetty, H. G., Backhouse, G., Bentley, D. P., kunye noRoutledge, P. A. Ukuguqulwa okusebenzayo kwe-warfarin-indased anticoagulation nge-vitamin K1 yedosi ephantsi. Ukuhluza. 1-23-1992; 67: 13-15. Jonga i-abstract.
  107. UAgeno, W., Garcia, D., Silingardi, M., Galli, M., kunye no-Crowther, M. Uvavanyo olungenamlinganiso ngokuthelekisa i-1 mg ye-vitamin K yomlomo ngaphandle konyango kulawulo lwe-coagulopathy enxulumene ne-warfarin kwizigulana ezinomatshini. Ivaluva zentliziyo. U-Am Am, uCardiol. 8-16-2005; 46: 732-733. Jonga i-abstract.
  108. IVillines, T. C., Hatzigeorgiou, C., Feuerstein, I. M., O'malley, P. G., kunye noTaylor, A. J. Vitamin K1 ukuthathwa kunye nokubalwa kwe-coronary. Umzobo weDiski. 2005; 16: 199-203. Jonga i-abstract.
  109. I-Yasaka, M., Sakata, T., Naritomi, H., kunye neMinematsu, K. Idosi efanelekileyo yeprothrombin yokugxininisa ekubuyiseleni umva i-anticoagulation yomlomo. Itromb. Ngo-2005; 115: 455-459. Jonga i-abstract.
  110. Sato, Y., Honda, Y., Hayashida, N., Iwamoto, J., Kanoko, T., kunye noSatoh, K. Ukusilela kweVitamin K kunye ne-osteopenia kubafazi abadala abanesifo sika-Alzheimer's. IArch.Phys.Med.Ulungiso. Ngo-2005; 86: 576-581. Jonga i-abstract.
  111. Sato, Y., Kanoko, T., Satoh, K., kunye no-Iwamoto, J. Menatetrenone kunye novithamini D2 abanezongezo zekhalsiyam kuthintela ukwaphuka okungaphenduliyo komqolo kubafazi abalupheleyo abanesifo sika-Alzheimer's. Amathambo 2005; 36: 61-68. Jonga i-abstract.
  112. I-Sasaki, N., Kusano, E., Takahashi, H., Ando, ​​Y., Yano, K., Tsuda, E., kunye no-Asano, Y. I-Vitamin K2 inqanda ukulahleka kwethambo okubangelwa yi-glucocorticoid ngokuyinxenye ngokuthintela ukunciphisa i-osteoprotegerin (OPG). UJ Bone Miner, iMetab 2005; 23: 41-47. Jonga i-abstract.
  113. I-Kalkwarf, i-H., I-Khoury, i-J., I-Bean, i-J, kunye ne-Elliot, i-J. Vitamin K, ukufunyanwa kwethambo, kunye nethambo kumantombazana. NdinguJ. Clin. Ngo-2004; 80: 1075-1080. Jonga i-abstract.
  114. Habu, D., Shiomi, S., Tamori, A., Takeda, T., Tanaka, T., Kubo, S., kunye noNishiguchi, S. Indima yevithamini K2 kuphuhliso lwe-hepatocellular carcinoma kwabasetyhini abane-cirrhosis yentsholongwane. yesibindi. IJAMA 7-21-2004; 292: 358-361. Jonga i-abstract.
  115. Dentali, F. kunye no-Ageno, W. Ulawulo lwe-coarulopathy ehambelana ne-coumarin kwisigulana esingophiyo: uphononongo olucwangcisiweyo. IHaematologica 2004; 89: 857-862. Jonga i-abstract.
  116. Lubetsky, A., Hoffman, R., Zimlichman, R., Eldor, A., Zvi, J., Kostenko, V., kunye no-Brenner, B. Ukusebenza kunye nokhuseleko lwe-prothrombin complex concentrate (i-Octaplex) yokutshintsha ngokukhawuleza i-anticoagulation yomlomo. Itromb. Ngo-2004; 113: 371-378. Jonga i-abstract.
  117. IBraam, L.A, Knapen, M.H, Geusens, P., Brouns, F., kunye neVermeer, C.Izinto ezichaphazela ukuphulukana nethambo kwiimbaleki zokunyamezela kwabasetyhini: isifundo seminyaka emibini yokulandela. Ndingu. J. Ezemidlalo. Ngo-2003; 31: 889-895. Jonga i-abstract.
  118. Lubetsky, A., Yonath, H., Olchovsky, D., Loebstein, R., Halkin, H., no-Ezra, D. Ukuthelekiswa komlomo vs intravenous phytonadione (ivithamin K1) kwizigulana ezine-anticoagulation egqithisileyo: ukufunda. IArch Ingaphakathi. 11-10-2003; 163: 2469-2473. Jonga i-abstract.
  119. UBraam, L. A., Knapen, M.H, Geusens, P., Brouns, F., Hamulyak, K., Gerichhausen, M. J., kunye noVermeer, uC. Vitamin K1 ukongezwa kuthintela ukulahleka kwethambo kubafazi abasemva kwamadoda abaphakathi kweminyaka engama-50 nama-60 ubudala. Uluhlu lweethambo Int. Ngo-2003; 73: 21-26. Jonga i-abstract.
  120. I-Cornelissen, EA, Kollee, LA, De Abreu, RA, van Baal, JM, Motohara, K., Verbruggen, B., kunye neMonnens, LA Iziphumo zomlomo kunye ne-intramuscular vitamin K prophylaxis kwi-vitamin K1, PIVKA-II, kunye ne-clotting izinto kwiintsana ezincancisayo. IArch. Umntwana 1992; 67: 1250-1254. Jonga i-abstract.
  121. Malik, S., Udani, R.H, Bichile, S. K., Agrawal, R. M., Bahrainwala, A., kunye noTilaye, S. Ukuthelekisa isifundo somlomo xa kuthelekiswa ne-vitamin K enesitofu. Isilwanyana saseIndiya. Ngo-1992; 29: 857-859. Jonga i-abstract.
  122. I-VIETTI, T. J., MURPHY, T. P., JAMES, J. A., kunye ne-PRITCHARD, J. A. Ukuqwalaselwa kusetyenziso lweprophylactic yevithamini Kin usana olusandul 'ukuzalwa. J. Isigulana. Ngo-1960; 56: 343-346. Jonga i-abstract.
  123. Ithebhu, MM, iLanga, A., Zhou, C., Grun, F., Errandi, J., Romero, K., Pham, H., Inoue, S., Mallick, S., Lin, M., Forman , BM, kunye neBlumberg, B.Umiselo weVitamin K2 wethambo i-homeostasis iphakathi yi-steroid kunye ne-xenobiotic receptor SXR. J Biol. IChem. 11-7-2003; 278: 43919-43927. Jonga i-abstract.
  124. Sorensen, B., Johansen, P., Nielsen, G. L., Sorensen, J. C., kunye no-Ingerslev, J.Ukuguqulwa kweRatio eQhelekileyo yaMazwe ngaMazwe nge-recombinant activated factor VII kwinkqubo yokopha luvo ngexesha le-warfarin thromboprophylaxis: imiba yeklinikhi kunye ne-biochemical. Igazi leCoagul. IFibrinolysis 2003; 14: 469-477. Jonga i-abstract.
  125. Poli, D., Antonucci, E., Lombardi, A., Gensini, GF, Abbate, R., kunye noPrisco, D. Ukhuseleko kunye nokusebenza kolawulo lweedosi ezisezantsi zomlomo wevithamini K1 kulawulo kwizigulana ezingaphandle kwi-warfarin okanye i-acenocoumarol ngokugqithileyo. Ukuchasana ne-antioagulation. IHaematologica 2003; 88: 237-238. Jonga i-abstract.
  126. Yasaka, M., Sakata, T., Minematsu, K., kunye noNaritomi, H. Ukulungiswa kwe-INR yi-prothrombin complex concentrate kunye ne-vitamin K kwizigulana ezinengxaki ye-warfarin enxulumene nokopha. Itromb. 10-1-2002; 108: 25-30. Jonga i-abstract.
  127. IBooth, SL, Broe, KE, Gagnon, DR, Tucker, KL, Hannan, MT, McLean, RR, Dawson-Hughes, B., Wilson, PW, Cupples, LA, kunye neKiel, DP Vitamin K ukungenisa kunye nokuxinana kwamaminerali kwabasetyhini nakumadoda. NdinguJ. Clin. Ngo-2003; 77: 512-516. Jonga i-abstract.
  128. UDeveras, R. A. noKessler, C. M. Ukubuyiselwa umva kwe-warfarin-indased anticoagulation with recombinant factor factor VIIa concentrate. UAnn. Interned. 12-3-2002; 137: 884-888. Jonga i-abstract.
  129. URiegert-Johnson, D.L kunye noVolcheck, G. W.Izehlo ze-anaphylaxis elandela i-phytonadione efakwa ngaphakathi (ivithamini K1): uphononongo lweminyaka emi-5 lokujonga kwakhona. UAnn. Isifo se-Asma Esibangelwa Kukwalana Neempawu Zomzimba. Ngo-2002; 89: 400-406. Jonga i-abstract.
  130. Ngokubanzi, MA, Douketis, JD, Schnurr, T., Steidl, L., Mera, V., Ultori, C., Venco, A., kunye no-Ageno, W. Oral ivithamin K yehlisa umlinganiso oqhelekileyo wamazwe aphesheya ngokukhawuleza kunendlela engaphantsi i-vitamin K kunyango lwe-warfarin-ehambelana ne-coagulopathy. Uvavanyo olungenamkhethe, olulawulwayo. UAnn. Interned. 8-20-2002; 137: 251-254. Jonga i-abstract.
  131. UAgeno, W., Ngokunye, M., Steidl, L., Ultori, C., Mera, V., Dentali, F., Squizzato, A., Marchesi, C., kunye noVenco, A. Idosi encinci ye-vitamin K yomlomo. Ukuguqula i-acenocoumarol-indased coagulopathy: ityala elilawulwa ngokungahleliwe. Ukuhluza. Ngo-2002; 88: 48-51. Jonga i-abstract.
  132. Sato, Y., Honda, Y., Kaji, M., Asoh, T., Hosokawa, K., Kondo, I., kunye noSatoh, K. Ukuphucula i-osteoporosis yi-menatetrenone kwizigulane zesifo sabantu abadala se-Parkinson abane-vitamin D . Ithambo 2002; 31: 114-118. Jonga i-abstract.
  133. U-Olson, R. E., Chao, J., Graham, D., Bates, M. W., kunye noLewis, uJH H.Umzimba wonke we-phylloquinone kunye nokungena kwayo kwizifundo zabantu kumanqanaba amabini e-vitamin K. UBr. J. Nutrr. Ngo-2002; 87: 543-553. Jonga i-abstract.
  134. UAndersen, P. kunye no-Godal, H. C. Ukuxelwa kwangaphambili kwemisebenzi ye-anticoagulant ye-warfarin ngamaxabiso amancinci evithamini K. Acta Med. Ngo-1975; 198: 269-270. Jonga i-abstract.
  135. U-Preston, F. E., Laidlaw, S., Sampson, B., kunye no Khitshi, S. Ukubuyela umva ngokukhawuleza kwe-anticoagulation yomlomo kunye ne-warfarin yi-prothrombin complex concentrate (Beriplex): ukusebenza kunye nokhuseleko kwizigulana ezingama-42. UBr. J. Haematol. Ngo-2002; 116: 619-624. Jonga i-abstract.
  136. U-Evans, G., Luddington, R., kunye no-Baglin, u-T.Beriplex P / N ubuyisela umva kakhulu i-warfarin-indased overanticoagulation kwangoko nangokupheleleyo kwizigulana ezibonisa ukopha okukhulu. UBr. J. Haematol. 2001; 115: 998-1001. Jonga i-abstract.
  137. Iwamoto, J., Takeda, T., kunye ne-Ichimura, S. Iziphumo ze-menatetrenone kwithambo lexinano lwamaminerali kunye neziganeko zokuqhekeka kwe-vertebral kuma-postmenopausal kwabasetyhini abane-osteoporosis: ukuthelekisa nefuthe le-etidronate. J.Oththop. 2001; 6: 487-492. Jonga i-abstract.
  138. Sato, Y., Kaji, M., Tsuru, T., Satoh, K., kunye noKondo, I. Ukunqongophala kweVitamin K kunye ne-osteopenia kwivithamin D engenabantu abasele bekhulile abanesifo sikaParkinson. IArch.Phys.Med.Ulungiso. Ngo-2002; 83: 86-91. Jonga i-abstract.
  139. UWatson, H. G., Baglin, T., Laidlaw, S. L., Makris, M., kunye noPreston, F. E. Ukuthelekiswa kokusebenza kunye nenqanaba lokuphendula kwi-Vitamin K yomlomo kunye ne-intravenous ekubuyiseni i-anticoagulation engaphezulu kwe-warfarin. UBr. J. Haematol. 2001; 115: 145-149. Jonga i-abstract.
  140. Kumar, D., Greer, F. R., Super, D. M., Suttie, J. W., and Moore, J. J. Vitamin K inqanaba labantwana abazelwe ngaphambi kwexesha: iimpembelelo kwizindululo zangoku. Iipedatifikethi 2001; 108: 1117-1122. Jonga i-abstract.
  141. UNishiguchi, S., Shimoi, S., Kurooka, H., Tamori, A., Habu, D., Takeda, T., kunye noKubo, S. Uvavanyo olulinganisiweyo lokuvavanywa kwevithamini K2 yokulahleka kwethambo kwizigulana ezine-cirrhosis yokuqala. . UJepatol. 2001; 35: 543-545. Jonga i-abstract.
  142. Wilson, DC, Rashid, M., Durie, PR, Tsang, A., Kalnins, D., Andrew, M., Corey, M., Shin, J., Tullis, E., kunye nePencharz, unyango lwe-PB lwevithamini K ukusilela kwe-cystic fibrosis: Ukusebenza kwendibaniselwano yamafutha e-soluble yemihla ngemihla. J. Isigulana. 2001; 138: 851-855. Jonga i-abstract.
  143. I-Pendry, K., Bhavnani, M., kunye ne-Shwe, K. Ukusetyenziswa kwe-vitamin K yomlomo yokubuyisela umva kwi-warfarinization. UBr. J. Haematol. 2001; 113: 839-840. Jonga i-abstract.
  144. UFondevila, C. G., Grosso, S.H, Santarelli, M.T, kunye noPinto, M. D.Ukuguqulwa kwe-anticoagulation yomlomo egqithileyo ngomthamo ophantsi womlomo wevithamini K1 xa kuthelekiswa nokupheliswa kwe-acenocoumarine. Isifundo esinokubakho, esingenamkhethe, nesivulekileyo. Igazi leCoagul. I-fibrinolysis 2001; 12: 9-16. Jonga i-abstract.
  145. ICartmill, M., iDolan, G., Byrne, J. L., kunye ne-Byrne, P. O. Prothrombin gxila ekugxileni kwi-anticoagulant yomlomo ekubuyiseleni kwimeko engxamisekileyo ye-neurosurgical. UBr. J. Neurosurg. Ngo-2000; 14: 458-461. Jonga i-abstract.
  146. Iwamoto, J., Takeda, T., kunye ne-Ichimura, S. Iziphumo zolawulo oludibeneyo lwe-vitamin D3 kunye ne-vitamin K2 kwithambo le-mineral density ye-lumbar spine kuma-postmenopausal women ane-osteoporosis. J.Oththop. Ngo-2000; 5: 546-551. Jonga i-abstract.
  147. Ngokubanzi, MA, Julian, J., McCarty, D., Douketis, J., Kovacs, M., Biagoni, L., Schnurr, T., McGinnis, J., Gent, M., Hirsh, J., kunye UGinsberg, J. Unyango lwe-coagulopathy enxulumene ne-warfarin kunye ne-vitamin K yomlomo: ityala elilawulwa ngokungahleliwe. ILancet 11-4-2000; 356: 1551-1553. Jonga i-abstract.
  148. UPuckett, R. M. kunye no-Offringa, M. Prophylactic uvithamini K wevithamini K ukuswela ukopha kwii-neonates. Idatha yedatha yeCochrane. Ngo-2000; CD002776. Jonga i-abstract.
  149. Patel, R. J., Witt, D. M., Saseen, J., Tillman, D. J., noWilkinson, D. S. Randomised, placebo-controlled trial of oral phytonadione for anticoagulation kakhulu. I-Pharmacotherapy 2000; 20: 1159-1166. Jonga i-abstract.
  150. UHung, A., Singh, S., kunye noTait, R. C. Isifundo esinokubakho ngokungacwangciswanga ukufumanisa idosi efanelekileyo ye-vitamin K efakwe umva ekubuyiseleni i-warfarinization engaphaya. UBr. J. Haematol. Ngo-2000; 109: 537-539. Jonga i-abstract.
  151. UHylek, E. M., Chang, YC, Skates, S., Hughes, R. A., kunye no-Singer, D. E. Ukufundwa okulindelweyo kweziphumo zezigulana ezigulayo ezine-warfarin anticoagulation. IArch Ingaphakathi. 6-12-2000; 160: 1612-1617. Jonga i-abstract.
  152. I-Brophy, M.T, Fiore, L.D, kunye noDeykin, D. Unyango olusezantsi lweVithamin K kunyango kwizigulana ezi-Anticoagulated: Isifundo sokufumana idosi. Ingcungcu. Ngo-1997; 4: 289-292. Jonga i-abstract.
  153. URaj, G., Kumar, R., kunye noMcKinney, W. P. Ikhosi yexesha lokuguqula impembelelo ye-anticoagulant ye-warfarin nge-phytonadione efakwa ngaphakathi nangaphantsi. IArch Ingaphakathi. 12-13-1999; 159: 2721-2724. Jonga i-abstract.
  154. Ngu-Byrd, D., Stephens, M. A., Hamann, G. L., no-Dorko, C. I-phytonadione engaphantsi kwe-subcutaneous phytonadione yokuguqula ukuphakanyiswa kwe-warfarin-induction ye-International Normalized Ratio. NdinguJ J. wezeMpilo Syst. 11-15-1999; 56: 2312-2315. Jonga i-abstract.
  155. UBoulis, N. M., Bobek, M. P., Schmaier, A., kunye noHoff, J.T.Ukusetyenziswa kwe-factor IX complex in warfarin-related intracranial hemorrhage. Neurosurgery 1999; 45: 1113-1118. Jonga i-abstract.
  156. URashid, M., Durie, P., Andrew, M., Kalnins, D., Shin, J., Corey, M., Tullis, E., kunye nePencharz, P. B. Ukusasazeka kwe-vitamin K yokunqongophala kwe-cystic fibrosis. NdinguJ. Clin. Ngo-1999; 70: 378-382. Jonga i-abstract.
  157. UBooth, S. L., O'Brien-Morse, M. E., Dallal, G. E., Davidson, K. W., noGundberg, C. M. Impendulo yesimo sevithamin K kukungeniswa okuhlukeneyo kunye nemithombo yokutya okune-phylloquinone: uthelekiso lwabantu abadala nabadala. NdinguJ. Clin. Ngo-1999; 70: 368-377. Jonga i-abstract.
  158. I-Somekawa, Y., Chigughi, M., Harada, M., kunye no-Ishibashi, T. Ukusetyenziswa kwe-vitamin K2 (menatetrenone) kunye ne-1,25-dihydroxyvitamin D3 kuthintelo lokuphulukana nethambo okubangelwa yi-leuprolide. UJ. Clin, uEndocrinol, kunye neMetab 1999; 84: 2700-2704. Jonga i-abstract.
  159. Sato, Y., Tsuru, T., Oizumi, K., kunye noKaji, M. Vitamin K ukunqongophala kunye ne-osteopenia kwimilenze echaphazelekileyo yokungasasebenzi kakuhle kwezigulana ezinesifo esinevithamin D. Ndingu. J. Phys. Ukulungiswa. Ngo-1999; 78: 317-322. Jonga i-abstract.
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  162. UBolton-Smith, C., McMurdo, ME, uPaterson, CR, uMole, u-PA, uHarvey, uJM, uFenton, uSt, uPrynne, uCJ, uMishra, uGD, noShearer, uMJ Uvavanyo lweminyaka emibini olulawulwa ngokungenamkhethe lwevithamini K1 (phylloquinone ) kunye nevithamini D3 kunye necalcium kwimpilo yethambo labafazi abadala. J. Amathambo eMigodi. Ngo-2007; 22: 509-519. Jonga i-abstract.
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