Mycophenolate

Umxholo

• Ngaphambi kokuba uthathe i-mycophenolate,
• I-Mycophenolate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
• Iimpawu libanda kungaquka oku kulandelayo:

Umngcipheko weziphene zokuzalwa:

I-Mycophenolate mayingathathwa ngabafazi abakhulelweyo okanye abanokukhulelwa. Kukho umngcipheko omkhulu wokuba i-mycophenolate ibangele ukuphuphuma kwesisu (ukuphulukana nokukhulelwa) ngexesha leenyanga ezintathu zokuqala zokukhulelwa okanye kuya kubangela ukuba umntwana azalwe enesiphene sokuzalwa (iingxaki ezikhoyo ekuzalweni).

Akufanele uthathe i-mycophenolate xa ukhulelwe okanye ukuba unokukhulelwa. Kuya kufuneka ube novavanyo lokukhulelwa olubi ngaphambi kokuba uqalise unyango lwakho nge-mycophenolate, kwakhona emva kweentsuku eziyi-8 ukuya kwezi-10, kunye nokuqeshwa rhoqo. Kuya kufuneka usebenzise ulwamkelo lokuzalwa okwamkelekileyo ngexesha lonyango lwakho, kunye nakwiiveki ezi-6 emva kokuba uyeke ukuthatha i-mycophenolate. Ugqirha wakho uya kukuxelela ukuba zeziphi iindlela zolawulo lokuzalwa ezamkelekileyo ukuba uzisebenzise. I-Mycophenolate inokunciphisa ukusebenza kwezicwangcisi zomlomo (iipilisi zolawulo lokuzalwa), ke ngoko kubaluleke ngakumbi ukusebenzisa uhlobo lwesibini lolawulo lokuzalwa kunye nolu hlobo lokuthintela ukukhulelwa.

Ukuba uyindoda eneqabane lomfazi elinokuthi likhulelwe, kuya kufuneka usebenzise ulawulo olwamkelekileyo lokuzalwa ngexesha lonyango kwaye ubuncinci kwiintsuku ezingama-90 emva kwedosi yakho yokugqibela. Musa ukunikela ngesidoda ngexesha lonyango kwaye ubuncinci kwiintsuku ezingama-90 emva kwedosi yakho yokugqibela.

Biza ugqirha wakho ngoko nangoko ukuba ucinga ukuba wena okanye iqabane lakho, ukhulelwe okanye ukuba uphoswa lixesha lokuya exesheni.

Ngenxa yokuba kungenzeka ukuba umnikelo wakho uye kowasetyhini onokuba ukhulelwe okanye okhulelweyo, musa ukunikela ngegazi ngexesha lonyango lwakho kwaye ubuncinci iiveki ezi-6 emva kwethamo lakho lokugqibela.

Iingozi zezifo ezinzulu:

I-Mycophenolate yenza buthathaka amajoni omzimba kwaye inganciphisa amandla akho okulwa usulelo. Hlamba izandla zakho rhoqo kwaye uphephe abantu abagulayo ngelixa uthatha la mayeza. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: umkhuhlane, umqala obuhlungu, ukugodola, okanye ukukhohlela; ukugruzuka okanye ukopha okungaqhelekanga; iintlungu okanye ukutshisa ngexesha lokuchama; ukuchama rhoqo; inxeba okanye isilonda esibomvu, eshushu, okanye esinganyangekiyo; i-drainage kwilonda lesikhumba; ubuthathaka ngokubanzi, ukudinwa kakhulu, okanye ukugula; iimpawu '' zomkhuhlane '' okanye '' ukubanda ''; iintlungu okanye ukudumba entanyeni, emiphakathini, okanye emakhwapheni; amabala amhlophe emlonyeni okanye emqaleni; izilonda ezibandayo; amadyungudyungu; intloko ebuhlungu okanye indlebe; okanye ezinye iimpawu zosulelo.

Unokosulelwa zintsholongwane ezithile okanye ibhaktiriya kodwa ungabinazimpawu zosulelo. Ukuthatha i-mycophenolate kwandisa umngcipheko wokuba ezi zifo ziya kuba qatha kwaye zibangele iimpawu. Tshela ugqirha wakho ukuba unayo nayiphi na intsholongwane, njenge-Hepatitis B okanye C, kubandakanywa nosulelo olungabangeli iimpawu.

I-Mycophenolate inokunyusa umngcipheko wokuba uza kuphuhlisa i-leukoencephalopathy eqhubekayo (PML; isifo esinqabileyo sobuchopho esinganyangekiyo, esinokuthintelwa, okanye esinganyangekiyo esihlala sibangela ukufa okanye ukukhubazeka okukhulu). Xelela ugqirha wakho ukuba wakhe wanayo okanye wakha wanayo i-PML, okanye enye imeko echaphazela amajoni akho omzimba anjenge-HIV (HIV); ufumene isifo se-immunodeficiency syndrome (i-AIDS); sarcoidosis (imeko ebangela ukudumba emiphungeni kwaye ngamanye amaxesha kwamanye amalungu omzimba); i-leukemia (umhlaza obangela ukuba iiseli ezininzi zegazi ziveliswe kwaye zikhutshelwe egazini); okanye i-lymphoma. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: ubuthathaka kwelinye icala lomzimba okanye emilenzeni; ubunzima okanye ukungakwazi ukulawula izihlunu zakho; ukudideka okanye ubunzima bokucinga ngokucacileyo; ukungazinzi; ukulahleka kwememori; kunzima ukuthetha okanye ukuqonda ukuba bathini abanye; okanye ukungabikho komdla okanye inkxalabo yemisebenzi yesiqhelo okanye izinto oqhele ukuzikhathalela.

I-Mycophenolate inokunyusa umngcipheko wokuphuhlisa iintlobo ezithile zomhlaza, kubandakanya i-lymphoma (uhlobo lomhlaza olukhula kwinkqubo ye-lymph) kunye nomhlaza wolusu. Tshela ugqirha wakho ukuba wena okanye nabani na kusapho lwakho ukhe waba nomhlaza wolusu. Kunqande ukubekwa elangeni okwenyani nokungeyomfuneko ngokungekho mthethweni (iibhedi zokususa, izibane zelanga) kunye nonyango oluncinci kwaye unxibe iimpahla zokuzikhusela, iiglasi zelanga, kunye nelanga (elinendawo ye-SPF engama-30 okanye ngaphezulu). Oku kuya kunceda ukunciphisa umngcipheko wokuba nomhlaza wolusu. Fowunela ugqirha wakho ukuba unazo naziphi na kwezi mpawu zilandelayo: iintlungu okanye ukudumba entanyeni, emiphakathini, okanye emakhwapheni; ulusu olutsha okanye isilonda; utshintsho kubungakanani okanye umbala kwimole; isikhumba esimdaka okanye esimnyama solusu (esibuhlungu) esinemiphetho engalinganiyo okanye enye indawo yesilonda engafani nenye; utshintsho lolusu; izilonda ezingapholiyo; umkhuhlane ongachazwanga; ukudinwa okungapheliyo; okanye ukunciphisa umzimba.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-mycophenolate kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi http://www.fda.gov/Drugs ukufumana isiKhokelo seyeza.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-mycophenolate.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-mycophenolate.

I-Mycophenolate (i-CellCept) isetyenziswa namanye amayeza ukunceda ukuthintela ukungamkelwa komzimba nangaphezulu abafumene ukufakelwa kwezintso. I-Mycophenolate (Myfortic) isetyenziswa namanye amayeza ukunceda ukuthintela umzimba ukwala ukufakelwa kwezintso. I-Mycophenolate ikudidi lwamayeza abizwa ngokuba zii-immunosuppressive agents. Isebenza ngokwenza buthathaka amajoni omzimba ukuze ingayi kuhlasela kwaye iyala ilungu elifakelweyo.

I-Mycophenolate iza njengecapsule, ithebhulethi, ukukhutshwa okulibazisekileyo (kukhupha iyeza emathunjini) ithebhulethi, kunye nokumiswa (ulwelo) ukuthatha ngomlomo. Ihlala ithathwa kabini ngemini kwisisu esingenanto (iyure e-1 ngaphambi okanye iiyure ezi-2 emva kokutya okanye ukusela, ngaphandle kokuba ugqirha wakho ukuxelele ngenye indlela). Thatha i-mycophenolate malunga namaxesha afanayo yonke imihla, kwaye uzame ukubeka iidosi zakho malunga neeyure ezili-12 ngaphandle. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-mycophenolate ngokuchanekileyo. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Iyeza elikwithebhulethi yokukhululwa ebambezelekileyo (iMyfortic) ifunxwa ngokwahlukileyo ngumzimba kunamayeza okumiswa, ithebhulethi kunye necapsule (CellCept). Ezi mveliso azinakutshintshwa enye nenye. Ngalo lonke ixesha ugcwaliswa ngugqirha, qiniseka ukuba uyifumene imveliso efanelekileyo. Ukuba ucinga ukuba ufumene iyeza elingalunganga, thetha nogqirha wakho kunye nosokhemisti kwangoko.

Ginya amacwecwe, iipilisi zokukhupha ukulibaziseka, kunye neepilisi. ungahluleli, ungahlaleli, okanye uzityumze. Musa ukuvula iifomsile.

Musa ukudibanisa ukumiswa kwe-mycophenolate kunye nawaphi na amanye amayeza.

Lumka ungachitheki ngokumiswa okanye ukufefa kulusu lwakho. Ukuba ulusu lumisiwe, hlamba loo ndawo kakuhle ngesepha namanzi. Ukuba ufumana ukumiswa emehlweni akho, coca ngamanzi alula. Sebenzisa iitawuli zamaphepha ezimanzi ukosula naziphi na izinto ezingamanzi ezichithekileyo.

I-Mycophenolate iyanceda ukunqanda ukwala ukufakelwa komzimba kuphela xa usela amayeza. Qhubeka uthathe i-mycophenolate nokuba uziva uphilile. Ungayeki ukuthatha i-mycophenolate ngaphandle kokuthetha nogqirha wakho.

I-Mycophenolate ikwasetyenziselwa ukunyanga isifo sikaCrohn (imeko apho umzimba uhlasela khona ulwelo lwendlela yokugaya, ebangela iintlungu, urhudo, ukunciphisa umzimba kunye nomkhuhlane). Thetha nogqirha wakho malunga neengozi zokusebenzisa la mayeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-mycophenolate,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-mycophenolate, mycophenolic acid, nawaphi na amanye amayeza, okanye nasiphi na isithako esikwimveliso ye-mycophenolate okanye ye-mycophenolic acid oyisebenzisayo. Ukuba uthatha ulwelo lwe-mycophenolate, xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-aspartame okanye i-sorbitol. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: amalahle asebenzayo; i-acyclovir (iZovirax); ii-antibiotics ezithile ezifana ne-amoxicillin kunye ne-clavulanic acid (Augmentin), ciprofloxacin (Cipro) ,, kunye ne-sulfamethoxazole / trimethoprim (Bactrim); azathioprine (Azasan, Imuran); cholestyramine (Prevalite); ganciclovir (iCytovene, iValcyte); amanye amayeza acinezela amajoni omzimba; isavuconazonium (Cresemba); probenecid (Unobumba); Iiproton pump inhibitors ezifana ne-lansoprazole (Dexilant, Prevacid) kunye ne-pantoprazole (Protonix); irifampin (Rifadin, Rimactane, eRifamate, Rifater); telmisartan (Micardis, eTwynsta); i-valacyclovir (iValtrex); kunye ne-valganciclovir (Valcyte). Xelela ugqirha wakho ukuba uthatha indibaniselwano ye-norfloxacin (Noroxin) kunye ne-metronidazole (Flagyl). Amanye amayeza amaninzi anokusebenzisana ne-mycophenolate, ke qiniseka ukuxelela ugqirha wakho malunga nawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Qiniseka ukuba uxelele ugqirha wakho ukuba uyeka ukuthatha nawaphi na amayeza akho. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukuba uthatha i-sevelamer (Renagel, Renvela), okanye ii-antacids ezine-magnesium okanye i-aluminium, zithathe iiyure ezi-2 emva kokuba uthathe i-mycophenolate.
• xelela ugqirha wakho ukuba ukhe wakha wanaso okanye wakha waba ne-Lesch-Nyhan syndrome okanye i-Kelley-Seegmiller syndrome (izifo esizuze njengelifa ezibangela amanqanaba aphezulu ezinto ezithile egazini, iintlungu ezidibeneyo, kunye neengxaki zokuhamba nokuziphatha); i-anemia (inani elisezantsi kuneliqhelekileyo leeseli ezibomvu zegazi); neutropenia (ngaphantsi kwenani eliqhelekileyo leeseli ezimhlophe zegazi); izilonda okanye nasiphi na isifo esichaphazela isisu sakho, amathumbu, okanye inkqubo yokwetyisa; naluphi na uhlobo lomhlaza; okanye isifo sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba uncelisa.
• Kuya kufuneka uyazi ukuba i-mycophenolate inokukwenza wozele, udideke, ube nesiyezi, ube nentloko elula, okanye ubangele ukushukuma okungalawulekiyo kwelungu lomzimba. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
• awunalo ugonyo ngaphandle kokuthetha nogqirha wakho. Buza ugqirha wakho ukuba ngaba unokufumana isitofu sokugonya somkhuhlane ngaphambi okanye ngexesha lonyango lwakho kuba ukuthatha i-mycophenolate kunokunyusa umngcipheko wosulelo.
• ukuba unayo i-phenylketonuria (PKU, imeko ezuzwe njengelifa apho ukutya okukhethekileyo kufuneka kulandelwe ukuthintela ukudodobala kwengqondo), kuya kufuneka wazi ukuba ukumiswa kwe-mycophenolate kuqulethe i-aspartame, umthombo we-phenylalanine.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uthatha ithebhulethi ye-mycophenolate, i-capsule, okanye ukumiswa (i-Cellcept) thabatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba idosi elandelayo ingaphantsi kweeyure ezingama-2, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Ukuba uthatha i-mycophenolate yokulibaziseka kwithebhulethi (iMyfortic) thabatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Mycophenolate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukuqhina
• isisu esibuhlungu okanye ukudumba
• isicaphucaphu
• ukugabha
• ubunzima bokulala okanye ukulala
• iintlungu, ngakumbi ngasemva, izihlunu, okanye amalungu
• intloko ebuhlungu
• irhasi
• ukuhlaba, ukurhawuzelela, okanye ukutsha kwesikhumba
• ukuqina kwemisipha okanye ubuthathaka

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• urhudo, isisu esibuhlungu ngesiquphe
• ukudumba kwezandla, iingalo, iinyawo, amaqatha okanye imilenze esezantsi
• ubunzima bokuphefumla
• iintlungu zesifuba
• irhashalala
• ukurhawuzelela
• ukubetha kwentliziyo ngokukhawuleza
• isiyezi
• isiqaqa
• ukunqongophala kwamandla
• ulusu oluthuthu
• ukopha okungaqhelekanga okanye ukugruzuka
• izitulo ezimnyama kunye nokulinda
• Igazi elibomvu ilindle
• ukugabha okunegazi
• ukugabha okujongeka njengendawo yekofu
• igazi kumchamo
• mthubi ulusu okanye amehlo

I-Mycophenolate inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Ukunqunyanyiswa kweMycophenolate kunokugcinwa kwifriji. Musa ukumisa ukumiswa kwe-mycophenolate. Lahla nakuphi na ukumiswa okungasetyenziswanga kwe-mycophenolate emva kweentsuku ezingama-60.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isisu esibuhlungu
• isicaphucaphu
• ukugabha
• isilungulela
• urhudo
• umkhuhlane, umqala obuhlungu, ingqele, ukukhohlela nezinye iimpawu zosulelo

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• CellCept^®
• Yimnandi^®