Umbhali: Janice Evans
Umhla Wokudalwa: 23 Eyekhala 2021
Hlaziya Umhla: 16 Eyenkanga 2024
Anonim
Oxcarbazepine - Mechanism, side effects, precautions & uses
Ividiyo: Oxcarbazepine - Mechanism, side effects, precautions & uses

Umxholo

I-Oxcarbazepine (iTrileptal) isetyenziswa yodwa okanye ngokudibeneyo namanye amayeza ukulawula iintlobo ezithile zokubanjwa kwabantu abadala nabantwana. Iipilisi zokukhupha i-Oxcarbazepine ezandisiweyo (iOxtellar XR) zisetyenziswa ngokudibanisa namanye amayeza ukulawula iintlobo ezithile zokubanjwa kwabantu abadala kunye nabantwana abaneminyaka emi-6 nangaphezulu. I-Oxcarbazepine ikwiklasi yamayeza abizwa ngokuba zii-anticonvulsants. Isebenza ngokunciphisa izinto ezingaqhelekanga zombane kwingqondo.

I-Oxcarbazepine iza njengepilisi, ithebhulethi ekhulisiweyo, kunye nokumiswa (ulwelo) ukuthatha ngomlomo. Ithebhulethi kunye nokumiswa kuhlala kuthathwa rhoqo emva kweeyure ezili-12 (kabini ngemini) kunye okanye ngaphandle kokutya. Ithebhulethi yokukhululwa eyandisiweyo ihlala ithathwa kanye ngemini kwisisu esingenanto, iyure enye ngaphambi okanye iiyure ezi-2 emva kwesidlo. Thatha i-oxcarbazepine ngeenxa zonke ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-oxcarbazepine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.


Hlanganisa ukunqunyanyiswa kakuhle phambi kokusetyenziswa ngakunye ukuxuba amayeza ngokulinganayo. Sebenzisa isirinji yomlomo yedosi eyeza nonyango ukurhoxisa inani elifanelekileyo lokumiswa kwibhotile. Ungaginya ukumiswa ngokuthe ngqo kwisirinji okanye ungakuxuba ngeglasi encinci yamanzi kwaye uginye lo mxube. Hlamba isirinji ngamanzi ashushu kwaye uyivumele yome kakuhle emva kokusetyenziswa.

Ginya iipilisi ezikhutshiweyo ezipheleleyo ngamanzi okanye ngolunye ulwelo; ungahluleli, ungahlaleli, okanye uzityumze.

Ugqirha wakho uya kukuqala ngedosi esezantsi ye-oxcarbazepine kwaye ngokuthe chu ayonyuse idosi yakho, hayi rhoqo rhoqo kube kanye kwiintsuku ezi-3. Ukuba ubuthatha elinye iyeza ukunyanga ukuxhuzula kwakho kwaye utshintshela kwi-oxcarbazepine, ugqirha wakho unokunciphisa ngokuthe ngcembe idosi yakho yamanye amayeza ngelixa usonyusa idosi yakho ye-oxcarbazepine. Landela le miyalelo ngononophelo kwaye ubuze ugqirha wakho ukuba awuqinisekanga ukuba lingakanani iyeza ekufuneka ulithathile.

I-Oxcarbazepine inokunceda ukulawula ukubanjwa kwakho kodwa ayizukuyinyanga imeko yakho. Qhubeka uthathe i-oxcarbazepine nokuba uziva uphilile. Sukuyeka ukuthatha i-oxcarbazepine ungakhange uthethe nogqirha wakho, nokuba ngaba uneziphumo ebezingalindelekanga ezinje ngotshintsho olungaqhelekanga kwindlela oziphethe ngayo okanye kwimood. Ukuba ngequbuliso uyeka ukuthatha i-oxcarbazepine, ukubanjwa kwakho kunokuba mandundu. Ugqirha wakho uya kunciphisa umthamo wakho ngokuthe ngcembe.


Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-oxcarbazepine kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

I-Oxcarbazepine ngamanye amaxesha isetyenziselwa ukunyanga isifo esiyi-bipolar disorder (isifo sokudakumba esisifo somntu; isifo esibangela iziqendu zoxinzelelo, iziqendu zovuyo olungaqhelekanga, kunye nezinye iimood ezingaqhelekanga). Thetha nogqirha wakho malunga neengozi zokusebenzisa la mayeza kwimeko yakho.

La mayeza angamiselwa ezinye izinto. Buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-oxcarbazepine:

  • xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-oxcarbazepine, i-carbamazepine (iCarbatrol, i-Epitol, i-Equetro, iTegretol), nawaphi na amanye amayeza, okanye naziphi na izinto ezingasebenziyo kwiipilisi ze-oxcarbazepine, iipilisi ezandisiweyo zokukhululwa, okanye ukumiswa Buza usokhemesti wakho uluhlu lwezinto ezingasebenziyo kwiipilisi ze-oxcarbazepine okanye ukumiswa.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zilandelayo: amiodarone (Cordarone); umgca we-amitriptyline (Elavil); ii-calcium channel blocker ezinje nge-amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Procardia), nimodipine (Nimotop), nisoldipine (Sular) i-verapamil (Calan, Covera, Isoptin, Verelan); chlorpromazine (Thorazine); clomipramine (Anafranil); cyclophosphamide (Cytoxan, Neosar); desmopressin (DDAVP, Minirin, Stimate); diazepam (Valium); umchamo ('iipilisi zamanzi'); indapamide (Natrilix); amanye amayeza okubamba afana ne-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), phenobarbital, phenytoin (Dilantin), kunye ne-valproic acid (Depakene, Depakote); iiproton-pump inhibitors ezifana ne-lansoprazole (Prevacid), omeprazole (Prilosec), kunye ne-pantoprazole (Protonix); theophylline (Theo-Dur); kunye nokukhetha i-serotonin reuptake inhibitors (SSRIs) ezinje nge-citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), kunye sertraline (Zoloft). Amanye amayeza anokusebenzisana ne-oxcarbazepine, ke qiniseka ukuxelela ugqirha wakho kunye nosokhemesti malunga nawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba ukhe unesifo sezintso okanye sesibindi.
  • xelela ugqirha wakho ukuba ungowaseTshayina, Thai, Malaysian, Korean, Indian, okanye Philippines. Umngcipheko wobungozi obusongela ubomi obubizwa ngokuba yiStevens-Johnson syndrome (i-SJS) okanye i-epidermal necrolysis (TEN) iyonyuka kubantu baseAsia abanemfuza. Ukuba ungowaseAsia, ugqirha wakho unokuyalela kuvavanyo ukuze abone ukuba unobungozi bemfuza ngaphambi kokumisela i-oxcarbazepine.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba usebenzisa izinto zokucwangcisa zehomoni, kuya kufuneka uyazi ukuba olu hlobo lolawulo lokuzalwa alunakusebenza kakuhle xa lusetyenziswa ne-oxcarbazepine. Izinto zokucwangcisa zeHormonal akufuneki zisetyenziswe njengeyona ndlela yakho yolawulo lokuzalwa ngelixa usela eli yeza. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Shayela ugqirha wakho ukuba ulahlekile ixesha okanye ucinga ukuba unokukhulelwa ngelixa uthatha i-oxcarbazepine.
  • Kuya kufuneka uyazi ukuba eli yeza linokukwenza wozele okanye ube nesiyezi, lichaphazele indlela ohamba ngayo, okanye linokubangela umbono ophindwe kabini okanye olunye utshintsho lombono. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
  • khumbula ukuba utywala bunokongeza ukozela okubangelwa leli yeza.
  • Kuya kufuneka uyazi ukuba impilo yakho yengqondo inokutshintsha ngeendlela ezingalindelekanga kwaye ungazibulala (ucinga ngokuzenzakalisa okanye ukuzibulala okanye ukucwangcisa okanye ukuzama ukwenza njalo) ngelixa uthatha i-oxcarbazepine kunyango lwesifo sokuwa, ukugula ngengqondo, okanye ezinye iimeko. Inani elincinci labantu abadala kunye nabantwana abaneminyaka emi-5 ubudala nangaphezulu (malunga ne-1 kubantu abangama-500) abathathe ii-anticonvulsants ezinje nge-oxcarbazepine ukunyanga iimeko ezahlukeneyo ngexesha lezifundo zeklinikhi bazibulala ngexesha lonyango lwabo. Abanye baba bantu bakhulise iingcinga zokuzibulala kunye nokuziphatha kwiveki e-1 emva kokuba beqalisile ukuthatha amayeza. Kukho umngcipheko wokuba unokufumana utshintsho kwimpilo yakho yengqondo ukuba uthatha iyeza le-anticonvulsant elinjenge-oxcarbazepine, kodwa kusenokubakho umngcipheko wokuba uya kuba neenguqu kwimpilo yakho yengqondo ukuba imeko yakho ayinyangwa. Wena kunye nogqirha wakho niya kuthatha isigqibo sokuba ngaba ingozi yokuthatha iyeza le-anticonvulsant inkulu kuneengozi zokungawasebenzisi amayeza. Wena, usapho lwakho, okanye umntu omkhathalelayo kufuneka ubize ugqirha wakho ngoko nangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: uloyiko; ukuphazamiseka okanye ukungazinzi; okutsha okanye ukuhla kokucaphuka, uxinzelelo, okanye uxinzelelo; ukwenza izinto eziyingozi; ubunzima bokuwa okanye ukulala; ndlongondlongo, umsindo okanye ubundlobongela; i-mania (i-frenzied, i-mood engaqhelekanga) ukuthetha okanye ukucinga ngokufuna ukuzenzakalisa okanye ukuzibulala; Ukurhoxa kubahlobo nakusapho; ukuxakeka kukufa nokufa; ukuphisa ngezinto ezixabisekileyo; okanye naluphi na olunye utshintsho olungaqhelekanga kwindlela oziphethe ngayo okanye kwimood. Qiniseka ukuba usapho lwakho okanye umntu okhathalelayo uyazi ukuba zeziphi iimpawu ezinokuba nobuzaza ukuze babize ugqirha ukuba awukwazi ukuzifunela unyango ngokwakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.


Ngaphambi kokuba uqale unyango lwakho, thetha nogqirha wakho malunga nento ekufuneka uyenzile ukuba ngempazamo uphose idosi. Qiniseka ukuba ubuza ugqirha wakho ukuba uza kulinda ixesha elingakanani phakathi kokuthatha idosi ephosiweyo kunye nokuthatha idosi yakho elandelayo ye-oxcarbazepine. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Oxcarbazepine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • ngokukhawuleza, ukuphindaphinda ukunyakaza kwamehlo ongenakukulawula
  • urhudo
  • ukuqhina
  • isilungulela
  • isisu esibuhlungu
  • isicaphucaphu
  • ukugabha
  • Ukuphelelwa ngumdla wokutya
  • utshintsho kwindlela ekunambitheka ngayo ukutya
  • umlomo owomileyo
  • unxano
  • ukutyeba kwakho
  • intloko ebuhlungu
  • ukushukuma kwelungu lomzimba ongenakulilawula; ubunzima bokulungelelanisa iintshukumo; iwa phantsi
  • ukunyakaza okucothayo okanye iingcinga; ukulibala, ubunzima bokugxila, kunye neengxaki zokuthetha
  • umqolo, ingalo, okanye umlenze obuhlungu
  • ubuthathaka bemisipha okanye ukuqina ngokukhawuleza
  • ukwanda kokubila
  • ukudumba, ukuba bomvu, ukurhawuzelela, ukutshisa, okanye ukurhawuzelela kwelungu lobufazi, ukuphuma okumhlophe kwilungu lobufazi

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko:

  • irhashalala; imihlathi ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha, okanye imilenze esezantsi: okanye ubunzima bokuginya nokuphefumla
  • isicaphucaphu, intloko ebuhlungu, ukunqongophala kwamandla, ukudideka, okanye ukuxhuzula okuhlala ixesha elide okanye ukwenzeka rhoqo kunakuqala
  • ukuxobuka, ukudubula, okanye ukuchitha ulusu
  • irhashalala; imihlathi izilonda emlonyeni okanye ngeenxa zonke emehlweni; ifiva; ukudinwa kakhulu; iintlungu zesifuba; buthathaka kwezihlunu okanye iintlungu; ukudumba kobuso, intamo, i-groin, okanye indawo yangaphantsi; ubumthubi besikhumba okanye amehlo; ukopha okungaqhelekanga okanye ukugruzuka; enegazi, enamafu, inyukile, iyancipha, okanye uchama kabuhlungu
  • umqala obuhlungu, ukukhohlela, ukugodola kunye neminye imiqondiso yosulelo

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifikeleleki kwaye alibonwa ngabantwana. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Gcina iipilisi ezikhutshiweyo kude nokukhanya. Lahla nakuphi na ukumiswa okungasetyenziswanga okungasetyenziswanga kwiiveki ezisi-7 emva kokuba ibhotile ivulwe kuqala.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yakho kwi-oxcarbazepine.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-oxcarbazepine.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • I-Oxtellar XR®
  • Trileptal®
Ukuhlaziywa kokugqibela-04/15/2019

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