Umbhali: Clyde Lopez
Umhla Wokudalwa: 19 Eyekhala 2021
Hlaziya Umhla: 17 Eyenkanga 2024
Anonim
Aldosterone Antagonists-  Eplerenone
Ividiyo: Aldosterone Antagonists- Eplerenone

Umxholo

I-Eplerenone isetyenziswa yodwa okanye idityaniswe namanye amayeza ukunyanga uxinzelelo lwegazi. I-Eplerenone ikwiklasi yamayeza abizwa ngokuba ngabachasi be-mineralocorticoid receptor. Isebenza ngokuthintela isenzo se-aldosterone, into yendalo emzimbeni ophakamisa uxinzelelo lwegazi.

Uxinzelelo lwegazi oluphezulu yimeko eqhelekileyo kwaye xa lunganyangwa, lunokubangela ukonakala kwengqondo, intliziyo, imithambo yegazi, izintso namanye amalungu omzimba. Ukonakala kula malungu kunokubangela isifo sentliziyo, isifo sentliziyo, ukusilela kwentliziyo, ukubetha, ukusilela kwezintso, ukungaboni kakuhle, kunye nezinye iingxaki. Ukongeza ekuthatheni amayeza, ukwenza utshintsho kwindlela yokuphila kuya kunceda ukulawula uxinzelelo lwegazi. Olu tshintsho lubandakanya ukutya ukutya okunamafutha amancinci kunye netyuwa, ukugcina ubunzima obunempilo, ukusebenzisa ubuncinci imizuzu engama-30 ubuninzi beentsuku, ukungatshayi, kunye nokusebenzisa utywala ngokumodareyitha.

I-Eplerenone iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye okanye kabini ngemini, kunye okanye ngaphandle kokutya. Ukukunceda ukhumbule ukuthatha i-eplerenone, thatha ixesha elifanayo (ii) mihla le. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-eplerenone ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.


Ugqirha wakho unokukuqala kwidosi esezantsi ye-eplerenone kwaye wandise idosi yakho emva kweeveki ezi-4.

I-Eplerenone ilawula uxinzelelo lwegazi oluphezulu kodwa ayiyinyangi. Ingathatha iiveki ezi-4 okanye ngaphezulu ngaphambi kokuba uve isibonelelo se-eplerenone. Qhubeka uthatha i-eplerenone nokuba uziva uphilile. Ungayeki ukuthatha i-eplerenone ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-eplerenone,

  • xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-eplerenone, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-eplerenone. Buza usokhemesti wakho uluhlu lwezithako.
  • sukuthatha i-eplerenone ukuba uthatha i-amiloride (Midamor), amiloride kunye nehydrochlorothiazide, itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), izongezo zepotassium, spironolactone (Aldactone), spironolactone kunye nehydrochlorothiazide (Aldactazide), Aldactazide), triamterene kunye nehydrochlorothiazide (Dyazide, Maxzide).
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini kunye nezongezelelo zesondlo ozithathayo. Qiniseka ukuba ukhankanya oku kulandelayo: i-angiotensin eguqula i-enzyme (ACE) inhibitors enjenge benazepril (Lotensin, eLotrel), captopril (Capoten), enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (in Prinzide, in Zestoretic), kunye nequinapril (Accupril, in Accuretic, in Quinaretic); ii-angiotensin II receptor antagonists ezinje nge-azilsartan (Edarbi, e-Edarbyclor), candesartan (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, eAvalide), losartan (Cozaar, e-Hyzaar), olmesartan (Benicar, , kwiBenicar HCT), telmisartan (Micardis, eMicardis HCT, eTwynsta), nasevalsartan (Diovan, eDiovan HCT, Exforge); i-aspirin kunye nezinye iziyobisi ezichasayo (i-NSAIDs) ezifana ne-ibuprofen (Advil, Motrin) kunye ne-naproxen (Aleve, Naprosyn); cimetidine (iTagamet); i-clarithromycin (i-Biaxin); idanazol; delavirdine (Umshicileli); diltiazem (Cardizem, Dilacor, Tiazac, nabanye); i-erythromycin (i-EES, i-E-Mycin, i-Erythrocin); i-fluconazole (iDiflucan); fluoxetine (Prozac, Sarafem, Selfemra); i-fluvoxamine (iLuvox); I-HIV protease inhibitors efana ne-indinavir (Crixivan), ritonavir (Norvir, eKaletra), kunye ne-saquinavir (i-Invirase); isoniazid (Laniazid, eRifamate, Rifater); lithium (Lithobid); iMetronidazole (Flagyl); nefazodone; i-verapamil (Calan, Covera, Verelan, eTarka); kunye ne-zafirlukast (eyiyo). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
  • xelela ugqirha wakho ukuba wakhe wanamaqondo aphezulu egazi potassium, isifo seswekile, igawuthi, okanye isibindi okanye isifo sezintso.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-eplerenone, tsalela ugqirha wakho.

Thetha nogqirha wakho malunga nokusela ijusi yegrapefruit ngelixa uthatha eli yeza.


Sukusebenzisa iityuwa ezibambe i-potassium ngelixa uthatha i-eplerenone. Ukuba ugqirha wakho ukumisela ukutya okunetyuwa encinci okanye ukutya okunesodiyamu encinci, landela le miyalelo ngononophelo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Eplerenone inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • intloko ebuhlungu
  • isiyezi
  • urhudo
  • isisu esibuhlungu
  • ukukhohlela
  • ukudinwa kakhulu
  • Iimpawu ezinjengomkhuhlane
  • ukwandiswa kwebele okanye ukuthamba
  • ukopha ngokungaqhelekanga kwilungu lobufazi

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo, tsalela ugqirha ngokukhawuleza:

  • iintlungu zesifuba
  • ukurhawuzelela iingalo nemilenze
  • ukulahleka kwethoni yezihlunu
  • ubuthathaka okanye ubunzima emilenzeni
  • ukudideka
  • ukunqongophala kwamandla
  • ibanda, isikhumba esingwevu
  • ukubetha kwentliziyo ngokungaqhelekanga

I-Eplerenone inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.


Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

  • isiqaqa
  • isiyezi
  • ukungaboni kakuhle
  • isisu esimoshakele
  • ukurhawuzelela iingalo nemilenze
  • ukulahleka kwethoni yezihlunu
  • ubuthathaka okanye ubunzima emilenzeni
  • ukudideka
  • ukunqongophala kwamandla
  • ibanda, isikhumba esingwevu
  • ukubetha kwentliziyo okungaqhelekanga okanye okucothayo

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kujonga uxinzelelo lwegazi rhoqo kwaye ayalele iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-eplerenone.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • Inspra®
Ukuhlaziywa kokugqibela-02/15/2016

Amanqaku Anomdla

Isifo sikaParkinson

Isifo sikaParkinson

I ifo ikaParkin on (PD) luhlobo lokuhamba okungahambi kakuhle. Kwenzeka xa ii eli zemithambo-luvo kwingqondo zingaveli i ngokwaneleyo imichiza yobuchopho ebizwa ngokuba yi-dopamine. Ngamanye amaxe ha ...
IBacillus Coagulans

IBacillus Coagulans

Bacillu coagulan luhlobo lweent holongwane. I etyenzi wa ngokufanayo ne-lactobacillu kunye nezinye iiprobiotic njengeebhaktheriya "eziluncedo". Abantu bathatha i-Bacillu coagulan ye ifo e in...