Fosamprenavir
Umxholo
- Ngaphambi kokuba uthathe i-fosamprenavir,
- I-Fosamprenavir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana enye yezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo.
IFosamprenavir isetyenziswa kunye namanye amayeza ukunyanga intsholongwane kaGawulayo. UFosamprenavir ukwiklasi yamayeza abizwa ngokuba zii-protease inhibitors. Isebenza ngokunciphisa inani le-HIV egazini.Nangona i-fosamprenavir ingayinyangi i-HIV, inokuwanciphisa amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezinzulu okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokudlulisela intsholongwane kagawulayo kwabanye abantu.
IFosamprenavir iza njengecwecwe kunye nokumiswa (okungamanzi) ukuthatha ngomlomo. Ihlala ithathwa kanye okanye kabini ngemini. Amacwecwe angathathwa kunye okanye ngaphandle kokutya. Kwizigulana ubuneminyaka eli-18 ubuncinci, ukumiswa kufuneka kuthathwe ngaphandle kokutya. Kwizigulana ezingaphantsi kweminyaka eli-18 ubudala, ukumiswa kufuneka kuthathwe kunye nokutya. Ukukunceda ukhumbule ukuthatha i-fosamprenavir, yithathe malunga namaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-fosamprenavir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.
Ukuba uthatha ukunqunyanyiswa, yigungqise kakuhle ngaphambi kokuba uyisebenzise ukuxuba amayeza ngokulinganayo.
Ukuba uhlanza ngaphantsi kwemizuzu engama-30 emva kokuba uthathe i-fosamprenavir, kuya kufuneka uthathe enye idosi epheleleyo yefosamprenavir.
IFosamprenavir ilawula usulelo lwe-HIV kodwa ayilunyangi. Qhubeka nokuthatha i-fosamprenavir nokuba uziva uphilile. Sukuyeka ukuthatha i-fosamprenavir ngaphandle kokuthetha nogqirha wakho. Ukuba uphosa idosi okanye uyeke ukuthatha i-fosamprenavir, imeko yakho kunokuba nzima ukuyinyanga.
Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.
Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.
Ngaphambi kokuba uthathe i-fosamprenavir,
- xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-fosamprenavir, i-amprenavir (iAgenerase; ayisafumaneki e-U.S), amayeza e-sulfa, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-fosamprenavir okanye ukumiswa. Buza usokhemesti wakho uluhlu lwezithako.
- xelela ugqirha wakho ukuba uthatha i-alfuzosin (Uroxatral); i-cisapride (Propulsid) (ayifumaneki e-US); delavirdine (Umshicileli); amayeza e-ergot anjenge-dihydroergotamine (i-DHE 45, iMigranal), i-ergoloid mesylates (iHydergine), i-ergonovine, i-ergotamine (i-Ergomar, eCafergot, eMigergot), kunye ne-methylergonovine (Methergine); lomitapide (Juxtapid); I-lovastatin (Altoprev); midazolam (iVesi); ipimozide (Orap); irifampin (Rifadin, Rimactane, eRifater, eRifamate); sildenafil (kuphela uphawu lweRevatio olusetyenziselwa isifo semiphunga); isimvastatin (iZocor, eVytorin); I-wort yaseSt. okanye i-triazolam (Halcion). Ugqirha wakho uya kukuxelela ukuba ungathathi i-fosamprenavir ukuba uthatha elinye okanye ngaphezulu kula mayeza.
- musa ukuthatha i-flecainide, i-lurasidone (iLatuda), okanye ipropafenone (iRhythmol) ukuba nithatha i-fosamprenavir kunye ne-ritonavir (i-Norvir) kunye.
- xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini kunye nezongezelelo zesondlo ozithathayo. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin, Jantoven); antidepressants ezifana amitriptyline, imipramine (Surmontil), paroxetine (Brisdelle, Paxil, Pexeva), kunye trazodone; atorvastatin (Lipitor, kwiCaduet); ii-antacids eziqukethe i-aluminium kunye ne-magnesium (Maalox, ezinye); i-benzodiazepines efana ne-alprazolam (Xanax), i-clorazepate (iGen-Xene, iTranxene), i-diazepam (iDiastat, iValium) kunye ne-flurazepam; i-bosentan (iTracleer); ii-calcium channel blocker ezinje nge-amlodipine (Norvasc, e-Exforge, abanye), diltiazem (Cardizem, Cartia, Tiazac, abanye), felodipine, isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab CR, Procardia), nimodipine (Nymalize), nisoldipine (Sular), kunye neverapamil (Calan, Covera, Verelan, eTarka); icolchicine (iiColcrys, iMitigare); dasatinib (Sprycel); dexamethasone; i-everolimus (i-Afinitor); fentanyl (iDuragesic); i-fluticasone (iFlonase, iFlovent, eAdvair); i-histamine H2-receptor blockers efana ne-cimetidine, i-famotidine (i-Pepcid), i-nizatidine (i-Axid), kunye ne-ranitidine (iZantac); ibrutinib (Imbruvica); itraconazole (Onmel, Sporanox); amayeza okubetha kwentliziyo ngokungaqhelekanga njenge-amiodarone (Nexterone, Pacerone), disopyramide (Norpace), lidocaine (Lidoderm; eXylocaine kunye ne-Epinephrine), kunye nequinidine (eNuedexta); ketoconazole (Nizoral); I-nilotinib (iTasigna); amayeza okubanjwa afana ne-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, abanye), phenobarbital, kunye ne phenytoin (Dilantin, Phenytek); amayeza athintela amajoni omzimba anje ngecyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), okanye tacrolimus (Astagraf XL, Prograf); imethadone (iDolophine, iMethadose); amanye amayeza okunyanga i-HIV kubandakanya i-dolutegravir (Tivicay), efavirenz (Sustiva, e-Atripla), indinavir (Crixivan), lopinavir (Kaletra), maraviroc (Selzentry), nelfinavir (Viracept), nevirapine (Viramune), raltegravir (Isentirivir (ENorvir, eKaletra, eViekira Pak), kunye nase-saquinavir (i-Invirase); amayeza athile okunyanga intsholongwane ye-hepatitis C kubandakanya i-boceprevir (ayisafumaneki e-U.S. UVictrelis), paritaprevir (eViekira XR), kunye ne-simeprevir (engasekhoyo e-U.S. Olysio); ezithile ze-phosphodiesterase inhibitors (PDE-5 inhibitors) ezisetyenziselwa ukungasebenzi kakuhle kwe-erectile njenge-sildenafil (Viagra), tadalafil (Cialis), kunye ne-vardenafil (Levitra); iquetiapine (iSeroquel); irifabutin (Mycobutin); isalmeterol (iSerevent, eAdvair); tadalafil (Adcirca); kunye nevinblastine. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-fosamprenavir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
- xelela ugqirha wakho ukuba ukhe unesifo seswekile, ihemophilia (isifo apho igazi lingagugi ngesiqhelo), i-cholesterol ephezulu okanye i-triglycerides, okanye isifo sezintso okanye sesibindi, kubandakanya i-hepatitis B okanye i-C.
- xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwa ngelixa uthatha i-fosamprenavir, tsalela ugqirha wakho. Akufanelanga ukuncancisa xa wosulelwe yi-HIV okanye uthatha i-fosamprenavir.
- ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-fosamprenavir.
- Kuya kufuneka uyazi ukuba i-fosamprenavir inokunciphisa ukusebenza kwezicwangcisi zomlomo (iipilisi zolawulo lokuzalwa). Thetha nogqirha wakho ngezinye iindlela zokuthintela ukukhulelwa ngelixa uthatha eli yeza.
- Kuya kufuneka uyazi ukuba amanqatha omzimba wakho anokunyuka okanye ahambele kwiindawo ezahlukeneyo zomzimba wakho ezinje ngamabele akho kunye nomqolo wangasentla.
- Kuya kufuneka uyazi ukuba unokufumana i-hyperglycemia (inyuka kwiswekile esegazini lakho) ngelixa uthatha eli yeza, nokuba awukabinaso isifo seswekile. Xelela ugqirha wakho kwangoko ukuba unayo nayiphi na kwezi mpawu zilandelayo ngelixa uthatha i-fosamprenavir: ukunxanwa okugqithisileyo, ukuchama rhoqo, ukulamba kakhulu, ukungaboni kakuhle, okanye ubuthathaka. Kubaluleke kakhulu ukubiza ugqirha wakho nje ukuba ube nazo naziphi na ezi mpawu, kuba iswekile ephezulu yegazi enganyangekiyo inokubangela imeko embi ebizwa ngokuba yi ketoacidosis. I-Ketoacidosis inokuba sengozini yobomi ukuba ayinyangwa kwangoko. Iimpawu zeketoacidosis zibandakanya: umlomo owomileyo, isicaphucaphu kunye nokugabha, ukuphefumla kancinci, umphefumlo onuka iziqhamo, kunye nokwehla kwengqondo.
- Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho. Oku kunokubangela ukuba ube neempawu zolu sulelo. Ukuba uneempawu ezintsha okanye eziba mandundu nangaliphi na ixesha kunyango lwakho ngefosamprenavir, qiniseka ukuxelela ugqirha wakho.
Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.
Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.
I-Fosamprenavir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
- urhudo
- isicaphucaphu
- ukugabha
- intloko ebuhlungu
- ukudinwa kakhulu
Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana enye yezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo.
- irhashalala
- ukurhawuzelela
- imihlathi, iblisters, okanye isikhumba esixobukayo
- ubunzima bokuphefumla okanye ukugwinya
- ukudumba kobuso bakho, amehlo, imilebe, ulwimi, okanye umqala
- umqala obuhlungu, umkhuhlane, Ukugodola, ukukhohlela, kunye neminye imiqondiso yosulelo
- umqolo okanye iintlungu ezisecaleni
- igazi kumchamo
- intlungu xa uchama
I-Fosamprenavir inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.
Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).
Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Ukunqunyanyiswa kungagcinwa nakwifriji, kodwa musa ukuyiqanda.
Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org
Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.
Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.
Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zelebhu ngaphambi kwaye ngexesha lonyango lwakho ukuze uqiniseke ukuba kukhuselekile kuwe ukuba uthathe i-fosamprenavir kwaye ujonge impendulo yomzimba wakho kwi-fosamprenavir.
Musa ukuphelelwa ngamayeza. Xa unikezelo lwakho lwefosamprenavir luqala ukuba phantsi, fumana okungakumbi kugqirha wakho okanye kwikhemesti.
Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.
Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.
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