Umbhali: Gregory Harris
Umhla Wokudalwa: 16 Utshazimpuzi 2021
Hlaziya Umhla: 1 Eyenkanga 2024
Anonim
Inaliti yeDarbepoetin Alfa - Iyeza
Inaliti yeDarbepoetin Alfa - Iyeza

Umxholo

Zonke izigulana:

Sebenzisa inaliti ye-darbepoetin alfa yonyusa umngcipheko wokuba amahlwili egazi aya kungena okanye ahambe emilenzeni, emiphungeni, okanye kwingqondo. Xelela ugqirha wakho ukuba ukhe unesifo sentliziyo kwaye wakha wahlaselwa sistroke. Biza ugqirha wakho kwangoko okanye ufumane uncedo lonyango olungxamisekileyo ukuba ufumana naziphi na kwezi mpawu zilandelayo: iintlungu, ukuthamba, ukuba bomvu, ukufudumala, kunye / okanye ukudumba emilenzeni; ukuphola okanye ukuphaphatheka engalweni okanye emlenzeni; ukuqhawukelwa ngumphefumlo; ukukhwehlela okungayi kuhamba okanye okuzisa igazi; iintlungu zesifuba; Ingxaki ekhawulezileyo yokuthetha okanye intetho eqondayo; ukudideka ngesiquphe; ubuthathaka ngequbuliso okanye ukuba ndindisholo kwengalo okanye umlenze (ngakumbi kwicala elinye lomzimba) okanye kobuso; ingxaki yokuhamba ngesiquphe, isiyezi, okanye ilahleko eseleyo okanye yokulungelelanisa; okanye isiqaqa. Ukuba uphathwa nge-hemodialysis (unyango lokususa inkunkuma egazini xa izintso zingasebenzi), iqokobhe legazi lingenza ufikelelo lwakho lwe-vascular (indawo apho i-hemodialysis tubing idibanisa nomzimba wakho). Tshela ugqirha wakho ukuba ukufikelela kwakho kwe-vascular kuyeka ukusebenza njengesiqhelo.


Ugqirha wakho uza kuyilungisa idosi yakho yenaliti ye-darbepoetin alfa ukuze inqanaba lakho le-hemoglobin (isixa seprotein efumaneka kwiiseli ezibomvu zegazi) liphezulu ngokwaneleyo ukuba awudingi kutofelwa iiseli ezibomvu zegazi (ukuhanjiswa kweeseli ezibomvu zegazi lomntu komnye Umzimba womntu ukunyanga i-anemia). Ukuba ufumana i-albepoetin alfa eyaneleyo yokwandisa i-hemoglobin yakho ukuya kwinqanaba eliqhelekileyo okanye elikufutshane, kukho umngcipheko omkhulu wokuba uya kuba nesifo sokuhlaselwa yintlungu okanye ube neengxaki ezinzulu okanye ezisongela ubomi ezibandakanya ukuhlaselwa yintliziyo kunye nokuhluleka kwentliziyo. Biza ugqirha wakho kwangoko okanye ufumane uncedo lonyango olungxamisekileyo ukuba ufumana naziphi na kwezi mpawu zilandelayo: iintlungu esifubeni, uxinzelelo lokucinezela, okanye ukuqina; ukuqhawukelwa ngumphefumlo; isicaphucaphu, iintloko, ukubila, kunye neminye imiqondiso yokuqala yesifo sentliziyo; ukungonwabi okanye iintlungu ezingalweni, egxalabeni, entanyeni, emhlathini, okanye emqolo; okanye ukudumba kwezandla, iinyawo, okanye amaqatha.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-darbepoetin alfa injection. Ugqirha wakho unokunciphisa idosi okanye akuxelele ukuba uyeke ukusebenzisa inaliti ye-darbepoetin alfa kangangexesha elithile ukuba iimvavanyo zibonisa ukuba usemngciphekweni omkhulu wokufumana iziphumo ebezingalindelekanga ezimandundu. Landela izikhokelo zikagqirha wakho ngononophelo.


Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-darbepoetin alfa kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nomngcipheko wokusebenzisa inaliti ye-darbepoetin alfa.

Izigulana ezinomhlaza:

Kwizifundo zeklinikhi, abantu abanomhlaza othile abafumene inaliti ye-darbepoetin alfa basweleke msinya okanye bafumana ukukhula kwethumba, ukubuya komhlaza wabo, okanye umhlaza osasazeke msinyane kunabantu abangakhange bafumane iyeza. Ukuba unomdlavuza, kuya kufuneka ufumane elona thamo lisezantsi linokubakho lenaliti ye-darbepoetin alfa. Kuya kufuneka ufumane inaliti ye-darbepoetin alfa ukunyanga i-anemia ebangelwa yi-chemotherapy ukuba i-chemotherapy yakho kulindeleke ukuba iqhubeke ubuncinci iinyanga ezi-2 emva kokuba uqale unyango ngenaliti ye-darbepoetin alfa kwaye ukuba akukho thuba liphezulu lokuba umhlaza wakho uza kuphiliswa. Unyango ngenaliti ye-darbepoetin alfa kufuneka imiswe xa ikhosi yakho ye-chemotherapy iphela.


Inkqubo ebizwa ngokuba yiNkqubo ye-ESA APPRISE Oncology isetelwe ukunciphisa umngcipheko wokusebenzisa inaliti ye-darbepoetin alfa ukunyanga i-anemia ebangelwa yi-chemotherapy. Ugqirha wakho kuya kufuneka agqibe uqeqesho kwaye abhalise kule nkqubo ngaphambi kokuba ufumane inaliti ye-darbepoetin alfa. Njengenxalenye yenkqubo, uyakufumana ulwazi olubhaliweyo malunga nemingcipheko yokusebenzisa inaliti ye-darbepoetin alfa kwaye kuyakufuneka utyikitye ifomu ngaphambi kokuba ufumane iyeza ukubonisa ukuba ugqirha wakho uthethile ngomngcipheko we-darbepoetin alfa injection nawe. Ugqirha wakho uya kukunika ulwazi oluthe kratya malunga nenkqubo kwaye uya kuphendula nayiphi na imibuzo onayo malunga nenkqubo kunye nonyango lwakho ngenaliti ye-darbepoetin alfa.

Inaliti ye-Darbepoetin alfa isetyenziselwa ukunyanga i-anemia (inani elisezantsi kuneliqhelekileyo leeseli ezibomvu zegazi) kubantu abanesifo sezintso esinganyangekiyo (imeko apho izintso zithi chu ziyeke ukusebenza ixesha elide). Inaliti yeDarbepoetin alfa ikwasetyenziselwa ukunyanga i-anemia ebangelwa yichemotherapy kubantu abaneentlobo ezithile zomhlaza. I-Darbepoetin alfa ayinakusetyenziswa endaweni yegazi elibomvu ukunyanga i-anemia kwaye ayiboniswanga ukuphucula ukudinwa okanye impilo-ntle enokubangelwa yi-anemia. UDarbepoetin alfa ukwiklasi yamayeza abizwa ngokuba zii-erythropoiesis-stimulating agents (ESAs). Isebenza ngokubangela umongo wethambo (izicwili ezithambileyo ngaphakathi kwamathambo apho igazi lenziwa khona) ukwenza iiseli ezibomvu zegazi ngakumbi.

Inaliti yeDarbepoetin alfa iza njengesisombululo (ulwelo) ukujova (ngaphantsi nje kwesikhumba) okanye ngaphakathi ngaphakathi (emthanjeni). Ihlala itofwe kanye kwiiveki ezi-1 ukuya kwezi-4. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa inaliti ye-darbepoetin alfa ngqo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Ugqirha wakho uza kukuqala ngedosi esezantsi yenaliti ye-darbepoetin alfa kwaye uhlengahlengise idosi yakho ngokuxhomekeke kwiziphumo zakho zebhu kunye nendlela oziva ngayo. Ugqirha wakho unokukuxelela ukuba uyeke ukusebenzisa inaliti ye-darbepoetin alfa okwexeshana. Landela le miyalelo ngononophelo.

Inaliti yeDarbepoetin alfa iyakunceda ukulawula i-anemia kuphela ukuba uqhubeka nokuyisebenzisa. Ingathatha iiveki ezi-2 ukuya kwezi-6 okanye ngaphezulu ngaphambi kokuba uve isibonelelo esipheleleyo senaliti ye-darbepoetin alfa. Qhubeka usebenzise inaliti ye-darbepoetin alfa nokuba uziva uphilile. Sukuyeka ukusebenzisa inaliti ye-darbepoetin alfa ngaphandle kokuthetha nogqirha wakho.

Inaliti yeDarbepoetin alfa inokunikwa ngugqirha okanye ngumongikazi, okanye ugqirha wakho angathatha isigqibo sokuba unokuzifaka ngokwakho i-darbepoetin alfa, okanye unokuba nomhlobo okanye isizalwane esinika inaliti. Wena kunye nomntu oza kunika inaliti kufuneka ufunde ulwazi lomenzi wesigulana esiza nenaliti ye-darbepoetin alfa ngaphambi kokuba uyisebenzise okokuqala ekhaya. Buza ugqirha wakho akubonise okanye umntu oza kufaka inaliti iyeza ukuba ungalitofa njani.

Inaliti ye-Darbepoetin alfa ingena kwiisirinji ezikhethiweyo nakwiibhotile eziza kusetyenziswa ngeesirinji ezilahlwayo. Ukuba usebenzisa iibhotile zedalbepoetin alfa injection, ugqirha wakho okanye usokhemesti uya kukuxelela ukuba loluphi uhlobo lwesirinji ekufuneka uyisebenzisile. Sukusebenzisa naluphi na uhlobo lwesirinji kuba awunakufumana inani elifanelekileyo lamayeza.

Sukushukumisa idarbepoetin alfa inaliti. Ukuba uyashukumisa i-darbepoetin alfa inaliti inokubonakala ngathi igwebu kwaye akufuneki isetyenziswe.

Soloko utofa inaliti ye-darbepoetin alfa kwisirinji yayo. Musa ukungxengxeza ngayo nayiphi na into engamanzi kwaye ungayidibanisi namanye amayeza.

Ungayifaka inaliti yedarbepoetin alfa naphina kwindawo engaphandle yeengalo zakho ezingaphezulu, isisu sakho ngaphandle kwendawo ye-intshi ezi-2 (isentimitha ezi-5) ejikeleze inkaba yakho (iqhosha lesisu), umphambili wamathanga akho aphakathi, kunye neendawo ezingaphandle ezingaphezulu iimpundu zakho. Khetha indawo entsha ngalo lonke ixesha ufaka i-darbepoetin alfa. Sukujova i-darbepoetin alfa kwindawo ethambileyo, ebomvu, etyumkileyo, okanye elukhuni, okanye enezikrelemnqa okanye amanqaku wolule.

Ukuba uphathwa nge-dialysis (unyango lokususa inkunkuma egazini xa izintso zingasebenzi), ugqirha wakho angakuxelela ukuba utofe iyeza kwizibuko lakho lokungena (indawo apho i-dialysis tubing idityaniswe nomzimba wakho). Buza ugqirha wakho ukuba unemibuzo malunga nokuba ungalifaka njani iyeza lakho.

Ngalo lonke ixesha jonga kwisisombululo senaliti yedarbepoetin alfa ngaphambi kokuyifaka. Qiniseka ukuba isirinji okanye igutyana ekhethiweyo ibhalwe igama elichanekileyo kunye namandla eyeza kunye nomhla wokuphelelwa kwayo ongadlulanga. Ukuba usebenzisa ibhotile, jonga uqiniseke ukuba inekepusi enemibala, kwaye ukuba usebenzisa isirinji ekhethiweyo, jonga ukuba inaliti igqunyiwe ngesigqubuthelo esingwevu nokuba umkhono weplastiki otyheli awukhange utsalwe ngaphezulu kwenaliti. . Jonga ukuba isisombululo sicacile kwaye asinambala kwaye asiqulathanga amaqhuma, iiflakes, okanye amasuntswana. Ukuba kukho naziphi na iingxaki amayeza akho, tsalela usokhemisti wakho kwaye musa ukujova.

Sukusebenzisa iisirinji ezikhethiweyo, iisirinji ezilahlwayo, okanye iibhotile zedalbepoetin alfa inaliti ngaphezu kwesinye. Lahla iisirinji ezisetyenzisiweyo kwisitya esinganyangekiyo. Buza ugqirha wakho okanye usokhemesti ngendlela yokusilahla isikhongozeli esinganyangekiyo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti ye-darbepoetin alfa,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nedarbepoetin alfa, epoetin alfa (Epogen, Procrit), nawaphi na amanye amayeza, okanye nasiphi na isithako senaliti ye-darbepoetin alfa.Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako. Ukuba uza kusebenzisa iisirinji ezizalisiweyo, xelela ugqirha wakho ukuba wena okanye umntu oza kungenza iyeza lale ngxaki akungebi nomzimba uthambile.
  • xelela ugqirha wakho ukuba unayo okanye unayo uxinzelelo oluphezulu lwegazi, kwaye ukuba ukhe waba ne-aplasia ebomvu engaxutywanga (i-PRCA; uhlobo lwe-anemia ebukhali enokuthi ivele emva konyango nge-ESA enje ngenaliti ye-darbepoetin alfa okanye inaliti ye-epoetin alfa). Ugqirha wakho unokukuxelela ukuba ungasebenzisi inaliti ye-darbepoetin alfa.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba ukhe waxhuzula okanye wakha waxhuzula. Ukuba usebenzisa inalbepoetin alfa inaliti ukunyanga i-anemia ebangelwa sisifo sezintso esinganyangekiyo, xelela ugqirha wakho ukuba unawo okanye wakhe wanomhlaza.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa usebenzisa inaliti ye-darbepoetin alfa, tsalela ugqirha wakho.
  • Phambi kokuba utyandwe, kubandakanya utyando lwamazinyo, xelela ugqirha wakho okanye ugqirha wamazinyo ukuba unyangwa ngenaliti ye-darbepoetin alfa. Kubaluleke ngakumbi ukuxelela ugqirha wakho ukuba usebenzisa inaliti ye-darbepoetin alfa ukuba une-coronary artery bypass graft (CABG) yoqhaqho okanye yotyando lokunyanga ingxaki yethambo. Ugqirha wakho unokukunika i-anticoagulant ('igazi elincinci') ukunqanda amahlwili ekubumbeni ngexesha lotyando.

Ugqirha wakho unokuyalela ukutya okhethekileyo ukukunceda ukulawula uxinzelelo lwegazi kunye nokunceda ukunyusa amanqanaba akho e-iron ukuze inaliti ye-darbepoetin alfa isebenze kangangoko. Landela le miyalelo ngononophelo kwaye ubuze ugqirha wakho okanye ugqirha wezondlo ukuba unayo nayiphi na imibuzo.

Tsalela umnxeba ugqirha wakho akubuze ukuba wenzeni ukuba uphoswa yidosi yenaliti ye-darbepoetin alfa. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo.

Inaliti yeDarbepoetin alfa inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • ukukhohlela
  • isisu esibuhlungu
  • ububomvu, ukudumba, ukugruzuka, ukurhawuzelela, okanye iqhuma kwindawo apho utofa khona i-darbepoetin alfa

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

  • irhashalala
  • ukurhawuzelela
  • ubunzima bokuphefumla okanye ukugwinya
  • ukuvutha
  • ukudinwa
  • ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
  • ukubetha ngokukhawuleza
  • ukudinwa kakhulu
  • ukunqongophala kwamandla
  • isiyezi
  • isiqaqa
  • ulusu oluthuthu

Inaliti yeDarbepoetin alfa inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga okanye awuziva kakuhle ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina la mayeza ebhokisini engenile, evaliwe ngokuqinileyo, kwaye kude nokufikelela kwabantwana. Nje ukuba ibhotile okanye isirinji ekhethiweyo ikhutshwe ebhokisini yayo, yigcine ikhuselwe ukuyikhusela ekukhanyeni kwegumbi de kube kunikwe idosi. Gcina inaliti ye-darbepoetin alfa efrijini, kodwa ungayenzi ngumkhenkce. Lahla nawaphi na amayeza afriziwe.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho. Ugqirha wakho uza kubeka esweni uxinzelelo lwegazi rhoqo ngexesha lonyango lwakho ngenaliti ye-darbepoetin alfa.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba usebenzisa inaliti ye-darbepoetin alfa.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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Ukuhlaziywa kokugqibela-04/15/2016

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