I-Estrogen kunye neProgestin (Izicwangcisi zokuthintela ukukhulelwa kwendoda)

Umxholo

• Ngaphambi kokusebenzisa i-estrogen kunye neprogestin iringi yelungu lobufazi,
• Iringi yangaphantsi ye-Estrogen kunye neprogestin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo biza ugqirha ngokukhawuleza:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

Ukutshaya icuba kukonyusa umngcipheko weziphumo ebezingalindelekanga ezivela kwi-estrogen kunye ne-progestin iringi yelungu lobufazi, kubandakanya isifo sentliziyo, amahlwili egazi kunye nemivumbo. Lo mngcipheko uphezulu kwabasetyhini abangaphezulu kweminyaka engama-35 ubudala kunye nabantu abatshayayo kakhulu (i-15 okanye iisigarethi ezingaphezulu ngemini). Ukuba usebenzisa i-estrogen kunye neprogestin, akufuneki utshaye.

I-Estrogen kunye ne-progestin iringi yelungu lobufazi esetyenziselwa ukuthintela ukukhulelwa. I-Estrogen (i-ethinyl estradiol) kunye ne-progestin (etonogestrel okanye i-segesterone) ziihomoni ezimbini zesini sabasetyhini. I-Estrogen kunye neprogestin bakudidi lwamayeza abizwa ngokuba yindibaniselwano yokuthintela ukukhawula (iyeza lolawulo lokuzalwa). Umdibaniso we-estrogen kunye neprogestin usebenza ngokuthintela i-ovulation (ukukhutshwa kwamaqanda kwii-ovari). Baye batshintshe umgca wesibeleko (isibeleko) ukukhusela ukukhulelwa ekukhuleni kunye nokutshintsha i-mucus kwisibeleko (ukuvulwa kwesibeleko) ukukhusela isidoda (iiseli zokuzala) ukungena. Iiringi zangaphantsi zokuthintela ukukhulelwa ziyindlela esebenzayo kakhulu yolawulo lokuzalwa, kodwa azikuthinteli ukusasazeka kwintsholongwane yabantu (i-HIV, intsholongwane ebangela ukuba i-immunodeficiency syndrome [i-AIDS] kunye nezinye izifo ezosulela ngokwabelana ngesondo.

I-Estrogen kunye ne-progestin iringi yokuthintela ukukhulelwa iza njengeringi eguqukayo ukuyibeka kwilungu lobufazi. Izicwangcisi zokuthintela ukukhawula ze-estrogen kunye neprogestin zihlala zibekwa kwilungu lobufazi kwaye ziyekwe endaweni yeeveki ezi-3. Emva kweeveki ezi-3 usebenzisa iringi yelungu lobufazi, susa iringi ikhefu leveki e-1. Emva kokusebenzisa i-Annovera^® iringi yelungu lobufazi iiveki ezintathu, yicoce ngesepha ethambileyo kunye namanzi afudumeleyo, yipotoze yome ngelaphu okanye itawuli yephepha, emva koko uyibeke kwimeko enikiweyo ngexesha lekhefu leveki e-1. Emva kokusebenzisa iNuvaRing^® iringi yelungu lobufazi iiveki ezi-3, unokuyilahla kwaye ufake iringi yobufazi entsha emva kwekhefu leveki e-1. Qiniseka ukuba uyifaka iringi yakho yelungu lobufazi ekupheleni kwekhefu leveki e-1 kwangolo suku lunye kwaye kwangaxeshanye udla ngokufaka okanye ususe iringi, nokuba awukayekanga ukopha. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa iringi yokuthintela inzala kanye njengoko kuyalelwe.Ungaze usebenzise iiringi zokucwangcisa ezingaphezu kwesinye ngexesha kwaye usoloko uyifaka uyisuse iringi ngokokucwangciswa ngugqirha wakho.

Amakhonkco okhulelwa esini obufazi eza kwiimpawu ezahlukeneyo. Iimpawu ezahlukileyo zeringi zokuthintela ukukhulelwa ziqulathe amayeza okanye idosi ezahlukeneyo, zisetyenziswa ngeendlela ezahlukeneyo, kwaye zinobungozi kunye nezibonelelo ezahlukeneyo. Qiniseka ukuba uyazi ukuba loluphi uphawu lwendandatho yelungu lobufazi oyisebenzisayo kunye nendlela ekufuneka ulusebenzise ngayo. Buza ugqirha wakho okanye usokhemesti ikopi yolwazi lomenzi wesigulana kwaye uyifunde ngononophelo.

Ugqirha wakho uza kukuxelela xa kufuneka uyifakile iringi yakho yobukhomokazi yokuqala. Oku kuxhomekeke ekubeni ubusebenzisa olunye uhlobo lolawulo lokuzalwa kwinyanga ephelileyo, bebengasebenzisi uzalo, okanye usandula ukubeleka okanye ukhuphe isisu okanye ukukhupha isisu. Ngamanye amaxesha, unokufuna ukusebenzisa indlela eyongezelelweyo yolawulo lokuzalwa kwiintsuku ezisi-7 zokuqala usebenzisa iringi yothintelo. Ugqirha wakho uza kukuxelela ukuba ngaba ufuna ukusebenzisa ugcino lwasemva kokubeleka kwaye uya kukunceda ukhethe indlela, enjengeekhondom zamadoda kunye / okanye i-spermicides. Akufanele usebenzise i-diaphragm, ikepisi yomlomo wesibeleko, okanye ikhondom yabasetyhini xa iringi yothintelo ikho.

Ukuba usebenzisa iNuvaRing^® iringi yelungu lobufazi, faka umsesane omtsha emva kwekhefu leveki e-1; Phinda umjikelo weeveki ezi-3 zokusebenzisa ikhefu leveki e-1, usebenzisa iringi entsha yelungu lobufazi kumjikelo ngamnye.

Ukuba usebenzisa i-Annovera^® isangqa selungu lobufazi, faka kwakhona umsesane wesini ococekileyo emva kwekhefu leveki e-1; Phinda umjikelo weeveki ezi-3 zokusebenzisa ikhefu leveki e-1 ukuya kwi-13 imijikelezo.

Iringi yothintelo lokucwangcisa ihlala ihlala kwilungu lakho lobufazi de uyisuse. Ngamanye amaxesha inokuphuma xa ususa itampon, ngexesha lokwabelana ngesondo, okanye ukuhamba kwamathumbu. Fowunela ugqirha wakho ukuba iringi yakho yokuthintela ukukhuhla iphuma rhoqo.

Ukuba iNuvaRing yakho^® Iringi yokucwangcisa iyashibilika, kuya kufuneka uyihlambe ngamanzi apholileyo okanye adikidiki (hayi ashushu) kwaye uzame ukuyibuyisela kwisithuba seeyure ezintathu. Nangona kunjalo, ukuba iNuvaRing yakho^® Iringi yothintelo kukhulelwa iyaphuma kwaye yaphukile, yilahle endaweni yayo ufake iringi entsha yelungu lobufazi. Ukuba iringi yakho iyawa ize ilahleke, kuya kufuneka uyifakele iringi entsha kwaye uyisuse iringi entsha kwangaxeshanye bekucwangcisiwe ukuba ukhuphe iringi ebilahlekile. Ukuba awuyithathi indawo yeNuvaRing yakho^® iringi yelungu lobufazi ngaphakathi kwexesha elifanelekileyo, kufuneka usebenzise indlela engeyoyemvelo yokulawula ukuzalwa (umzekelo, iikhondom ezine-spermicide) de ube unayo iringi endaweni yeentsuku ezisi-7 zilandelelana.

Ukuba iAnnovera yakho^® iringi yelungu lobufazi iyawa, uyihlambe ngesepha epholileyo kunye namanzi ashushu, hlamba kwaye ubambe ngetawuli ecocekileyo okanye itawuli yephepha, uzame ukubuyisela kwisithuba seeyure ezimbini. Ukuba iringi yakho yelungu lobufazi ayikho endaweni ngaphezu kweeyure ezi-2 kumjikelo weeveki ezi-3 eza kufakwa iringi yelungu lobufazi (umz., Ukuwa kanye okanye amatyeli aliqela), kuya kufuneka usebenzise into engeyiyo ihomoni indlela yogcino yolawulo lokuzalwa (umzekelo, iikhondom ezine-spermicide) de ube unayo iringi endaweni yeentsuku ezisi-7 zilandelelana.

Rhoqo ujonge ubukho bendandatho yelungu lobufazi kwilungu lobufazi ngaphambi nasemva kokwabelana ngesondo.

Amakhonkco okhulelwa esini obufazi aya kusebenza kuphela ukuba asetyenziswa rhoqo. Sukuyeka ukusebenzisa amakhonkco obufazi ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-estrogen kunye neprogestin iringi yelungu lobufazi,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-etonogestrel, i-segesterone, i-ethinyl estradiol, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwisangqa se-estrogen kunye neprogestin yelungu lobufazi. Buza usokhemesti wakho uluhlu lwezinto ezikwi-estrogen kunye neprogestin iringi yelungu lobufazi.
• xelela ugqirha wakho ukuba uthatha indibaniselwano ye-ombitasvir, paritaprevir, kunye ne-ritonavir (Technivie) kunye okanye ngaphandle kwe-dasabuvir (eViekira Pak). Ugqirha wakho uya kukuxelela ukuba ungasebenzisi i-estrogen kunye ne-progestin iringi yelungu lobufazi ukuba uthatha elinye okanye ngaphezulu kula mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini kunye nezongezelelo zesondlo ozithathayo. Qiniseka ukuba ukhankanya oku kulandelayo: i-acetaminophen (iTylenol, abanye); izinto zokubulala ezifana ne-fluconazole (i-Diflucan), i-griseofulvin (i-Gris-Peg), i-itraconazole (i-Onmel, i-Sporanox), i-ketoconazole (i-Nizoral), i-miconazole (i-Oravig), kunye ne-voriconazole (Vfend); Aprepitant (Hlomela); ascorbic acid (ivithamin C); atorvastatin (Lipitor); barbiturates; i-boceprevir (iVictrelis; ayisafumaneki e-US); i-bosentan (iTracleer); icofibric acid; icyclosporine (Gengraf, Neoral, Sandimmune); amayeza e-HIV okanye i-AIDS afana ne-atazanavir (Reyataz), darunavir (Prezista) ene-ritonavir (Norvir), delavirdine (Rescriptor), efavirenz (Sustiva), etravirine (Intelence), indinavir (Crixivan), lopinavir (Kaletra), nelfinavir (Virus ), nevirapine (Viramune), ritonavir (Norvir), saquinavir (Invirase), kunye netipranavir (Aptivus); morphine (Astramorph, Kadian, nabanye); i-prednisolone (Orapred); irifabutin (Mycobutin); irifampin (Rifadin, Rimactane), rufinamide (Banzel); amayeza okubanjwa njenge-carbamazepine (Tegretol, Teril, abanye), felbamate (Felbatol), lamotrigine (Lamictal), oxcarbazepine (Trileptal), phenobarbital, phenytoin (Dilantin, Phenytek), kunye ne-topiramate (Topamax); telaprevir (Incivek; ayisafumaneki e-U.S); temazepam (Ukubuyisela kwakhona); theophylline (Elixophyllin, Theo-24, abanye); idlala lengqula; kunye ne-tizanidine (iZanaflex). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Kuya kufuneka usebenzise enye indlela yolawulo lokuzalwa ukuba uthatha amanye ala mayeza ngelixa usebenzisa iringi yokuthintela ukukhulelwa.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iimveliso eziqulathe iSt.
• xelela ugqirha wakho ukuba ukhe waba nomhlaza wamabele okanye nawuphi na umhlaza; isifo se-cerebrovascular (ukuvala okanye ukunciphisa amandla emithanjeni yegazi ngaphakathi kwengqondo okanye ekhokelela kwingqondo); ukubetha okanye ukubetha okuncinci; isifo semithambo yegazi (imithambo yegazi exineneyo ekhokelela entliziyweni); iintlungu zesifuba; isifo sentliziyo; amahlwili egazi emilenzeni okanye emiphungeni; i-cholesterol ephezulu okanye i-triglycerides; igazi elonyukayo; i-fibrillation ye-atrial; ukubetha kwentliziyo ngokungaqhelekanga; nayiphi na imeko echaphazela iivalves zentliziyo yakho (iziqwenga zomzimba ezivulekileyo kwaye zisondele ukulawula ukuhamba kwegazi entliziyweni); isifo seswekile kwaye bangaphezulu kweminyaka engama-35 ubudala; isifo seswekile kunye noxinzelelo lwegazi okanye iingxaki zezintso zakho, imithambo yegazi, amehlo, okanye imithambo-luvo; isifo seswekile ngaphezu kweminyaka engama-20; isifo seswekile esichaphazele ukujikeleza kwegazi lakho; iintloko eziza kunye nezinye iimpawu ezinje ngokutshintsha kombono, ubuthathaka, kunye nesiyezi; migraine (ukuba ungaphezulu kweminyaka engama-35); izilonda zesibindi okanye isifo sesibindi; ukopha okanye iingxaki zokunqanda igazi; ukopha okungachazwanga kwilungu lobufazi; okanye i-hepatitis okanye ezinye iintlobo zesifo sesibindi. Ugqirha wakho uya kukuxelela ukuba ungasebenzisi iringi ye-estrogen kunye neprogestin yelungu lobufazi.
• xelela ugqirha wakho ukuba usandula ukuba nosana, ukuphuphuma kwesisu, okanye ukukhupha isisu. Kwakhona xelela ugqirha wakho ukuba ukhe wanayo i-jaundice (ubumthubi besikhumba okanye amehlo); iingxaki zesifuba ezinje nge-mammogram engaqhelekanga okanye i-x-ray yebele, amaqhuqhuva ebele, isifo sesifuba se-fibrocystic; Imbali yosapho yomhlaza wamabele; ukuxhuzula; ukudakumba; i-melasma (amabala amdaka ebusweni); i-bladder, isibeleko okanye i-rectum eye yawela okanye yabhobhoza kwilungu lobufazi; nayiphi na imeko eyenza ukuba ubufazi bakho bube nakho ukucaphuka; isifo sokudakumba esinetyhefu (usulelo lwebhaktiriya); i-angioedema yelifa (imeko ezuzwe njengelifa ebangela iziqendu zokudumba ezandleni, iinyawo, ubuso, indlela yomoya, okanye amathumbu); okanye izintso, idlala lengqula, okanye isifo senyongo.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwa ngelixa usebenzisa i-estrogen kunye neprogestin iringi yelungu lobufazi, tsalela ugqirha ngokukhawuleza. Kuya kufuneka ukrokrele ukuba ukhulelwe kwaye ubize ugqirha wakho ukuba uyisebenzise ngokuchanekileyo iringi yothintelo kwaye uphose amaxesha amabini ngokulandelelana, okanye ukuba awuyisebenzisanga iringi yokuthintela ukukhulelwa ngokwemiyalelo kwaye uphulukana nexesha elinye. Akufanelanga ukuncancisa xa usebenzisa iringi yothintelo.
• ukuba wenza utyando, xelela ugqirha ukuba usebenzisa iringi ye-estrogen kunye neprogestin yelungu lobufazi. Ugqirha wakho angakucela ukuba uyeke ukusebenzisa iringi yelungu lobufazi okungenani iiveki ezi-4 ngaphambili kunye nokuya kuthi ga kwiiveki ezi-2 emva kotyando oluthile.

Thetha nogqirha wakho malunga nokusela ijusi yamagilebhisi ngelixa usebenzisa eli yeza.

Yonke into ephawulwayo yeringi yelungu lobufazi ineendlela ezithile ekufuneka zilandelwe malunga nokususa kunye / okanye ukufaka iringi yothintelo. Ngononophelo funda imikhombandlela kulwazi lomenzi wesigulana esize neringi yakho yento yokucwangcisa. Ukuba awuyifaki iringi yelungu lobufazi ngokwemiyalelo okanye uyiphosile idosi, kuyakufuneka usebenzise indlela yokubuyela umva yolawulo lokuzalwa. Sukusebenzisa isangqa esinye sangaphezulu ngexesha elinye. Ukuba unemibuzo, biza ugqirha wakho okanye usokhemesti.

Iringi yangaphantsi ye-Estrogen kunye neprogestin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudumba, ukuba bomvu, ukurhawuzelela, ukutshisa, ukurhawuzelela, okanye usulelo lobufazi
• ukuphuma okumhlophe okanye okumthubi okumhlophe
• ukopha kwilungu lobufazi okanye ukubonwa xa kungelilo ixesha lakho
• ukuthamba kwebele okungaqhelekanga
• intloko ebuhlungu
• isicaphucaphu
• ukugabha
• urhudo
• ubunzima okanye ukulahleka
• iintlungu zebele, ukuthamba, okanye ukungonwabi
• Ukungahambi kakuhle kwelungu lobufazi okanye uvakalelo lomzimba welinye ilizwe
• isisu esibuhlungu
• induna
• utshintsho kwiminqweno yesini

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo biza ugqirha ngokukhawuleza:

• intlungu emva komlenze ongezantsi
• ebukhali, ngesiquphe, okanye ukutyumza iintlungu esifubeni
• ubunzima esifubeni
• ukuphefumla ngokukhawuleza
• intloko ebukhali ngesiquphe, ukugabha, isiyezi, okanye isiqaqa
• iingxaki ngesiquphe ngentetho
• ubuthathaka okanye ukuba ndindisholo kwengalo okanye umlenze
• umbono ophindwe kabini, umbono ophazamisayo, okanye olunye utshintsho kumbono
• amabala amnyama esikhumba ebunzi, izidlele, imilebe ephezulu, kunye / okanye isilevu
• ubumthubi besikhumba okanye amehlo; ukuphelelwa ngumdla wokutya; umchamo omnyama; ukudinwa kakhulu; ubuthathaka; okanye ukuhamba kwesisu okukhanyayo
• umkhuhlane omkhulu ngokukhawuleza, ukugabha, urhudo, ukuphelelwa ngamandla okanye ukuziva utyhafile xa umile, irhashalala, iintlungu zemisipha, okanye isiyezi
• ukudakumba; ubunzima bokulala okanye ukulala; ukulahleka kwamandla; okanye olunye utshintsho lweemvakalelo
• irhashalala; ukudumba kwezandla, iinyawo, amaqatha, okanye imilenze esezantsi; imihlathi okanye ukurhawuzelela

I-Estrogen kunye ne-progestin iringi yelungu lobufazi inokunyusa amathuba okuba ube nezihlunu zesibindi. Ezi tumors ayilulo uhlobo lomhlaza, kodwa zinokwaphula kwaye zibangele ukopha kakhulu emzimbeni. Thetha nogqirha wakho malunga neengozi zokusebenzisa iringi yokuthintela ukukhulelwa.

Iringi ye-Estrogen kunye neprogestin yelungu lobufazi inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nelanga elithe ngqo, ubushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Musa ukusifaka efrijini okanye siyiqande. Lahla iNuvaRing^® emva komhla wokuphelelwa ukuba ayisetyenziswanga kwisakhethi enikiweyo (foil poch) kwaye emva koko ungene kumgqomo wenkunkuma. Sukugungxula iringi yelungu lobufazi kwindlu yangasese.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukopha
• isicaphucaphu
• ukugabha

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Landela izikhokelo zikagqirha wakho zokuvavanya amabele akho; Xela onke amaqhuma ngokukhawuleza.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba usebenzisa iringi ye-estrogen kunye neprogestin yelungu lobufazi.

Sukusebenzisa ioyile esekwe (kubandakanya i-silicone-esekwe) izinto zokuthambisa zangasese kunye neAnnovera^® iringi yelungu lobufazi.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Annovera^® (iqulethe i-Ethinyl Estradiol, Segesterone)
• UNuvaRing^® (iqulethe i-Ethinyl Estradiol, i-Etonogestrel)

• isangqa sokucwangcisa