Inaliti yePramlintide

Umxholo

• Umngcipheko we-hypoglycemia unokuba mkhulu kwiimeko ezithile. Biza ugqirha wakho ukuba uceba ukusebenza ngakumbi kunesiqhelo. Ukuba unayo nayiphi na le miqathango ilandelayo akufuneki usebenzise ipramlintide kwaye kufuneka ubize ugqirha wakho ukuba afumanise ukuba wenzeni:
• Ngaphambi kokusebenzisa inaliti ye-pramlintide,
• Ipramlintide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

Uya kusebenzisa i-pramlintide kunye nexesha lokutya le-insulin ukulawula amanqanaba eswekile yegazi. Xa usebenzisa i-insulin, kukho ithuba lokuba uya kuba ne-hypoglycemia (iswekile esezantsi yegazi). Lo mngcipheko unokuba mkhulu ngexesha lokuqala kweeyure ezintathu emva kokuba ufakele i-pramlintide, ngakumbi ukuba une-1 yeswekile (imeko apho umzimba ungayivelisi i-insulin kwaye ngenxa yoko awukwazi ukulawula ubungakanani beswekile egazini). Unokuzenzakalisa okanye wenzakalise ukuba iswekile yegazi lakho iyehla ngelixa ubandakanyeka kwimisebenzi efuna ukuba uqaphele okanye ucinge ngokucacileyo. Sukuqhuba imoto okanye usebenzise oomatshini abasindayo de ube uyazi ukuba ipramlintide iyichaphazela njani iswekile esegazini lakho. Thetha nogqirha wakho malunga neminye imisebenzi ekufuneka uyiphephe ngelixa usebenzisa i-pramlintide.

Xelela ugqirha wakho ukuba unesifo seswekile ixesha elide, ukuba unesifo seswekile, ukuba awukwazi ukuxelela xa iswekile yegazi iphantsi, ukuba ufuna unyango lwe-hypoglycemia amatyeli aliqela kwiinyanga ezi-6 ezidlulileyo ,, okanye ukuba une-gastroparesis (ukucothiswa kokuhamba kokutya ukusuka esiswini ukuya emathunjini amancinci. Ugqirha wakho uyakukuxelela ukuba ungasebenzisi i-pramlintide. Xelela ugqirha wakho ukuba uthatha nawaphi na amayeza alandelayo: i-angiotensin eguqula i-enzyme (ACE) inhibitors esetyenziselwa ukunyanga uxinzelelo lwegazi oluphezulu, isifo sentliziyo, okanye isifo sesifo seswekile; ii-beta blockers ezinjenge-atenolol (kwi-Tenoretic), i-labetalol (iTrandate), i-metoprolol (i-Lopressor, i-Toprol XL, kwi-Dutoprol, kwi-Lopressor HCT), nadolol (Corgard, e-Corzide), kunye nepropranolol (Hemangeol, Inderal, Innopran, eInderide); clonidine (Catapres, Duraclon, Kapvay, eClorpres); disopyramide (Norpace); Isimboli); gemfibrozil (L i-opid); i-guanethidine (Ismelin; ayisekho e-U.S.); amanye amayeza eswekile; I-lanreotide (iSomatuline Depot); i-monoamine oxidase (MAO) inhibitors enjenge-isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), kunye ne-tranylcypromine (iParnate); ipentoxifylline (Pentoxil); ipropoxyphene (iDarvon; ayisasebenzi e-US); gqithisela; iintlungu ze-salicylate ziyanceda njenge-aspirin; kunye ne-sulfonamide antibiotics efana ne-trimethoprim / sulfamethoxazole (Bactrim, Septra).

Ngelixa usebenzisa i-pramlintide, kufuneka ulinganise iswekile yegazi ngaphambi nasemva kwesidlo ngasinye nangexesha lokulala. Kananjalo kuya kufuneka ukuba ubone okanye uthethe nogqirha wakho rhoqo, kwaye utshintshe rhoqo iidosi zakho zepramlintide kunye ne-insulin ngokwemiyalelo kagqirha wakho. Tshela ugqirha wakho ukuba ucinga ukuba kuya kuba nzima kuwe ukwenza ezi zinto, ukuba unengxaki yokujonga iswekile yegazi okanye ukusebenzisa i-insulin yakho ngokuchanekileyo ngaphambili, okanye ukuba ukufumanisa kunzima ukulawula unyango emva kokuba uqale ukusebenzisa inyani.

Ugqirha wakho uya kunciphisa idosi yakho ye-insulin xa uqala ukusebenzisa ipramlintide. Ugqirha wakho uza kukuqala ngedosi esezantsi yepramlintide kwaye uya kuyonyusa kancinci idosi yakho. Biza ugqirha wakho ngoko nangoko ukuba unesiyezi na ngeli xesha; idosi yakho inokufuna ukuba itshintshwe okanye kungafuneka uyeke ukusebenzisa ipramlintide. Ugqirha wakho uya kutshintsha idosi yakho ye-insulin nje ukuba usebenzise idosi yepramlintide ekulungeleyo. Landela yonke le miyalelo ngononophelo kwaye ubuze ugqirha wakho okanye usokhemesti kwangoko ukuba awuqinisekanga ukuba ingakanani i-insulin okanye ipramlintide ekufuneka uyisebenzisile.

Umngcipheko we-hypoglycemia unokuba mkhulu kwiimeko ezithile. Biza ugqirha wakho ukuba uceba ukusebenza ngakumbi kunesiqhelo. Ukuba unayo nayiphi na le miqathango ilandelayo akufuneki usebenzise ipramlintide kwaye kufuneka ubize ugqirha wakho ukuba afumanise ukuba wenzeni:

• uceba ukutsiba isidlo.
• uceba ukutya isidlo esineekhalori ezingaphantsi kwama-250 okanye iigrama ezingama-30 zeecarbohydrate.
• awukwazi kutya kuba ugula.
• ngekhe utye ngenxa yokuba ucwangciselwe uqhaqho okanye uvavanyo lwezonyango.
• iswekile yegazi lakho liphantsi kakhulu phambi kokutya.

Utywala bunokubangela ukwehla kweswekile yegazi. Buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa usebenzisa i-pramlintide.

Biza ugqirha wakho ngoko nangoko ukuba iswekile esegazini lakho iphantsi kunesiqhelo okanye ukuba unazo naziphi na kwezi mpawu zeswekile esezantsi yegazi: indlala, intloko ebuhlungu, ukubila, ukushukuma kwenxalenye yomzimba wakho ongakwaziyo ukuwulawula, ukuba nochuku, ukuba nzima ukugxila, Ukuphulukana nokuqonda, isiqaqa, okanye ukuxhuzula. Qiniseka ukuba uhlala unomthombo osebenzayo ngokukhawuleza weswekile efana neelekese ezinzima, ijusi, iipilisi zeswekile, okanye i-glucagon ekhoyo ukunyanga i-hypoglycemia.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngepramlintide kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungasifumana nesikhokelo samayeza kwiwebhusayithi ye-FDA: http://www.fda.gov.

Ipramlintide isetyenziswa ngexesha lokutya i-insulin ukulawula amanqanaba eswekile yegazi kubantu abanesifo seswekile. Ipramlintide isetyenziselwa ukunyanga abaguli abaneswekile yegazi engalawulwa yi-insulin okanye i-insulin kunye nonyango lomlomo lweswekile. Ipramlintide ikwiklasi yamayeza abizwa ngokuba yi-antihyperglycemics. Isebenza ngokunciphisa ukuhamba kokutya ngesisu. Oku kuthintela iswekile esegazini ukuba inyuke kakhulu emva kokutya, kwaye inganciphisa ukutya kwaye ibangele ukwehla kobunzima.

Ixesha elingaphezulu, abantu abanesifo seswekile kunye neswekile ephezulu yegazi banokuba neengxaki ezinzulu okanye ezisongela ubomi, kubandakanya isifo sentliziyo, ukubetha, iingxaki zezintso, ukonakala kwemithambo-luvo kunye neengxaki zamehlo. Sebenzisa amayeza, ukwenza utshintsho kwindlela yokuphila (umzekelo, ukutya, ukwenza umthambo, ukuyeka ukutshaya), kunye nokujonga iswekile yegazi rhoqo kunokunceda ukulawula isifo seswekile kunye nokuphucula impilo yakho. Olu nyango lunokunciphisa amathuba akho okuhlaselwa sisifo sentliziyo, ukubetha, okanye ezinye iingxaki ezinxulumene nesifo seswekile ezinje ngokusilela kwezintso, ukulimala kwentliziyo (ukubindeka, imilenze ebandayo okanye iinyawo; ukunciphisa amandla ezesondo kumadoda nabasetyhini), iingxaki zamehlo, kubandakanya notshintsho okanye ukulahleka kombono, okanye isifo seentsini. Ugqirha wakho kunye nabanye ababoneleli ngempilo bayakuthetha nawe ngeyona ndlela yokulawula isifo sakho seswekile.

I-Pramlintide iza njengesisombululo (ulwelo) kwipeni yedosi ekhethiweyo yokufaka inaliti (phantsi nje kwesikhumba). Ihlala itofwe izihlandlo ezininzi ngemini, ngaphambi kwesidlo ngasinye kubandakanya ubuncinci i-250 yeekhalori okanye iigrama ezingama-30 ze-carbohydrate. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa pramlintide ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Ipramlintide ilawula isifo seswekile kodwa ayisinyangi. Qhubeka nokusebenzisa i-pramlintide nokuba uziva uphilile. Sukuyeka ukusebenzisa i-pramlintide ngaphandle kokuthetha nogqirha wakho. Ukuba uyeka ukusebenzisa i-pramlintide nangasiphi na isizathu, ungaqali ukuyisebenzisa kwakhona ngaphandle kokuthetha nogqirha wakho.

Qiniseka ukuba uyazi ukuba loluphi olunye unikezelo, olunjengeenaliti, kuya kufuneka ukuba utofe iyeza lakho. Buza ugqirha wakho okanye usokhemesti ukuba loluphi uhlobo lweenaliti oza kuzidinga ukujova amayeza akho. Funda ngononophelo kwaye uqonde imiyalelo yomenzi wokufaka inaliti yepramlintide usebenzisa usiba. Qiniseka ukuba uyazi ukuba uyicwangcisa njani kwaye nini ipeni entsha. Buza ugqirha wakho okanye usokhemisti akubonise indlela yokusebenzisa usiba. Landela izikhokelo ngononophelo. Musa ukudibanisa ipramlintide kunye ne-insulin.

Soloko ujonga isisombululo sakho sepramlintide ngaphambi kokuba uyitofe. Kufuneka icace kwaye ingenambala. Sukusebenzisa i-pramlintide ukuba inemibala, inamafu, iyajiya, iqulethe amasuntswana aqinileyo, okanye ukuba umhla wokuphelelwa kwileyibhile yephakheji udlulile.

Ungaze uphinde usebenzise iinaliti kwaye ungaze wabelane ngeenaliti okanye iipeni. Soloko uyisusa inaliti emva kokuba utofile idosi yakho. Lahla iinaliti kwisitya esinganyangekiyo. Buza ugqirha wakho okanye usokhemesti ngendlela yokusilahla isikhongozeli esinganyangekiyo.

Ungayifaka ipramlintide naphina esiswini okanye ethangeni. Musa ukufaka ipramlintide engalweni yakho. Khetha indawo eyahlukileyo yokujova ipramlintide yonke imihla. Qiniseka ukuba indawo oyikhethileyo ingaphezulu kweesentimitha ezi-2 ukusuka kwindawo oza kuyifaka kuyo i-insulin.

Kuya kufuneka ungenise ipramlintide phantsi kolusu ngendlela efanayo naleyo yokujova ngayo i-insulin. Vumela ipeni ye-pramlintide ifudumale kubushushu begumbi ngaphambi kokuba utofe iyeza. Ukuba unemibuzo malunga nokufaka i-pramlintide, buza ugqirha wakho okanye usokhemesti.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti ye-pramlintide,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nepramlintide, nawaphi na amanye amayeza, i-metacresol, okanye naziphi na ezinye izithako kwipeni ye-pramlintide. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye neemveliso zamayeza owathathayo. Qinisekisa ukukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayo nayiphi na kwezi zilandelayo: acarbose (Precose); antihistamines; iatropine (Atropen, eLomotil, abanye); ezinye izidambisi zengqondo ('mood elevators') ezibizwa ngokuba yi-tricyclic antidepressants; amayeza athile okunyanga isifuba, isifo sorhudo, isifo semiphunga, ukugula ngengqondo, ukugula okushukumayo, isinyi kakhulu, iintlungu, isifo sikaParkinson, isisu okanye amaqhuma emathumbu, izilonda, kunye nesisu esibuhlungu; laxatives; miglitol (iGlyset); kunye nezithambisi zesitulo. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukuba uthatha izinto zokucwangcisa ngomlomo (iipilisi zolawulo lokuzalwa), amayeza eentlungu, okanye amayeza okubulala iintsholongwane, thatha ubuncinci iyure enye ngaphambi okanye kwiiyure ezimbini emva kokusebenzisa ipramlintide.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa usebenzisa i-pramlintide, tsalela ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa ipramlintide.

Ugqirha wakho, utya ukutya, okanye utitshala weswekile uya kukunceda wenze isicwangciso sokutya esikusebenzelayo. Landela isicwangciso sokutya ngononophelo.

Tsiba idosi ephosiweyo kwaye usebenzise idosi yakho yesiqhelo yepramlintide ngaphambi kwesidlo esikhulu esilandelayo. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo.

Ipramlintide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ububomvu, ukudumba, ukugruzuka, okanye ukurhawuzelela kwindawo yenaliti yepramlintide
• Ukuphelelwa ngumdla wokutya
• isisu esibuhlungu
• ukudinwa kakhulu
• isiyezi
• ukukhohlela
• umqala obuhkungu
• intlungu edibeneyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na iimpawu ezidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko.

Ipramlintide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina izibaya zepramlintide ezingavulwanga kwifriji kwaye ukhusele ekukhanyeni; ungafrizi zisihlwayo. Lahla nayiphi na ipeni ebikhenkcezisiwe okanye ivezwe bubushushu. Ungagcina iipeni zepramlintide ezivuliweyo kwifriji okanye kubushushu begumbi, kodwa kufuneka uzisebenzise zingadlulanga iintsuku ezingama-30. Lahla nayiphi na ipeni ye-pramlintide evulekileyo emva kweentsuku ezingama-30.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• isisu esimoshakele
• ukugabha
• urhudo
• isiyezi
• ukugungxula

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ipeni yeSymlin^®